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Multidrug resistance Acinetobacter species at the intensive care unit,Aseer Central Hospital,Saudi Arabia:A one year analysis

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Asian Pacific Journal of Tropical Medicine 2016年第9期9卷 881-885页

作者： Ali Al Bshabshe Martin R.P.Joseph Ali Al Hussein waleed haimour Mohamed E.Hamid Department of Medicine College of MedicineKing Khalid University Department of Microbiology College of MedicineKing Khalid University Intensive Care Unit Aseer Central Hospital Microbiology Laboratories Aseer Central Hospital

Objective:To identify and to determine the antimicrobial susceptibility of Acinetobacter baumannii(***) clinical isolates from ICU at Aseer Central ***:The study was conducted in the Intensive Care Unit,Aseer Central Hospital,Saudi Arabia over 13 months period(2014-2015).Acinetobacter species(n= 105) were isolated from various clinical *** were identified using selected phenotypic criteria and confirmed using the Vitek 2 automated *** system was used to determine the susceptibilities of 21 antimicrobial ***,isolates and drug data were analyzed using the SPSS statistical software package to determine some epidemiological and microbiological ***:Of the 105 stains,*** accounted for 49(46.67%),*** complex,19(18.09%),***/haemolyticus 32(30.47),Acinetobacter haemolyticus 4(3.81%),Acinetobater lwoffii 1(0.95%) and unidentified Acinetobater species 2(1.3%).Of the 105 Acinetobacter strains,103(98.1%) were found multidrug resistant(MDR).*** strain were 100% sensitive to colistin and 74.5% to trimethoprim + *** remaining 19 antimicrobial agents revealed low or no sensitivities:amikacin 16.3%; ampicillin 7.7%; ceftazidime 7.3%.Distribution of similar sensitivities was shown by other Acinetobacter *** number of isolates from males and females indicates no statistical variation(P=0.867) whereas age groups showed significant differences(P= 0.008) as it is clear from the high percentage of infected individuals more than 60 years followed by those aged 20 to 29 years old(19.05%).Upper respiratory tract(30.48%),lower respiratory tract(47.65%) and subcutaneous tissue(9.5%) were the main sources of Acinetobacter *** mean numbers of isolates from these specimens indicate no discrepancy between specimens(P=0.731).Conclusions:Acinetobacterspecies including *** were found MDR(98.1%) according to the current Acinetobacter *** categorization.A

关键词： Acinetobacter spp. ICU Antimicrobials Aseer Central Hospital

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