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Journal of Iron and Steel Research International 2024年第1期31卷 215-223页

作者： Cheng Lu wan-lin wang Chen-yang Zhu Jie Zeng Xin-yuan Liu Hua-long Li School of Metallurgy and Environment Central South UniversityChangsha410083HunanChina National Center for International Research of Clean Metallurgy Central South UniversityChangsha410083HunanChina Institute of Research of Iron and Steel ShasteelZhangjiagang215625JiangsuChina

Typical Q235 low-carbon steel samples with different hydrogen contents(0.0004,0.0008,and 0.0013 wt.%)were prepared by adjusting the environment humidity and *** effects of hydrogen on interfacial heat transfer,contact behavior,and microstructure evolution were investigated using a novel droplet solidification *** results revealed that when the hydrogen content increases from 0.0004 to 0.0013 wt.%,the maximum heat flux between the molten steel and cooling substrate decreases from 8.01 to 6.19 MW/m^(2),and the total heat removed in the initial 2 s reduces from 10.30 to 8.27 MJ/m^(2).Moreover,the final contact angle between the molten steel and substrate increases from 103.741°to 113.697°,and the number of pores on the droplet bottom surface increases significantly from 21 to 210 with the increase in *** surface roughness of the droplet bottom surface increases from 20.902 to 49.181 *** addition,the average grain size of the droplet increases from 14.778 to 33.548 pm with the increase in the hydrogen *** interfacial contact condition becomes worse due to the escape of hydrogen from the steel matrix during the cooling process,which leads to the reduction in the interfacial heat transfer and the increase in the grain size.

关键词： Strip casting Hydrogen content Interfacial heat transfer behavior Contact behavior Microstructure evolution

RIOK1 synergizes with TRIP13 by regulating the E2F-Rb signaling pathway to promote the proliferation of esophageal cancer cells

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Genes & Diseases 2024年第3期11卷 55-58页

作者： Chengyu Li Deyuan Pan wan lin Danxia Deng Yingxin Zhou Hui Zhao Feng Pan Liyan Xu Enmin Li lin Long The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area Department of Biochemistry and Molecular BiologyShantou University Medical CollegeShantouGuangdong 515041China Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology Institute of Oncologic PathologyShantou University Medical CollegeShantouGuangdong 515041China Institute of Basic Medical Science Cancer Research CenterShantou University Medical CollegeShantouGuangdong 515041China Clinical Research Center Shantou Central HospitalShantouGuangdong 515041China

Esophageal cancer is one of the leading causes of cancer death in the world,with approximately half of the new cases occurring in China every year.^(1)Esophageal squamous cell carcinoma(ESCC)is the main subtype,accounting for more than 90%,and the five-year survival rate is less than 10%.Using large-scale genome analysis,many driver mutations and key pathways associated with ESCC have been ***,these genomic signatures have not improved the clinical management of EscC patients,or established effective targeted therapy.^(2)Esophageal cancer still lacks representative molecular markers.

关键词： cancer esophageal Esophageal

Large Deviations for a Critical Galton-Watson Branching Process

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Acta Mathematicae Applicatae Sinica 2024年

作者： Dou-dou LI wan-lin SHI Mei ZHANG College of Statistics and Data Science Faculty of Science Beijing University of Technology Laboratory of Mathematics and Complex Systems (Ministry of Education) School of Mathematical SciencesBeijing Normal University Department of Mathematics and Physics North China Electric Power University

In this paper, a critical Galton-Watson branching process{Zn}is considered. Large deviation rates of SZn:=∑i=1ZnXiare obtained, where{Xi, i≥1}is a sequence of independent and identically distributed random variables and X1is in the domain of attraction of an α-stable law with α∈(0, 2). One shall see that the convergence rate is determined by the tail index of X1and the variance of Z1. Our results can be compared with those ones of the supercritical case.

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Sirolimus can promote the disappearance of renal angiomyolipoma associated with tuberous sclerosis complex:a prospective cohort study

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World Journal of Pediatrics 2024年第6期20卷 602-610页

作者： Shuo Dun Yang-Yang wang lin wan Qiu-Hong wang Qian Lu Xiao-Yan Yang Qi Zhang Hui-Min Chen Lu-Peng Qiu Li-Ping Zou Medical School of Chinese PLA Beijing 100853China Department of Pediatrics The First Medical CenterChinese PLA General HospitalBeijing 100853China Center of Epilepsy Beijing Institute for Brain DisordersBeijing 100069China

Background Renal angiomyolipoma(RAML)is the most common kidney lesion in patients with tuberous sclerosis complex(TSC),affecting about 80%of *** is a benign tumor that grows over time,usually bilaterally,and can easily lead to kidney complications such as acute ***,we investigated the efficacy and safety of sirolimus in children with TSC-associated RAML and explored the factors affecting tumor disappearance under sirolimus treatment through subgroup *** A prospective cohort study was *** was initiated at 1 mg/(m^(2)×day),and dose adjustments were made by a 2-week titration period to attain a trough blood concentration of 5-10 ng/*** disappearance of RAML in chil-dren after sirolimus treatment was observed,and Cox regression was used to screen the factors affecting tumor *** One hundred and twenty-six patients who met the criteria were *** 3 months,6 months,12 months,and 24 months of follow-up,tumors disappeared in 18(14.3%),30(23.8%),39(31.0%),and 42(33.3%)children,*** disappeared in 50(39.7%)children by the last visit of each individual,and 30(60%)of them occurred within 6 *** multivariate Cox regression analysis showed that patients with a smaller maximum tumor diameter at baseline had a higher tumor disappearance ***-six(29%)patients had stomatitis during the entire treatment period,and no serious *** Sirolimus could promote the disappearance of TSC-related *** disappearance rate was correlated with the maximum diameter at baseline,and the smaller the tumor was,the higher the disappearance *** is well tolerated in the treatment of RAML associated with TSC.

关键词： Angiomyolipoma mTOR inhibitor Sirolimus Tuberous sclerosis

基于矩阵乘积压缩态的动态可扩展秘密共享方案

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物理学报 2024年第18期73卷 24-37页

作者：赖红万林春西南大学计算机与信息科学学院重庆400715

目前,基于纠缠态的量子秘密共享(quantum secret sharing,QSS)方案未充分利用纠缠态的概率振幅潜力.然而,纠缠态的概率振幅是量子信息学的一个关键特性,在量子计算和量子通信等领域有着广泛的应用潜力.值得注意的是,纠缠态可以通过矩阵... 详细信息

目前,基于纠缠态的量子秘密共享(quantum secret sharing,QSS)方案未充分利用纠缠态的概率振幅潜力.然而,纠缠态的概率振幅是量子信息学的一个关键特性,在量子计算和量子通信等领域有着广泛的应用潜力.值得注意的是,纠缠态可以通过矩阵乘积态(matrix product state,MPS)有效表达.利用MPS对纠缠态进行表征,能够准确地揭示与概率振幅相关的纠缠特性.本研究证明利用MPS表征纠缠态,可以将一个W态压缩为一个单光子和一个矩阵,展示一种新的技术路径.此外,本研究还提出MPS与秘密共享方案之间的创新互操作性,即通过压缩允许量子份额与共享的量子态之间形成非一对一的映射关系.这种方法可能提供一种更高效的方式来实现量子信息的编码和传输,对于量子秘密共享尤为重要.同时,我们提出的QSS方案具有动态特性,能够根据需要轻松地添加或移除参与者,以更好地适应参与者需求的变化,并在实际应用场景中展现出更高的实用性和适应性.本文的方案能够在保持高效纠缠利用的同时,满足系统的多元需求,包括但不限于通信安全性、数据传输率和系统的可扩展性.

关键词：矩阵乘积压缩态纠缠态的概率振幅可扩展性动态性

大学生运动身份认同对运动行为的影响:有调节的中介模型

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中国临床心理学杂志 2024年第2期32卷 463-468,415页

作者：任怡霖李宛霖朱风书扬州大学体育学院扬州225127

目的:探讨大学生运动身份认同与运动行为的关系,重点关注内部动机的中介作用,以及体重认知偏差的调节作用。方法:采用体育运动等级量表、运动依赖量表、运动身份认同量表、内部动机量表以及体重认知偏差问卷,对江苏省某高校950名在校大... 详细信息

目的:探讨大学生运动身份认同与运动行为的关系,重点关注内部动机的中介作用,以及体重认知偏差的调节作用。方法:采用体育运动等级量表、运动依赖量表、运动身份认同量表、内部动机量表以及体重认知偏差问卷,对江苏省某高校950名在校大学生进行调查,剔除59份无效问卷,最终获得有效问卷891份。结果:(1)大学生运动身份认同与适应性及适应不良运动行为呈正相关;(2)内部动机在大学生运动身份认同与适应性及适应不良运动行为之间起部分中介作用。体重认知偏差在运动身份认同和内部动机与运动行为(适应性及适应不良运动行为)关系间起调节作用。结论:运动身份认同不仅直接影响大学生运动行为,还可以通过内部动机间接地影响其运动行为。体重认知偏差调节大学生运动身份认同和内部动机与运动行为的关系。

关键词：运动身份认同体重认知偏差内部动机运动行为

Identification and validation of a pyroptosis-related prognostic model for colorectal cancer based on bulk and single-cell RNA sequencing data

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World Journal of Clinical Oncology 2024年第2期15卷 329-355页

作者： Li-Hua Zhu Jun Yang Yun-Fei Zhang Li Yan wan-Rong lin Wei-Qing Liu Department of Surgical Oncology The First Affiliated Hospital of Kunming Medical UniversityKunming 650032Yunnan ProvinceChina Department of Internal Medicine-Oncology The First Affiliated Hospital of Kunming Medical UniversityKunming 650032Yunnan ProvinceChina Department of Oncology The First Affiliated Hospital of Kunming Medical UniversityKunming 650032Yunnan ProvinceChina

BACKGROUND Pyroptosis impacts the development of malignant tumors,yet its role in colorectal cancer(CRC)prognosis remains *** To assess the prognostic significance of pyroptosis-related genes and their association with CRC immune *** Gene expression data were obtained from The Cancer Genome Atlas(TCGA)and single-cell RNA sequencing dataset GSE178341 from the Gene Expression Omnibus(GEO).Pyroptosis-related gene expression in cell clusters was analyzed,and enrichment analysis was conducted.A pyroptosis-related risk model was developed using the LASSO regression algorithm,with prediction accuracy assessed through K-M and receiver operating characteristic analyses.A nomo-gram predicting survival was created,and the correlation between the risk model and immune infiltration was analyzed using CIBERSORTx ***,the differential expression of the 8 prognostic genes between CRC and normal samples was verified by analyzing TCGA-COADREAD data from the UCSC *** An effective pyroptosis-related risk model was constructed using 8 genes-CHMP2B,SDHB,BST2,UBE2D2,GJA1,AIM2,PDCD6IP,and SEZ6L2(P<0.05).Seven of these genes exhibited differential expression between CRC and normal samples based on TCGA database analysis(P<0.05).Patients with higher risk scores demonstrated increased death risk and reduced overall survival(P<0.05).Significant differences in immune infiltration were observed between low-and high-risk groups,correlating with pyroptosis-related gene *** We developed a pyroptosis-related prognostic model for CRC,affirming its correlation with immune *** model may prove useful for CRC prognostic evaluation.

关键词： Colorectal cancer Pyroptosis Single-cell RNA sequencing Immune infiltration Prognostic model

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延迟退休、生育率与内生增长

中央财经大学学报 2024年第8期 82-101页

作者：万春林张卫四川大学经济学院西南民族大学经济学院

人口老龄化加剧使延迟退休呼声不断。本文将延迟退休纳入内生增长理论模型框架中,综合考虑延迟退休的资本积累效应、技术进步效应和生育效应,分析强制延迟退休和弹性退休两种退休模式对经济增长的影响。研究发现:预期寿命延长对生育率... 详细信息

人口老龄化加剧使延迟退休呼声不断。本文将延迟退休纳入内生增长理论模型框架中,综合考虑延迟退休的资本积累效应、技术进步效应和生育效应,分析强制延迟退休和弹性退休两种退休模式对经济增长的影响。研究发现:预期寿命延长对生育率和经济增长具有抑制作用,但实施延迟退休政策能够抵消此负面作用,预期寿命延长会使老年人愿意提供更多工作时间;尽管延迟退休会使储蓄下降,但延迟退休对生育率和技术进步的正向作用超过了储蓄下降的负向作用,表明延迟退休有利于经济增长;弹性退休模式下的生育率和人均产出增长率均高于强制延迟退休对应数值,表明弹性退休模式更有利于促进生育率和经济增长。因此,建议中国应推行允许个人可以在一定年龄范围内自主选择退休年龄的弹性退休政策,这将有利于促进生育率回升和经济增长。本文在一定程度上丰富了延迟退休与经济增长的理论研究,并为实施弹性退休政策提供了理论借鉴。

关键词：人口老龄化弹性退休生育率内生增长技术进步

地理大数据揭示中国主要城市建成环境物质存量的空间格局

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Engineering 2024年第3期34卷 143-153页

作者： Zhou Huang Yi Bao Ruichang Mao Han wang Ganmin Yin lin wan Houji Qi Qiaoxuan Li Hongzhao Tang Qiance Liu linna Li Bailang Yu Qinghua Guo Yu Liu Huadong Guo Gang Liu Institute of Remote Sensing and Geographical Information Systems School of Earth and Space SciencesPeking UniversityBeijing 100871China International Research Center of Big Data for Sustainable Development Goals Beijing 100094China SDU Life Cycle Engineering Department of Green TechnologyUniversity of Southern DenmarkOdense 5230Denmark Department of Construction Management School of Civil EngineeringTsinghua UniversityBeijing 100084China School of Computer Science China University of GeosciencesWuhan 430074China School of Geographical Sciences East China Normal UniversityShanghai 200062China Land Satellite Remote Sensing Application Center Ministry of Natural ResourcesBeijing 100048China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China Department of Geography California State UniversityLong BeachCA 90840USA Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China College of Urban and Environmental Sciences Peking UniversityBeijing 100871China

The patterns of material accumulation in buildings and infrastructure accompanied by rapid urbanization offer an important,yet hitherto largely missing stock perspective for facilitating urban system engineering and informing urban resources,waste,and climate ***,our existing knowledge on the patterns of built environment stocks across and particularly within cities is limited,largely owing to the lack of sufficient high spatial resolution *** study leveraged multi-source big geodata,machine learning,and bottom-up stock accounting to characterize the built environment stocks of 50 cities in China at 500 m fine-grained *** per capita built environment stock of many cities(261 tonnes per capita on average)is close to that in western cities,despite considerable disparities across cities owing to their varying socioeconomic,geomorphology,and urban form *** is mainly owing to the construction boom and the building and infrastructure-driven economy of China in the past ***’s urban expansion tends to be more“vertical”(with high-rise buildings)than“horizontal”(with expanded road networks).It trades skylines for space,and reflects a concentration-dispersion-concentration pathway for spatialized built environment stocks development within cities in *** results shed light on future urbanization in developing cities,inform spatial planning,and support circular and low-carbon transitions in cities.

关键词： Urban system engineering Built environment stock Spatial pattern Urban sustainability Big geodata

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贵州织金寒武系戈仲伍组钉形类骨片化石研究

古生物学报 2024年第2期63卷 155-170页

作者：朱万林杨兴莲贵州大学资源与环境工程学院贵州省古生物研究中心贵阳550025 喀斯特地质资源与环境教育部重点实验室(贵州大学) 贵阳550025

钉形类(nail-shaped)骨片化石是华南寒武纪早期地层中常见的一类具矿化骨骼的小壳化石。本文系统研究了贵州织金戈仲伍剖面寒武系戈仲伍组的钉形类骨片化石,发现织金地区钉形类化石主要以织金钉类和疑似的寒武钉类为主,共4属9种。相较... 详细信息

钉形类(nail-shaped)骨片化石是华南寒武纪早期地层中常见的一类具矿化骨骼的小壳化石。本文系统研究了贵州织金戈仲伍剖面寒武系戈仲伍组的钉形类骨片化石,发现织金地区钉形类化石主要以织金钉类和疑似的寒武钉类为主,共4属9种。相较于前人研究,本文新发现了织金钉类:Zhijinites tumourifomis、***、***,和疑似的寒武钉类:?Deiradoclavus sp.、?Cambroclavus sp.。排除埋藏学假象后,分析了钉形类不同化石属种保存方式及形态结构,发现Zhijinites的多数种都存在盘体顶面凹陷结构,并且Zhijinites部分种的锥体内壁有收缩现象或具有十字交错纤维结构,这些发现能较好地揭示出Zhijinites各形态种间的相似性和差异性。分析钉形化石时空分布特点发现,目前钉形类骨片化石最早在织金地区有化石记录,之后在扬子地台内部辐射扩散,并几乎同时辐射扩散至邻近陆块。此外,本文讨论的疑似寒武钉类化石时代可下延至寒武纪幸运期,可能是目前该类化石在全球的最早记录,为探索寒武钉类化石的系统演化和地层学意义提供了新信息。

关键词：小壳化石织金钉类寒武钉类戈仲伍组寒武系贵州