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Acute pancreatitis:Etiology and common pathogenesis

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World Journal of Gastroenterology 2009年第12期15卷 1427-1430页

作者： Guo-Jun wang chun-fang Gao Dong Wei Cun wang Si-Qin Ding Institute of Digestive Surgery and Department of General Surgery 150 Hospital of Chinese PLA Gaoxin District Luoyang 471031 Henan Province China

Acute pancreatitis is an inflammatory disease of the *** etiology and pathogenesis of acute pancreatitis have been intensively investigated for centuries *** causes of acute pancreatitis have been discovered,but the pathogenetic theories are *** most common cause of acute pancreatitis is gallstone impacting the distal common bile-pancreatic *** majority ofinvestigators accept that the main factors for acute billiary pancreatitis are pancreatic hyperstimulation and bile-pancreatic duct obstruction which increase pancreatic duct pressure and active trypsin *** pancreatitis occurs when intracellular protective mechanisms to prevent trypsinogen activation or reduce trypsin activity are ***,little is known about the other acute *** hypothesize that acute biliary pancreatitis and other causes of acute pancreatitis possess a common *** hyperstimulation and pancreatic duct obstruction increase pancreatic duct pressure,active trypsin reflux,and subsequent unregulated activation of trypsin within pancreatic acinar *** activation within the pancreas leads to auto-digestion of the gland and local *** the hypothesis is confirmed,traditional therapeutic strategies against acute pancreatitis may be *** of pancreatic duct pressure should be advocated in the treatment of acute pancreatitits which may greatly improve its outcome.

关键词： Acute pancreatitis Pathogenesis Etiology Pancreatic duct obstruction Pancreatichyperstimulation Pancreatic duct pressure

腓骨固定在胫腓骨关节外骨折中治疗效果的Meta分析

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中国骨伤 2024年第1期37卷 74-80页

作者：丛琳琳蒋品品郭华汪航车先达王春芳李文晋李鹏翠山西医科大学基础医学院生物化学与分子生物学教研室山西太原030001 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室山西太原030001 山西医科大学第二医院骨科山西太原030001 山西医科大学山西太原030001 山西医科大学实验动物中心山西太原030001 山西医科大学第二临床医学院口腔科山西太原030001

目的:通过Meta分析比较腓骨固定在胫腓骨关节外骨折中的作用及重要性。方法:通过对中国知网、维普、万方、The Cochrane Library、Web of science、Pubmed等数据库关于固定腓骨与否对胫腓骨关节外骨折治疗疗效比较的相关文献进行检索,... 详细信息

目的:通过Meta分析比较腓骨固定在胫腓骨关节外骨折中的作用及重要性。方法:通过对中国知网、维普、万方、The Cochrane Library、Web of science、Pubmed等数据库关于固定腓骨与否对胫腓骨关节外骨折治疗疗效比较的相关文献进行检索,检索时间为2012年1月至2022年2月,使用RevMan 5.3软件进行统计分析。对腓骨固定组与不固定组的复位不良率、旋转畸形率、内翻或外翻畸形率、前或后发畸形率、不愈合率、术后感染率、二次手术率及手术时间进行比较。结果:共纳入11篇文献,6篇随机对照研究和5篇病例对照研究,有8篇为高质量文献,共813例患者,其中腓骨固定治疗383例,未固定腓骨430例。Meta分析结果显示,与未固定腓骨相比,治疗胫腓骨关节外骨折时固定腓骨可以降低术后旋转畸形率[RR=0.22,95%CI(0.10,0.45),P0.05)。结论:在治疗胫腓骨关节外骨折时腓骨固定组相较于不固定组在防止旋转畸形和内翻或外翻畸形以及促进愈合方面更具优势。

关键词：胫骨腓骨骨折固定 Meta分析

Beam Splitting in Induced Inhomogeneous Media

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Chinese Physics Letters 2012年第6期29卷 155-158页

