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Traumatic optic neuropathy:a review of 24 patients

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International Journal of Ophthalmology(English edition) 2010年第2期3卷 175-178页

作者： Kok Foo Lee Nor Idahriani Muhd Nor Azhany Yaakub wan hazabbah wan hitam Department of Ophthalmology School of Medical SciencesUniversiti Sains MalaysiaHealth Campus16150 Kubang KerianKelantanMalaysia

AIMTo evaluate the clinical presentations of traumatic optic neuropathy and to assess the visual outcome of three groups of patients managed differently (conservative, intravenous corticosteroids only and combination ... 详细信息

关键词： traumatic optic neuropathy orbital fractures corticosteroids

Bilateral atypical optic neuritis associated with tuberculosis in an immunocompromised patient

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Asian Pacific Journal of Tropical Biomedicine 2012年第7期2卷 586-588页

作者： Juanarita Jaafar wan hazabbah wan hitam Raja Azmi Mohd Noor Department of Ophthalmology School of Medical SciencesHealth CampusUniversiti Sains Malaysia

A 27 year-old lady,presented with sudden loss of vision in the right eve tor a *** was followed In poor vision in the left eye alter 3 *** involved the whole entire visual field and was associated with pain on eye *** was diagnosed to have miliary tuberculosis and retroviral disease 4 months *** was started on anti-TB since then but defaulted highly active anti-retroviral therapy(HAART).On *** visual acuity was no perception of light in the right eye and 6/120(pinhole 3/60) in the lelt *** segment in both eyes was *** showed bilateral optic disc swelling with presence ot multiple foci of choroiditis in the peripheral *** vitreous and relinal vessels were *** radiography was *** scan of orbit and brain revealed bilateral enhancement of the optic nerve sheath that suggest the diagnosis of bilateral atypical optic *** patient was managed with infectious disease *** was started on HAART and anti-TB treatment was *** completed anti-TB treatment alter 9 months without any serious side *** follow up the visual acuity in both eyes was not *** showed resolving ol disc swelling and choroiditis following treatment.

关键词： Tuberculosis Optic neuritis Funduscopy

Open globe injury in Hospital Universiti Sains Malaysia- a 10-year review

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International Journal of Ophthalmology(English edition) 2014年第3期7卷 486-490页

作者： Madhusudhan A/L Paramananda Evelyn-Tai Li Min Zamri Noordin Adil Hussein wan-hazabbah wan hitam Department of Ophthalmology School of Medical SciencesHealth Campus Universiti Sains Malaysia Kubang KerianKelantan 16150 Malaysia Hospital Universiti Sains Malaysia Kubang KerianKelantan 16150 Malaysia

AIM:To identify the aetiology of open globe injuries at Hospital Universiti Sains Malaysia over a period of 10y and the prognostic factors for visual ***:Retrospective review of medical records of open globe injury cases that presented from January2000 to December *** of open globe injury was based on the Birmingham Eye Trauma Terminology(BETT).Records were obtained with hospital permission via the in-house electronic patient management system,and the case notes of all patients with a diagnosis of open globe injury were *** with prior ocular trauma,pre-existing ocular conditions affecting the visual acuity,contrast sensitivity,central vision or corneal thickness,as well as those with a history of previous intraocular or refractive surgery were *** of data was with SPSS *** logistic regression analysis was used to examine the association between prognostic factors and visual ***:This study involved 220 patients(n=222eyes).The most common place of injury was the home(51.8%),followed by the workplace(23.4%).Among children aged less than 16y of age,domestic-related injury was the predominant cause(54.6%),while in those aged 16y and above,occupational injuries were the most common cause(40.0%).Most eyes(76.5%)had an initial visual acuity worse than 3/60,and in half of these,the visual acuity *** visual outcome was found to be significantly associated with the initial visual acuity(P<0.005),posterior extent of wound(P<0.001),length of wound(P<0.001),presence of hyphaema(P<0.001)and presence of vitreous prolapse(P<0.005).CONCLUSION:The most common causes of open globe injury are domestic accidents and occupational *** prognostic factors for final visual outcome in patients with open globe injury are initial visual acuity,posterior extent and length of wound,presence of hyphaema and presence of vitreous *** of the factors predicting

关键词： eye injuries occupational injuries vision disability visual impairment accidents intraocular foreign body

Excellent outcome of primary Neisseria meningitidis keratoconjunctivitis

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Asian Pacific Journal of Tropical Biomedicine 2011年第5期1卷 419-420页

作者： Jakiyah Daud Siti Raihan Ishak Zakuan Zainy Deris wan hazabbah wan hitam Department of Ophthalmology School of Medical SciencesHealth CampusUniversiti Sains Malaysia Department of Medical Microbiology ParasitologySchool of Medical SciencesHealth CampusUniversiti Sains Malaysia Infection Control Hospital Epidemiology UnitHospital Universiti Sains MalaysiaHelath CampusUniversiti Sains Malaysia

Infectious conjunctivitis is a very common presentation to medical professional and ophthalmologist all over the *** its typically self-limiting and treatable in almost all of the cases,but we need to be aware of the rare and potentially life threatening if the cause is not promptly identified and treated *** our case report,we highlighted the rare case of Neisseria meningitidis as a primary cause of *** meningitidis is a rare etiology of keratoconjunctivitis and its ocular presentations are quite similar with other bacterial or viral *** infection may potentially fatal if systemic invasion occurred,however with immediate and proper treatment the outcome is *** diagnosis and proper antibiotic treatment are critical to prevent systemic spread of the *** health intervention is needed to prevent outbreak of the disease.

