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Role of diffusion-w.ighted magnetic resonance imaging in the differential diagnosis of focal hepatic lesions

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world Journal of Gastroenterology 2009年第46期15卷 5805-5812页

作者： Naoto koike Akihiro Cho katsuhiro Nasu kazuhiko seto Shigeyuki Nagaya yuji Ohshima Nobuhiro Ohkohchi Department of Surgery Seirei Sakura Citizen Hospital Department of Surgery Chiba Cancer Center Department of Radiology Institute of Clinical MedicineUniversity of Tsukuba Department of Radiology Seirei Sakura Citizen Hospital Department of Radiology Seirei Mikatabara Hospital Department of Surgery Institute of Clinical MedicineUniversity of Tsukuba

AiM： To evaluate the utility of diffusion-w.ighted imaging （Dwl） in screening and differential diagnosis of benign and malignant focal hepatic lesions. METHODS： Magnetic resonance imaging （MRi） examinations were performed using the Signa Excite Xl Twin Speed 1.5T system （GE Healthcare, Milwaukee, wl, USA）. Seventy patients who had undergone MRi of the liver [29 hepatocellular carcinomas （HCC）, four cholangiocarcinomas, 34 metastatic liver cancers, 10 hemangiomas, and eight cysts] between April 2004 and August 2008 were retrospectively evaluated. Visualization of lesions, relative contrast ratio （RCR）, and apparent diffusion coefficient （ADC） were compared between benign and malignant lesions on Dwl. Su- perparamagnetic iron oxide （SPiO） was administered to 59 patients, and RCR was compared pre- and ***： Dwi showed higher contrast between malignant lesions （especially in multiple small metastatic cancers） and surrounding liver parenchyma than did contrast-enhanced computed tomography. ADCs （mean±SD × 10^-3 mm2/s） were significantly lower （P 〈 0.05） in malignant lesions （HCC： 1.31 ± 0.28 and liver metastasis： 1.11 ± 0.22） and were significantly higher in benign lesions （hemangioma： 1.84 ± 0.37 and cyst： 2.61 ± 0.45） than in the surrounding hepatic tissues. RCR between malignant lesions and surrounding he- patic tissues significantly improved after SPiO administration, but RCRs in benign lesions were not ***： Dwi is a simple and sensitive method for screening focal hepatic lesions and is useful for differential diagnosis.

关键词： Hepatic tumor Liver imaging Magneticresonance imaging Diffusion-w.ighted imaging Apparent diffusion coefficient

Serological diagnosis of nasopharyngeal carcinoma by enzyme linked immunosorbant assay:optimization,standardization and diagnostic criteria

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Chinese Medical Journal 1998年第6期 51-56页

作者： M.H. Ng, H.L. Chen, R.X. Luo, k.H. Chan, P.C.y. woo, J.S.T. Sham, J. Huang, w.H.seto P. Smith and B.E. Griffin

Objectives To produce an enzyme linked immunosorbant assay (ELiSA) to detect antibodies against Epstein Barr virus (EBV) specified nuclear antigen 1 (EBNA 1) and the 18kD EBV matrix protein, and to determine and optimize its sensitivity and specificity for the diagnosis of nasopharyngeal carcinoma (NPC).Methods we used a combination of highly purified glutathione transferase fusion proteins of the 40kD carboxy domain of EBNA1 and the 18kD EBV matrix protein for coating ELiSA plates. in three separate studies, we tested for igA antibodies in serum specimens from 28 EBV seronegative donors, 284 EBV seropositive donors and 160 newly diagnosed NPC patients. By comparing the sensitivity and specificity of diagnosis obtained for different cutoff values, we derived several quantitative parameters to evaluate assay performance, establish objective diagnostic criteria w.ich optimize the intrinsic diagnostic capability of the assay and assess the significance of individual test results, respectively. Optimum cutoff optical density (OD) is defined as the cutoff OD where sensitivity of the assay equals its specificity, and resolution of the assay is indicated by the value of sensitivity (or specificity) determined at the optimum cutoff OD. Diagnosis of NPC was achieved by setting a cutoff zone at +/-20% of this *** All the EBV seronegative donors tested were not reactive, and most of the EBV seropositive donors were weak.y reactive, w.ile the majority of NPC patients were moderately or strongly reactive. w.ile the assay was thus shown to be specific for EBV, there was an overlap in the level of these serum antibodies between few.individuals of the two latter groups. it was shown that the assay performed equally well in two separate studies conducted under different testing conditions and using different collections of sera in that assay resolution determined on these occasions were 86% and 87% respectively. Diagnosis of NPC can be achieved at the same expected sensiti

