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Geometrical reconstruction of fluorescence events observed by the LHAASO experiment

Chinese Physics C 2021年第4期45卷 416-425页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi H.Cai j.T.Cai Z.Cao Z.Cao j.Chang j.F.Chang X.C.Chang B.M.Chen j.Chen L.Chen L.Chen L.Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu D.della Volpe B.DEtorre Piazzoli X.j.Dong j.H.Fan Y.Z.Fan Z.X.Fan j.Fang j.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao w.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He j.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang Q.L.Huang w.H.Huang X.T.Huang Z.C.Huang F.ji X.L.ji H.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li j.Li K.Li w.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood w.Mitthumsiri T.Montaruli Y.C.Nan B.Y..Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Saiz L.Shao O.Shchegolev X.D.Sheng j.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wang C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wang R.N.wang w.wang w.wang X.G.wang X.j.wang X.Y.wang Y.D.wang Y.j.wang Y.P.wang Z.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang j.Y.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.F.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao j.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou j.N.Zhou P Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Paricle Detection and Electronics China University of Science and Technology of China HefeiAnhui 230026China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhouGuangdong 510006China School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhaiGuangdong 519000China School of Physical Science and Technology Guangxi UniversityNanningGuangxi 530004China Hebei Normal University ShijiazhuangHebei 050024China School of Physics and Microelectronics Zhengzhou UniversityZhengzhouHenan 450001China School of Astronomy and Space Science Nanjing UniversityNanjingJiangsu 210023China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjingJiangsu 210023China Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdaoShandong 266237China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology Southwest Jiaotong UniversityChengduSichuan 610031China College of Physics Sichuan UniversityChengduSichuan 610065China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasaTibet 850000China School of physics and technology Wuhan UniversityWuhanHubei 430072Ch

The LHAASO-wFCTA experiment,which aims to observe cosmic rays in the sub-EeV range using the fluorescence technique,uses a new generation of high-performance *** ensure that the experiment has ex-cellent detection capability associated with the measurement of the energy spectrum,the primary composition of cosmic rays,and so on,an accurate geometrical reconstruction of air-shower events is *** paper de-scribes the development and testing of geometrical reconstruction for stereo viewed events using the wFCTA(wide Field of view Cherenkov/Fluorescence Telescope Array)*** approaches,which take full advantage ofthe wFCTA *** *** is the stereo-angular method,which uses the pointing of triggered SiPMs in the shower trajectory,and the other is the stereo-timing method,which uses the triggering time of the fired *** results show that both methods have good geometrical resolution:the resolution of the stereo-timing method is slightly better than the stereo-angular method because the resolution of the latter is slightly limited by the shower track length.

关键词： cosmic ray fluorescence telescope stereo observation geometrical reconstruction

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Observation of the Crab Nebula with LHAASO-KM2A−a performance study

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Chinese Physics C 2021年第2期45卷 518-530页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi H.Cai j.T.Cai Z.Cao j.Chang j.F.Chang X.C.Chang B.M.Chen j.Chen L.Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai D.della Volpe B.D'Ettorre Piazzoli X.j.Dong j.H.Fan Y.Z.Fan Z.X.Fan j.Fang K.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao w.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He j.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang Q.L.Huang w.H.Huang X.T.Huang Z.C.Huang F.ji X.L.ji H.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.Levochkin B.B.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li j.Li K.Li w.L.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood w.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng j.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wang C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wang R.N.wang w.wang X.G.wang X.j.wang X.Y.wang Y.D.wang Y.j.wang Y.P.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang j.Y.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao j.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou j.N.Zhou P.Zhou R.Zhou X.X.Zhou C.G.Zhu F.R.Zhu H.Zhu K.j.Zhu X.Zuo Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of Sciences100049 BeijingChina University of Chinese Academy of Sciences 100049 BeijingChina TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China 230026 HefeiAnhuiChina Department of Engineering Physics Tsinghua University100084 BeijingChina National Astronomical Observatories Chinese Academy of Sciences100101 BeijingChina National Space Science Center Chinese Academy of Sciences100190 BeijingChina School of Physics Peking University100871 BeijingChina Center for Astrophysics Guangzhou University510006 GuangzhouGuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen University519000 ZhuhaiGuangdongChina School of Physical Science and Technology Guangxi University530004 NanningGuangxiChina Hebei Normal University 050024 ShijiazhuangHebeiChina School of Physics and Microelectronics Zhengzhou University450001 ZhengzhouHenanChina School of Astronomy and Space Science Nanjing University210023 NanjingJiangsuChina Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of Sciences210023 NanjingJiangsuChina Institute of Frontier and Interdisciplinary Science Shandong University266237 QingdaoShandongChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of Sciences200030 ShanghaiChina Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong University200240 ShanghaiChina School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong University610031 ChengduSichuanChina College of Physics Sichuan University610065 ChengduSichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of Education850000 LhasaTibetChina School of Physics and Tec

