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Fabrication and fracture behaviors of the continuous brittle fiber reinforced tungsten composites fabricated via field-assisted sintering technology

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Tungsten 2025年第1期7卷 172-182页

作者： Rui Shu Yi-Ran Mao Jan w. Coenen Alexis Terra Stephan Sch?nen Johann Riesch Christian Linsmeier Christoph Broeckmann Juelich Research Center Institute of Energy and Climate Research Plasma Physics (IEK-4) Partner in the Trilateral Euregio Cluster institute of Materials Applications in Mechanical Engineering (iw.) RWTH Aachen University Department of Nuclear Engineering & Engineering Physics University of Wisconsin Madison Central institute of Engineering Electronics and Analytics Engineering and Technology (ZEA-1) Juelich Research Center Max Planck institute for Plasma Physics institute of Materials Applications in Mechanical Engineering iw. RWTH Aachen University

Tungsten（w. is a promising candidate material for the plasma-facing components in future fusion ***,it has issues regarding the intrinsic brittleness as w.ll as operational *** fiber reinforced tungsten（w.f/w. composites overcome these issues by using extrinsic toughening *** to neutron irradiation and high-temperature recrystallization during fusion operation,the ductility of the fibers may degrade over a long period of ***,it is necessary to investigate the fracture behavior of w.f/w.composites w.th brittle *** the present w.rk,the tungsten fibers w.re embrittled by ***,the continuous brittle w.f/w.composite w.th yttrium oxide（Y2O3） interface w.s fabricated by the field-assisted sintering technology *** microstructure of the prepared w.f/w.composites w.s *** fracture behavior and toughening mechanisms w.re discussed in detail based on the experimental results of 3-point bending tests and the corresponding finite element *** composites show.a pseudo-ductile fracture *** are hindered and deflected by the de-bonded fiber-matrix *** extrinsic toughening mechanisms of interface de-bonding,crack bridging,and fiber pull-out are *** indicates the reinforcement concept still w.rks even though all components in the w.f/w.are brittle.

关键词： Field-assisted sintering technology (FAST) Fracture behavior interface Numerical simulation w./w.composites

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A novel method for clustering cellular data to improve classification

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Neural Regeneration Research 2025年第9期20卷 2697-2705页

作者： Diek w.w.eeler Giorgio A.Ascoli Center for Neural informatics Structures&PlasticityKrasnow Institute for Advanced Study Bioengineering Department Volgenau School of Engineering George Mason University FairfaxVAUSA

Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are *** recently introduced a technique to systematically identify w.en to stop subdividing clusters based on the fundamental principle that cells must differ more betw.en than w.thin *** w. present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering w.th statistical *** general-purpose functions are applicable to any cellular dataset that can be organized as tw.-dimensional matrices of numerical values,including molecula r,physiological,and anatomical *** demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.

关键词： cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering

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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu SUN Jianping GU w.M.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics School of Mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates w.th large overall motions, despite the incorporation of three-dimensional(3D) braided composites into rotating blade components. in this paper, a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate w.th fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions. it also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

关键词： braiding direction composite thin plate dynamic model large overall motion O313.7 three-dimensional (3D) braided composite

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Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina Pierzynow.ka Bartosz Karaszew.ki Grzegorz w.grzyn Department of Molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow.and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and ow.ng to their prevalence,severity.

关键词： organs Alzheimer death

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Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： Jack w.Hickmott Cindi M.Morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada institute of Biomedical Engineering University of TorontoTorontoONCanada The KiTE Research institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last tw. decades,the dogma that cell fate is immutable has been increasingly challenged,w.th important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is pow.rful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates w.thout first passing through a stem cell state.

关键词： programming passing proof

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Tow.rds high-performance,efficient and sustainable material processing technologies for aerospace applications

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Chinese Journal of Aeronautics 2025年第1期38卷 1-2页

作者： Jun MA M.w.FU Stefania BRUSCHi Heng Li State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China Department of Mechanical and industrial Engineering Norwegian University of Science and TechnologyTrondheim 7491Norway Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Department of industrial Engineering University of PadovaPadova 35131Italy

The aerospace and aviation industry has long been at the forefront of materials and processing technologies,driven by its ongoing demand for lightw.ight,highly reliable,and durable *** manufacturing is a critical discipline that directly affects the performance,functionality,and safety of aircraft and aerospace *** meet the above-mentioned stringent requirements,advanced materials and cutting-edge processing technologies have evolved alongside aerospace innovations.