关键词： Serological diagnosis of nasopharyngeal carcinoma by enzyme linked immunosorbant assay

Proteomic identification and functional characterization of MyH9, Hsc70, and DNAJA1 as novel substrates of HDAC6 deacetylase activity

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Protein & Cell 2015年第1期6卷 42-54页

作者： Linlin Zhang Shanshan Liu Ningning Liu yong Zhang Min Liu Dengwen Li Edward seto Tso-Pangyao wenqing Shui J-un Zhou State k.y Laboratory of Medicinal Chemical Biology College of Life Sciences Nankai University Tianjin 300071 China High-throughput Molecular Drug Discovery Center Tianjin Joint Academy of Biotechnology and Medicine Tianjin 300457 China Molecular Oncology Program H. Lee Moffitt Cancer Center and Research Institute Tampa FL 33612 USA Department of Pharmacology and Cancer Biology Duke University Durham NC 27710 USA

Histone deacetylase 6 （HDAC6）, a predominantly cyto- plasmic protein deacetylase, participates in a wide range of cellular processes through its deacetylase activity. However, the diverse functions of HDAC6 can- not be fully elucidated with its known substrates. in an attempt to explore the substrate diversity of HDAC6, we performed quantitative proteomic analyses to monitor changes in the abundance of protein lysine acetylation in response to HDAC6 deficiency. we identified 107 proteins with elevated acetylation in the liver of HDAC6 knockout mice. Three cytoplasmic proteins, including myosin heavy chain 9 （MyH9）, heat shock cognate pro- tein 70 （HscT0）, and dnaJ homolog subfamily A member 1 （DNAJA1）, were verified to interact with HDAC6. The acetylation levels of these proteins were negatively regulated by HDAC6 both in the mouse liver and in cultured cells. Functional studies reveal that HDAC6- mediated deacetylation modulates the actin-binding ability of MyH9 and the interaction between Hsc70 and DNAJA1. These findings consolidate the notion that HDAC6 serves as a critical regulator of proteinacetylation with the capability of coordinating various cellular functions.

关键词： HDAC6 substrate lysine acetylation,quantitative proteomics interaction

Early-diverging fungal phyla:taxonomy,species concept,ecology,distribution,anthropogenic impact,and novel phylogenetic proposals

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Fungal Diversity 2021年第4期109卷 59-98页

作者： kerstin Voigt Timothy y.James Paul M.kirk AndréL.C.M.de A.Santiago Bruce waldman Gareth w.Griffith Minjie Fu Renate Radek Jürgen F.H.Strassert Christian wurzbacher Gustavo Henrique Jerônimo David R.Simmons kensuke seto Eleni Gentekaki Vedprakash G.Hurdeal kevin D.Hyde Thuong T.T.Nguyen Hyang Burm Lee Jena Microbial Resource Collection Leibniz Institute for Natural Product Research and Infection BiologyAdolf-Reichwein-Straße 2307745 JenaGermany institute of Microbiology Faculty of Biological SciencesFriedrich Schiller University JenaNeugasse 2507743 JenaGermany Department of Ecology and Evolutionary Biology University of MichiganAnn ArborMI 48109USA Biodiversity informatics and Spatial Analysis Jodrell LaboratoryRoyal Botanic Gardens KewSurrey TW93DSUK Department of Mycology Federal University of PernambucoAv.Da Engenharias/nRecifePE 50740-4600Brazil School of Biological Sciences Seoul National UniversitySeoul 08826South Korea Department of integrative Biology Oklahoma State UniversityStillwaterOK 74078USA institute of Biological Environmentaland Rural Sciences(IBERS)Aberystwyth UniversityAberystwyth SY233DDWalesUK institute of Biology/Zoology Evolutionary BiologyFreie Universität Berlin14195 BerlinGermany Leibniz institute of Freshwater Ecology and inland Fisheries Ecosystem Research12587 BerlinGermany Department of Civil Geo and Environmental EngineeringTechnical University of MunichGarchingGermany School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand Environmental Microbiology Lab Department of Agricultural Biological ChemistryCollege of Agriculture&Life SciencesChonnam National UniversityGwangju 61186South Korea