关键词： Neisseria meningitidis Keratoconjunctivitis

Orbital apex syndrome after tooth extraction in an immunocompromised patient

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International Journal of Ophthalmology(English edition) 2011年第1期4卷 112-114页

作者： Suresh Subramaniam Cheong Min Tet wan hazabbah wan hitam Adil Hussein Shamim Ahmed Khan Hillol Kanti Pal Zunaina Embong Department of Ophthalmology School of Medical SciencesUniversiti Sains MalaysiaHealth Campus Department of Ortorhinolaryngology School of Medical SciencesUniversiti Sains MalaysiaHealth Campus Department of Neurosciences School of Medical SciencesUniversiti Sains MalaysiaHealth Campus

A 60 year-old man presented with acute on set of left eye proptosis and ptosis. It was associated with poor vision, eye pain and restriction of eye movement of the same eye after 5 hours post left upper molar tooth extraction. The visual acuity in the left eye was hand movement. There was severe ptosis and proptosis of the left eye. The conjunctiva was chemotic with quite anterior chamber. The pupil was mid dilated and sluggished to light. The ocular movement was restricted in all directions. Fundoscopy of the left eye revealed features of central retinal artery occlusion with hyperaemic disc and subretinal exudates at posterior pole. The right eye appeared normal. Urgent MRI brain and orbit revealed severe left paranasal sinusitis with anterior displacement of the left globe and presence orbital abscess. Patient was managed with Otorhinolaryngology and Neurosurgery teams. He underwent emergency transnasal drainage of abscess. Histopathological examination of unhealthy sinus mucosa showed evidence of fungal infection. However, the culture and sensitivity result was inconclusive. Patient was treated with amphotericin B, ceftriaxone, amoxicillin clavulanate and metronidazole. Patient was detected to have high blood sugar level and was managed accordingly. The proptosis improved with treatment. However, his vision, ptosis and ophthalmoplegia remained static. Assessing the immunocompromised status is important for the management of patient presented as acute orbital apex syndrome to avoid fatal outcome.

关键词： orbital apex syndrome tooth extraction proptosis ptosis ophthalmoplegia

免疫功能正常少年患早期表现为复视的隐球菌脑膜炎1例(英文)

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国际眼科杂志 2010年第3期10卷 421-423页

作者： Yanti Muslikhan wan hazabbah wan hitam Siti Raihan Ishak Ibrahim Mohtar John Takaran 马来西亚理科大学医学院眼科马来西亚理科大学医学院神经科

目的:报告免疫力正常少年的隐球菌脑膜炎1例,早期表现为复视和双眼视力低下。方法:病例报告。结果:男,17岁,两眼视物模糊并复视3wk,伴随严重的搏动性头痛、恶心、呕吐及低热。经体格检查无发热及假性脑膜炎迹象。双眼视力为6/15并视野... 详细信息

目的:报告免疫力正常少年的隐球菌脑膜炎1例,早期表现为复视和双眼视力低下。方法:病例报告。结果:男,17岁,两眼视物模糊并复视3wk,伴随严重的搏动性头痛、恶心、呕吐及低热。经体格检查无发热及假性脑膜炎迹象。双眼视力为6/15并视野缩窄。双眼前段正常。眼外肌运动表明双侧第六神经麻痹。眼底检查显示双侧视盘充血和轻度隆起。CT扫描大脑正常,无颅内肿块或脑室异常。腰椎穿刺发现高开放压>300mmH2O。脑脊液显微镜下及培养均存在新型隐球菌。本例由神经医疗组联合处理。患者开始静脉注射两性霉素B和氟康唑,神经症状1wk后恢复,双眼视力提高到6/6,同时周边视野恢复。随着第六神经麻痹的康复双眼复视得到好转。结论:本例强调了隐球菌脑膜炎进展缓慢的性质。即使免疫功能正常,也不会存在明显的假性脑膜炎特征,复视可能是脑膜炎患者的早期表现之一。

关键词：隐球菌脑膜炎视乳头水肿双侧第六神经麻痹

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先天性颅神经异常支配综合征2例(英文)

国际眼科杂志 2011年第12期11卷 2070-2072页

作者： Chui Yin Chua wan hazabbah wan hitam Fazilawati Qamarruddin 马来西亚士拉央医院眼科马来西亚理科大学医学院眼科马来西亚吉兰丹