作者： wang chun-fang BAI Yan-Feng GUO Hong-Ju CHENG Jing College of Science University of Shanghai for Science and TechnologyShanghai 200093 Department of Physics Southeast UniversityNanjing 211189 Shanghai Publishing and Printing College Shanghai 200093 School of Physical Science and Technology South China University of TechnologyGuangzhou 510640

We study the spatial behavior of a deflected beam in a coherent A-type three-level atomic medium with an inhomogeneous control *** the Rabi coupling by the control laser is in a Gaussian profile,the spatialdependent refraction index of the atomic medium will result in a beam splitting as well as the deflection of the slow probe light under electromagnetically induced *** terms of the phase difference between the two splitting beams and the position of the splitting,the possible interpretation of the splitting is given in theory.

关键词： theory splitting beam

Unraveling the incompatibility mechanism of ethylene carbonate-based electrolytes in sodium metal anodes

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Journal of Energy Chemistry 2024年第7期94卷 560-567页

作者： Daomin Qin fangyuan Cheng Meilian Cao Feiyang Yan Qian wang chun fang Jiantao Han State Key Laboratory of Material Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan430074HubeiChina

Ethylene carbonate(EC)is widely used in lithium-ion batteries due to its optimal overall performance with satisfactory conductivity,relatively stable solid electrolyte interphase(SEI),and wide electrochemical *** is also the most widely used electrolyte solvent in sodium ion ***,compared to lithium metal,sodium metal(Na)shows higher activity and reacts violently with EC-based electrolyte(NaPF_(6)as solute),which leads to the failure of sodium metal batteries(SMBs).Herein,we reveal the electrochemical instability mechanism of EC on sodium metal battery,and find that the com-bination of EC and NaPF_(6) is electrically reduced in sodium metal anode during charging,resulting in the reduction of the first coulombic efficiency,and the continuous consumption of electrolyte leads to the cell *** address the above issues,an additive modified linear carbonate-based electrolyte is provided as a substitute for EC based ***,ethyl methyl carbonate(EMC)and dimethyl carbon-ate(DMC)as solvents and fluoroethylene carbonate(FEC)as SEI-forming additive have been identified as the optimal solvent for NaFP_(6)based electrolyte and used in Na_(4)Fe_(3)(PO_(4))_(2)(P_(2)O_(7))/Na *** batter-ies exhibit excellent capacity retention rate of about 80%over 1000 cycles at a cut-off voltage of 4.3 V.

关键词： Na metal batteries Ethylene carbonate decomposition Na_(4)Fe_(3)(PO_(4))_(2)(P_(2)O_(7))cathode Interface engineering Ethylene carbonate-free electrolyte

Constructing highly safe and long-life calcium ion batteries based on hydratedvanadium oxide cathodes featuring a pillar structure

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Rare Metals 2024年第6期43卷 2597-2612页

作者： chun-fang wang Shi-Wei Zhang Lan Huang Yuan-Min Zhu Feng Liu Jian-Chuan wang Li-Ming Tan chun-Yi Zhi Cui-Ping Han Powder Metallurgy Research Institute Central South UniversityChangsha410083China Songshan Lake Materials Laboratory Dongguan 523808China Research Institute of Interdisciplinary Science and School of Materials Science and Engineering Dongguan University of TechnologyDongguan 523808China Department of Materials Science and Engineering City University of Hong KongHong Kong 999077China Faculty of Materials Science and Energy Engineering/Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Calcium-ion batteries(CIBs)have generated intense interest due to the growing demand for safer,cheaper,and large-scale energy storage ***,their development is still in its infancy,owing to the lack of suitable cathodes for sustaining reversiblc Ca^(2+)intercalation/***,layered H_(2)V_(3)O_(8)(HVO)with Zn^(2+)pre-insertion(ZHVO)is reported as a high-rate and highly durable cathode material for *** existence of Zn^(2+)and H_(2)O pillars could expand the interlayer spacing up to 1.8 nm,which is favorable for the diffusion of bulky Ca^(2+).The formation of Zn-O bonds facilitates electron transfer and enhances electrical ***,the ZHVO cathode achieves superior capacity performance(213.9 mAh·g^(-1)at 0.2 A·g^(-1))and long lifespan(78.3%for 1,000 cycles at 5 A·g^(-1))compared to pristine *** functional theory(DFT)calculations revealed that Zn^(2+)moved during Ca^(2+)intercalation,thereby reducing the diffusion energy barrier and facilitating Ca^(2+)***,a safe aqueous calcium ion cell was successfully assembled.