The increasing number of new fungal species described from all over the world along with the use of genetics to define taxa,has dramatically changed the classification system of early-diverging fungi over the past several *** number of phyla established for non-Dikarya fungi has increased from 2 to ***,to date,both the classification and phylogeny of the basal fungi are still *** this article,we review the recent taxonomy of the basal fungi and re-evaluate the relationships among early-diverging lineages of fungal *** also provide information on the ecology and distribu-tion in Mucoromycota and highlight the impact of chytrids on amphibian *** concepts in Chytridiomycota,Aphelidiomycota,Rozellomycota,Neocallimastigomycota are discussed in this *** preserve the current application of the genus Nephridiophaga(Chytridiomycota:Nephridiophagales),a new type species,Nephridiophaga blattellae,is proposed.

关键词： Early-diverging fungi Evolution Nuclear large subunit(LSU/28S) Nuclear small subunit(SSU/18S) Molecular phylogeny

Methods for a blind analysis of isobar data collected by the STAR collaboration

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Nuclear Science and Techniques 2021年第5期32卷 43-50页

作者： J.Adam L.Adamczyk J.R.Adams J.k.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed i.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi k.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland i.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderon de la Barca Sanchez D.Cebra i.Chakaberia P.Chaloupka B.k.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury w.Christie X.Chu H.J.Crawford M.Csanad M.Daugherity T.G.Dedovich i.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng y.Feng P.Filip E.Finch y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson k.Gopal X.Gou D.Grosnick w.Guryn A.i.Hamad A.Hamed S.Harabasz J.w.Harris S.He w.He X.H.He y.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub y.Hong S.Horvat y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.igo D.isenhower w.w.Jacobs C.Jena A.Jentsch y.Ji J.Jia k.Jiang S.Jowzaee X.Ju E.G.Judd S.kabana M.L.kabir S.kagamaster D.kalinkin k.kang D.kapukchyan k.kauder H.w.ke D.keane A.kechechyan M.kelsey y.V.k.yzhniak D.P.kikoła C.kim B.kimelman D.kincses T.A.kinghorn i.kisel A.kiselev M.kocan L.kochenda L.k.kosarzewski L.kramarik P.kravtsov k.krueger N.kulathunga Mudiyanselage L.kumar S.kumar R.kunnawalkam Elayavalli J.H.kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee y.H.Leung C.Li C.Li w.Li w.Li X.Li y.Li y.Liang R.Licenik T.Lin y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu y.Liu Z.Liu T.Ljubicic w.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty i.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Md.Nasim k.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonak Christian University AbileneTX 796992 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov institute for Theoretical and Experimental Physics NRC"kurchatov institute" MoscowRussia 117218 Argonne National Laboratory ArgonneIL 60439 American University of Cairo New CairoNew Cairo 11835Egypt Brookhaven National Laboratory UptonNY 11973 University of California BerkeleyCA 94720 University of California DavisCA 95616 University of California Los AngelesCA 90095 University of California RiversideCA 92521 Central China Normal University Wuhan 430079 University of illinois at Chicago ChicagoIL 60607 Creighton University OmahaNE 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universitat Darmstadt Darmstadt 64289Germany ELTE Eotvos Lorand University Budapest 1117Hungary Frankfurt institute for Advanced Studies FiAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg 69120 HeidelbergGermany University of Houston HoustonTX 77204 Huzhou University Huzhou 313000 indian institute of Science Education and Research(iiSER) Berhampur 760010India indian institute of Science Education and Research(iiSER)Tirupati Tirupati 517507India indian institute Technology PatnaBihar 801106India indiana University BloomingtonIN 47408 institute of Modern Physics Chinese Academy of SciencesLanzhou 730000 University of Jammu Jammu 180001India Joint institute for Nuclear Research DubnaRussia 141980 kent State University KentOH 44242 University of kentucky LexingtonKY 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCA 94720 Lehigh University BethlehemPA 18015 Max-Planck-institut fur Physik 80805 MunichGermany Michigan State University East LansingMI 48824 National Research Nuclear University MEPhi MoscowRussia 115409 National institute of Science Education and Research HBNIJatni 752050India National Cheng kung University Tainan 70101 Nuclear Physics institute of the CAS Rez 25068Czech Republic Ohio State University

