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Acta Mechanica Sinica 2016年第4期32卷 720-730页

作者： w.yuan L.Li D.G.Zhang J.Z.Hong School of Science Nanjing University of Science and Technology Department of Engineering Mechanics Shanghai Jiao Tong University

A flexible beam with large overall rotating motion impacting with a rigid slope is studied in this paper. The tangential friction force caused by the oblique impact is analyzed. The tangential motion of the system is divided into a stick state and a slip state. The contact constraint model and Coulomb friction model are used respectively to deal with the two states. Based on this hybrid modeling method, dynamic equations of the system, which include all states（before, during, and after the collision）are obtained. Simulation results of a concrete example are compared with the results obtained from two other models： a nontangential friction model and a modified Coulomb model. Differences in the results from the three models are discussed. The tangential friction force cannot be ignored when an oblique impact occurs. In addition, the results obtained from the model proposed in this paper are more consistent with real movement.

关键词： collision oblique friction stick tangential considering Coulomb constraint coordinate rotating

China’s participation in the international RRT for I_(c) measurement of superconducting cables organized by IEC/TC90

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Superconductivity 2022年第1期1卷 27-33页

作者： J.Li Y.Shi G.M.Zhang L.w.Jing J.X.Zheng C.L.Liu w.yuan Y.S.wang M.Song Y.J.Xia X.H.Zong Y.w.Han D.N.Zheng X.J.Zhou T.Matsushita G.Nishijima The Institute of Physics Chinese Academy of SciencesBeijing 100190China The Institute of Electrical Engineering Chinese Academy of SciencesBeijing 100190China The Institute of Plasma Physics Chinese Academy of SciencesHefei 230031China Eastern Superconductor Science&Technology(Suzhou)Co LtdSuzhou 215299China Guangdong Power Grid Corporation Guangzhou 510630China Shanghai International Superconductor Technology Co LtdShanghai 200444China Department of Computer Science and Electronics Kyushu Institute of Technology Iizuk1Japan National Institute for Materials Scienc5 Tsukuba 305-0003Japan

Currently,IEC/TC90 is working on standardizing the method for measuring critical current(Ic)in superconducting *** the end of 2020,an international round robin test(RRT)was organized,in which five Chinese institutions participated,and four accomplished the *** electric-field versus current(E-I)curves obtained by each institution are highly *** obtained by different institutions are nearly identical after appropriate curve averaging,indicating high reproducibility,except the last participant's inner core *** discrepancy was later determined to be the result of sample cable *** excluding highly deviated data,it is determined that the maximum relative standard uncertainty in I_(c) is 0.7%,and the maximum relative standard uncertainty in n-value is 12.8%.The I_(c)values are comparable to Japan's domestic RRT results,but the n-values are significantly *** test results support the DC four-terminal method as a recommended test method,with a target relative uncertainty of less than 2%for the Ic value.

关键词： Superconducting cable Round robin test Standardization

Investigation of a mesospheric bore event over Northern China

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Investigation of a mesospheric bore event over Northern Chin...

锑剂对于循环系的药理 6.酒石酸锑钠对于一些循环反射的作用分析(简报)

中国空间科学学会空间物理学专业委员会第十五届全国日地空间物理学研讨会

作者： Q.Li J.Xu J.Yue X.Liu w.yuan B.Ning S.Guan J.P.Younger State Key Laboratory of Space weather Center for Space Science and Applied ResearchChinese Academy of Sciences Graduate University of the Chinese Academy of Sciences Hampton University HamptonVAUSA College of Mathematics and Information Science Henan Normal University Beijing National Observatory of Space Environment Institute of Geology and GeophysicsChinese Academy of Sciences School of Chemistry and Physics University of AdelaideAdelaideSouth AustraliaAustralia

A mesospheric bore event was observed using an OH all-sky airglow imager(ASAI)at Xinglong(40.2oN,117.4oE),in northern China,on the night of 08-09 January *** observations by a Doppler meteor radar,a broadband sodium lidar,and TIMED/SABER OH intensity and temperature measurements are used to investigate the characteristics and environment of the bore propagation and the possible relations with the Na density *** bore propagated from northeast to southwest and divided the sky into bright and dark *** calculations show that the bore has an average phase velocity of 68 m/*** crests following the bore have a horizontal wavelength of2 *** parameters are consistent with the hydraulic jump theory proposed by Dewan and Picard,as well as the previous bore *** wind measurements from the Doppler meteor radar at Shisanling(40.3oN,116.2oE)and temperature data from SABER on board the TIMED satellite are used to characterize the propagating environment of the *** result shows that a Thermal-Doppler duct exists near the OH layer that supports the horizontal propagation of the *** Na lidar observations at Yanqing(40.4°N,116.0°E)suggest that there is a downward displacement of Na density during the passage of the mesospheric bore event.