A sub-array of the Large High Altitude Air Shower Observatory(LHAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 *** though the detector construction is still underway,half of the KM2A array has been operating stably since the end of *** this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray *** detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May *** the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection *** energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other *** opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered.

关键词： γ-ray Crab Nebula extensive air showers cosmic rays

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The complex effects of miR-146a in the pathogenesis of Alzheimer's disease

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Neural Regeneration Research 2025年第5期20卷 1309-1323页

作者： Yunfan long jiajia Liu Yu wang Haidong Guo Guohong Cui Department of Neurology Shanghai No.9 People’s HospitalShanghai Jiaotong University School of MedicineShanghaiChina Academy of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina School of Integrative Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Department of Neurology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina

Alzheimer's disease is a neurodegenerative disorder characterized by cognitive dysfunction and behavioral *** plaques formed through the extracellular deposition of amyloid-βproteins,as well as neurofibrillary tangles formed by the intracellular deposition of hyperphosphorylated tau proteins,comprise two typical pathological features of Alzheimer's *** symptomatic treatment,there are no effective therapies for delaying Alzheimer's disease ***(miR)are small,non-coding RNAs that negatively regulate gene expression at the transcriptional and translational levels and play important roles in multiple physiological and pathological ***,miR-146a,a NF-κB-regulated gene,has been extensively implicated in the development of Alzheimer's disease through several *** has demonstrated substantial dysregulation of miR-146a both during the initial phases and throughout the progression of this *** R-146a is believed to reduce amyloid-βdeposition and tau protein hyperphosphorylation through the TLR/IRAK1/TRAF6 pathway;however,there is also evidence supporting that it can promote these processes through many other pathways,thus exacerbating the pathological manifestations of Alzheimer's *** has been widely reported that miR-146a mediates synaptic dysfunction,mitochondrial dysfunction,and neuronal death by targeting m RNAs encoding synapticrelated proteins,mitochondrial-related proteins,and membrane proteins,as well as other *** the impact on glial cells,miR-146a also exhibits differential *** one hand,it causes widespread and sustained inflammation through certain pathways,while on the other hand,it can reverse the polarization of astrocytes and microglia,alleviate neuroinflammation,and promote oligodendrocyte progenitor cell differentiation,thus maintaining the normal function of the myelin sheath and exerting a protective effect on *** this review,we provide a

关键词： Alzheimer's disease amyloid-β glial cells microRNAs miR-146a neuroinflammatory

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Reconstruction of Cherenkov image bymultiple telescopes of LHAASO-wFCTA

