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Usage of topical insulin for the treatment of diabetic keratopathy,including corneal epithelial defects

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World Journal of Diabetes 2023年第6期14卷 930-938页

作者： Ching Yee Leong Ainal Adlin Naffi wan haslina wan abdul halim Mae-Lynn Catherine Bastion Department of Ophthalmology Universiti Kebangsaan Malaysia Medical CentreKuala Lumpur 56000Wilayah PersekutuanMalaysia

BACKGROUND Diabetic keratopathy(DK)occurs in 46%-64%of patients with diabetes and requires serious *** patients with diabetes,the healing of corneal epithelial defects or ulcers takes longer than in patients without *** is an effective factor in wound *** ability of systemic insulin to rapidly heal burn wounds has been reported for nearly a century,but only a few studies have been performed on the effects of topical insulin(TI)on the *** with TI is effective in treating *** To review clinical and experimental animal studies providing evidence for the efficacy of TI to heal corneal *** National and international databases,including PubMed and Scopus,were searched using relevant keywords,and additional manual searches were conducted to assess the effectiveness of TI application on corneal wound *** articles published from January 1,2000 to December 1,2022 were *** relevancy of the identified citations was checked against predetermined eligibility standards,and relevant articles were extracted and *** A total of eight articles were found relevant to be discussed in this review,including four animal studies and four clinical *** to the studies conducted,TI is effective for corneal re-epithelialization in patients with diabetes based on corneal wound size and healing *** Available animal and clinical studies have shown that TI promotes corneal wound healing by several *** use of TI was not associated with adverse effects in any of the published *** studies are needed to enhance our knowledge and understanding of TI in the healing of DK.

关键词： Diabetes mellitus Diabetic keratopathy Topical insulin Healing

On-treatment isolated superior ophthalmic vein thrombosis complicated with carotid cavernous fistula: a case report

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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1726-1728页

作者： Yee Lin Lo Kah Wei Ong Teck Chee Cheng wan haslina wan abdul halim Meng Hsien Yong Department of Ophthalmology Faculty of MedicineUniversiti Kebangsaan MalaysiaKuala Lumpur 56000Malaysia

Dear Editor, We are writing this letter to present a case of ontreatment isolated superior ophthalmic vein thrombosis(SOVT) that progressed to cavernous sinus thrombosis(CST) and further complicated with carotid cavernous fistula(CCF). SOVT is a rare but potentially lethal illness. It is normally presented with orbital congestion syndrome with proptosis, ophthalmoplegia, diplopia, and high intraocular pressure(IOP)[1]. Late detection of this disease can lead to devastating complications such as optic nerve compression。

关键词： such letter complicated

A review of extreme condition effects on solder joint reliability:Understanding failure mechanisms

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Defence Technology（防务技术） 2024年第11期41卷 134-158页

作者： Norliza Ismail wan Yusmawati wan Yusoff Azuraida Amat Nor Azlian abdul Manaf Nurazlin Ahmad Department of Physics Centre for Defence Foundation StudiesUniversiti Pertahanan Nasional MalaysiaKem Sungai BesiKuala Lumpur57000Malaysia Centre for Tropicalization(CENTROP) Defence Research InstituteUniversiti Pertahanan Nasional MalaysiaKem Sungai BesiKuala Lumpur57000Malaysia

Solder joint,crucial component in electronic systems,face significant challenges when exposed to extreme conditions during *** solder joint reliability involving microstructure and mechanical properties will be affected by extreme *** the behaviour of solder joints under extreme conditions is vital to determine the durability and reliability of solder *** review paper aims to comprehensively explore the underlying failure mechanism affecting solder joint reliability under extreme *** study covers an in-depth analysis of effect extreme temperature,mechanical stress,and radiation conditions towards solder *** of each condition to the microstructure including solder matrix and intermetallic compound layer,and mechanical properties such as fatigue,shear strength,creep,and hardness was thoroughly *** failure mechanisms were illustrated in graphical diagrams to ensure clarity and ***,the paper highlighted mitigation strategies that enhancing solder joint reliability under challenging operating *** findings offer valuable guidance for researchers,engineers,and practitioners involved in electronics,engineering,and related fields,fostering advancements in solder joint reliability and performance.

关键词： Solder joint Extreme condition Failure mechanism Defence and military Reliability

Mean Opinion Score Estimation for Mobile Broadband Networks Using Bayesian Networks

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Computers, Materials & Continua 2022年第9期72卷 4571-4587页

作者： Ayman A.El-Saleh abdulraqeb Alhammadi Ibraheem Shayea Azizul Azizan wan haslina Hassan College of Engineering A’Sharqiyah University(ASU)Ibra400Oman Communication Systems and Networks Research Lab Malaysia-Japan International Institute of TechnologyUniversiti Teknologi MalaysiaKuala Lumpur54100Malaysia Department of Electronics and Communication Engineering Faculty of Electrical and Electronics EngineeringIstanbul Technical University(ITU)Istanbul34467Turkey Advanced Informatics Department Razak Faculty of Technology and InformaticsUniversiti Teknologi MalaysiaKuala Lumpur54100Malaysia

Mobile broadband(MBB)networks are expanding rapidly to deliver higher data *** fifth-generation cellular network promises enhanced-MBB with high-speed data rates,low power connectivity,and ultralow latency video ***,existing cellular networks are unable to perform well due to high latency and low bandwidth,which degrades the performance of various *** a result,monitoring and evaluation of the performance of these network-supported services is *** network providers optimize and monitor their network performance to ensure the highest quality of service to their *** paper proposes a Bayesian model to estimate the minimum opinion score(MOS)of video streaming services for any particular cellular *** MOS is the most commonly used metric to assess the quality of *** proposed Bayesian model consists of several input data,namely,round-trip time,stalling load,and bite *** was examined and evaluated using several test data sizes with various performance *** results show the proposed Bayesian network achieved higher accuracy overall test data sizes than a neural *** proposed Bayesian network obtained a remarkable overall accuracy of 90.36%and outperformed the neural network.

关键词： Quality of experience quality of service bayesian networks minimum opinion score artificial intelligence prediction mobile broadband

A comprehensive review of radiation effects on solder alloys and solder joints

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Defence Technology（防务技术） 2024年第9期39卷 86-102页

作者： Norliza Ismail wan Yusmawati wan Yusoff Nor Azlian abdul Manaf Azuraida Amat Nurazlin Ahmad Emee Marina Salleh Department of Physics Centre for Defence Foundation StudiesUniversiti Pertahanan Nasional MalaysiaKem Sungai BesiKuala Lumpur 57000Malaysia Department of Mineral and Geoscience Malaysia Mineral Research CentreJalan Sultan Azlan ShahIpoh 31400PerakMalaysia

In the realm of military and defence applications, exposure to radiation significantly challenges the performance and reliability of solder alloys and joints in electronic systems. This comprehensive review examines radiation-induced effects on solder alloys and solder joints in terms of microstructure and mechanical properties. In this paper, we evaluate the existing literature, including experimental studies and fundamental theory, to provide a comprehensive overview of the behavior of solder materials under radiation. A review of the literature highlights key mechanisms that contribute to radiation-induced changes in the microstructure, such as the formation of intermetallic compounds, grain growth,micro-voids and micro-cracks. Radiation is explored as a factor influencing solder alloy hardness,strength, fatigue and ductility. Moreover, the review addresses the challenges and limitations inherent in studying the effects of radiation on solder materials and offers recommendations for future research. It is crucial to understand radiation-induced effects on solder performance to design robust and radiationresistant electronic systems. A review of radiation effects on solder materials and their applications in electronics serves as a valuable resource for researchers, engineers, and practitioners in that field.

