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Marine Life Science & Technology 2021年第4期3卷 542-551页

作者： Zhen Wu Xiaohong Yang Senjie Lin wai hin lee Paul K.S.Lam State Key Laboratory of Marine Pollution City University of Hong KongHong KongChina Department of Chemistry City University of Hong KongHong KongChina State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361005China Department of Marine Sciences University of ConnecticutGrotonCT 06340USA Department of Biomedical Sciences City University of Hong KongHong KongChina Shenzhen Key Laboratory for the Sustainable Use of Marine Biodiversity Research Centre for the Oceans and Human HealthCity University of Hong Kong Shenzhen Research InstituteShenzhen 518057China

Rhizobium bacteria are known as symbionts of legumes for developing nodules on plant roots and fixing N2 for the host plants but unknown for associations with ***,we detected,isolated,and characterized a Rhizobium species from the marine toxic dinoflagellate Gambierdiscus *** 16S rRNA gene(rDNA)is 99%identical to that of Rhizobium rosettiformans,and the affiliation is supported by the phylogenetic placement of its cell wall hydrolase-encoding gene(cwh).Using quantitative PCR of 16S rDNA and cwh,we found that the abundance of this bacterium increased during the late exponential growth phase of Gambierdiscus and under nitrogen limitation,suggesting potential physiological interactions between the dinoflagellate and the *** is the first report of dinoflagellate-associated Rhizobium bacterium,and its prevalence and ecological roles in dinoflagellate-Rhizobium relationships remain to be investigated in the future.

关键词： Rhizobium Gambierdiscus 16S rRNA gene Cell wall hydrola Edited by Chengchao Chen

Dipyridyl Azo Compound 4,4'-Azopyridine as a Potential Coating Material for Toilet Sanitizer

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Chemical Research in Chinese Universities 2023年第6期39卷 864-869页

作者： WANG Qiwei JIANG Lu LAM Pik-Ling CHUI Chung-hin WONG wai-Yeung Antibiotics Research and Reevaluation Key Laboratory of Sichuan Province Sichuan Industrial Institute of AntibioticsChengdu UniversityChengdu 610052P.R.China Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHung HomHong KongP.R.China Research and Development Division One Health International LimitedHong KongP.R.China

Good toilet hygiene can reduce the risk of pathogenic *** flushing,pathogenic bacteria can be spread by the water droplets,especially in the toilet *** coli(***)is one of the frequently occurring Gram-negative bacterial pathogens found in the toilet *** this study,we investigated the potential *** activity of some azobenzene *** them,compound 2,with the heterocyclic nitrogen in both phenyl rings,showed the strongest antibacterial effect on ***,with the minimum inhibitory concentration of 80μg/mL and the minimum bactericidal concentration of 320μg/*** 2 displayed a comparative zone of clearance[(14.50±2.29)mm]to that of ampicillin[(13.17±1.76)mm].The reactive oxygen species(ROS)assay suggested that compound 2 might induce the loss of bacteria via the oxidative stress by eliciting the generation of intracellular *** further examined the potential cytotoxicity of compound 2 to the human skin HaCaT *** 2-treated skin cells showed a good maintenance of cellular morphology and a clear definition of cell nuclei,with a satisfactory cell viability(ca.90%)at 80μg/***,compound 2 would be a possible antibacterial coating agent for the surface sanitizer of the toilet seats to inhibit the growth of ***.

关键词： Antibacterial Azobenzene Escherichia coli Skin cytotoxicity Toilet seat

Organic Solar Cells at Stratospheric Condition for High Altitude Platform Station Application

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Chinese Journal of Chemistry 2022年第24期40卷 2927-2932页

作者： Ram Datt Harrison Ka hin lee Guichuan Zhang hin-Lap Yip Wing Chung Tsoi SPECIFIC Faculty of Science and EngineeringSwansea UniversityBay CampusFabian WaySwanseaSA18EN United Kingdom Department of Physics City University of Hong KongKowloonHong KongSARChina School of Semiconductor Science and Technology South China Normal UniversityFoshanGuangdong528225 China State Key Laboratory of Luminescent Materials and Devices South China University of Technology381 Wushan RoadGuangzhouGuangdong510640 China Department of Materials Science and Engineering City University of Hong KongKowloonHong KongChina School of Energy and Environment City University of Hong KongKowloonHong KongChina Hong Kong Institute for Clean Energy City University of Hong KongKowloonHong KongChina

High specific power or power to mass ratio is a critical concern of photovoltaic(PV)for aerospace *** solar cells(OSCs)have advantages such as high absorption coefficient,compatibility with flexible substrate,light-weight,***,recently OSCs achieved power conversion efficiency(PCE)over 20%with the incorporation of the non-fullerene based small molecule acceptor and high specific power is believed to be *** enter the market,high-altitude platform station(HAPS)is perhaps the first place to start *** this work,we explore and compare the in-situ performance of two high performing OSCs,using the same donor but different acceptors,in mimic HAPS environment where the pressure,temperature and the illumination conditions are *** found that the use of acceptor can result in substantial difference in the performance at low temperatures.