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Radiation Detection Technology and Methods 2022年第4期6卷 544-557页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi j.T.Cai Zhe Cao Zhen Cao j.Chang j.F.Chang E.S.Chen Liang Chen Liang Chen long Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen Y.Chen H.L.Cheng N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.D’Ettorre Piazzoli B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu Ddella Volpe K.K.Duan j.H.Fan Y.Z.Fan Z.X.Fan j.Fang K.Fang C.F.Feng L.Feng S.H.Feng X.T.Feng Y.L.Feng B.Gao C.D.Gao L.Q.Gao Q.Gao w.Gao w.K.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu F.L.Guo j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu Q.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang w.H.Huang X.T.Huang X.Y.Huang Y.Huang Z.C.Huang X.L.ji H.Y.jia K.jia K.jiang Z.j.jiang M.jin M.M.Kang T.Ke D.Kuleshov K.Levochkin B.B.Li Cheng Li Cong Li F.Li H.B.Li H.C.Li H.Y.Li j.Li jian Li jie Li K.Li wLLi XRLi Xin Li Xin Li YZLi Zhe Li Zhuo Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.Liu Y.N.Liu w.j.long R.Lu Q.Luo H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood Z.Min w.Mitthumsiri Y.C.Nan Z.w.Ou B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi Y.Q.Qi B.Q.Qiao j.j.Qin D.Ruffolo A.Sáiz C.Y.Shao L.Shao O.Shchegolev X.D.Sheng j.Y.Shi H.C.Song Yu.V.Stenkin V.Stepanov Y.Su Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wang C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wang R.wang R.N.wang w.wang X.G.wang X.Y.wang Y.wang Y.D.wang Y.j.wang Y.P.wang Z.H.wang Z.X.wang Zhen wang Zheng wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu X.F.wu Y.S.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang D.X.Xiao G.Xiao G.G.Xin Y.L.Xin Y.Xing Z.Xiong D.L.Xu R.X.Xu L.Xue D.H.Yan j.Z.Yan C.w.Yang F.F.Yang H.w.Yang j.Y.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.Yue H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang F.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang L.X.Zhang Li Zhang Lu Zhang P.F.Zhang P.P.Zhang R.Zhang S.B.Zhang S.R.Zhang S. Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2DublinIreland Max-Planck-Institut for Nuclear Physics P.O.Box 10398069029 HeidelbergGermany State Key Laboratory of Particle Detection and Electronics BeijingChina University of Science and Technology of China Hefei 230026AnhuiChina School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031SichuanChina College of Physics Sichuan UniversityChengdu 610065SichuanChina School of Astronomy and Space Science Nanjing UniversityNanjing 210023JiangsuChina Center for Astrophysics Guangzhou UniversityGuangzhou 510006GuangdongChina Key Laboratory of Dark Matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023JiangsuChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Hebei Normal University Shijiazhuang 050024HebeiChina School of Physics and Astronomy(Zhuhai)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000China School of Physics(Guangzhou) Sun Yat-sen UniversityGuangzhou 510275GuangdongChina Dipartimento di Fisica dell’Universitàdi Napoli“Federico II” Complesso Universitario di Monte Sant’Angelovia Cinthia80126 NapoliItaly School of Physics and Astronomy Yunnan UniversityKunming 650091YunnanChina Département de Physique Nucléaire et Corpusculaire Facultéde SciencesUniversitéde Genève

Introduction One of main scientiﬁc goals of the Large High Altitude Air Shower Observatory(LHAASO)is to accurately measure the energy spectra of different cosmic ray compositions around the‘knee’*** wide Field-of-View(FoV)Cherenkov Telescope Array(wFCTA),which is one of the main detectors of LHAASO and has 18 telescopes,is built to achieve this *** telescopes are put together and point to connected directions for a larger *** Telescopes are deployed spatially as close as possible,but due to their own size,the distance between two adjacent telescopes is about 10 ***,the Cherenkov lateral distribution and the parallax between the two telescopes should be considered in the event building process for images crossing over the boundaries of FoVs of the *** event building method for Cherenkov images measured by multiple telescopes of wFCTA is *** performance of the shower measurements using the combined images is evaluated by comparing with showers that are fully contained by a virtual telescope in *** and conclusion It is proved that the developed event building process can help to increase the FoV of wFCTA by 30%while maintaining the same reconstruction quality,compared to the separate telescope reconstruction method.

