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Spatio-temporal variation in rock exhumation linked to large-scale shear zones in the southeastern Tibetan Plateau

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Science China Earth Sciences 2020年第4期63卷 512-532页

作者： Yukui GE Jing LIU-ZENG Jinyu ZHANG Wei wang Yuntao TIAN Matthew FOX Lingsen ZENG Xiaoming SHEN heng wang Ze SU Kejia XIE State Key Laboratory of Earthquake Dynamics Institute of GeologyChina Earthquake AdministrationBeijing 100029China Institute of Surface-Earth System Science Tianjin UniversityTianjin 300072China Guangdong Provincial Key Laboratory of Geodynamics and Geohazards School of Earth Sciences and EngineeringSun Yat-sen UniversityGuangzhou 510275China Department of Earth Sciences University College LondonWC1E 6BTUK Key Laboratory of Deep-Earth Dynamics Ministry of Natural ResourcesInstitute of GeologyChinese Academy of Geological SciencesBeijing 100037China Key Laboratory of Crustal Dynamics Institute of Crustal DynamicsChina Earthquake AdministrationBeijing 100085China Henan Province Non-ferrous Metals Geological Mineral Resources Bureau Zhengzhou 450016.China

Crustal-scale shear zones are believed to have played an important role in the tectonic and landscape evolution of orogens. However, the variation of long-term rock exhumation between the interior of shear zones and adjacent regions has not been documented in detail. In this study, we obtained new zircon U-Pb, biotite ^(40)Ar/^(39)Ar, zircon and apatite(U-Th)/He data, and conducted inverse thermal history modeling from two age-elevation profiles(the Pianma and Tu'er profiles) in the southeastern Tibetan Plateau. Our goal is to constrain the exhumation history of the Gaoligong and Chongshan shear zones and adjacent regions, so as to explore the effect of the shear zones on exhumation and their thermal effect on cooling that should not be ignored. Our results suggest that during the interval of 18–11 Ma the exhumation rates of rocks within the Gaoligong shear zone are anomalously high compared with those outside of. The rapid cooling during 18–11 Ma appears to be restricted to the shear zone, likely due to localized thermal effects of shearing and exhumation. After 11 Ma, both the areas within and outside of the shear zones experienced a similar two-stage exhumation history: slower cooling until the early Pliocene, and then a rapid increase in cooling rate since the early Pliocene. Our results indicate a synchronized exhumation but with spatially varied exhumation rates. Our study also highlights the important role of large-scale shear zones in exposing rocks, and thus the importance of the structural context when interpreting thermochronological data in the southeastern margin of the Tibetan Plateau.

关键词： Southeastern Tibetan Plateau Exhumation (U-Th)/He Low-temperature thermochronometry Shear zone

A framework of force of information influence and application for C4KISR system

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Journal of Systems Engineering and Electronics 2024年第2期35卷 430-443页

作者： MAO Shaojie DIAO Lianwang SUN Yu wang heng YI Kan XU Xin MAO Xiaobin ZHANG Kecheng Sheng Long Science and Technology on Information Systems Engineering Laboratory The 28th Research Institute of China Electronics Technology Group CorporationNanjing 210007China Unit 94860 of the PLA Nanjing 210008China

The subversive nature of information war lies not only in the information itself, but also in the circulation and application of information. It has always been a challenge to quantitatively analyze the function and effect of information flow through command, control, communications, computer, kill, intelligence,surveillance, reconnaissance (C4KISR) system. In this work, we propose a framework of force of information influence and the methods for calculating the force of information influence between C4KISR nodes of sensing, intelligence processing,decision making and fire attack. Specifically, the basic concept of force of information influence between nodes in C4KISR system is formally proposed and its mathematical definition is provided. Then, based on the information entropy theory, the model of force of information influence between C4KISR system nodes is constructed. Finally, the simulation experiments have been performed under an air defense and attack scenario. The experimental results show that, with the proposed force of information influence framework, we can effectively evaluate the contribution of information circulation through different C4KISR system nodes to the corresponding tasks. Our framework of force of information influence can also serve as an effective tool for the design and dynamic reconfiguration of C4KISR system architecture.

关键词： information warfare command control communications computer kill intelligence surveillance reconnaissance(C4KISR)system information circulation force of information influence information entropy

Molecular characterization and expression of the SiUCP2 gene in sea urchin Strongylocentrotus intermedius

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Journal of Oceanology and Limnology 2021年第4期39卷 1523-1537页

作者： Lingshu HAN Zijiao QUAN Bing HAN Beichen DING Xiaofang HUANG heng wang Yaqing CHANG Jun DING Key Laboratory of Mariculture&Stock Enhancement in North China's Sea Ministry of Agriculture and Rural Aff airsDalian Ocean UniversityDalian 116023China

Uncoupling protein 2 (UCP2) is a proton transporter located in the inner mitochondrial membrane, and inhibits the formation of adenosine triphosphate and reactive oxygen species by uncoupling oxidative phosphorylation. To provide a theoretical basis for the role of SiUCP2 in lipid metabolism, a 2 341-bp full-length cDNA of SiUCP2 from sea urchin Strongylocentrotus intermedius , which encodes 323 amino acids (predicted MW 36.11 kDa) was obtained, and the structure and function of the SiUCP2 gene and its expression at the mRNA and protein level were studied. SiUCP2 had high homology with UCP2 of other species. Expression of SiUCP2 was detected in the order of tube feet > gonads > coelomocytes > intestines. The expression level was the highest in prismatic larvae and lowest in the two-cell stage. Moreover, using in-situ hybridization, we found that SiUCP2 protein was expressed in the gonads and intestine. This study provided a theoretical basis for subsequent studies on the role of SiUCP2 and its regulatory mechanism in lipid metabolism, and for the improvement of gonad quality to obtain a higher economic value from sea urchins.

关键词： Strongylocentrotus intermedius SiUCP2 gene cloning lipid metabolism in-situ hybridization western blot

AN ITERATIVE PROCEDURE FOR DOMAIN DECOMPOSITION METHOD OF SECOND ORDER ELLIPTIC PROBLEM WITH MIXED BOUNDARY CONDITIONS

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Journal of Computational Mathematics 1997年第4期15卷 319-326页

作者： Lie-heng wang (State Key Laboratory of Scientific and Engineering Computing, ICMSEC, Chinese Academy of Sciences, Beijing, China) 中科院计算数学与科学工程计算所科学与工程计算国家重点实验室北京

This paper is devoted to study of an iterative procedure for domain decomposition method of second order elliptic problem with mixed boundary conditions (i.e., Dirichlet condition on a part of boundary and Neumann condition on the another part of boundary). For the pure Dirichlet problem, Marini and Quarteroni [3], [4] considered a similar approach, which is extended to more complex problem in this paper.

关键词： EH Math AN ITERATIVE PROCEDURE FOR DOMAIN DECOMPOSITION METHOD OF SECOND ORDER ELLIPTIC PROBLEM WITH MIXED BOUNDARY CONDITIONS

Altered metabolic state impedes limb regeneration in salamanders

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Zoological Research 2021年第6期42卷 772-782页

作者： Zhe-Lun Peng Bin-Xu Yin Rui-Min Ren Yin-Long Liao Hao Cai heng wang College of Animal Sciences and Technology Huazhong Agricultural UniversityWuhanHubei 430070China Shenzhen Institute of Nutrition and Health Huazhong Agricultural UniversityShenzhenGuangdong 518120China Shenzhen Branch Guangdong Laboratory for Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhenGuangdong 518120China

Salamanders are unique among tetrapods in their ability to regenerate the limbs throughout *** other poikilothermic amphibians,salamanders also show a remarkable capacity to survive long periods of *** the physiological reserves necessary for tissue regeneration are preserved or sacrificed in starved salamanders is *** the current study,we maintained Iberian ribbed newts(Pleurodeles waltl)under extreme physiological stress to assess the extent of regeneration and identify the molecular and cellular changes that may occur under such *** 19 months of complete food deprivation,the animals exhibited extensive morphological and physiological adaptations but remained behaviorally active and *** was elevated in different tissues and the transformed gut microbiota indicated remodeling of the intestinal tract related to *** limb amputation in animals starved for 21 months,regeneration proceeded with progenitor cell proliferation and migration,leading to limb blastema ***,limb outgrowth and patterning were substantially *** of autophagy inhibited cell proliferation and blastema formation in starved animals,but not in fed ***,tissue autophagy and the regenerative response were tightly coupled only when animals were under *** results demonstrate that under adverse conditions,salamanders can exploit alternative strategies to secure blastema formation for limb regeneration.

关键词： Starvation Stress Autophagy Regeneration Salamander

Alkaloids of Nitraria sibirica Pall. decrease hypertension and albuminuria in angiotensin II-salt hypertension

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Chinese Journal of Natural Medicines 2014年第4期12卷 266-272页

作者： Mahinur Bakri YI Yang CHEN Ling-Dan Haji Akber Aisa wang Mong-heng The Key Laboratory of Plant Resources and Chemistry of Arid Zone Xinjiang Technical Institute of Physics and ChemistryChinese Academy of Sciences State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization Xinjiang Technical Institute of Physics and ChemistryChinese Academy of Sciences Department of Physiology Georgia Regents University

In traditional Chinese medicine, Nitraria sibirica Pall.(Nitrariaceae) is used to treat hypertension. This study determined the effects of the total alkaloids of the leaves of Nitraria sibirica(NSTA) on blood pressure and albuminuria in mice treated with angiotensin II and a high-salt diet(ANG/HS). Adult mice were divided into three groups: control; infused with angiotensin II and fed a diet containing 4% NaCl(ANG/HS; and ANG/HS plus injection of NSTA(1 mg·kg-1·d-1, i.p.). After treatment of these regimens, daily water and food intake, kidney weight, blood pressure, urinary albumin excretion, renal concentrations of inflammatory markers, including soluble intercellular adhesion molecule-1(sICAM-1) and monocyte chemoattractant protein-1(MCP-1), and the expression of renal fibrosis markers were determined. Compared to the control group, the ANG/HS group had higher blood pressure and urinary albumin excretion. Treatment with NSTA in ANG/HS mice for three weeks significantly reduced blood pressure and urinary albumin excretion. ANG/HS treatment caused elevated levels of sICAM-1 and MCP-1, as well as increased fibrosis markers. Concurrent treatment with ANG/HS and NSTA attenuated the levels and expression of renal inflammatory and fibrosis markers. Treatment with NSTA effectively reduces hypertension-induced albuminuria through the reduction of renal inflammatory and fibrosis markers.

关键词： Nitraria sibirica Alkaloids Blood pressure High salt diet Hypertension Albuminuria

Impacts of human interventions on the seasonal and nodal dynamics of the M_(2)and K_(1)tidal constituents in Lingdingyang Bay of the Zhujiang River Delta,China

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Acta Oceanologica Sinica 2021年第10期40卷 49-64页

作者： Ping Zhang Qingshu Yang Haidong Pan heng wang Meifang Xie Huayang Cai Nanyang Chu Liangwen Jia Institute of Estuarine and Coastal Research School of Marine Engineering and TechnologySun Yat-sen UniversityZhuhai 519082China Guangdong Provincial Engineering Research Center of Coasts Islands and ReefsZhuhai 519082China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China Key Laboratory of Physical Oceanography Ministry of EducationQingdao 266100China School of Marine Science Sun Yat-sen UniversityZhuhai 519082China