关键词： Organic solar cells Stratosphere High-altitude platform station Low-temperature physics Donor-acceptor systems

Prediction of salinity intrusion in the sheltered estuary of Terengganu River in Malaysia using 1-D empirical intrusion model

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Acta Oceanologica Sinica 2017年第5期36卷 57-66页

作者： lee hin lee TANGANG Fredolin GISEN Jacqueline Isabella SURATMAN Saim Research Centre for Tropical Climate Change Faculty of Science and TechnologyThe National University of MalaysiaUKM Bangi 43600Malaysia Research Centre for Water Quality and Environment National Hydraulic Research Institute of MalaysiaMinistry of Natural Resources and EnvironmentSeri Kembangan 43300Malaysia Centre for Earth Resources Research and Management Faculty of Civil Engineering and Earth ResourcesThe Universiti Malaysia PahangPahang 26600Malaysia

Generally one dimensional （l-D） empirical salinity intrusion model is limited to natural alluvial estuary. However, this study attempts to investigate its ability to model a sheltered alluvial estuary of the Terengganu River in Malaysia. The constructed breakwater at the mouth of the river shelters the estuary from direct influence of the open sea. The salinity density along the estuary was collected during the wet and dry seasons for scenarios before and after the constructed breakwater. Moreover, the freshwater discharges, tidal elevations and bathymetry data were also measured as model inputs. A good fit was demonstrated between simulated and observed variables, namely salinity distribution and intrusion length for both scenarios. Thus, the results show that 1-D empirical salinity model can be utilized for sheltered estuarine condition at the Terengganu Estuary, but with an appropriate determination of an initial point. Furthermore, it was observed that the salinity intrusion in the study area is largely dependent on the freshwater discharge rather than tidal elevation fluctuations. The scale of the salinity intrusion length in the study area is proportional to the river discharge of the -1/2 power. It was appeared that the two lines of the 1-D empirical salinity model and discharge power based equation fitted well to each other, with the average predicted minimum freshwater discharge of 150 m^3/s is going to be required to maintain acceptable salinity levels during high water slack （HWS） near the water intake station, which is located at 10.63 km from river mouth.

关键词： salinity intrusion sheltered estuary freshwater discharge geometric characteristic empirical model

Cryptococcal meningitis with pulmonary cryptococcoma in an immunocompetent patient: A case report

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Asian Pacific Journal of Tropical Medicine 2020年第1期13卷 46-48页

作者： Kee Tat lee Kar Ying Yong Hock hin Chua Department of Medicine Miri General HospitalSarawakMalaysia Infectious Disease Unit Department of MedicineSarawak General HospitalSarawakMalaysia

Rationale:Cryptococcal infections commonly occur in immunosuppressed patients and are uncommon in immunocompetent *** concerns:A 32 year old lady,active smoker presented with right chest pain,dry cough and loss of *** chest radiograph showed a lobulated lung mass in the right lower *** developed headache and right cranial nerve palsy during *** investigations were done including lumbar puncture,brain and chest ***:Cryptococcal meningitis with pulmonary ***:She received five months of effective antifungal treatment;however,the patient did not respond ***,removal of pulmonary cryptococcoma was ***:Her condition improved and she no longer had any ***:Disseminated cryptococcosis is rare in immunocompetent *** case highlights the importance of high index of suspicion and we postulate that lobectomy helped in reducing the cryptococcal burden in her body,thus facilitating better response to antifungal therapy.

关键词： Cryptococcoma Meningitis Immunocompetent Antifungal Lobectomy

Assessment of Pb uptake,translocation and immobilization in kenaf (Hibiscus cannabinus L.) for phytoremediation of sand tailings

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Journal of Environmental Sciences 2008年第11期20卷 1341-1347页

作者： HO wai Mun ANG Lai Hoe lee Don Koo Forest Research Institute Malaysia 52109 KepongSelangorMalaysia Department of Forest Sciences Seoul National UniversitySeoul 151-921Korea

The potential of kenaf (Hibiscus cannabinus L.) for phytoremediation of lead (Pb) on sand tailings was investigated.A pot experiment employing factorial design with two main effects of fertilizer and lead was conducted in a nursery using sand tailings from an ex-tin mine as the growing *** showed that Pb was found in the root,stem,and seed capsule of kenaf but not in the *** of organic fertilizer promoted greater biomass yield as well as higher accumulation capacity of *** Pb-spike...

