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Morbidity and Mortality of Acute Renal Failure in COVID-19 Patients in Intensive Care According to Waves/Variant: Case of the Grand Hôpital de l’Est Francilien Site de Meaux

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Open Journal of Internal Medicine 2024年第1期14卷 16-29页

作者： Khazy Anga Ariel Makembi Éric Amisi Éric Delpierre Vivien Hong Tuan ha Wilfrid Mbombo Jean Claude Mubenga Dan Kankonde Chris Nsituavibidila Lionel Diyamona Noelly Mukuna Gracia Likinda Tharcisse Mabiala Martin Mukenga Médard Bula-Bula Berthe Barhayiga Département d’Anesthésie Réanimation Université de Kinshasa Kinshasa République démocratique du Congo Service de Réanimation Grand H&ocircpital de l’Est Francilien Meaux France Département de Médecine Interne Université de Kinshasa Kinshasa République démocratique du Congo Service d’Anesthésie Réanimation Centre Hospitalier Monkole Kinshasa République démocratique du Congo Department of Anaesthesia and Intensive Care H&ocircpital Général de Référence de Kinshasa Kinshasa République démocratique du Congo Department of Anaesthesia and Intensive Care Université Protestante du Congo Kinshasa République démocratique du Congo

Introduction: The incidence of acute renal failure (ARF) varies between 20% and 40% of cases for COVID-19 patients admitted to the intensive care unit, with very high mortality, but heterogeneous according to the different epidemic waves, probably due to the genetic variant phenomenon of the virus. The aim of this study is to determine the morbidity and mortality of COVID-19 patients admitted with ARF to the intensive care unit of the Grand H?pital Est Francilien (GHEF) according to the waves and variants. Methods: Cross-sectional observational study of COVID-19 patients with ARF admitted to the intensive care unit of the GHEF site in Meaux covering the period from March 1st 2020 to December, 31st 2021. Per-hospitalisation and outcome data were collected and analysed with SPSS version 25.0 software using the Chi-square or Fischer’s exact test or Student’s t-test and logistic regression for p Results: A total of 86 patients were included. The mean age was higher (70 ± 8.5) in patients in the fourth wave than in the other waves (p = 0.015), with male predominance in all waves without significant difference. Co-morbidities: hypertension, diabetes, heart disease, dyslipidaemia and arrhythmia complete with fibrillation were present in all waves. The majority of patients were classified as KDIGO 1 for the different waves (1st: 61.9%, 2nd: 86.5%, 3rd: 80%, and 4th: 75%), with the same trend according to variant (alpha: 80%, beta: 75%, delta: 81.3%, omicron: 75%). Mortality by the wave was: 1st: 28.5%, 2nd: 37.5%, 3rd: 23% and 4th: 11%) and by variant: alpha: 24.2%, beta: 44.8%, delta: 20.7%, omicron: 10.3%). Overall mortality was 33.7%. Case fatality was higher in the fourth wave. Hypertension, shock, failure to recover renal function, acute lung oedema, ventilator-associated lung disease and hyperkalaemia were factors associated with mortality (p Conclusion: Acute renal failure is common in COVID-19 patients admitted to the intensive care unit, and m

关键词： Mortality COVID-19 Morbidity Renal Failure Intensive Care Unit

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Significance of age and comorbidity as prognostic indicators for patients with bladder cancer

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Asian Journal of Andrology 2010年第5期12卷 766-774页

作者： Moon Soo ha In Ho Chang Department of Urology College of Medicine Chung-Ang University Seou1140-75 7 Korea

The aim of this study was to determine the impact that age and comorbidity status have on both overall and bladder cancer-specific survival of bladder cancer patients. We obtained medical information pertaining to a population of 528 patients with newly diagnosed bladder cancer from Chung-Ang University Hospital cancer registry. The Adult Comorbidity Evaluation-27 （ACE-27） test, which has been previously validated in adult cancer patients, was used to assess comorbidity. We evaluated differences in the demographic and clinical characteristics of included patients, as well as differences in the treatments they received after categorizing them by age. The median age at the time of bladder cancer diagnosis of the entire cohort was 63 years, and the median follow-up time was 97 months. Of the 528 patients who were included in our study, 303 had at least one comorbid condition and 249 died during the follow-up period. When patients were stratified by age, we found that older patients had a higher proportion of severe comorbidities （P 〈 0.01） than younger patients, and that a lower proportion of them underwent radical cystec- tomy for invasive bladder cancer （IBC）（P 〈 0.01）. By multivariate analysis, we found that older age was predictive of lower overall survival （OS） and bladder cancer-specific survival （BCSS） rates among patients with superficial bladder cancer （SBC） and of lower OS rates among patients with IBC. We also found that moderate-severe comorbidity status and treatment through a bladder-conserving approach were predictive of lower OS and cancer-specific survival rates among patients with IBC. The disparity between overall deaths and bladder cancer deaths was shown in SBC and increased along with age and higher comorbidity. Age and comorbidity were found to be independent predictive factors of OS and BCSS among bladder cancer patients, and explained the disparity that we observed between overall bladder cancer-specific mortality rates.