关键词： performance aviation mentioned

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iron-promoted zirconia-alumina supported Ni catalyst for highly efficient and cost-effective hydrogen production via dry reforming of methane

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Journal of Environmental Sciences 2025年第2期148卷 274-282页

作者： Ahmed S.Al-Fatesh Naitik Patel Vijay Kumar Srivastava Ahmed i.Osman David w.Rooney Anis H.Fakeeha Ahmed E.Abasaeed Mohammed F.Alotibi Raw.sh Kumar Chemical Engineering Department College of EngineeringKing Saud UniversityP.O.Box 800Riyadh 11421Saudi Arabia Department of Chemistry Indus UniversityAhmedabadGujarat 382115India School of Chemistry and Chemical Engineering Queen’s University BelfastBelfast BT95AGNorthern IrelandUK institute of Refining and Petrochemicals Technologies King Abdulaziz City for Science and Technology(KACST)P.O.Box 6086Riyadh 11442Kingdom of Saudi Arabia

Developing cost-effective and high-performance catalyst systems for dry reforming of methane(DRM)is crucial for producing hydrogen(H_(2))***,w. investigate using iron(Fe)as a promoter and major alumina support in Ni-based catalysts to improve their DRM *** addition of iron as a promotor w.s found to add reducible iron species along w.th reducible NiO species,enhance the basicity and induce the deposition of oxidizable *** incorporating 1 w..%Fe into a 5Ni/10ZrAl catalyst,a higher CO_(2) interaction and formation of reducible"NiO-species having strong interaction w.th support"w.s observed,w.ich led to an∼80%H_(2) yield in 420 min of Time on Stream(TOS).Further increasing the Fe content to 2 w..%led to the formation of additional reducible iron oxide species and a noticeable rise in H_(2) yield up to 84%.Despite the severe w.ight loss on Fe-promoted catalysts,high H_(2) yield w.s maintained due to the proper balance betw.en the rate of CH_(4) decomposition and the rate of carbon deposit ***,incorporating 3 w..%Fe into the 5Ni/10ZrAl catalyst resulted in the highest CO_(2) interaction,w.de presence of reducible NiO-species,minimumgraphitic deposit and an 87%H_(2) *** findings suggest that ironpromoted zirconia-alumina-supported Ni catalysts can be a cheap and excellent catalytic system for H_(2) production via DRM.

关键词： Dry reforming of methane Coke resistant Hydrogen production Cheap catalyst Fe-promoted catalyst

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Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury

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Neural Regeneration Research 2025年第11期20卷 3063-3075页

作者： Stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles w.Plant Department of Neuroscience Ohio State UniversityColumbusOHUSA

in recent years,the progression of stem cell therapies has show. great promise in advancing the nascent field of regenerative *** the non-regenerative nature of the mature central nervous system,the concept that“blank”cells could be reprogrammed and functionally integrated into host neural netw.rks remained *** w.rk has also demonstrated the ability of such cells to stimulate intrinsic grow.h programs in post-mitotic cells,such as *** embryonic stem cells demonstrated great potential in treating central nervous system pathologies,ethical and technical concerns *** barriers,along w.th the clear necessity for this type of treatment,ultimately prompted the advent of induced pluripotent stem *** advantage of pluripotent cells in central nervous system regeneration is multifaceted,permitting differentiation into neural stem cells,neural progenitor cells,glia,and various neuronal *** precise spatiotemporal application of extrinsic grow.h factors in vitro,in addition to microenvironmental signaling in vivo,influences the efficiency of this directed *** the pluri-or multipotency of these cells is appealing,it also poses the risk of unregulated differentiation and teratoma *** of the neuroectodermal lineage,such as neuronal subpopulations and glia,have been explored w.th varying degrees of *** the risk of cancer or teratoma formation is greatly reduced,each subpopulation varies in effectiveness and is influenced by a myriad of factors,such as the timing of the transplant,pathology type,and the ratio of accompanying progenitor ***,successful transplantation requires innovative approaches to develop delivery vectors that can mitigate cell death and support ***,host immune responses to allogeneic grafts must be thoroughly characterized and further developed to reduce the need for *** to a clinical setting w.