关键词： method directions conclusion

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Line-of-shower trigger method to lower energy threshold for GRB detection using LHAASO-wCDA

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Radiation Detection Technology and Methods 2021年第4期5卷 531-541页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi H.Cai j.T.Cai Z.Cao Z.Cao j.Chang j.F.Chang X.C.Chan B.M.Chen j.Chen L.Chen L.Chen L.Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Chen Y.D.Chen S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu D.della Volpe B.D’Ettorre Piazzoli X.j.Don j.H.Fan Y.Z.Fan Z.X.Fan j.Fang K.Fan C.F.Feng L.Feng S.H.Fen Y.L.Feng B.Gao C.D.Gao Q.Gao w.Gao M.M.Ge L.S.Gen G.H.Gong Q.B.Gou M.H.Gu j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He j.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang Q.L.Huan w.H.Huang X.T.Huang Z.C.Huang F.ji X.L.ji H.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li j.Li K.Li w.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood w.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Shen j.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wan C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wan R.N.wang w.wang w.wang X.G.wang X.j.wan X.Y.wang Y.D.wan Y.j.wan Y.P.wang Z.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang j.Y.Yang L.L.Yang M.j.Yan R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhan X.Zhang X.P.Zhan Y.Zhan Y.Zhang Y.F.Zhang Y.L.Zhan B.Zhao j.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou j.N.Zhou P.Zhou R.Zhou X.X.Zhou C.G. Key Laboratory of Particle Astrophysics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics BeijingChina University of Science and Technology of China Hefei 230026AnhuiChina Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006GuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhai 519000GuangdongChina School of Physical Science and Technology Guangxi UniversityNanning 530004GuangxiChina Hebei Normal University Shijiazhuang 050024HebeiChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001HenanChina School of Astronomy and Space Science Nanjing UniversityNanjing 210023JiangsuChina Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023JiangsuChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237ShandongChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031SichuanChina College of Physics Sichuan UniversityChengdu 610065SichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina School of Physic

Purpose Observation of high energy and very high emission from Gamma Ray Bursts(GRBs)is crucial to study the gigantic explosion and the underline *** a large field-of-view and almost full duty cycle,the water Cherenkov Detector Array(wCDA),a sub-array of the Large High Altitude Air Shower Observatory(LHAASO),is appropriate to monitor the very high energy emission from unpredictable transients such as *** Nevertheless,the main issue for an extensive air shower array is the high energy threshold which limits the horizon of the *** address this issue a new trigger method is developed in this article to lower the energy threshold of wCDA for GRB *** The proposed method significantly improves the detection efficiency of wCDA for gamma-rays around the GRB direction at 10-300 *** sensitivity of the wCDA for GRB detection with the new trigger method is *** achieved sensitivity of the quarter wCDA array above 10 GeV is comparable with that of *** data analysis process and corresponding fluence upper limit for GRB 190719C is presented as an example.

关键词： LHAASO wCDA GRB

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A dynamic range extension system for LHAASOwCDA-1

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Radiation Detection Technology and Methods 2021年第4期5卷 520-530页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi H.Cai j.T.Cai Z.Cao Z.Cao j.Chang j.F.Chang X.C.Chang B.M.Chen j.Chen L.Chen L.Chen L.Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu D.della Volpe B.D’Ettorre Piazzoli X.j.Dong j.H.Fan Y.Z.Fan Z.X.Fan j.Fang K.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao w.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He j.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang Q.L.Huang w.H.Huang X.T.Huang Y.Huang Z.C.Huang F.ji X.L.ji H.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li j.Li K.Li w.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood w.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng j.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wang C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wang R.N.wang w.wang w.wang X.G.wang X.j.wang X.Y.wang Y.D.wang Y.j.wang Y.P.wang Z.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang j.Y.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao j.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou j.N.Zhou Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics BeijingChina University of Science and Technology of China Hefei 230026AnhuiChina Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006GuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhai 519000GuangdongChina School of Physical Science and Technology Guangxi UniversityNanning 530004GuangxiChina Hebei Normal University Shijiazhuang 050024HebeiChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001HenanChina School of Astronomy and Space Science Nanjing UniversityNanjing 210023JiangsuChina Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023JiangsuChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237ShandongChina Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031SichuanChina College of Physics Sichuan UniversityChengdu 610065SichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000TibetChina School of Physics