in 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of *** isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)*** order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis *** are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of w.ich respects time-dependent changes in run *** tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking *** this sample,species-specific information is disguised,but individual output files contain data from a single isobar *** run-by-run corrections and code alteration subsequent to these corrections are allowed at this *** these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind *** a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in *** Au+Au data were prepared in the same manner intended for the isobar blind *** details of the blind analysis procedure and results from the mock data challenge are presented.

关键词： Blind analysis Chiral magnetic effect Heavy-ion collisions

Measurement of away-side broadening with self-subtraction of flow.in Au+Au collisions at √sNN=200 GeV

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Chinese Physics C 2020年第10期44卷 59-67页

作者： L.Adamczyk J.R.Adams J.k.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed i.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi k.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland i.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderón de la Barca Sánchez D.Cebra i.Chakaberia P.Chaloupka B.k.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury w.Christie X.Chu H.J.Crawford M.Csanád M.Daugherity T.G.Dedovich i.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng y.Feng P.Filip E.Finch y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson k.Gopal D.Grosnick w.Guryn A.i.Hamad A.Hamed S.Harabasz J.w.Harris S.He w.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub y.Hong S.Horvat y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.igo D.isenhower w.w.Jacobs C.Jena A.Jentsch y.Ji J.Jia k.Jiang S.Jowzaee X.Ju E.G.Judd S.kabana M.L.kabir S.kagamaster D.kalinkin k.kang D.kapukchyan k.kauder H.w.ke D.keane A.kechechyan M.kelsey y.V.k.yzhniak D.P.kikoła C.kim B.kimelman D.kincses T.A.kinghorn i.kisel A.kiselev M.kocan L.kochenda L.k.kosarzewski L.kramarik P.kravtsov k.krueger N.kulathunga Mudiyanselage L.kumar S.kumar R.kunnawalkam Elayavalli J.H.kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee y.H.Leung C.Li w.Li w.Li X.Li y.Li y.Liang R.Licenik T.Lin y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu y.Liu Z.Liu T.Ljubicic w.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty i.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Nasim Md k.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa Abilene Christian University AbileneTexas 79699 AGH University of Science and Technology FPACSCracow 30-059Poland Alikhanov institute for Theoretical and Experimental Physics NRC"kurchatov institute" Moscow 117218Russia Argonne National Laboratory ArgonneIllinois 60439 American University of Cairo New Cairo 11835New CairoEgypt Brookhaven National Laboratory UptonNew York 11973 University of California BerkeleyCalifornia 94720 University of California DavisCalifornia 95616 University of California Los AngelesCalifornia 90095 University of California RiversideCalifornia 92521 Central China Normal University WuhanHubei 430079 University of illinois at Chicago ChicagoIllinois 60607 Creighton University OmahaNebraska 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universität Darmstadt Darmstadt 64289Germany ELTE Eötvös Loránd University BudapestHungary H-1117 Frankfurt institute for Advanced Studies FiAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg Heidelberg 69120Germany University of Houston HoustonTexas 77204 Huzhou University HuzhouZhejiang 313000 indian institute of Science Education and Research(iiSER) Berhampur 760010India indian institute of Science Education and Research(iiSER)Tirupati Tirupati 517507India indian institute Technology PatnaBihar 801106India indiana University BloomingtonIndiana 47408 institute of Modern Physics Chinese Academy of SciencesLanzhouGansu 730000 University of Jammu Jammu 180001India Joint institute for Nuclear Research Dubna 141980Russia kent State University KentOhio 44242 University of kentucky LexingtonKentucky 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Lehigh University BethlehemPennsylvania 18015 Max-Planck-institut für Physik Munich 80805Germany Michigan State University East LansingMichigan 48824 National Research Nuclear University MEPhi Moscow 115409Russia National institute of Science Education and Research HBNIJatni 752050Indi

High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion *** of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic *** report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR *** correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5istent with Gaussians,and their widths increase with *** results indicate jet broadening in the medium created in central heavy-ion collisions.