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上海第一医学院学报 1957年第1期 9-15页

作者：梁兆年袁玮张昌绍上海第一医学院药理学上海第一医学院药理学教研组上海第一医学院药理学教研组进修员西北畜牧兽医学院

于麻醉犬猫进行实验,发现酒石酸锑钠12mg/Kg 静脉注射能显著减弱下列数种循环反射:夹颈动脉与脾臓血管内注入烟碱所致的升压反射,电刺激迷走神神向中段所致的升压反射与降压反射。进一步分析证明,锑剂并不影响植物神经介质乙醯胆碱与肾... 详细信息

于麻醉犬猫进行实验,发现酒石酸锑钠12mg/Kg 静脉注射能显著减弱下列数种循环反射:夹颈动脉与脾臓血管内注入烟碱所致的升压反射,电刺激迷走神神向中段所致的升压反射与降压反射。进一步分析证明,锑剂并不影响植物神经介质乙醯胆碱与肾上腺素的有关作用,也不影响迷走神经节与交感神经节以及它们节后纤维末梢的传导。因此,锑剂在以上循环反射的反射弧中,最大可能即作用于其中枢环节,即有关的皮质下中枢,此外对于肾上腺髓质的抑制作用亦有重要的意义。

关键词：锑剂反射弧循环系酒石酸锑钾吐酒石祛痰药肾上腺素肾上腺能α-受体兴奋药电刺激麻醉犬受器静脉注射对于

Insight Into the Separation-of-Variable Methods for the Closed-Form Solutions of Free Vibration of Rectangular Thin Plates

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 329-355页

作者： Yufeng Xing Ye yuan Gen Li Institute of Solid Mechanics Beihang University(BUAA)Beijing100191China

The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical *** taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue ***,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are *** is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well.

关键词： Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method

锑剂对于循环系的药理 5.酒石酸锑钠对于化学感受器的作用

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上海第一医学院学报 1957年第1期 7-9页

作者：袁玮王义明杨藻宸张昌绍上海第一医学院药理学教研组上海第一医学院药理学教研组进修员沈阳医学院药理教研组

洒石酸銻鉀治疗中偶发的突然死亡,多数学者认为由于心室顫动所致。根据无锡血吸虫病防治所对于50死亡病例的分析,有半数病例在发生第一次阵攣抽搐前曾受到外界的刺激,这些刺激包括了一些普通的动作如唱歌、起床大小便或情绪激动等,足以... 详细信息

洒石酸銻鉀治疗中偶发的突然死亡,多数学者认为由于心室顫动所致。根据无锡血吸虫病防治所对于50死亡病例的分析,有半数病例在发生第一次阵攣抽搐前曾受到外界的刺激,这些刺激包括了一些普通的动作如唱歌、起床大小便或情绪激动等,足以指明在这种反应中,除锑剂对于心肌的直接作用外,可能有某种神经反射机制的

关键词：受器反射性锑剂酒石酸羟基羧酸药理对于

The dopaminergic system and Alzheimer's disease

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Neural Regeneration Research 2025年第9期20卷 2495-2512页

作者： Yuhan Zhang yuan Liang Yixue Gu International Medical College Chongqing Medical UniversityChongqingChina College of Pharmacy Chongqing Medical UniversityChongqingChina Department of Neurology The First Affiliated Hospital of Chongqing Medical UniversityChongqing Key Laboratory of NeurologyChongqingChina

Alzheimer's disease is a common neurodegenerative disorder in older *** its prevalence,its pathogenesis remains unclea *** addition to the most widely accepted causes,which in clude excessive amyloid-beta aggregation,tau hyperphosphorylation,and deficiency of the neurotransmitter acetylcholine,numerous studies have shown that the dopaminergic system is also closely associated with the occurrence and development of this *** is a crucial catecholaminergic neurotransmitter in the human ***-associated treatments,such as drugs that target dopamine receptor D and dopamine analogs,can improve cognitive function and alleviate psychiatric symptoms as well as ameliorate other clinical *** r,therapeutics targeting the dopaminergic system are associated with various adverse reactions,such as addiction and exacerbation of cognitive *** review summarizes the role of the dopaminergic system in the pathology of Alzheimer's disease,focusing on currently available dopamine-based therapies for this disorder and the common side effects associated with dopamine-related *** aim of this review is to provide insights into the potential connections between the dopaminergic system and Alzheimer's disease,thus helping to clarify the mechanisms underlying the condition and exploring more effective therapeutic options.