关键词： age comorbidity neoplasm prognostic indicator urinary bladder

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Bifurcation Analysis of the Voltage Controlled Photosensitive Chaotic Oscillator

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Chinese Physics Letters 2013年第6期30卷 42-45页

作者： Van ha Nguyen han Jung Song Department of Nano Systems Engineering Inje UniversityGimhae 621-749Korea Center for Nano Manufacturing Inje UniversityGimhae 621-749Korea

A photosensitive chaotic oscillator which can be controlled with light illumination under various control voltage levels is *** oscillator consists of a photodiode for the light input,clock switches and capacitors for the sample and hold function,a nonlinear function that creates an adjustable chaos map,and a voltage shifter that adjusts the output voltage for *** optimizing the photodiode sub-circuit by using an available photodiode model in PC-based simulation program with integrated circuit emphasis to obtain a suitable output,the full chaotic circuit is verified with standard 0.6-μm complementary metal oxide semiconductor *** dynamics are analyzed as a function of the light intensity under different control voltage *** time series,frequency spectra,transitions in state spaces,bifurcation diagrams and the largest Lyapunov exponent are improved.

关键词： oscillator chaotic function

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市场营销一流本科专业育人特色打造实践与反思--以湖南工业大学商学院为例

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江苏商论 2024年第9期 22-25,41页

作者：杨金海彭穗湖南工业大学科技学院湖南株洲412008 湖南工业大学经济与管理学院湖南株洲412007

建设一流本科专业,事关实现内涵式发展全局。本文以湖南工业大学商学院为例,首先介绍了该院在市场营销一流专业建设中形成的育人工作特色,包括“‘三双’人才培养模式构建”“教师‘专业+行业背景’一体化能力提升”“学生三大核心能力... 详细信息

建设一流本科专业,事关实现内涵式发展全局。本文以湖南工业大学商学院为例,首先介绍了该院在市场营销一流专业建设中形成的育人工作特色,包括“‘三双’人才培养模式构建”“教师‘专业+行业背景’一体化能力提升”“学生三大核心能力培育”“教学方法与手段创新”“人才立体成长平台搭建”等五个方面。然后,总结归纳该院在市场营销一流本科专业建设中存在的主要问题;最后,在借鉴湖南省同类高校建设一流本科专业经验的基础上提出了对策建议。

关键词：市场营销一流本科专业内涵式发展

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企业ESG与资本市场表现——来自股票流动性的证据

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科学决策 2024年第4期 42-60页

作者：徐晟哈斯木其尔梁富友沈熙峰中南财经政法大学中国医药健康产业股份有限公司

在经济社会发展绿色化、低碳化态势下,ESG理念在资本市场中的地位日益凸显。文章基于2015—2021年我国A股上市公司数据,研究ESG表现对企业股票流动性的影响。研究发现,ESG表现显著提升了企业股票流动性,该效应在国有企业、大规模企业以... 详细信息

在经济社会发展绿色化、低碳化态势下,ESG理念在资本市场中的地位日益凸显。文章基于2015—2021年我国A股上市公司数据,研究ESG表现对企业股票流动性的影响。研究发现,ESG表现显著提升了企业股票流动性,该效应在国有企业、大规模企业以及市场化程度较高的地区企业中更显著。机制分析表明,企业ESG有利于提升投资者情绪和信息透明度,进而促进股票流动性。进一步研究发现,企业良好ESG表现所带来的股票流动性显著提升了企业价值和企业创新。发掘企业ESG在金融市场的作用效果,为活跃资本市场提供新的经验证据。

关键词： ESG 股票流动性投资者情绪信息透明度文本分析

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Effect of Length Scale Tuning of Background Error in WRF-3DVAR System on Assimilation of High-Resolution Surface Data for Heavy Rainfall Simulation

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Advances in Atmospheric Sciences 2012年第6期29卷 1142-1158页

作者： Ji-Hyun ha Dong-Kyou LEE Atmospheric Sciences Program School of Earth and Environmental SciencesSeoul National UniversitySeoul 151-747Korea

We investigated the impact of tuning the length scale of the background error covariance in the Weather Research and Forecasting （WRF） three-dimensional variational assimilation （3DVAR） system. In particular, we studied the effect of this parameter on the assimilation of high-resolution surface data for heavy rainfall forecasts associated with mesoscale convective systems over the Korean Peninsula. In the assimilation of high-resolution surface data, the National Meteorological Center method tended to exaggerate the length scale that determined the shape and extent to which observed information spreads out. In this study, we used the difference between observation and background data to tune the length scale in the assimilation of high-resolution surface data. The resulting assimilation clearly showed that the analysis with the tuned length scale was able to reproduce the small-scale features of the ideal field effectively. We also investigated the effect of a double-iteration method with two different length scales, representing large and small-length scales in the WRF-3DVAR. This method reflected the large and small-scale features of observed information in the model fields. The quantitative accuracy of the precipitation forecast using this double iteration with two different length scales for heavy rainfall was high; results were in good agreement with observations in terms of the maximum rainfall amount and equitable threat scores. The improved forecast in the experiment resulted from the development of well-identified mesoscale convective systems by intensified low-level winds and their consequent convergence near the rainfall area.