关键词： Defence technology Solder alloy Solder joints Radiation-induced effect Microstructure Mechanical properties

Growth inhibitory response and ultrastructural modification of oral-associated candidal reference strains (ATCC) by Piper betle L. extract

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International Journal of Oral Science 2014年第1期6卷 15-21页

作者： Mohd-Al-Faisal Nordin wan Himratul-Aznita wan Harun Fathilah abdul Razak Md Yusoff Musa Department of Oral Biology and Biomedical Sciences Faculty of Dentistry University of Malaya Institute of Biological Sciences Faculty of ScienceUniversity of Malaya

Candida species have been associated with the emergence of strains resistant to selected antifungal agents. Plant products have been used traditionally as alternative medicine to ease mucosal fungal infections. This study aimed to investigate the effects of Piper betle extract on the growth profile and the ultrastructure of commonly isolated oral candidal cells. The major component of Po betle was identified using liquid chromatography-mass spectrophotometry （LC-MS/MS）. Seven ATCC control strains of Candida species were cultured in yeast peptone dextrose broth under four different growth environments：（i） in the absence of P. betle extract; and in the presence of P. beUeextract at respective concentrations of （ii） 1 ***-1; （iii） 3 ***-1; and （iv） 6 ***- 1 The growth inhibitory responses of the candidal cells were determined based on changes in the specific growth rates （μ）. Scanning electron microscopy （SEM） was used to observe any ultrastructural alterations in the candida colonies. LC-MS/MS was performed to validate the presence of bioactive compounds in the extract. Following treatment, it was observed that the p-values of the treated cells were significantly different than those of the untreated cells （P〈0.05）, indicating the fungistatic properties of the P. beUe extract. The candidal population was also reduced from an average of 13.44× 10^6 to 1.78×10^6 viable cell counts （CFU）.mL-1, SEM examination exhibited physical damage and considerable morphological alterations of the treated cells. The compound profile from LC-MS/MS indicated the presence of hydroxybenzoic acid, chavibetol and hydroxychavicol in P. betle extract. The effects of P. betle on candida cells could potentiate its antifungal activity.

关键词： antifungal activity Candida cell morphology growth inhibitory effect Piperbetle L.

Acid Blue 25 adsorption on base treated Shorea dasyphylla sawdust:Kinetic,isotherm,thermodynamic and spectroscopic analysis

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Journal of Environmental Sciences 2012年第2期24卷 261-268页

作者： Megat Ahmad Kamal Megat Hanafiah wan Saime wan Ngah Shahira Hilwani Zolkafly Lee Ching Teong Zafri Azran abdul Majid Department of Chemistry Faculty of Applied SciencesUniversiti Teknologi MARA School of Chemical Sciences Universiti Sains Malaysia Kulliyyah of Allied Health Sciences International Islamic University Malaysia

The potential of base treated Shorea dasyphylla（BTSD） sawdust for Acid Blue 25（AB 25） adsorption was investigated in a batch adsorption *** physiochemical parameters such as pH,stirring rate,dosage,concentration,contact time and temperature were *** adsorbent was characterized with Fourier transform infrared spectrophotometer,scanning electron microscope and Brunauer,Emmett and Teller *** optimum conditions for AB 25 adsorption were pH 2,stirring rate 500 r/min,adsorbent dosage 0.10 g and contact time 60 *** pseudo second-order model showed the best conformity to the kinetic *** equilibrium adsorption of AB 25 was described by Freundlich and Langmuir,with the latter found to agree well with the isotherm *** maximum monolayer adsorption capacity of BTSD was 24.39 mg/g at 300 K,estimated from the Langmuir *** parameters such as Gibbs free energy,enthalpy and entropy were *** was found that AB 25 adsorption was spontaneous and exothermic.

