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马氏体冷轧-回火制备超细晶钢及其热稳定性

材料研究学报 2008年第3期22卷 279-286页

作者：蓝慧芳 w.j.liu 刘相华东北大学轧制技术及连轧自动化国家重点实验室沈阳110004 Graduate Institute of Ferrous Technology POSTECH Pohang 790-784 Korea

在低碳钢和低碳加铌、钒、钛微合金钢中,通过马氏体冷轧-回火的方法获得了尺寸为数百纳米的超细晶粒铁素体组织,研究了超细晶粒组的形成机制和热稳定性.通过马氏体相变在这些钢中引入了大量高密度位错,马氏体冷轧后位错进一步增殖,形成... 详细信息

在低碳钢和低碳加铌、钒、钛微合金钢中,通过马氏体冷轧-回火的方法获得了尺寸为数百纳米的超细晶粒铁素体组织,研究了超细晶粒组的形成机制和热稳定性.通过马氏体相变在这些钢中引入了大量高密度位错,马氏体冷轧后位错进一步增殖,形成大量位错胞状结构;在500-600℃进行的60 min回火将上述胞状结构转变成具有清晰大角晶界的超细晶粒.在回火过程中形成的微合金元素碳化物对位错运动和晶界移动具有有效的"钉扎"作用,有助于获得超细晶组织并明显提高其热稳定性.

关键词：金属材料超细晶冷轧马氏体回火微合金钢

Analytical approximations to large amplitude free vibration behaviors of electrostatically actuated microbeams

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Analytical approximations to large amplitude free vibration ...

Strong Anisotropy of KTiOPO4 Crystals under an Electric Field Observed by Synchrotron Radiation Topography

第三届海峡两岸动力学、振动与控制学术会议

作者：吴柏生 w.j.liu Department of Mechanics and Engineering Science School of Mathematics Jilin University Department of Mechanics and Engineering Science School of MathematicsJilin University

The conservation of energy principle is used to evaluate the large amplitude free vibration behaviors of an axially stressed clamped-clamped microbeam subjected to one-sided and two-sided symmetric electrostatic actuations. with an assumed space mode, which satisfies the geometric boundary conditions of the beam, the final nonlinear governing equation is obtained. Based on the original the non-odd nonlinear oscillator, two new oscillators with odd nonlinearity are first addressed. Utilizing the analytical

关键词： Analytical approximations to large amplitude free vibration behaviors of electrostatically actuated microbeams

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同步辐射装置用户科技论文集 1999年第1期 199-204页

作者： w.j.liu j.Y.wANG 等 NationalLaboratoryofSolidStateMicrostructures NanjingUniversityNanjing210093P.R.China InstituteofCrystalMaterials ShandongUniversityJinan250100P.R.China

In-situ white-beam synchrotron radiation topographic observations under an electric field have been made on KTiOPO4 family *** investigation shows a strong enhancement of diffracted intensity of hkl reflections(l≠0) and the topographic extinction contrast,when the field is applied along the polar *** and undoped samples with grown-in defects are studied in *** is believed that the movement of K^+ ions driven by the field leads to a local accumulation of charges and the lattice *** the field-related phenomena appear to be related to the one-dimensional ionic conductance.

关键词： KTiOPO4晶体电场同步辐照地形观测

Growth Twinning in Self—Frequency—Doubling Laser Crystal NdxGd1—xAl3（BO3）4 Observed with white—Beam Synchrotron Radiation Topography

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同步辐射装置用户科技论文集 1998年第1期 151-157页

作者： X.B.Hu w.j.liu

A Study on Visualized Field Distribution of Intensive Microwave Field

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A Study on Visualized Field Distribution of Intensive Microw...

Interplay between creeping fat and gut microbiota: A brand-new perspective on fecal microbiota transplantation in Crohn's disease

2006 7th International Symposium on Antennas, Propagation and EM Theory

作者： G.L.Sun w.X.Li Z.F.Yang w.j.liu Department of electronic Information Science and Technology Nankai University

The measurement of the distribution of intensive microwave field based on a new method which is put up by designing a testing container and 'Multi-channeled,Synchronous,Temperature sampling and processing system' in this *** the method,it is possible to describe the distribution of microwave field and achieve the visualization of the distribution of microwave power by use of *** is proved by experiments that this method is feasible and reliable.

