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Effects of Mo and Zr on Microstructure,Mechanical Properties and wear Resistance of Fe-Al Based Alloys

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Journal of Materials Science & Technology 2008年第3期24卷 309-312页

作者： I.D.yeo H.S.kim y.G.yoo w.y.kim Advanced Materials R&D Division Korea Institute of Industrial Technology7-47Songdo-dongYeonsu-gu

In this work the microstructure, mechanical properties and wear resistance of Fe-Al based alloys with various alloying elements were studied. The microstructures were examined by optical and scanning electron microscopy （SEM） equipped with an energy dispersive X-ray spectroscope （EDS）. Two types of alloys were prepared by vacuum arc melting. One is Fe-28Al based alloys （D03 structured） with and without alloying elements such as Mo and Zr. The other one is Fe-35Al based alloys （B2 structured） produced with the same manner. For both types of alloys, Mo addition had found to exhibit an equiaxed microstructure, while dendritic structure was observed to show the effect of Zr addition. These microstructural features were more evinced with increasing content of alloying element. Concerning the mechanical properties and wear resistance, Fe-35Al based alloys were superior to Fe-28Al based alloys over the whole temperature range investigated.

关键词： Fe-Al alloy Intermetallic Mechanical properties wear resistance

Microstructure,Elastic Modulus and Tensile Properties of Ti-Nb-O Alloy System

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Journal of Materials Science & Technology 2008年第1期24卷 33-36页

作者： H.S.kim T.y.Ra I.D.yeo H.J.Bang y.G.yoo w.y.kim Advanced Materials R＆D Division Korea Institute of Industrial Technology Incheon 406-800 Korea

In the present study Ti-Nb binary alloy system was chosen because it has excellent biocompatibility as well as reasonable mechanical properties,aiming at understanding oxygen content on microstructural formation, elastic modulus and tensile properties in Ti-Nb alloy *** alloy buttons of 50 mm in diameter were prepared by arc melting on a water-cooled copper hearth under an argon gas atmosphere with a non-consumable tungsten *** button ingots were then heat treated in a vacuum atmosphere at 1273 K for 0.5 h followed by water quenching in a specially designed heat treatment ***,elastic modulus and tensile properties were investigated in order to understand the effect of oxygen content in quenched Ti- Nb alloy *** orthorhombic structuredα″martensite was changed to bcc structuredβ-phase with increasing Nb ***,it was found that oxygen makesβ-phase stable in quenched Ti-Nb alloy *** modulus values were sensitive to phase stability of constituent *** strength increased with increasing oxygen *** will be explained by phase formation and stability behavior.

关键词： Ti-Nb-O alloy Phase stability Elastic modulus Mechanical properties

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加利福尼亚湾南部地震和断层作用的机制

世界地震译丛 2013年第5期44卷 24-51页

作者： D.F.Sumy J.B.Gaherty w.y.kim T.Diehl J.A.Collins 李守勇(译) 张黎晓(译) 赵爱平(译) 不详河北省地震局邯郸中心台

地震精定位及其震源机制可以说明断裂的大陆边缘形变的分布和模式。加利福尼亚湾（GoC）内的太平洋一北美（Pa-NA）板块边界由于北部的大陆扩张到南部转变成海底扩张而提供了研究断裂演化和运动学的极好机会。从2005年10月至2006年10月... 详细信息

地震精定位及其震源机制可以说明断裂的大陆边缘形变的分布和模式。加利福尼亚湾（GoC）内的太平洋一北美（Pa-NA）板块边界由于北部的大陆扩张到南部转变成海底扩张而提供了研究断裂演化和运动学的极好机会。从2005年10月至2006年10月，作为科特斯海海底台阵（SCOOBA）试验的一部分，在加利福尼亚湾布设的8个四分量海底地震计的台阵记录了地震活动。通过将这次记录数据与自动记录地震（NARs）-Baja台阵陆上台网的观测资料相结合，我们主要沿勾画出板块边界的北西一南东走向的转换断层观测并定位了约700个地震（A‰2．2～6．6）。对于在长周期（10～20s）频带具有高信噪比的36个地震事件（Mw3．5～6．6），我们通过区域地震波形反演确定了偏矩张量和有关的双力偶震源机制。很多震源机制与沿太平洋一北美转换断层系的右旋走滑断层作用一致，说明这些转换断层主要调节着该海湾内的地震形变。另外，我们在下加利福尼亚上沿右旋北西～南东走向的拉斯比沃拉斯一埃尔阿苏夫雷断层捕捉到可能与该半岛内正在进行的地热活动和火山形变有关的地震群。高分辨率的地震定位与震源机制相结合，提高了我们对加利福尼亚湾南部更大扩张区内地震形变分布的了解。

关键词：加利福尼亚湾走滑断层作用地震精定位震源机制南部海底扩张地震波形反演地震形变

添加蛋氨酸壳聚糖酵母形式的螯合铜对肉仔鸡生产性能的影响

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江西饲料 2007年第1期 32-35页

作者： H.S.Lim I.K.Paik T.I.Sohn w.y.kim 许云贺（译）张莉力（校）不详辽宁医学院畜牧兽医学院

试验研究了添加蛋氨酸螯合铜(Met-Cu)、壳聚糖螯合铜(Chitosan-Cu)、酵母螯合铜(yeast-Cu)对肉仔鸡生产性能、营养物质消化率、血清IGg水平、嗉囊腐蚀程度、肝脏和排泄物中铜(Cu)含量以及肌肉和血清中总胆固醇的水平的影响。240只肉仔鸡... 详细信息