Purpose The main scientific goal of LHAASO-wCDA is to survey gamma-ray sources with energy from 100 GeV to 30 *** observe high-energy shower events,especially to measure the energy spectrum of cosmic rays from 100 TeV to 10 PeV,a dynamic range extension system(wCDA++)is designed to use a 1.5-inch PMT with a dynamic range of four orders of magnitude for each cell in *** The dynamic range is extended by using these PMTs to measure the effective charge density in the core region of air shower events,which is an important parameter for identifying the composition of primary *** and Conclusion The system has been running for more than one *** this paper,the details of the design and performance of wCDA++are presented.

关键词： LHAASO-wCDA wCDA++ water Cherenkov detector Performance

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Prospects for a multi-TeV gamma-ray sky survey with the LHAASO water Cherenkov detector array

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Chinese Physics C 2020年第6期44卷 123-132页

作者： F.Aharonian V.Alekseenko Q.An Axikegu L.X.Bai Y.w.Bao D.Bastieri9 X.j.Bi H.Cai Zhe Cao Zhen Cao j.Chang j.F.Chang X.C.Chang S.P.Chao B.M.Chen j.Chen L.Chen L.Chen M.L.Chen M.j.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu B.D'Ettorre Piazzoli j.Fang j.H.Fan Y.Z.Fan C.F Feng L.Feng S.H.Feng Y.L.Feng B.Gao Q.Gao w.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He j.C.He M.Heller S.L.He Y.He C.Hou D.H.Huang Q.L.Huang w.H.Huang X.T.Huang H.B.Hu S.Hu H.Y.jia K.jiang F.ji C.jin X.L.ji K.Levochkin E.w.Liang Y.F Liang Cheng Li Cong Li F.Li H.Li H.B.Li H.C.Li H.M.Li j.Li K.Li w.L.Li X.Li X.R.Li Y.Li Z.Li Z.Li B.Liu C.Liu D.Liu H.D.Liu H.Liu j.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma j.R.Mao A.Masood X.H.Ma w.Mitthumsiri T.Montaruli Y.C.Nan P.Pattarakijwanich Z.Y.Pei B.Q.Qiao M.Y.Qi D.Ruffolo V.Rulev A.Sáiz L.Shao O.Shchegolev X.D.Sheng j.R.Shi Y.Stenkin V.Stepanov Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian D.D.Volpe C.wang H.wang H.G.wang j.C.wang L.Y.wang w.wang w.wang X.G.wang X.Y.wang X.j.wang Y.D.wang Y.j.wang Y.N.wang Y.P.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu G.M.Xiang G.Xiao G.G.Xin Y.Xing R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Q.Yuan Y.H.Yu Z.j.jiang H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang P.F.Zhang P.P.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Yi Zhang Yong Zhang Y.F.g Zhang B.Zhao j.Zhao L.Zhao L.Z.Zhao F.Zheng Y.Zheng j.N.Zhou P.Zhou R.Zhou X.X.Zhou C.G.Zhu F.R.Zhu H.Zhu K.j.Zhu X.Zuo Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduShichuanChina University of Science and Technology of China 230026 HefeiAnhuiChina Tsinghua University 100084 BeijingChina National Astronomical Observatories Chinese Academy of Sciences100101 BeijingChina National Space Science Center Chinese Academy of Sciences100190 BeijingChina School of Physics Peking University100871 BeijingChina Center for Astrophysics Guangzhou University510006 GuangzhouGuangdongChina Sun Yat-sen University 519000 ZhuhaiGuangdongChina Shool of Physics and Technology Guangxi University530004 NanningGuangxiChina Hebei Normal University 050024 ShijiazhuangHebeiChina School of Physics and Engineering Zhengzhou University450001 ZhengzhouHenanChina Nanjing University 210023 NanjingJiangsuChina Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of Sciences210034 NanjingJiangsuChina Institute of Frontier and Interdisciplinary Science Shandong University266237 QingdaoShandongChina Shanghai Astronomical Observatory Chinese Academy of Sciences200030 ShanghaiChina School of Physical Science and Technology Southwest Jiaotong University610031 ChengduSichuanChina Sichuan University 610065 ChengduSichuanChina Key Laboratory of Cosmic Rays(Tibet University) Ministry of Education850000 LhasaTibetChina School of physics and technology Wuhan university430072 WuhanChina Yunnan University 650091 KunmingYunnanChina Yunnan Astronomical Observatories Chinese Academy of Sciences650216 KunmingYunnanChina Institute for Nuclear Research Russian Academy of SciencesMoscowRussia Département de Physique Nucléaire et Corpusculaire Facultéde SciencesUniversitéde GenéveGenevaSwitzerland Department of Physics Faculty of ScienceMahidol UniversityBangkokThailand Dublin Institute for Advanced Studies 31 Fitzwilliam PlaceDublin 2Ireland Max-Planc

