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Pa.tia. Trisomy 1q21-qter a.d Pa.tia. Monosomy 7q21-qter Due to a.Deriva.ive Chromosome 7 in Myelodyspla.tic Syndrome a.socia.ed with Squa.ous Cell Ca.cinoma. Ca.e Report

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Ca.e Reports in Clinica. Medicine 2016年第12期5卷 518-527页

作者： a.dulsa.a. wafa Fa.en Moa.sa.s Thoma. Liehr a.dulmunim a.ja.a.e Wa.id a. a.hka. Chromosomes La.ora.ory Human Genetics Division Molecular Biology and Biotechnology Department Syrian Atomic Energy Commission Damascus Syria Jena.University Hospita. Institute of Human Genetics Jena Germany Flow-Cytometry Unit Mammalians Biology Division Molecular Biology and Biotechnology Department Syrian Atomic Energy Commission Damascus Syria

Ba.kground: Myelodyspla.tic syndromes (MDS) a.e subtypes of hema.ologica. disorders which a.e known to ha.e pa.tia. bone ma.row dyspla.ia. periphera. cytopenia. a.d la.er on a. increa.ed risk to develop a.ute myeloid leukemia. Chromosoma. a.erra.ions a.e detected in ~50% of ca.es of de novo MDS ca.es a.d the most common chromosoma. a.norma.ities of this entity include complete or pa.tia. monosomy of chromosomes 5 a.d 7, pa.tia. deletion of 20q a.d 12p, trisomy 8, a.d 11q23 a.erra.ions. a.few prima.y a.d/or seconda.y MDS ca.es combined with other ca.cer ha.e been reported. Ca.e Presenta.ion: We report here a. a.ult MDS a.socia.ed with squa.ous cell ca.cinoma.(SCC). G-ba.ding a.d a.ra.-proven multicolor ba.ding (a.CB) revea.ed a. unba.a.ced tra.sloca.ion der(7)t(1;7)(q21;q21), which led to 1q pa.tia. trisomy a.d 7q pa.tia. monosomy. Immunophenotype of this ca.e wa. consistent with refra.tory a.emia.with excess of bla.ts (Ra.B-2) a.cording to World Hea.th Orga.iza.ion (WHO) cla.sifica.ion. Conclusions: a. fa. a. we know, this is the first a.ult MDS ca.e a.socia.ed with SCC a.d a. unba.a.ced tra.sloca.ion t(1;7). Our pa.ient received first cycle of a.a.itidine trea.ment a.d he showed bila.era. pleura. effusion a. a.seconda.y event. This toxicity is not limited to the first cycle a. in previous MDS ca.es;our ca.e is the first one to shown this toxicity a. a.seconda.y event of a.a.itidine trea.ment. a. less tha. 10 cytogenetcia.ly compa.a.le ca.es without SCC were reported before in ma.e MDS, we ca.efully conclude tha. this cytogenetic a.erra.ion ma. be a.hint on a.new gender a.socia.ed MDS subgroup.

关键词： Myelodyspla.tic Syndrome (MDS) Cytogenetics Fluorescence in Situ Hybridiza.ion (FISH) Squa.ous Cell Ca.cinoma.(SCC) Prognostic Fa.tors

Single versus combina.ion thera.y in a.ute tocolysis: a.prospective ra.domized controlled tria.

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Open Journa. of Obstetrics a.d Gynecology 2013年第2期3卷 249-256页

作者： wafa R. a.-Oma.i Muzibunnisa.a. Bega. Fa.sa.a.S. Kha. Ima. Y. Khudha.r Nicola.s J. Na.elkerke Depa.tment of Community Medicine Faculty of Medicine and Health Sciences UAE University Al Ain UAE Depa.tment of Obstetrics & Gynecology Tawam/Johns Hopkins Hospital Al Ain UAE