关键词： Acid Blue 25 adsorption Shorea dasyphylla sawdust spectroscopy thermodynamic

Conflict Resolution Strategy in Handover Management for 4G and 5G Networks

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Computers, Materials & Continua 2022年第9期72卷 5215-5232页

作者： abdulraqeb Alhammadi wan haslina Hassan Ayman A.El-Saleh Ibraheem Shayea Hafizal Mohamad Yousef Ibrahim Daradkeh Communication Systems and Networks Research Lab Malaysia-Japan International Institute of TechnologyUniversiti Teknologi Malaysia54100Kuala LumpurMalaysia College of Engineering A’sharqiyah University(ASU)Ibra400Oman Department of Electronics and Communication Engineering Faculty of Electrical and Electronics EngineeringIstanbul Technical University(ITU)Istanbul34467Turke Faculty of Engineering and Built Environment Universiti Sains Islam MalaysiaBandar Baru Nilai71800Malaysia Department of Computer Engineering and Networks College of Engineering at Wadi AddawasirPrince Sattam Bin Abdulaziz UniversityAl Kharj11991KSA

Fifth-generation(5G)cellular networks offer high transmission rates in dense urban ***,a massive deployment of small cells will be required to provide wide-area coverage,which leads to an increase in the number of handovers(HOs).Mobility management is an important issue that requires considerable attention in heterogeneous networks,where 5G ultra-dense small cells coexist with current fourth-generation(4G)*** mobility robustness optimization(MRO)and load balancing optimization(LBO)functions have been introduced in the 3GPP standard to address HO problems,non-robust and nonoptimal algorithms for selecting appropriate HO control parameters(HCPs)still exist,and an optimal solution is subjected to compromise between LBO and MRO ***,HO decision algorithms become *** paper proposes a conflict resolution technique to address the contradiction between MRO and LBO *** proposed technique exploits received signal reference power(RSRP),cell load and user speed to adapt HO margin(HM)and time to trigger(TTT).Estimated HM and TTT depend on a weighting function and HO type which is represented by user status during *** proposed technique is validated with other existing algorithms from the *** results demonstrate that the proposed technique outperforms existing algorithms overall performance *** proposed technique reduces the overall average HO ping-pong probability,HO failure rate and interruption time by more than 90%,46%and 58%,respectively,compared with the other schemes overall speed scenarios and simulation time.

关键词： Mobility management handover 5G heterogeneous networks

Catalytic methanation reaction over alumina supported cobalt oxide doped noble metal oxides for the purification of simulated natural gas

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燃料化学学报 2012年第7期40卷 822-830页

作者： wan Azelee wan Abu Bakar Rusmidah Alil abdul Aziz abdul Kadir Salmiah Jamal Mat Rosid Nurul Shafeeqa Mohammad Department of Chemistry Faculty of Science Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia Faculty of Petroleum and Renewable Energy Engineering Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia

A series of alumina supported cobalt oxide based catalysts doped with noble metals such as ruthenium and platinum were prepared by wet impregnation *** variables studied were difference ratio and calcination ***/Co(10∶90)/Al2O3 catalyst calcined at 700 ℃ was found to be the best catalyst which able to convert 70.10% of CO2 into methane with 47% of CH4 formation at maximum temperature studied of 400 ℃.X-ray diffraction analysis showed that this catalyst possessed the active site Co3O4 in face-centered cubic and PtO2 in the orthorhombic phase with Al2O3 existed in the cubic *** to the FESEM micrographs,both fresh and spent Pt/Co(10∶90)/Al2O3 catalysts displayed small particle size with undefined *** Adsorption analysis showed that 5.50% reduction of the total surface area for the spent Pt/Co(10∶90)/Al2O3 ***,Energy Dispersive X-ray analysis(EDX) indicated that Co and Pt were reduced by 0.74% and 0.14% respectively on the spent Pt/Co(10∶90)/*** using FT-IR and TGA-DTA analysis revealed the existence of residual nitrate and hydroxyl compounds on the Pt/Co(10∶90)/Al2O3 catalyst.

关键词： natural gas cobalt oxide noble metal catalyst methanation reaction