The water Cherenkov Detector Array(wCDA) is a major component of the Large High Altitude Air Shower Array Observatory(LHAASO), a new generation cosmic-ray experiment with unprecedented sensitivity, currently under construction. wCDA is aimed at the study of TeV γ-rays. In order to evaluate the prospects of searching for TeV γ-ray sources with wCDA, we present a projection of the one-year sensitivity of wCDA to TeV γ-ray sources from TeVCat using an all-sky approach. Out of 128 TeVCat sources observable by wCDA up to a zenith angle of 45°, we estimate that 42 would be detectable in one year of observations at a median energy of 1 TeV. Most of them are Galactic sources, and the extragalactic sources are Active Galactic Nuclei(AGN).

关键词： TeVγ-ray astronomy observational prospect LHAASO-wCDA

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Performance of LHAASO-wCDA and observation of the Crab Nebula as a standard candle

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Chinese Physics C 2021年第8期45卷 166-181页

作者： F.Aharonian Q.An Axikegu L.X.Bai Y.X.Bai Y.w.Bao D.Bastieri X.j.Bi Y.j.Bi H.Cai j.T.Cai Z.Cao Z.Cao j.Chang j.F.Chang X.C.Chang B.M.Chen j.Chen L.Chen L.Chen L.Chen M.j.Chen M.L.Chen Q.H.Chen S.H.Chen S.Z.Chen T.L.Chen X.L.Chen Y.Chen N.Cheng Y.D.Cheng S.w.Cui X.H.Cui Y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu D.della Volpe B.D'Ettorre Piazzoli X.j.Dong j.H.Fan Y.Z.Fan Z.X.Fan j.Fang K.Fang C.F.Feng L.Feng S.H.Feng Y.L.Feng B.Gao C.D.Gao Q.Gao w.Gao M.M.Ge L.S.Geng G.H.Gong Q.B.Gou M.H.Gu j.G.Guo X.L.Guo Y.Q.Guo Y.Y.Guo Y.A.Han H.H.He H.N.He j.C.He S.L.He X.B.He Y.He M.Heller Y.K.Hor C.Hou X.Hou H.B.Hu S.Hu S.C.Hu X.j.Hu D.H.Huang Q.L.Huang w.H.Huang X.T.Huang Z.C.Huang F.ji X.L.ji H.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.Levochkin B.B.Li C.Li C.Li F.Li H.B.Li H.C.Li H.Y.Li j.Li K.Li w.L.Li X.Li X.Li X.R.Li Y.Li Y.Z.Li Z.Li Z.Li E.w.Liang Y.F.Liang S.j.Lin B.Liu C.Liu D.Liu H.Liu H.D.Liu j.Liu j.L.Liu j.S.Liu j.Y.Liu M.Y.Liu R.Y.Liu S.M.Liu w.Liu Y.N.Liu Z.X.Liu w.j.long R.Lu H.K.Lv B.Q.Ma L.L.Ma X.H.Ma j.R.Mao A.Masood w.