This is a.prospective controlled ra.domized tria. conducted in 92 women with singleton pregna.cies in preterm la.or. The tocolytic effica.y a.d sa.ety of combina.ion a.osiba. a.d nifedipine wa. compa.ed with tha. of the single a.ent, a.osiba.. Both lines of intervention wa. a.ministered for 48 hours. Progression of la.or wa. a.sessed by the frequency of uterine contra.tions a.d cervica. cha.ges. For sta.istica. purpose, intent-to-trea. (ITT) a.a.ysis wa. used throughout. Effica.y, a. determined by the proportion of women in ea.h group who did not deliver a.ter thera.y initia.ion, wa. compa.a.le with no significa.t differences, a. 48 hrs (91.5% vs. 91.1%) a.d a. 7 da.s (90.7% vs. 85.7%) for the a.osiba. a.d the combina.ion groups respectively. Sa.ety wa. a.sessed by the numbers of a.verse events. Ma.erna. side effects were reported more in the combina.ion group (34% vs. 64%;P = 0.006). Perina.a. outcomes were simila. between the groups. We conclude tha. the a.dition of nifedipine did not substa.tia.ly improve the clinica. outcomes beyond tha. were a.hieved with a.osiba. a.one. Moreover, it ha. increa.ed ma.erna. side effects. Future resea.ch could focus on combina.ion of other tocolytics.

关键词： a.osiba. Combina.ion Tocolysis Preterm La.or

The Prognostic Va.ue of BMI, Serum Glucose, Endometria. Echo Pa.tern a.d Uterine a.tery Doppler Velocimetry a. a.Predictor for Endometria. Pa.hology in Women with Postmenopa.sa. Bleeding (Prospective Observa.iona. Study)

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Open Journa. of Obstetrics a.d Gynecology 2020年第1期10卷 13-24页

作者： Yehia.a.wafa a.med T.a.d a.fa.ta. Moha.med Sa.ed Kora.y Depa.tment of Obstetrics a.d Gynecology Faculty of MedicineAl Azhar UniversityCairoEgypt

Ba.kground: Post-menopa.sa. bleeding is a.wa.ning sign tha. a.counts for a.out 5% of a.l outpa.ient gyna.cologic visits a.d is a.common indica.ion for referra. to ra.id a.cess clinics beca.se of the fea. of underlying ma.igna.cy. Endometria. ma.igna.cies differ from other ma.igna.cies in tha. ea.ly symptomiza.ion is common, a.lowing ea.ly cure. Pa.ients a.d Methods: During the study period, 100 women with post-menopa.sa. bleeding ha.ing inclusion criteria.were eva.ua.ed in a. Hussein University Hospita.. For ea.h pa.ient full history, genera., a.domina. a.d pelvic exa.ina.ion wa. performed. Routine pre-opera.ive investiga.ions were done. Pa.ients were divided into four groups: Group 1 included 29 pa.ients with endometria. polyp. Group 2 included 34 pa.ients with endometria. hyperpla.ia. Group 3 included 21 pa.ients with a.rophic endometrium. Group 4 included 16 pa.ients with endometria. ca.cinoma. Results: a. rega.ds the predictive va.ue of BMI, in the study there wa. a.high sta.istica. significa.ce in compa.ison between the endometria. ca.cinoma.group a.d a.l other benign groups. When discussing the predictive va.ue of blood glucose level, in the study there wa. a.high sta.istica. significa.ce in compa.ison between the endometria. ca.cinoma.group a.d a.l other benign groups. It is worth to mention tha. the predictive va.ue of endometria. thickness, in the study, wa. with high sta.istica. significa.ce in compa.ison between the endometria. ca.cinoma.group a.d a.l other benign groups providing the highest specificity a.d sensitivity. a. the la.t the predictive va.ue of uterine a.tery velocimetry, in the study, wa. with high sta.istica. significa.ce in compa.ison between the endometria. ca.cinoma.group a.d a.l other benign groups. Conclusion: BMI, blood glucose level, endometria. thickness a.d uterine a.tery velocimetry indices, improve the prediction of endometria. ca.cinoma.in women with post-menopa.sa. bleeding.

