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云南民族大学学报（自然科学版） 2022年第1期31卷 8-14页

作者：吕典冷露芬张琪王阿英赖祺易春蝶马燕华尹俊林曾广智云南民族大学民族医药学院民族药资源化学国家民委-教育部重点实验室云南昆明650500

从常山属植物硬毛常山中分离得到化合物(E)-6-(4-羟基苯基)庚-3-烯-2-酮(EHP),发现其具有较好的抑制人结直肠癌HCT-15细胞增殖活性.深入探究其抗肿瘤活性机理,发现其主要通过细胞周期阻滞,诱导HCT-15细胞的凋亡,抑制了人结直肠癌HCT-15... 详细信息

从常山属植物硬毛常山中分离得到化合物(E)-6-(4-羟基苯基)庚-3-烯-2-酮(EHP),发现其具有较好的抑制人结直肠癌HCT-15细胞增殖活性.深入探究其抗肿瘤活性机理,发现其主要通过细胞周期阻滞,诱导HCT-15细胞的凋亡,抑制了人结直肠癌HCT-15细胞增殖.采用SRB细胞活性检测法、台盼蓝染色、平板克隆实验、流式细胞仪、周期试剂盒检测、Western blot检测和Annexin-FITC/PI双染法,研究EHP抑制人结直肠癌HCT-15细胞增殖机理,发现EHP通过抑制P53、P27、P21、CDK4、Cyclin A2和Cyclin D1蛋白表达,促进蛋白CDK1、CDK2、Cyclin B1和Cyclin E1表达,阻滞肿瘤细胞停留在G2期,抑制了细胞的增殖;另外,EHP通过上调cleaved PARP1、active Caspase 9和active Caspase 3活性蛋白表达,诱导HCT-15凋亡作用.

关键词：硬毛常山增殖细胞周期凋亡

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Evidence of a J/ψΛstructure and observation of excited■^(-)states in the■b^(-)→J/ψΛK^(-) decay

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Science Bulletin 2021年第13期66卷 1278-1287,M0003页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back S.Baker P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista Leite R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bizzeti M.Bj┆rn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M.J.Bradley S.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo magalhaes A.Camboni P.Campana A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovská M.Cruz Torres R.Currie C.L.Da Silva E.Dall’ Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-ringuet(llr) PalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakówPoland AGH-University of Science and Techno

First evidence of a structure in the J/ψΛinvariant mass distribution is obtained from an amplitude analysis of■b^(-)J/ψΛK^(-)*** observed structure is consistent with being due to a charmonium pentaquark with strangeness with a significance of 3.1r including systematic uncertainties and lookelsewhere *** mass and width are determined to be 4458:8±2:9t4:7-1:1 MeV and 17:3±6:5t8:0-5:7 MeV,respectively,where the quoted uncertainties are statistical and *** structure is also consistent with being due to two *** addition,the narrow excited■^(-)states,N■(1690)and■(1820),are seen for the first time in a■b^(-)decay,and their masses and widths are measured with improved *** analysis is performed using pp collision data corresponding to a total integrated luminosity of 9 fb^(-1),collected with the LHCb experiment at centre-of-mass energies of 7,8 and 13 TeV.

关键词： QCD Exotics Pentaquark Spectroscopy Quarkonium Particle and resonance production

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Search for the doubly heavy baryons Ω^(0)_(bc) and E^(0)_(bc) decaying to Λ^(+)_(c)π^(-) and E^(+)_(c)π^(-)

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Chinese Physics C 2021年第9期45卷 10-21页

作者： R.Aaij C.Abelian Beteta T.Ackernley B.Adeva M.Adinolfi H.Afshamia C.A.Aidala S.Aiola Z.Ajaltouni S.Aka J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelie S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista Leite R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Beminghoff H.C.Bernstein C.Bertella A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bitadze A.Bizzeti M.Bjorn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M J.Bradley S.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo magalhaes A.Camboni P.Campana A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Camiti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovska M.Cruz Torres R.Currie C.L.Da Silva E.Dall'Occo J.Dalseno C.D'Ambrosi Centro Brasileiro de Pesquisas Fisicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina Institute of High Energy Physics(IHEP) BeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University ofChinese Academy of Sciences BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Savoie Mont Blanc CNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universite Paris-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-Ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance LPNHE Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/FN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany max-Planck-Institut für Kemphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma La Sapienza RomaItaly INFN Sezione di Roma Tor Vergata RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands AGH-University of Science and Technology Faculty of Physics and Applied Computer ScienceKr