关键词： di-hadron correlations jet heavy-ion

M(o|¨)ssbauer Spectroscopic Study of Fe-Oxipnictide Superconductors

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M(o|¨)ssbauer Spectroscopic Study of Fe-Oxipnictide Superco...

读柳敏荣《韩国戏剧运动史》——从日本的中国戏剧研究者的眼光看

作者： S.kitao y.kobayashi M.kurokuzu M.Saito y.kamihara M.Hirano T.Mitsui H.Hosono M.seto Research Reactor institute Kyoto University CREST Japan Science and Technology Agency ERA TO-SORST Japan Science and Technology Agency Tokyo institute of Technology Japan Atomic Energy Agency ERATO-SORST Japan Science and Technology Agency

iNTRODUCTiON:Recently,kamihara et *** a new series of superconductors in Fe-oxipnictides LaFePO and,successively,F-doped LaFeAsOF with the transition temperature(To) of 26 *** magnetic elements,such as Fe,had been thought to be incompatible with the emergence of superconductivity, these reports surprised many researchers and have brought extensive following ***, first-principles calculations for the Fe-oxipnictides showed that the 3d-bands of Fe are primary components

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首都师范大学学报（社会科学版） 2021年第6期 146-153页

作者： [日]濑户宏() 郭艳平(译) 早稻田大学演剧博物馆北京理工大学珠海学院广东珠海519085

柳敏荣著,津川泉译的《韩国戏剧运动史》,是一部讲述20世纪初韩国近现代戏剧从起源到现在超过百年历史的通史。原著于2001年出版,为了配合日文版的发行,作者进行了补遗。本书的内容由"第一部开化期和传统表演艺术""第二部日本新派剧的... 详细信息

柳敏荣著,津川泉译的《韩国戏剧运动史》,是一部讲述20世纪初韩国近现代戏剧从起源到现在超过百年历史的通史。原著于2001年出版,为了配合日文版的发行,作者进行了补遗。本书的内容由"第一部开化期和传统表演艺术""第二部日本新派剧的流入及其本土化""第三部民族自觉和民众戏剧""第四部黑暗和混沌的戏剧""第五部战争和戏剧基础的崩塌""第六部戏剧再建之重重险路""第七部产业社会和戏剧多样化""结尾""《韩国戏剧运动史》补遗"构成,并且附有译者笔记——日本人眼中的朝鲜殖民地的戏剧界、译者后记、参考文献、《韩国戏剧运动史》简年表、照片及索引。笔者从研究中国戏剧的日本人的眼光通读本书,以评论者的视角指出韩国近现代戏剧的问题。

关键词：柳敏荣《韩国戏剧运动史》唱剧韩国新派韩国新剧

HER-2阳性胃癌对曲妥珠单抗为基础化疗的病理反应

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临床与实验病理学杂志 2017年第5期33卷 510-510页

作者： Urabe M Ushiku T seto y Fuk.yama M 黄爱清余英豪不详解放军福州总医院病理科福州350025

以曲妥珠单抗为基础的化疗是目前治疗HER-2阳性晚期胃癌的标准方法，能有效延长晚期HER-2阳性胃癌患者总生存期和无进展生存率。由于手术标本较少，HER-2阳性胃癌曲妥珠单抗治疗后的组织病理学变化迄今尚未阐明。作者旨在描述HER-2阳性... 详细信息

以曲妥珠单抗为基础的化疗是目前治疗HER-2阳性晚期胃癌的标准方法，能有效延长晚期HER-2阳性胃癌患者总生存期和无进展生存率。由于手术标本较少，HER-2阳性胃癌曲妥珠单抗治疗后的组织病理学变化迄今尚未阐明。作者旨在描述HER-2阳性胃癌曲妥珠单抗治疗后胃癌组织反应及其与HER-2状态的相关性。

关键词： HER-2阳性曲妥珠单抗晚期胃癌病理反应化疗单抗治疗组织反应病理学变化