关键词： adverse drug reaction Alzheimer's disease catecholamine dopamine receptor dopamine receptor heterodimers dopaminergic system neurodegenerative disease neurotransmitter signaling pathways traditional Chinese medicine treatment

Computed tomography enterography-based radiomics for assessing mucosal healing in patients with small bowel Crohn's disease

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world Journal of Gastroenterology 2025年第3期31卷 62-72页

作者： Hao Ding yuan-yuan Fang wen-Jie Fan Chen-Yu Zhang Shao-Fei wang Jing Hu wei Han Qiao Mei Department of Gastroenterology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Radiation Oncology The First Affiliated Hospital of Anhui Medical UniversityHefei 230022Anhui ProvinceChina Department of Gastroenterology Suzhou First People's HospitalSuzhou 234099Anhui ProvinceChina

BACKGROUND Mucosal healing(MH)is the major therapeutic target for Crohn's disease(CD).As the most commonly involved intestinal segment,small bowel(SB)assessment is crucial for CD ***,it poses a significant challenge due to its limited accessibility through conventional endoscopic *** To establish a noninvasive radiomic model based on computed tomography enterography(CTE)for MH assessment in SBCD *** Seventy-three patients diagnosed with SBCD were included and divided into a training cohort(n=55)and a test cohort(n=18).Radiomic features were obtained from CTE images to establish a radiomic *** demographics were analysed to establish a clinical model.A radiomic-clinical nomogram was constructed by combining significant clinical and radiomic *** diagnostic efficacy and clinical benefit were evaluated via receiver operating characteristic(ROC)curve analysis and decision curve analysis(DCA),*** Of the 73 patients enrolled,25 patients achieved *** radiomic-clinical nomogram had an area under the ROC curve of 0.961(95%confidence interval:0.886-1.000)in the training cohort and 0.958(0.877-1.000)in the test cohort and provided superior clinical benefit to either the clinical or radiomic models alone,as demonstrated by *** These results indicate that the CTE-based radiomic-clinical nomogram is a promising imaging biomarker for MH and serves as a potential noninvasive alternative to enteroscopy for MH assessment in SBCD patients.

关键词： Crohn’s disease Computed tomography enterography Mucosal healing Nomogram Radiomics

Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder

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Neural Regeneration Research 2025年第6期20卷 1541-1554页

作者： Jinmei Ye Cong Duan Jiaxin Han Jinrong Chen Ning Sun yuan Li Tifei yuan Daihui Peng Division of Mood Disorder Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina

In the pathogenesis of major depressive disorder, chronic stress-related neuroinflammation hinders favorable prognosis and antidepressant response. Mitochondrial DNA may be an inflammatory trigger, after its release from stress-induced dysfunctional central nervous system mitochondria into peripheral circulation. This evidence supports the potential use of peripheral mitochondrial DNA as a neuroinflammatory biomarker for the diagnosis and treatment of major depressive disorder. Herein, we critically review the neuroinflammation theory in major depressive disorder, providing compelling evidence that mitochondrial DNA release acts as a critical biological substrate, and that it constitutes the neuroinflammatory disease pathway. After its release, mitochondrial DNA can be carried in the exosomes and transported to extracellular spaces in the central nervous system and peripheral circulation. Detectable exosomes render encaged mitochondrial DNA relatively stable. This mitochondrial DNA in peripheral circulation can thus be directly detected in clinical practice. These characteristics illustrate the potential for mitochondrial DNA to serve as an innovative clinical biomarker and molecular treatment target for major depressive disorder. This review also highlights the future potential value of clinical applications combining mitochondrial DNA with a panel of other biomarkers, to improve diagnostic precision in major depressive disorder.

关键词： biomarker cytokine exosomes inflammasome major depressive disorder microglia mitochondrial DNA mitochondrial dysfunction neuroinflammation Toll-like receptor

Sex differences in aging and injured brain

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Neural Regeneration Research 2025年第10期20卷 2901-2902页

作者： Jordan N.williamson yuan Yang University of Illinois Urbana-Champaign Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Carle Foundation Hospital Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA University of Illinois Urbana-Champaign Beckman Institute for Advanced Science and TechnologyUrbanaILUSA Northwestern University Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Background:The prevalence,age of onset,and symptomatology of traumatic brain injury,stroke,and neurodegenerative diseases(such as Alzheimer’s disease(AD),Parkinson’s disease,amyotrophic lateral sclerosis,and Huntington’s disease)differ substantially between males and *** higher prevalence of these brain disorders has been attributed to females having a greater longevity compared with *** one of the greatest risk factors of acquired brain injury(such as stroke,traumatic brain injury caused by fall)and neurodegenerative disease is age.

关键词： Huntington prevalence traumatic