The first search for the doubly heavyΩ^(0)_(bc)baryon and a search for the E^(0)_(bc)baryon are performed using pp collision data collected via the LHCb experiment from 2016 to 2018 at a centre-of-mass energy of 13 TeV,corresponding to an integrated luminosity of 5.2 fb^(-1).The baryons are reconstructed via their decays to Λ^(+)_(c)π^(-)and E^(+)_(c)π^(-).No significant excess is fbund for invariant masses between 6700 and 7300 MeV/c^(2),in a rapidity range from 2.0 to 4.5 and a transverse momentum range from 2 to 20 MeV/*** limits are set on the ratio of the Ω^(0)_(bc)and E^(0)_(bc)production cross-section times the branching fraction to Λ^(+)_(c)π^(-)(E^(+)_(c)π^(-))relative to that of the Λ^(0)_(b)(E^(0)_(b))baryon,for different lifetime hypotheses,at 95%confidence *** upper limits range from 0.5 x 10^(-4)to 2.5 x 10^(-4)for theΩ^(0)_(bc)→Λ^(+)_(c)π^(-)(E^(0)_(bc)→Λ^(+)_(c)π^(-))decay,and from 1.4x 10^(-3)to 6.9 x 10^(-3)for theΩ^(0)_(bc)→E^(+)_(c)π^(-)(E^(0)_(bc)→E^(+)_(c)π^(-))decay,depending on the considered mass and lifetime of theΩ^(0)_(bc)(E^(0)_(bc))baryon.

关键词： B physics quarkonium spectroscopy heavy quark production

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Search for the doubly heavy baryon Ξ_(bc)^(+)→ decaying to J/ψΞ_(c)^(+)

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中国物理C:英文版 2023年第9期47卷 1-13页

作者： R.Aaij A.S.W.Abdelmotteleb C.Abellan Beteta F.Abudinén T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.Agapopoulou C.A.Aidala S.Aiola Z.Ajaltouni S.Akar K.Akiba J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche P.Alvarez Cartelle S.Amato J.L.Amey Y.Amhis L.An L.Anderlini M.Andersson A.Andreianov M.Andreotti D.Andreou D.Ao F.Archilli A.Artamonov M.Artuso E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back A.Bailly-reyre P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista de Souza Leite M.Barbetti R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay A.Beck M.Becker F.Bedeschi I.B.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker N.V.Biesuz S.Bifani P.Billoir A.Biolchini M.Birch F.C.R.Bishop A.Bitadze A.Bizzeti M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev N.Bondar S.Borghi M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M.J.Bradley S.Braun A.Brea Rodriguez J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura L.Buonincontri A.T.Burke C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo magalhaes P.Campana D.H.Campora Perez A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus A.Casais Vidal R.Caspary G.Casse M.Cattaneo G.Cavallero V.Cavallini S.Celani J.Cerasoli D.Cervenkov A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.Chernyshenko V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek G.Ciullo P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina Institute Of High Energy Physics(IHEP) BeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Université Savoie Mont Blanc CNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-Ringuet CNRS/IN2P3Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universitàdegli Studi di Padova Universitàe INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma La Sapienza RomaItaly INFN Sezione di Roma Tor Vergata RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands AGH-University of Science and Technology Faculty of Physics and Applied Computer Scienc

A first search for the Ξ_(bc)^(+)J/ψΞ_(c)^(+) decay is performed by the LHCb experiment with a data sample of proton-proton collisions, corresponding to an integrated luminosity of 9 fb−1 recorded at centre-of-mass energies of 7, 8, and 13 TeV. Two peaking structures are seen with a local (global) significance of 4.3(2.8) and 4.1(2.4) standard deviations at masses of 6571 and 6694 MeV/c2, respectively. Upper limits are set on the Ξ+bc baryon production cross-section times the branching fraction relative to that of the B+c→J/ψD+s decay at centre-of-mass energies of 8 and 13 TeV, in the Ξ+bc and in the B+c rapidity and transverse-momentum ranges from 2.0 to 4.5 and 0 to 20GeV/c, respectively. Upper limits are presented as a function of the Ξ+bc mass and lifetime.

关键词： QCD B physics charm physics spectroscopy

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