试验研究了添加蛋氨酸螯合铜(Met-Cu)、壳聚糖螯合铜(Chitosan-Cu)、酵母螯合铜(yeast-Cu)对肉仔鸡生产性能、营养物质消化率、血清IGg水平、嗉囊腐蚀程度、肝脏和排泄物中铜(Cu)含量以及肌肉和血清中总胆固醇的水平的影响。240只肉仔鸡(Ross208)平均分配到4个处理组中:对照组、Met-Cu组、Chitosan-Cu组、yeast-Cu组。3个螯合铜试验组日粮铜含量均为100mg/kg。每个处理组中设6个重复,每个重复10只鸡(5只公鸡+5只母鸡)。试验结果表明,螯合铜试验组增重和采食量均高于对照组。Met-Cu组增重显著高于对照组(Pyeast-Cu组采食量显著高于对照组(Pyeast-Cu组。各组间干物质利用率差异显著(P<0.05),螯合铜的试验组干物质利用率显著高于对照组,其中Chitosan-Cu组最高。添加螯合铜提高了嗉囊腐蚀系数,Met-Cu组肝脏铜含量最高。添加螯合铜降低了胸肌和血清中总胆固醇水平,而提高了血清高密度脂蛋白(HDL)水平。试验结果表明,在肉仔鸡日粮中以螯合铜形式添加铜100mg/kg,可以提高增重、采食量和干物质利用率,其中Met-Cu效果最好。

关键词：蛋氨酸螯合铜壳聚糖螯合铜酵母螯合铜肉仔鸡

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons

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Neural Regeneration Research 2025年第7期20卷 1999-2000页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(Cleveland and Rothstein,2001).Frontotemporal lobar degeneration(FTLD)is a neurodegenerative disease affecting the frontal and temporal lobes of the brain,leading to changes in behavior,personality,and language(Van Langenhove et al.,2012).Both ALS and FTLD are classified as proteinopathies in which abnormal protein aggregation and accumulation in neurons contribute to the disease *** in sarcoma(FUS)is a DNA/RNA-binding protein involved in various cellular processes,including transcriptional regulation,RNA splicing,and DNA *** in the FUS gene have been linked to familial ALS,highlighting the importance of FUS in the disease pathogenesis(Vance et al.,2009).In ALS and FTLD,aberrant post-translational modifications(PTMs)of FUS,such as phosphorylation,acetylation,and methylation,have been implicated in the promotion of FUS aggregation and neurotoxicity(Choi et al.,2023).Therefore,understanding the regulatory mechanisms of FUS PTMs is crucial for developing targeted therapies against these diseases.

关键词： degeneration FUS aggregation

Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis

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Neural Regeneration Research 2025年第8期20卷 2319-2320页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS),also known as Lou Geh rig's disease,is a progressive neurodegenerative disorder that affects motor neurons in the brain and spinal *** leads to muscle weakness,paralysis,and ultimate... 详细信息

关键词： paralysis sclerosis respiratory

纽约世贸中心大楼遭飞机撞击和大楼坍塌产生的地震波

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世界地震译丛 2002年第5期33卷 74-79页

作者： w.y.kim L.R.Sykes J.H.Armitage J.K.Xie K.H.Jacob P.G.Richards M.west F.waldhauser J.Armbruster L.Seeber w.X.Du A.Lerner-Lam 万永革中国地震局防灾技术高等专科学校

地震学家有时是在悲剧的背景下进行数据采集和分析工作的。这通常所指的是远离家乡在经受天然、有时是坡坏性地震影响的地区的野外工作。但目前的情况是,我们是在我们自己的城市,即纽约帕利塞兹哥伦比亚大学拉蒙特-多赫蒂地球观测站,面... 详细信息

地震学家有时是在悲剧的背景下进行数据采集和分析工作的。这通常所指的是远离家乡在经受天然、有时是坡坏性地震影响的地区的野外工作。但目前的情况是,我们是在我们自己的城市,即纽约帕利塞兹哥伦比亚大学拉蒙特-多赫蒂地球观测站,面对的是反人民、反我们社会结构的野蛮活动。

关键词：纽约世界中心大楼飞机撞击坍塌地震波

Recovery of the injured neural system through gene delivery to surviving neurons in Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2855-2861页

作者： Chanchal Sharma Sehwan kim Hyemi Eo Sang Ryong kim School of Life Science Kyungpook National UniversityDaeguKorea BK21 FOUR KNU Creative BioResearch Group Kyungpook National University DaeguKorea Brain Science and Engineering Institute Kyungpook National UniversityDaeguKorea

A critical unaddressed problem in Parkinson’s disease is the lack of therapy that slows or hampers *** medications effectively manage symptoms,they offer no long-term benefit because they fail to address the underlying neuronal *** highlights that the elusive goals of halting progression and restoring damaged neurons limit the long-term impact of current *** clinical trials using gene therapy have demonstrated the safety of various vector delivery systems,dosages,and transgenes expressed in the central nervous system,signifying tangible and substantial progress in applying gene therapy as a promising Parkinson’s disease ***,at diagnosis,many dopamine neurons remain in the substantia nigra,offering a potential window for recovery and *** propose that modulating these surviving dopamine neurons and axons in the substantia nigra and striatum using gene therapy offers a potentially more impactful therapeutic approach for future ***,innovative gene therapies that focus on preserving the remaining elements may have significant potential for enhancing long-term outcomes and the quality of life for patients with Parkinson’s *** this review,we provide a perspective on how gene therapy can protect vulnerable elements in the substantia nigra and striatum,offering a novel approach to addressing Parkinson’s disease at its core.

关键词： adeno-associated virus gene therapy neuroprotection neurorestoration neurotrophic factor nigrostriatal dopamine pathway pro-survival protein

High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

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Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki kim Bum Jun kim Seungyon Koh Hyo Jin Cho Xuelian Jin Byung Gon kim Jun young Choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration