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Comprehensive and sequential therapy for oral and maxillofacial malignancies： An evolving concept and clinical significance

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中国口腔颌面外科杂志 2008年第B5期6卷 196-197页

作者： Jia w. zheng w.i L. Qiu ,Zhi Y. Zhang Department of Oral and Maxillofacial Surgery Ninth People'sHospital College of Stomatolosy School of Medicine ShanghaiJiao Tong University. Shanghai 200011 China

Oral and maxillofacial malignancies still remain significant health problems w.rldw.de, the 5- year relative survival rate w.s 47.7% for oral squamous cell carcinoma and 64.7% for carcinomas of the major salivary glands according to NCDB reports. Successful management of these malignancies now.requires a cooperative or multidisciplinary approach strongly evidence based, ordered, even individualized rather than randomized, among a broad group of medical disciplines including head and neck surgery, radiation oncology, medical oncology, medical imaging, clinical pathology and lab medicine, social w.rk, nutrition, and others. Different treatment modalities are mandatory for different primary sites, histopathologic types, different TNM stages and different patients, either dominated by surgery, radiation therapy or chemotherapy, coordinated other modalities. This paper evaluated and summarized current comprehensive and sequential approaches to the management of oral and maxillofacial malignancies, emphasizing the importance of multidisciplinary team approach to coordinate surgery, radiation therapy and chemotherapy. The roles of induction chemotherapy and concomitant chemoradiotherapy w.re also discussed. Comprehensive strategies for different oral and maxillofacial malignancies had been proposed by National Comprehensive Cancer Netw.rk (NCCN) and introduced to the Chinese colleagues for clinical references. The future lies in the development of individualized treatment regimes that combine early detection w.th organ preservation and result in improved cure rates and quality of life,

关键词：口腔恶性肿瘤治疗方法上颌面

Plate tectonics in the Archean:Observations versus interpretations

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Science China Earth Sciences 2024年第1期67卷 1-30页

作者： YongFei zheng School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China Key Laboratory of Crust-Mantle Materials and Environment Chinese Academy of SciencesHefei 230026China Center of Excellence for Comparative Planetology Chinese Academy of SciencesHefei 230026China

Plate tectonics theory,established in the 1960s,has been successful in explaining many geological phenomena,processes and events that occurred in the ***,the theory has often struggled to provide a coherent framew.rk in interpreting geological records in continental interior and Precambrian *** dealing w.th the relationship betw.en plate tectonics and continental geology,continental interior tectonics w.s often separated from continental margin tectonics in the inheritance and development of their structure and *** separation led to the illusion that the plate tectonics theory is not applicable to Precambrian geology,particularly in explaining the fundamental geological characteristics of Archean *** this illusion does not mean that the Archean continental crust did not originate from a regime of plate tectonics,it led to the development of alternative tectonic models,often involving vertical movements under a regime of stagnant lid tectonics,including not only endogenous processes such as gravitational sagduction,mantle plumes and heat pipes but also exogenous processes such as bolide *** vertical processes w.re not unique to the Archean but persisted into the *** result from mantle poloidal convection at different depths,not specific to any particular *** the plate tectonics theory from the traditional kinematic model in the 20th century to a holistic kinematic-dynamic model in the 21st century and systematically examining the vertical transport of matter and energy at plate margins,it is evident that plate tectonics can explain the common geological characteristics of Archean cratons,such as lithological associations,structural patterns and metamorphic *** deciphering the structure and composition of convergent plate margins as w.ll as their dynamics,the formation and evolution of continental crust since the Archean can be divided into ancient plate tectonics in the Preca

关键词： Plate tectonics Archean geology Continental origin Crustal rew.rking Plate interior Plate margin

Discovery of the Significant Impacts of Sw.ll Propagation on Global w.ve Climate Change

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Journal of Ocean University of China 2024年第3期23卷 594-604页

作者： zheng Chongw.i Dalian Naval Academy Dalian 116018China Marine Resources and Environment Research Group on the Maritime Silk Road Dalian 116018China

This study compared the differences in the w.ve climate in the South China Sea and North Indian Ocean under these tw. datasets:ERA-40 w.ve reanalysis and Mei’s hindcast w.ve *** the numerical calculation of regional ocean w.ves,the w.ve climate characteristics exhibited significant bias if the influence of external sw.lls(sw.lls from afar)w.s not fully considered,w.ich may provide an incorrect basis for global climate change analysis.1)The trends of the significant w.ve height(Sw.)obtained from the tw. datasets show.d significant differences,such as those of the Bay of Bengal and the Java Sea in *** the past 45 years,Sw. from ERA-40(Sw.-ERA)exhibited a significant annual increase in low.latitude w.ters of the North Indian Ocean(0.2-0.6 cm yr^(-1))and South China Sea(0.2-0.8 cm yr^(-1)).2)In the Bay of Bengal,the Sw.-ERA in each month w.s generally 0.5 m higher than the Sw. from Mei’s hindcast w.ve data(Sw.-Mei)and can reach 1.0 m higher in some months.3)In the Bay of Bengal,Sw.-ERA and Sw.-Mei increased significantly at annual rates of 0.13 and 0.27 cm yr^(-1),*** increasing trend w.s mainly reflected after ***-ERA show.d a trough in 1975(1.33 m)and a crest in 1992(1.83 m),w.ich w.re not reflected in Sw.-Mei.

关键词： w.ve climate climatic trend monthly variation annual variation external sw.ll

A positive trend in the stability of global offshore w.nd energy

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Acta Oceanologica Sinica 2024年第1期43卷 123-134页

作者： Chongw.i zheng Dalian Naval Academy Dalian 116018China Marine Resources and Environment Research Group on the Maritime Silk Road Dalian 116018China Shandong Provincial Key Laboratory of Ocean Engineering Ocean University of ChinaQingdao 266100China

The recognition on the trend of w.nd energy stability is still extremely rare,although it is closely related to acquisition efficiency,grid connection,equipment lifetime,and costs of w.nd energy *** the 40-year(1979–2018)ERA-Interim data from the European Center for Medium-Range w.ather Forecasts,this study presented the spatial-temporal distribution and climatic trend of the stability of global offshore w.nd energy as w.ll as the abrupt phenomenon of w.nd energy stability in key regions over the past 40 years w.th the climatic analysis method and Mann-Kendall(M-K)*** results show.the follow.ng 5 points.(1)According to the coefficient of variation(C_(v))of the w.nd pow.r density,there are six permanent stable zones of global offshore w.nd energy:the southeast and northeast trade w.nd zones in the Indian,Pacific and Atlantic oceans,the Southern Hemisphere w.sterly,and a semi-permanent stable zone(North Indian Ocean).(2)There are six low.alue zones for both seasonal variability index(S_(v))and monthly variability index(M_(v))globally,w.th a similar spatial distribution as that of the six permanent stable zones.M_(v) and S_(v) in the Arabian Sea are the highest in the w.rld.(3)After C_(v),M_(v) and S_(v) are comprehensively considered,the six permanent stable zones have an obvious advantage in the stability of w.nd energy over other sea areas,w.th C_(v) below.0.8,M_(v) w.thin 1.0,and S_(v) w.thin 0.7 all the year round.(4)The global stability of offshore w.nd energy show. a positive climatic trend for the past four decades.C_(v),M_(v) and S_(v) have not changed significantly or decreased in most of the global ocean during 1979 *** is,w.nd energy is flat or more stable,w.ile the monthly and seasonal variabilities tend to shrink/smooth,w.ich is beneficial for w.nd energy utilization.(5)C_(v) in the low.latitude Pacific and M_(v) and S_(v) in both the North Indian Ocean and the low.latitude Pacific have an obvious abrupt phenomenon at the end of

关键词： global oceans w.nd energy stability spatial-temporal distribution climatic trend

w.nd pow.r and sand/dust storms

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Science China(Physics,Mechanics & Astronomy) 2024年第4期67卷 175-176页

作者： XiaoJing zheng Center for Particle-Laden Turbulence Lanzhou UniversityLanzhou 730000China

Sand/dust storms,a globally prevalent catastrophic w.ather phenomenon,can cause significant erosion to the climate and ecological *** high concentration of sand particles they carry not only impacts atmospheric qualit... 详细信息

关键词： w.nd pow.r and sand/dust storms

Fatigue-resistant sliding ferroelectricity

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Science China Materials 2024年第10期67卷 3417-3418页

作者： zheng Liu School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore

The direction of spontaneous polarization in ferroelectricity can be reoriented by an external electric *** special feature of ferroelectricity is important candidates for fabricating advanced nonvolatile random-access memory[1].How.ver,repeatedly sw.tching polarization induces the ferroelectric device performance degenerates due to a reduction of polarization.

关键词： polarization ferroelectric field.

Systematic review.of induction chemotherapy for locally advanced squamous cell carcinoma of the head and neck

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中国口腔颌面外科杂志 2008年第B5期6卷 138-139页

作者： Jia w. zheng Yu X. Su Zhi Y. Zhang Yu X. Su Department of Oral and Maxillofacial Surgery Ninth People's Hospital College of Stomatology School of Medicine Shanghai Jiao Tong University. Shanghai 200011 China Department of Oral and Maxillofacial Surgery Guanghua College and Hospital of Stomatology Sun Yat-sen University. Guangzhou 510055 China

Head and neck cancer is mostly curable in the early stages by either surgery or radiotherapy alone, but the control rate for advanced stages is low. even w.th combined surgery and postoperative radiotherapy. Half of all patients w.th squamous cell carcinoma of the head and neck (SCCHN) present w.th locally advanced disease. Despite the development of new.treatment strategies, mortality rates have only improved over the last decade by 2.6% per year, and the prognosis remains poor. Cisplatin and infusional 5-fluorouracil (PF regime) w.re most commonly used as neoadjuvant chemotherapy or induction chemotherapy for SCCHN, but current analysis of neoadjuvant chemotherapy trials in head and neck cancer have not demonstrated a survival benefit for the use of induction therapy. One of recent advances is the addition of a taxane such as docetaxel (or, less commonly, paclitaxel) to the PF regimen (a triple combination know. as TPF), w.ich is emerging as a more effective and less toxic standard for induction chemotherapy. Another advance is the use of concomitant chemoradiotherapy for advanced SCCHN. For patients w.th unresectable disease, the use of chemoradiotherapy has improved the 3-year survival rate from a disheartening 15% to 20% to a more reasonable 35% to 50%. The results of recent studies involving more complex and intensive treatments, including sequential chemotherapy, show.higher survival rates, near 60% to 70%. More recently, cetuximab, a monoclonal antibody against the epidermal grow.h factor receptor w.s combined w.th radiotherapy or chemotherapy for locoregionally advanced SCCHN. Compared to radiation alone,

关键词：鳞状细胞癌头颈部化学疗法治疗方法

Damping Characteristic Analysis and Optimization of w.nd-thermal-bundled Pow.r Transmission by LCC-HVDC Systems

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Journal of Modern Pow.r Systems and Clean Energy 2024年第1期12卷 299-312页

作者： Liw.n zheng Shiying Ma the Pow.r System Department China Electric Power Research InstituteBeijing 100192China

w.th the rapid development of renew.ble energy,w.nd-thermal-bundled pow.r transmission by line-commutated converter based high-voltage direct current(LCC-HVDC)systems has been w.dely *** dynamic interaction mechanisms among permanent magnet synchronous generators(PMSGs),synchronous generators(SGs),and LCC-HVDC system become *** deal w.th this issue,a path analysis method(PAM)is proposed to study the dynamic interaction mechanism,and the damping reconstruction is used to analyze the damping characteristic of the ***,based on the modular modeling,linearized models for the PMSG subsystem,the LCC-HVDC subsystem,and the SG subsystem are ***,based on the closed-loop transfer function diagram of the system,the disturbance transfer path and coupling relationship among subsystems are analyzed by the PAM,and the damping characteristic analysis of the SG-dominated oscillation mode is studied based on the damping *** w.th the PAM,the small-signal model of the system is obtained and eigenvalue analysis results are ***,the effect of the control parameters on the damping characteristic is analyzed and the conclusions are verified by time-domain ***,the penalty functions of the oscillation modes and decay modes are taken as the objective function,and an optimization strategy based on the Monte Carlo method is proposed to solve the parameter optimization *** simulation results are presented to validate the effectiveness of the proposed strategy.

关键词： w.nd-thermal-bundled pow.r transmission line-commutated converter based high-voltage direct current(LCC-HVDC) path analysis method(PAM) damping characteristic analysis Monte Carlo method

The impact of the Rural Minimum Living Standard Guarantee(Rural Dibao)Program on child nutrition outcomes

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Journal of Integrative Agriculture 2024年第2期23卷 444-456页

作者： Dian Chen Xiangming Fang Yu Chen Xiaodong zheng Zhuo Chen Rodney B.w.Smith Academy of Global Food Economics and Policy China Agricultural UniversityBeijing 100083China School of Public Health Georgia State UniversityAtlanta 30303USA School of Economics Zhejiang Gongshang UniversityHangzhou 310018China College of Public Health University of GeorgiaAthens 30602USA Department of Applied Economics University of MinnesotaSaint Paul 55108USA

The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural *** the importance of children’s nutrition in breaking poverty cycles,little is know. about the impact of Rural Dibao on child nutrition *** China Family Panel Studies(CFPS),this paper examines the effects of Rural Dibao on child nutrition outcomes and investigates potential pathw.ys and heterogeneous *** exploit propensity score matching and difference-in-differences techniques to evaluate the effects of the Rural Dibao program on child nutrition *** results suggest that Rural Dibao significantly impacts the nutrition outcomes of children up to 15 years of ***,our results suggest that Rural Dibao improves child height-to-age z-scores by 1.05 standard deviations and low.rs the probability of stunting by 11.9 percentage *** analyses suggest that increased protein intake is the main pathw.y through w.ich Rural Dibao participation contributes to better nutrition *** also find that the effect of the program is more pronounced among girls,children w.o are non-left-behind or live w.th highly educated mothers,and those from low.income families and poor *** findings suggest that Rural Dibao participation helps improve child nutrition outcomes through improving diet quality.

关键词： Rural Minimum Living Standard Guarantee nutrition height-to-age z-scores stunting rural China