关键词： BMI Serum Glucose Endometria. Echo Pa.tern Uterine a.tery Doppler Velocimetry Endometria. Pa.hology Postmenopa.sa. Bleeding

染色体异常致反复和后代5p12-15.3三体:一对叙利亚夫妇报道及文献复习（英文）

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中华男科学杂志 2015年第3期21卷 219-224页

作者： Wa.id a.-a.HKa. Fa.en Moa.sa.s a.ma. a.-a.log Thoma. Liehr Xia.bo Fa. a.dulsa.a. wafa Depa.tment of Molecula. Biology a.d Biotechnology Human Genetics DivisionAtomic Energy Commission Jena.University Hospita. Institute of Human Genetics

在本研究中,我们介绍一叙利亚夫妻发生孕早期反复流产、胎儿畸形和/或新生儿死亡。经检查,父亲表型正常,有一个平衡的染色体易位t(5;15),在无精子症因子(a.F)b座位s Y125基因发生了微缺失而且其伴有MTHFRC677T纯合子基因多态性。值得注... 详细信息

在本研究中,我们介绍一叙利亚夫妻发生孕早期反复流产、胎儿畸形和/或新生儿死亡。经检查,父亲表型正常,有一个平衡的染色体易位t(5;15),在无精子症因子(a.F)b座位s Y125基因发生了微缺失而且其伴有MTHFRC677T纯合子基因多态性。值得注意的是,他的妻子则伴有MTHFRa.298C纯合子基因多态性。这对夫妻经历了两次流产,有2个夭折的孩子均为严重畸形,为5号染色体短臂部分三体。夫妻结婚10年后没有任何存活后代。

关键词：反复流产染色体异常胎儿畸形死胎 5p三体 Y染色体缺失荧光原位杂交亚甲基四氢叶酸还原酶

Tra.sthora.ic echoca.diogra.hic a.d clinica. predictors in first versus recurrent ischemic strokes

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World Journa. of Ca.diova.cula. Disea.es 2014年第2期4卷 70-76页

作者： Ya.ser Ba.na.y a.r a.o Koora.Ha.ed Da.oud wafa Ra.hed a.i Sa.ek Ca.diology Division Chest Diseases Hospital Ferwania Kuwait Ca.diology Division Department of Medicine Mubarak Al-Kabeer Hospital Hawally Kuwait Neurology Division Depa.tment of Medicine Mubarak Al-Kabeer Hospita Hawally Kuwait Public Hea.th Depa.tment Ministry of Health Ferwania Kuwait

Recurrent strokes a.e more likely to be disa.ling or fa.a. tha. first ever strokes. The a.m of the study is to eva.ua.e tra.sthora.ic echoca.diogra.hic (TTE) a.d clinica. predictors in pa.ients with first versus those with recurrent ischemic strokes. a.prospective observa.iona. compa.a.ive study of 217 pa.ients a.mitted with ischemic strokes who were in sinus rhythm. Two groups of pa.ients were simulta.eously enrolled. The first group wa. 110 pa.ients with first ischemic stroke a.d the second wa. 107 pa.ients with recurrent ischemic stroke. TTE wa. done for a.l pa.ients. Both echoca.diogra.hic a.d clinica. risk fa.tors were compa.ed between both groups. Logistic regression a.a.ysis identified predictors for recurrent strokes. a.ong clinica. risk fa.tors hypertension, hyperlipidemia. fa.ily history of a.herosclerotic va.cula. disea.e, prior corona.y a.tery disea.e, periphera. va.cula. disea.e, a.d chronic kidney disea.e were significa.tly higher in recurrent stroke group. Multiva.ia.e logistic a.a.ysis identified a.e (OR, 1.03;95% CI, 1.01 - 1.07), hypertension (OR, 2.25;95% CI, 1.03 - 4.92), a.d hyperlipidemia.(OR, 2.73;95% CI, 1.40 - 5.35), a. predictors for recurrent ischemic strokes. Left ventricula. dia.tolic dysfunction, left ventricula. hypertrophy (LVH) a.d a.rtic sclerosis were significa.tly more common in the recurrent stroke group compa.ed to the first stroke group. However, in multiva.ia.e logistic a.a.ysis only LVH (OR, 3.50;95% CI, 1.69 - 7.23), wa. identified a. a.predictor for recurrent strokes. Older a.e, hypertension, hyperlipidemia.a.d left ventricula. hypertrophy a.e significa.t predictors of recurrent ischemic strokes in pa.ients with sinus rhythm. Those pa.ients need more a.gressive lipid lowering thera.y a.d optima. blood pressure control.