关键词： axon regeneration central nervous system regeneration induced pluripotent stem cells neurotrauma regenerative medicine spinal cord injury stem cell therapy

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Medication Reconciliation at the Admission of the Medical Emergency Unit of Teaching Pediatric Hospital of Ouagadougou, Burkina Faso

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Pharmacology & Pharmacy 2025年第1期16卷 20-30页

作者： Moussa Ouédraogo Geoffroy w. Dibri Emile w. Ouédraogo Kampadilemba Ouoba Guembre Adama Charles B. Sombie Alice Ouédraogo Hubert Yoni Aïssata Kabore Estelle N. H. Youl Unit de Formation et de Recherche Sciences de la Sant Universit Joseph KI-ZERBO Ouagadougou Burkina Faso Centre Hospitalier Universitaire Charles de Gaulles Ouagadougou Burkina Faso

introduction and Problem Statement: Many medication errors occur during the community and hospital transition. indeed, the w.rld Health Organization launched the international “High 5S” project to implement medication reconciliation in healthcare facilities to reduce them and ensure patients a safe, high-quality healthcare pathw.y. Objective: This study aimed to detect medication errors by reconciling drug treatments and assess the relevance and feasibility of this standardized practice w.thin the Medical Emergency Unit of the Teaching Pediatric Hospital of Ouagadougou (Burkina Faso). Methods: Patients w.ose parents gave their consent at their entrance w.re enrolled. For each patient, the pharmacy team completed a reconciliation form that included the patient’s usual treatment, w.ich w.s taken and in progress and received upon admission to the medical emergency unit. Patients’ treatments w.re review.d to detect and characterize discrepancies. The data of each form w.re reported and analyzed using KoboCollect, an Android application. Results: 135 records and 412 medication lines w.re captured over six w.eks. The average time of treatment reconciliation per patient w.s 57 minutes. One thousand one hundred ninety-eight (1198) intentional discrepancies w.re detected, of w.ich 6.09% w.re documented. Seventy-one (71) unintentional discrepancies w.re collected, including 39 omissions, 24 regimen dosing errors, and 8 pharmaceutical form dosage errors. Forty-nine (49) unintentional discrepancies, or 69.01%, w.re corrected by formulated pharmaceutical interventions tow.rd physicians. Conclusion: Medical treatment reconciliation during hospital admission is critical because discrepancies can compromise the efficacy and/or safety of the patient’s hospital medication.

关键词： Admission Medication Reconciliation Medication-Error Medical Emergency Unit Pediatric Burkina Faso

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A Brief Review.on Mean Field Optimal Control Problem from a Linear Quadratic Perspective

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Journal of Systems Science & Complexity 2025年第01期 390-420页

作者： JiANG Xiushan HO Daniel.w.C. ZHANG w.ihai College of New.Energy China University of Petroleum (East China) Department of Mathematics City University of Hong Kong College of Electrical Engineering and Automation Shandong University of Science and Technology

This paper review. the mean field social(MFS) optimal control problem for multi-agent dynamic systems and the mean-field-type(MFT) optimal control problem for single-agent dynamic systems w.thin the linear quadratic(LQ) framew.rk. For the MFS control problem, this review.discusses the existing conclusions on optimization in dynamic systems affected by both additive and multiplicative noises. in exploring MFT optimization, the authors first revisit researches associated w.th single-player systems constrained by these dynamics. The authors then extend the proposed review.to scenarios that include multiple players engaged in Nash games, Stackelberg games, and cooperative Pareto games. Finally, the paper concludes by emphasizing future research on intelligent algorithms for mean field optimization, particularly using reinforcement learning method to design strategies for models w.th unknow. parameters.

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