关键词： field distribution multi-channeled synchronous temperature sampling MATLAB

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world journal of Gastroenterology 2025年第2期31卷 138-143页

作者： Ying wang jie liu Department of Life Sciences and Medicine South District of Endoscopic CenterThe First Affiliated Hospital of University of Science and Technology of ChinaUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Gastroenterology The First Affiliated Hospital of University of Science and Technology of ChinaHefei 230001Anhui ProvinceChina

Inflammatory bowel disease,particularly Crohn's disease(CD),has been linked to modifications in mesenteric adipose tissue(MAT)and the phenomenon known as"creeping fat"(CrF).The presence of CrF is believed to serve as a predictor for early clinical recurrence following surgical intervention in patients with ***,the incorporation of the mesentery during ileocolic resection for CD has been correlated with a decrease in surgical recurrence,indicating the significant role of MAT in the pathogenesis of *** numerous studies have indicated that dysbiosis of the gut microbiota is a critical factor in the development of CD,the functional implications of translocated microbiota within the MAT of CD patients remain *** manuscript commentary discusses a recent basic research conducted by wu et *** their study,intestinal bacteria from individuals were transplanted into CD model mice,revealing that fecal microbiota trans-plantation(FMT)from healthy donors alleviated CD symptoms,whereas FMT from CD patients exacerbated these ***,FMT was found to affect intestinal permeability,barrier function,and the levels of proinflammatory factors and ***,these findings suggest that targeting MAT and CrF may hold therapeutic potential for patients with ***,the study did not evaluate the composition of the intestinal microbiota of the donors or the subsequent alterations in the gut ***,the gut microbiota plays a crucial role in the histopathology of CD,and thus,targeting MAT and CrF may represent a promising avenue for treatment in this patient population.

关键词： Crohn's disease Mesenteric adipose tissue Creeping fat Fecal microbiota transplantation Gut microbiota

Network pharmacology:Changes the treatment mode of"one disease-one target"in cancer treatment

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world journal of Gastrointestinal Oncology 2025年第1期17卷 268-271页

作者： Shuai liu Yong-wei Yu Department of Cardiology The First People’s Hospital of JiashanJiaxing 314100Zhejiang ProvinceChina Department of Critical Care Medicine The First Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina

The article concluded that network pharmacology provides new ideas and insights into the molecular mechanism of traditional Chinese medicine(TCM)treatment of *** is a new choice and hot spot in the field of cancer *** have also previously published studies on TCM and network *** this letter,we summarize the new paradigm of network pharmacology in cancer treatment mechanisms.

关键词： Network pharmacology Cancer Multicomponent Multitarget Therapy

Interconnections between diabetic corneal neuropathy and diabetic retinopathy:diagnostic and therapeutic implications

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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi Yu Faith Teo En Ning Chang liu Yu-Chi liu Tissue Engineering and Stem Cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of Cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives

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Neural Regeneration Research 2025年第10期20卷 2758-2775页

作者： Tianlong liu Xiaolin Li Xiaowei Zhou wei Chen Aidong wen Minna liu Yi Ding Department of Pharmacy Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Department of Pharmacy The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina Department of Pharmacy The 944 Hospital of Joint Logistics Support Forces of Chinese PLAJiuquanGansu ProvinceChina Department of Nephrology The 940 Hospital of Joint Logistics Support Forces of Chinese PLALanzhouGansu ProvinceChina

It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic *** a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing attention from *** article reviews the pathological mechanisms and advancements in research related to the signaling pathways in ischemic stroke,with a focus on the PI3K/AKT signaling *** key findings include the following:(1)The complex pathological mechanisms of ischemic stroke can be categorized into five major types:excitatory amino acid toxicity,Ca^(2+)overload,inflammatory response,oxidative stress,and apoptosis.(2)The PI3K/AKT-mediated signaling pathway is closely associated with the occurrence and progression of ischemic stroke,which primarily involves the NF-κB,NRF2,BCL-2,mTOR,and endothelial NOS signaling pathways.(3)Natural products,including flavonoids,quinones,alkaloids,phenylpropanoids,phenols,terpenoids,and iridoids,show great potential as candidate substances for the development of innovative anti-stroke medications.(4)Recently,novel therapeutic techniques,such as electroacupuncture and mesenchymal stem cell therapy,have demonstrated the potential to improve stroke outcomes by activating the PI3K/AKT signaling pathway,providing new possibilities for the treatment and rehabilitation of patients with ischemic *** investigations should focus on the direct regulatory mechanisms of drugs targeting the PI3K/AKT signaling pathway and their clinical translation to develop innovative treatment strategies for ischemic stroke.

关键词： apoptosis autophagy inflammation ischemic stroke neuroprotection oxidative stress pathogenesis phosphatidylinositol 3-kinase protein kinase B therapeutics