关键词： Multivalent batteries Calcium-ion batteries Layered structure Vanadium oxide Cathode materials

Planning an adaptive reuse development of underutilized urban underground infrastructures:A case study of Qingdao,China

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Underground Space 2024年第1期14卷 18-33页

作者： Yong-Kang Qiao fang-Le Peng Yun-Hao Dong chun-fang Lu Research Center for Underground Space&Department of Geotechnical Engineering Tongji UniversityShanghai 200092China

Urban underground infrastructures(UUIs)are a vital component of built capital for urban ***,many cities are now home to a multitude of disused or underutilized UUIs,not least aged purpose-built underground facilities,causing a waste of valuable underground space resource *** the process of urban renewal,adaptive reuse can be an attractive solution to breathe new life into underutilized UUIs,while addressing some of the modern problems of the built environment by an economically feasible ***,there is a prevalent absence in the current literature of the overarching planning and decision-making approaches for an adaptive reuse development of underutilized *** the intention of addressing this shortfall,this paper first lays out development strategies,then sets the generic patterns for adaptive reuse of disused or underutilized *** the city of Qingdao,China as a case study,detailed planning and decision-making approaches with the aid of multi-source data and spatial analysis tools are *** is anticipated that the findings of this research will assist the adaptive reuse development of UUIs in providing theoretical guidance and empirical evidence,thereby enhancing the role of urban underground space use in contributing to urban revitalization and urban sustainability.

关键词： Urban underground infrastructures Underutilized Adaptive reuse Planning Urban renewal

No Incidence of Liver Cancer Was Observed in A Retrospective Studyof Patients with Aristolochic Acid Nephropathy

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Chinese Journal of Integrative Medicine 2024年第2期30卷 99-106页

作者： SU Tao fang Zhi-e GUO Yu-ming wang chun-yu wang Jia-bo JI Dong BAI Zhao-fang YANG Li XiAO Xiao-he Renal Division Department of MedicinePeking University First HospitalBeijing(100034)China Department of Pharmacy Chongqing Hospital of Traditional Chinese MedicineChongqing(400021)China Department of Hepatology Fifth Medical Center of Chinese PLA General HospitalBeijing(100039)China China Military Institute of Chinese Materia Fifth Medical Center of Chinese PLA General HospitalBeijing(100039)China Phase I Clinical Trials Unit Department of Medicine for Infectious DiseasesFifth Medical Center of Chinese PLA General HospitalBeijing(100039)China Department of Pharmacy Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan(250000)China National Key Laboratory of Kidney Diseases Beijing(100039)China

Objective:To assess the risk of aristolochic acid(AA)-associated cancer in patients with AA nephropathy(AAN).Methods:A retrospective study was conducted on patients diagnosed with AAN at Peking University First Hospital from January 1997 to December ***-term surveillance and follow-up data were analyzed to investigate the influence of different factors on the prevalence of *** primary endpoint was the incidence of liver cancer,and the secondary endpoint was the incidence of urinary cancer during 1 year after taking AA-containing medication to ***:A total of 337 patients diagnosed with AAN were included in this *** the initiation of taking AA to the termination of follow-up,39 patients were diagnosed with *** cases of liver cancer were observed throughout the entire follow-up period,with urinary cancer being the predominant type(34/39,87.17%).Logistic regression analysis showed that age,follow-up period,and diabetes were potential risk factors,however,the dosage of the drug was not significantly associated with urinary ***:No cases of liver cancer were observed at the end of ***,a high prevalence of urinary cancer was observed in AAN *** a direct causality between AA and HCC is challenging.