Natural and human-induced changes may exert considerable impacts on the seasonal and nodal dynamics of M2 and K1 tidal ***,quantifying the influences of these factors on tidal regime changes is essential for sustainable water resources management in coastal *** this study,the enhanced harmonic analysis was applied to extract the seasonal variability of the M2 and K1 tidal amplitudes and phases at three gauging stations along Lingdingyang Bay of the Zhujiang River *** seasonal dynamics in terms of tidal wave celerity and amplification/damping rate were used to quantify the impacts of human-induced estuarine morphological alterations on M2 and K1 tidal hydrodynamics in inner and outer Lingdingyang *** results show that both tidal amplification/damping rate and wave celerity were considerably increased from the pre-anthropogenic activity period(Pre-AAP)to the post-anthropogenic activity period(Post-AAP)excepting the tidal amplification/damping rate in outer Lingdingyang Bay,and the variations in outer Lingdingyang Bay was larger than those in inner Lingdingyang *** alterations in these two parameters were more significant in flood season than in dry season in both inner and outer Lingdingyang *** seasonal variability of M2 and K1 tidal amplitudes were further quantified using a regression model accounting for the 18.61-year lunar nodal modulation,where this study observes a considerable alteration in M2 constituent owing to human *** the Post-AAP,the M2 amplitudes at the downstream station were larger than those that would have occurred in the absence of strong human interventions,whereas the opposite was true for the upstream station,leading to a substantial decrease in tidal amplification in outer Lingdingyang ***,it is opposite in inner Lingdingyang *** underlying mechanism can be primarily attributed to channel deepening and narrowing caused by human interventions,that resulted in substan

关键词： tidal dynamics S_(T)IDE model nodal modulation channel deepening tidal wave celerity

ON A SET OF h-HARMONIC HOMOGENEOUS POLYNOMIALS

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Analysis in Theory and Applications 2003年第3期19卷 234-237页

作者： wang Renhong Zhou heng (Dalian University of Technology, China) Institute of Mathematical Sciences Dalian University of Technology Dalian P. R. China

In this paper, we study the homogeneous polynomials orthogonal with the weight function h(x (d))=x 2k 1 1…x 2k d d on S d-1. We obtain the explicit formula on a basis of the orthogonal homogeneous polynomials of degree n. It is simpler than the formula in [2], and can be regarded as an extension of [1] under the weighted case.

关键词： h-harmonic homogeneous polynomials weight functions

Natural medicine can substitute antibiotics in animal husbandry:protective effects and mechanisms of rosewood essential oil against Salmonella infection

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Chinese Journal of Natural Medicines 2024年第9期22卷 785-796页

作者： wang Lanqiao FANG Juan wang heng ZHANG Baoyu wang Nan YAO Xinyu LI He QIU Jiazhang DENG Xuming LENG Bingfeng wang Jianfeng TAN Wenxi ZHANG Qiaoling State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationInstitute of Zoonosisand College of Veterinary MedicineJilin UniversityChangchun 130062China Shenzhen Beichen Biotech Co. Ltd.Shenzhen 518057China Department of Obstetrics and Gynecology The Second Hospital of Jilin UniversityChangchun 130041China

Aniba rosaeodora essential oil(RO) has been traditionally used in natural medicine as a substitute for antibiotics due to its notable antidepressant and antibacterial properties. Salmonella, a prevalent pathogen in foodborne illnesses, presents a major challenge to current antibiotic treatments. However, the antibacterial efficacy and mechanisms of action of RO against Salmonella spp. remain underexplored. This study aims to elucidate the chemical composition of RO, evaluate its antibacterial activity and mechanisms against Salmonella in vitro, and further delineate its anti-inflammatory mechanisms in vivo during Salmonella infection. Gas chromatography-mass spectrometry(GC-MS) was utilized to characterize the chemical constituents of RO. The antibacterial activity of RO was assessed using minimal inhibitory concentration(MIC) and time-kill assays. Various biochemical assays were employed to uncover the potential bactericidal mechanisms. Additionally, mouse and chick models of Salmonella infection were established to investigate the prophylactic effects of RO treatment. RO exhibited significant antibacterial activity against both Gram-positive and Gram-negative bacteria, with an MIC of 4 mg·mL^(-1) for Salmonella spp. RO treatment resulted in bacterial damage through the disruption of lipid and purine metabolism. Moreover, RO reduced injury and microbial colonization in infected mice and chicks. RO treatment also modulated the host inflammatory response by inhibiting proinflammatory pathways. In conclusion, our findings demonstrate that RO is effective against Salmonella infection, highlighting its potential as an alternative to antibiotics for antibacterial therapy.

关键词： Rosewood essential oil Salmonella Aniba rosaeodora Antibacterial effect Anti-inflammation Anti-infection