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi B.Q.Qiao D.Ruffolo V.Rulev A.Saiz L.Shao O.Shchegolev X.D.Sheng j.R.Shi H.C.Song Yu.V.Stenkin V.Stepanov Q.N.Sun X.N.Sun Z.B.Sun P.H.T.Tam Z.B.Tang w.w.Tian B.D.wang C.wang H.wang H.G.wang j.C.wang j.S.wang L.P.wang L.Y.wang R.N.wang w.wang w.wang X.G.wang X.j.wang X.Y.wang Y.D.wang Y.j.wang Y.P.wang Z.wang Z.wang Z.H.wang Z.X.wang D.M.wei j.j.wei Y.j.wei T.wen C.Y.wu H.R.wu S.wu w.X.wu X.F.wu S.Q.Xi j.Xia j.j.Xia G.M.Xiang G.Xiao H.B.Xiao G.G.Xin Y.L.Xin Y.Xing D.L.Xu R.X.Xu L.Xue D.H.Yan C.w.Yang F.F.Yang j.Y.Yang L.L.Yang M.j.Yang R.Z.Yang S.B.Yang Y.H.Yao Z.G.Yao Y.M.Ye L.Q.Yin N.Yin X.H.You Z.Y.You Y.H.Yu Q.Yuan H.D.Zeng T.X.Zeng w.Zeng Z.K.Zeng M.Zha X.X.Zhai B.B.Zhang H.M.Zhang H.Y.Zhang j.L.Zhang j.w.Zhang L.Zhang L.Zhang L.X.Zhang P.F.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang X.Zhang X.P.Zhang Y.Zhang Y.Zhang Y.F.Zhang Y.L.Zhang B.Zhao j.Zhao L.Zhao L.Z.Zhao S.P.Zhao F.Zheng Y.Zheng B.Zhou H.Zhou j.N.Zhou Key Laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduSichuanChina State Key Laboratory of Particle Detection and Electronics China University of Science and Technology of China Hefei 230026China Department of Engineering Physics Tsinghua UniversityBeijing 100084China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Space Science Center Chinese Academy of SciencesBeijing 100190China School of Physics Peking UniversityBeijing 100871China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen UniversityZhuhai 519082China School of Physical Science and Technology Guangxi UniversityNanning 530004China Hebei Normal University Shijiazhuang 050024China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China College of Physics Sichuan UniversityChengdu 610065China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan University

The first water Cherenkov detector of the LHAASO experiment(wCDA-1)has been operating since April *** data for the first year have been analyzed to test its performance by observing the Crab Nebula as a standard *** wCDA-1 achieves a sensitivity of 65 mCU per year,with a statistical threshold of 5 *** accomplish this,a 97.7%cosmic-ray background rejection rate around 1 TeV and 99.8%around 6 TeV with an ap proximate photon acceptance of 50%is achieved after applying an algorithm to separate gamma-induced *** angular resolution is measured using the Crab Nebula as a point source to be approximately 0.45°at 1 TeV and better than 0.2°above 6 TeV,with a pointing accuracy better than 0.05°.These values all match the design *** energy resolution is found to be 33%for gamma rays around 6 *** spectral energy distribution of the Crab Nebula in the range from 500 GeV to 15.8 TeV is measured and found to be in agreement with the results from other TeV gamma ray observatories.

关键词： LHAASO-wCDA Crab Nebula angular resolution spectral energy distribution

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MoS_(2)Lubricate‑Toughened MXene/ANF Composites for Multifunctional Electromagnetic Interference Shielding

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Nano-Micro Letters 2025年第2期17卷 358-371页

作者： jiaen wang wei Ming longfu Chen Tianliang Song Moxi Yele Hao Zhang long Yang Gegen Sarula Benliang Liang Luting Yan Guangsheng wang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing 100044People’s Republic of China Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

The design and fabrication of high toughness electromagnetic interference(EMI)shielding composite films with diminished reflection are an imperative task to solve electromagnetic pollution *** MXene/ANF(aramid nanofibers)–MoS_(2)composite films with nacre-like layered structure here are fabricated after the introduction of MoS_(2)into binary MXene/ANF composite *** introduction of MoS_(2)fulfills an impressive“kill three birds with one stone”improvement effect:lubrication toughening mechanical performance,reduction in secondary reflection pollution of electromagnetic wave,and improvement in the performance of photothermal *** the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 50:50),the strain to failure and tensile strength increase from 22.1±1.7%and 105.7±6.4 MPa and to 25.8±0.7%and 167.3±9.1 MPa,*** toughness elevates from 13.0±4.1 to 26.3±0.8 Mj m^(−3)(~102.3%)*** the reflection shielding effectiveness(SE_(R))of MXene/ANF(mass ratio of 50:50)decreases~10.8%.EMI shielding effectiveness(EMI SE)elevates to 41.0 dB(8.2–12.4 GHz);After the introduction of MoS_(2)into binary MXene/ANF(mass ratio of 60:40),the strain to failure increases from 18.3±1.9%to 28.1±0.7%(~53.5%),the SE_(R)decreases~22.2%,and the corresponding EMI SE is 43.9 *** MoS_(2)also leads to a more efficient photothermal conversion performance(~45 to~55℃).Additionally,MXene/ANF–MoS_(2)composite films exhibit excellent electric heating performance,quick temperature elevation(15 s),excellent cycle stability(2,2.5,and 3 V),and long-term stability(2520 s).Combining with excellent mechanical performance with high MXene content,electric heating performance,and photothermal conversion performance,EMI shielding ternary MXene/ANF–MoS_(2)composite films could be applied in many industrial *** work broadens how to achieve a balance between mechanical properties and versatility of composites in the case of high-function fillers.

关键词： MXene-MoS_(2) Lubrication toughening EMI shielding Photothermal conversion Electric heating performance

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Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo

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Neural Regeneration Research 2025年第9期20卷 2633-2644页

作者： Zhimin long Chuanhua Ge Yueyang Zhao Yuanjie Liu Qinghua Zeng Qing Tang Zhifang Dong Guiqiong He Institute of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqingChina Department of Anatomy Chongqing Medical UniversityChongqingChina Department of Physiology Chongqing Medical UniversityChongqingChina Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina National Clinical Research Center for Child Health and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque ***,resto ring normal lysosomal function and rebalancing lysosomal acidification in neurons in the brain may be a new treatment strategy for Alzheimer's *** acetylation/deacetylation plays a central role in lysosomal ***,we show that inhibiting the classic microtubule deacetylase histone deacetylase 6 with an histone deacetylase 6 shRNA or thehistone deacetylase 6 inhibitor valproic acid promoted lysosomal reacidification by modulating V-ATPase assembly in Alzheimer's *** rthermore,we found that treatment with valproic acid markedly enhanced *** clearance of amyloid-βaggregates,and ameliorated cognitive deficits in a mouse model of Alzheimer's *** findings demonstrate a previously unknown neuroprotective mechanism in Alzheimer's disease,in which histone deacetylase 6 inhibition by valproic acid increases V-ATPase assembly and lysosomal acidification.

关键词： Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPase

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