我们报告两例在我们医疗中心治疗的先天性颅神经异常支配综合征(congenital cranial dysinnervation disorders,CCDD)。其中1例是7岁的中国女孩,无内科疾病,其父母注意到从婴孩时起患者习惯性向一侧倾斜头部,并伴有"眼懒惰"。双眼视力... 详细信息

我们报告两例在我们医疗中心治疗的先天性颅神经异常支配综合征(congenital cranial dysinnervation disorders,CCDD)。其中1例是7岁的中国女孩,无内科疾病,其父母注意到从婴孩时起患者习惯性向一侧倾斜头部,并伴有"眼懒惰"。双眼视力为斯内伦视力表6/6,头向右倾斜。水平或垂直注视时双眼外展受限,试图内转向下看时伴眼球内陷。另1例是10岁的马来西亚男孩,无内科疾病,其父母注意到自出生该男孩就"眼球运动差"。双眼视力为6/6,脸向左转并且双眼上睑下垂。在所有注视方位上眼球运动均受限,强制转向试验阳性。两个病例初步诊断均为先天性眼外肌纤维化(congenital fibrosis of extraocularmuscle,CFEOM),后来第一个病例的诊断修订为双侧Duane综合征。虽然Duane综合征和CFEOM都包括在CCDD内,但两种疾病病理不同。CCDD的表现非常多变,然而,治疗往往是有限的,且手术结果不可预测。因此,仍然需要进行大量研究以更深入了解CCDD,改善其治疗和结局。

关键词：先天性颅神经异常支配综合征异常神经支配

Bilateral optic nerve infiltration in tuberculous meningitis: A diagnostic dilemma

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Journal of Acute Disease 2021年第2期10卷 87-90页

作者： Lim Thiam-Hou Ibrahim Mohtar wan hazabbah wan hitam Sanihah Abdul Halim Department of Ophthalmology and Visual Science School of Medical SciencesHealth CampusUniversiti Sains Malaysia16150 Kubang KerianKelantanMalaysia Hospital Universiti Sains Malaysia 16150 Kubang KerianKelantanMalaysia Department of Medicine School of Medical SciencesHealth CampusUniversiti Sains Malaysia16150 Kubang KerianKelantanMalaysia

Rationale:Tuberculous meningitis(TBM)is severe extrapulmonary tuberculosis that can cause poor outcomes without timely *** report a case of presumed TBM that presented solely ocular complaints without other neurological ***'s concerns:A 71-year-old man presented with a sudden central visual defect in both eyes for 10 *** showed bilateral hyperaemic swelling disc with ***:A diagnosis of presumptive TBM was made with Mantoux test reading 15 mm,elevated erythrocyte sedimentation rate,subdural effusion on CT scan,and high opening ***:Anti-tuberculous ***:Bilateral vision improved and optic discs swelling ***:Early recognition of TBM with optic nerve infiltration is crucial for prompt treatment that may lead to a good *** will facilitate the diagnosis when other investigations show a borderline result.

关键词： Tuberculous meningitis Infiltrative optic neuropathy Tuberculoma

Endogenous endophthalmitis secondary to melioidosis in paediatric patients: Case series and review article

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Journal of Acute Disease 2018年第6期7卷 234-240页

作者： Wendy Ong Chin Feng Wee Min Teh wan-hazabbah wan hitam Haslina Mohammad Ali Department of Ophthalmology School of Medical SciencesHealth CampusUniversiti Sains MalaysiaKubang Kerian16150KelantanMalaysia Hospital Universiti Sains Malaysia Kubang KerianKelantanMalaysia Hospital Sultanah Bahiyah Alor SetarKedahMalaysia

Endogenous endophthalmitis is a devastating infection of the eye which can lead to permanent blindness. We report two rare cases of paediatric endogenous endophthalmitis secondary to melioidosis with contrasting visual outcomes. Both patients presented with acute painful visual loss with poor vision on presentation after exposure to open water sources (swimming at two separate locations with waterfalls). Both were diagnosed to have melioidosis endogenous endophthalmitis based on the ocular features clinically and via positive melioidosis serology. They otherwise did not exhibit any symptoms and signs suggestive of systemic melioidosis infection. Even though the two children demonstrated severe ocular involvement, ocular culture from vitreous and aqueous sampling taken from one of the patients did not yield any positive results. No ocular sampling was taken from the other patient. After standard antimicrobial treatment, the first patient responded well with good visual recovery without requiring any surgical intervention for the endophthalmitis. In contrast, our second patient ended up with poor visual outcome despite undergoing multiple intravitreal antibiotic injections and early pars plana vitrectomy. This is because he developed extensive retinal detachment due to the aggressive ocular infection. The diagnosis of endogenous endophthalmitis due to ocular melioidosis remains challenging and requires a high index of suspicion in areas endemic for the causative organism. Early empirical antibiotic treatment should be initiated in suspicious cases, even though the treatment outcomes may vary greatly.

关键词： Ocular melioidosis Endogenous endophthalmitis Vitrectomy Intravitreal antibiotics