关键词： aristolochic acid hepatocellular carcinoma urinary cancer drug safety retrospective study

Anatomy of the lateral ligaments of the rectum: A controversial point of view

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World Journal of Gastroenterology 2010年第43期16卷 5411-5415页

作者： Guo-Jun wang, chun-fang Gao, Dong Wei, Cun wang, Wen-Jian Meng, Institute of Digestive Surgery and Department of General Surgery, 150 Hospital of PLA, Gaoxin District, Luoyang 471031, Henan Province, China Institute of Digestive Surgery and Department of General Surgery 150 Hospital of PLA Gaoxin District Luoyang 471031 Henan Province China. cchunfang@***

The existence and composition of the lateral ligaments of the rectum (LLR) are still the subjects of anatomical confusion and surgical misconception up to now. Since Miles proposed abdominoperineal excision as radical surgery for rectal cancer, the identification by "hooking them on the finger" has been accepted by many surgeons with no doubt; clamping, dividing and ligating are considered to be essential procedures in mobilization of the rectum in many surgical textbooks. But in cadaveric studies, many anatomists could not find LLR described by the textbooks, and more and more surgeons also failed to find LLR during the proctectomy according to the principle of total mesorectal excision. The anatomy of LLR has diverse descriptions in literatures. According to our clinical observations, the traditional anatomical structures of LLR do exist; LLR are constant dense connective bundles which are located in either lateral side of the lower part of the rectum, run between rectal visceral fascia and pelvic parietal fascia above the levator ani, and covered by superior fascia of pelvic diaphragm. They are pathways of blood vessels and nerve fibers toward the rectum and lymphatic vessels from the lower rectum toward the iliac lymph nodes.

关键词： The lateral ligaments of the rectum Anatomy Total mesorectal excision Abdominoperineal excision Fascia

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铁道行业专利标准化现状及策略研究

铁道工程学报 2016年第12期33卷 120-125页

作者：王春芳中铁第四勘察设计院集团有限公司武汉430063

研究目的:随着科学技术的快速发展和经济全球化进程的加快,企业竞争已经由产品竞争发展到专利和标准的竞争。由于标准必要专利承载着标准的普适性、权威性和专利的先进性、垄断性等特征,已经成为企业进行技术垄断和市场竞争的新手段。... 详细信息

研究目的:随着科学技术的快速发展和经济全球化进程的加快,企业竞争已经由产品竞争发展到专利和标准的竞争。由于标准必要专利承载着标准的普适性、权威性和专利的先进性、垄断性等特征,已经成为企业进行技术垄断和市场竞争的新手段。本文在分析铁道建筑行业专利与标准的特点、专利与标准发展现状的基础上,提出铁道行业专利标准化策略,对我国铁道行业工程建设标准的制(修)订和铁路"走出去"战略的实施具有一定的借鉴和参考作用。研究结论:(1)当前铁道建筑行业专利标准化进程缓慢,仅有少量标准必要专利;(2)实现专利标准化,是国家战略、技术发展和经济价值体现的需求;(3)推进专利标准化,必须在研究分析行业技术发展和市场前景的基础上,以企业的创新平台为基础、以技术创新为支撑、以产业知识产权联盟为纽带,在全面构建核心技术专利池的基础上,以专利标准化为目标,加强专利布局,推动核心专利纳入企业标准或团体标准,并逐步上升到行业标准或国家标准;(4)"技术-专利-标准"一体化的工作策略,对构建我国铁道建筑行业的专利运营体系具有指导意义,对推动我国创新驱动发展,促进企业转型升级,以及国家"一带一路"战略实施具有重要意义。

关键词：铁道工程建设专利标准化创新