关键词： Echoca.diogra.hy Risk Fa.tors Predictors Ischemic Stroke

a.study of the rela.ionship between nurses'experience,structura. empowerment,a.d a.titudes towa.d computer use

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Interna.iona. Journa. of Nursing Sciences 2021年第4期8卷 439-443,I0006页

作者： Jeha. a.Ra.a.a. Moha.med M.a.-Ha.mouri wafa’a.F.Ta.a. a.ult Hea.th Nursing Depa.tment Faculty of NursingJordan University of Science and TechnologyIrbidJordan Community a.d Menta. Hea.th Nursing Depa.tment Faculty of NursingJordan University of Science and TechnologyIrbidJordan

Objective:This study exa.ined the rela.ionship between structura. empowerment a.d nurses’experience a.d a.titudes towa.d computer ***:This study wa. conducted using a.cross-sectiona. qua.tita.ive design.a.tota. of 184 registered nurses from four hospita.s in Jorda. pa.ticipa.ed in the current *** were collected using a.demogra.hics questionna.re,the Conditions for Work Effectiveness Questionna.re-II(CWEQ-II),a.d the Pretest for a.titudes towa.d Computers in Hea.thca.e(Pa.CH).Results:The media. of experience in yea.s a.ong nurses wa. 5.0,ra.ging from one to 26 *** mea. score for the a.titudes towa.d computer use wa. 61.90±*** ha.f of the pa.ticipa.ts,45.11%,were in the ca.egory of“feel comforta.le using user-friendly computers.”The pa.ticipa.ts’mea. a.era.e of the tota. structura. empowerment wa. 12.40±2.43,a.d the va.ues for its four subsca.es were:opportunity 3.57±0.87,resources 2.83±0.85,informa.ion 3.06±0.79,a.d support 2.95±*** frequencies a.a.ysis revea.ed tha. most pa.ticipa.ts ha. a.modera.e level of empowerment(n¼127,69.02%).The biva.ia.e correla.ion between nurses’experience a.d a.titudes towa.d computer use wa. significa.t(r¼0.17,Pa.ionship between the tota. structura. empowerment score a.d a.titudes towa.d computer use wa. positive but wea.(r¼0.20,Pa.ed tha. more experienced nurses a.e more relucta.t towa.d computer ***,crea.ing a. empowering work environment ca. fa.ilita.e nurses’a.titudes towa.d computer use.

关键词： a.titude to Computers Empowerment Experience Hospita. nursing sta.f Jorda. Nursing a.ministra.ion resea.ch

Sea.ona. a.d da.ly lfuctua.ion of dia.oms during spring tide periods in Kerkenna. Isla.ds

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Journa. of Coa.ta. Life Medicine 2015年第6期 446-452页

作者： Mounir Ben bra.im wafa Feki-Sa.nouna.Morsi Feki Ma.rouka.Ma.foudi a.ma.Ha.za Fa.ulty of Sciences of Sfa..Roa. of Soukra km 4BP 802-3038 SfaxTunisia Na.iona. Institute of Sciences a.d Technology of the Sea Center of SfaxBP-1035-CP.3018.SfaxTunisia

Objective:To study sea.ona. a.d the da.ly distribution of dia.oms in the three tida. periods(flood,sla.k a.d ebb period)during the spring ***:Wa.er sa.ples were ta.en a.d environmenta. va.ia.les were mea.ured three times in ea.h tida. period during 10 da.s of spring *** wa. done in 2007 in Cercina.sta.ion loca.ed in the western coa.t of Kerkenna.(34°41'27''N;11°07'45''E)(Southern Tunisia..Results:Nutrients showed significa.t va.ia.ion between sea.ons,increa.ing in spring a.d decrea.ing noticea.ly in a.tumn a.d *** 36 dia.om species were *** revea.ed a.rema.ka.le a.unda.ce increa.e in spring a.d *** differences in dia.om a.unda.ces were revea.ed over the tida. periods,with the highest ra.es being detected during the flood a.d the ebb period,while the a.unda.ce ra.e wa. lowest during the sla.k *** could presuma.ly be a.tributed to the increa.e of nutrient supply of suspended pa.ticula.e ma.ter during wa.er *** results revea.ed a.correla.ion between dia.om a.unda.ce a.d tempera.ure,NO_(2)^(-),NO_(3)^(-),Si(OH)_(4) a.d PO_(4)^(3).Tempera.ure seemed to be the most importa.t fa.tors which ma. influence the distribution a.d dia.om ***:Tide ha. va.ious effects on the nutrients sta.us a.d dia.oms community(in terms of species composition,succession a.d a.unda.ce)between different tida. *** of dia.oms wa. correla.ed with cha.ges in the circula.ion of wa.er bodies a.d cha.ges in nutrient regime.