关键词： kenaf lead fertilizer bioaccumulation capacity phytoremediation

Inhalation of nanoparticle-based drug for lung cancer treatment:Advantages and challenges

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Asian Journal of Pharmaceutical Sciences 2015年第6期10卷 481-489页

作者： Wing-hin lee Ching-Yee Loo Daniela Traini Paul M.Young Respiratory Technology Woolcock Institute of Medical Research and Discipline of PharmacologySydney Medical SchoolThe University of SydneyNSW 2037Australia

Ever since the success of developing inhalable insulin,drug delivery via pulmonary administration has become an attractive route to treat chronic *** delivery system for nanotechnology is a relatively new concept especially when applicable to lung cancer ***-based systems such as liposome,polymeric nanoparticles or micelles are strategically designed to enhance the therapeutic index of anti-cancer drugs through improvement of their bioavailability,stability and residency at targeted lung *** with these benefits,nano-based systems also provide additional diagnostic advantages during lung cancer treatment,including imaging,screening and drug ***,delivery of nanobased drugs via pulmonary administration for lung cancer therapy is still in its infancy and numerous challenges are ***,immunology,toxicology and largescale manufacturing(stability and activity of drugs)are some aspects in nanotechnology that should be taken into consideration for the development of inhalable nano-based chemotherapeutic *** review will focus on the current inhalable nano-based drugs for lung cancer treatment.

关键词： Inhalation Lung cancer Liposome Nanoparticle

WAVE ATTENUATION OVER MUD BED: A PSEUDO-PLASTIC MODEL

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Journal of Hydrodynamics 2003年第6期15卷 32-38页

作者： ZhangQing-he OnyxW.H.wai JosephH.W.lee SchoolofCivilEngineering TianjinUniversityTianjin300072China DepartmentofCivilandStructuralEngineering TheHongKongPolytechnicUniversityHongKongChina DepartmentofCivilEngineering TheUniversityofHongKongHongKongChina

A two-layer model, with the upper layer being the perfect fluid and the lowerlayer being the pseudo-plastic fluid describing water wave attenuation over mud bed, wasestablished. A simplified method based on the principle of e-quivalcnt work was applied to solve theboundary value problems. The computational results of the model show that the two-layer perfectfluid model and the perfect-viscous fluid model are all special cases of the present model. Thecomplex nonlinear properties of wave attenuation over mud bed, can be explained by the presentmodel, e. g., the wave dissipation rale decreases wilh the wave height in certain cases, while thesmall wave propagates over mud bed with less energy dissipation and large wave attenuates rapidly inother cases. Other factors influencing the wave attenuation were also discussed.

关键词： wave attenuation mud bed pseudo-plastic model equivalent work

The Relationship of Corporate Culture and Positive Conflict Management

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厦门大学学报（自然科学版） 2002年第S1期41卷 253-254页

作者： wai-Hung Ng S F lee SAE Magnetics （H.K.） Ltd. HKSAR Hong Kong Productivity Council Hong Kong China Hong Kong

With a unique corporate culture based on ancient Ch in ese wisdom being implemented at workplace for more than 10 years, we have been e ncountering various issue of managing conflicts, in particular at organization r estructure period, although we perceive that conflict does not necessarily have dysfunctional effect on our group performance. However, conflicts between and am ong various levels of the organization hierarchy are inevitably creating certain impact on our organization cohesiveness, performa...

关键词： The Relationship of Corporate Culture and Positive Conflict Management

A novel reductive ring-opening reaction of isoxazolidine to form functionalized 1,3-aminoalcohol

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Chinese Chemical Letters 2007年第6期18卷 629-632页

作者： Wing Hong Chan Albert W.M. lee wai Yeung Wong Department of Chemistry Hong Kong Baptist University Kowloog Tong Hong Kong

Reductive cleavage of the NO bond of isoxazolidine ring with catalytic hydrogenation over Raney nickel was described. Bicyclic isoxazolidines could be effectively converted into the corresponding 1,3-amino-alcohol possessing a sultone or sultam moiety with high conversion and yield when the hydrogenation was catalyzed by freshly prepared Raney nickel under a pressure of 40 psi in the presence of triethylamine.

关键词： Isoxazolidine Hydrogenation Raney nickel 1,3-Amino-alcohol