关键词： Dia.oms Tida. periods Sea.ona. va.ia.ility Kerkenna.

Differentia. a.tera.ions of Lipid Sta.us a.d Lipid Meta.olism, Induction of Oxida.ive Stress by Sodium a.sena.e in Fema.e Ra.'s Liver a.d Kidney

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Biomedica. a.d Environmenta. Sciences 2015年第11期28卷 829-833页

作者： Kha.roubi wafa Dhibi Ma.iha.Chreif Imed Géra.d Liza.d Ha.ma.i Moha.ed Sa.ly Ra.hid La.ora.ory of Nutrition-Functiona. Foods a.d Va.cula. Disea.es Faculty of Medicine University of Monastir La.ora.oire Bio-PeroxIL ‘Biochimie du Peroxysome Inflammation et Métabolisme Lipidique’ EA7270/INSERMFaculté des Sciences Gabriel

Three groups of fema.e ra.s （n=6 per group） were exposed to 1 a.d 10 mg/L of sodium a.sena.e for 90 da.s. The a.tioxida.t a.d peroxida.ion pa.a.eters in kidney a.d liver tissues were eva.ua.ed, a.so the fa.ty a.id composition were determined. In liver the synthesis pa.hwa. of n-3 polyunsa.ura.ed fa.ty a.ids （PUFa. seemed to be more a.fected tha. the n-6 PUFa. while in kidney the n-6 pa.hwa. wa. more a.fected.

关键词： PUFA Differentia. a.tera.ions of Lipid Sta.us a.d Lipid Meta.olism

Fetoscopy Role in Feta. Surgery a.d Feta. Medicine

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Open Journa. of Obstetrics a.d Gynecology 2019年第11期9卷 1477-1485页

作者： Wa.l S. S. Elba.na.Ibra.im a. Oun Ema. M. a.d Ella.if Wa.l R. Ha.la. Wa.id I. El Sha.kh Yehia.a. wafa Depa.tment of Obstetrics & Gynecology Al-Azhar University Cairo Egypt Depa.tment of Clinica. Pa.hology Al-Azhar University Cairo Egypt

a.m: We a.tempted to illustra.e our experience of fetoscopic thera.y in a.tertia. institute, whereby to highlight the present Egyptia. situa.ion rega.ding this issue. We described fetoscopic thera.y undergone a. a.-Hussein Hospita., a.-a.ha. University, Ca.ro, Egypt, from Dec-2012 to Sep-2019. Presenta.ion of ca.es: Sixteen women with 17 fetuses were included in the a.a.ysis of this study with a.mea. a.e of 25.31 ± 6.15 yea.s;four with positive ma.ria.e to a.nea. releva.t, a.d eight were primigra.ida. The fetus of twelve women ha. lower urina.y tra.t obstruction (LUTO), two feta. a.emia. one hydrothora., a.d one twin-to-twin tra.sfusion syndrome (TTTS). The mea. time for fetoscopy wa. gesta.iona. week 24.13 ± 3.77. We did thera.eutic dra.na.e to a.niotic fluid in hydrothora. a.d LUTO, thera.eutic septostomy to the TTTS ca.e, a.d blood tra.sfusion in ca.es of feta. a.emia. During the opera.ion, the procedure succeeded in 14 out of 16 women. Overa.l, nine of the 16 women experienced some complica.ions;five with rupture of membra.es, four with preterm la.or, a.d three with intra.terine feta. dea.h (IUFD). Conclusion: Fetoscopy ca. ma.a.e LUTO a.d well-selected ca.es of TTTS, hydrothora., a.d feta. a.emia. The procedure is promising. Fetoscopic thera.y ha. just begun in Egypt, a.d this report ma. contribute to the future a.va.ce of fetoscopic thera.y in Egypt.

关键词： Fetoscopy Lower Urina.y Tra.t Obstruction LUTO Twin-to-Twin Tra.sfusion Syndrome Feta. a.emia Complica.ions Ra.e