关键词： WRF 3DVAR tuning surface data heavy rainfall

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Tracking and Sensor Coverage of Spatio-temporal Quantities Using a Swarm of Artificial Foraging Agents

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Journal of Bionic Engineering 2016年第4期13卷 679-689页

作者： John Oluwagbemiga Oyekan Dongbing Gu Huosheng ha School of Aerospace Transport and Manufacturing Cranfield University College Road Cranfield MK43 OAL UK School of Computer Science and Electronic Engineering University of Essex Wivenhoe Park Colchester CO4 3SQ UK

Using a network of mobile sensors to track and map a dynamic spatio-temporal process in the environment is one of the current challenges in multi-agent systems. In this work, a distributed probabilistic multi-agent algorithm inspired by the bacte- rium foraging behavior is presented. The novelty of the algorithm lies in being capable of tracking and mapping a spa- tio-temporal quantity without the need of machine learning, estimation algorithms or future planning. This is unlike most current techniques that rely heavily on machine learning to estimate the distribution as well as the profile of spatio-temporal quantities. The experimental studies carried out in this work show that the algorithm works well by following the concentration gradient of a dynamic plume created under diffusive conditions. Furthermore, the algorithm is inherently capable of finding the source of a diffusive spatio-temporal quantity as well as performing environmental exploration. It is computationally tractable for simple agents, shown to adapt to its environment and can deal successfully with noise in sensor readings as well as in robot dynamics.

关键词： bioinspired algorithm artificial foraging swarm spatio-temporal mapping bacterium

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Performance of Forearm FMG for Estimating hand Gestures and Prosthetic hand Control

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Journal of Bionic Engineering 2019年第1期16卷 88-98页

作者： Nguon ha Gaminda Pankaja Withanachchi Yimesker Yihun Department of Mechanical Engineering Wichita State UniversityUSA Department of Electrical Engineering Wichita State UniversityUSA

This study is aimed at exploring the prediction of the various hand gestures based on Force Myography(FMG)signals generated through piezoelectric sensors banded around the *** the study,the muscles extension and contraction during specific movements were mapped,interpreted,and a control algorithm has been established to allow predefined grips and individual finger *** Tree Learning(DTL)and Support Vector Machine(SVM)have been used for classification and model *** of these estimated models generated an averaged accuracy of more than 80.0%,for predicting grasping,pinching,left flexion,and wrist *** the classification showed a distinct feature in the signal,a real-time control system based on the threshold value has been implemented in a prosthetic *** hand motion has also been recorded through Virtual Motion Glove(VMD)to establish dynamic relationship between the FMG data and the different hand *** classification of the hand gestures based on FMG signal will provide a useful foundation for future research in the interfacing and utilization of medical devices.

关键词： Force Myography(FMG) Surface Electromyography(sEMG) prosthetic hand gesture predictions and classifications bionic robot

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Endoscopic submucosal dissection for early gastric cancer:It is time to consider the quality of its outcomes

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World Journal of Gastroenterology 2023年第43期29卷 5800-5803页

作者： Gwang ha Kim Internal Medicine Pusan National University School of Medicine and Biomedical Research InstitutePusan National University HospitalBusan 47241South Korea

Endoscopic resection,particularly endoscopic submucosal dissection(ESD),is widely used as a standard treatment modality for early gastric cancer(EGC)when the risk of lymph node metastasis is *** with surgical gastrectomy,ESD is a minimally invasive procedure with additional advantages,such as preservation of the entire stomach and maintenance of the patient’s quality of ***,not all patients achieve curative resection after ESD of *** patients require surgical gastrectomy after ESD to achieve a curative *** surgery after ESD,owing to non-curative resection,places considerable emotional and financial burdens on ***,as the number of endoscopists performing ESD has increased,the rate of non-curative resection after ESD has increased *** order to decrease the non-curative resection rate,as well as determine the ideal rate of non-curative resection after ESD,it is time to consider quality indicators for the outcomes of ESD for EGC.

关键词： Early gastric cancer Endoscopic resection Quality indicator

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基于分布式存储的外包EHR隐私保护分类审计方案

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通信学报 2024年第9期45卷 26-39页

作者：张晓旭陈宇辰哈冠雄贾春福南开大学网络空间安全学院天津300350 天津市网络与数据安全技术重点实验室天津300350

随着电子医疗领域的发展,电子健康记录(EHR)常被外包到雾节点上进行分布式存储以提升可靠性。EHR中包含大量隐私信息,然而数据外包易造成安全隐患,可能破坏EHR的完整性与隐私性。为确保EHR的安全存储,提出一种高效的基于EHR分类的分布... 详细信息

随着电子医疗领域的发展,电子健康记录(EHR)常被外包到雾节点上进行分布式存储以提升可靠性。EHR中包含大量隐私信息,然而数据外包易造成安全隐患,可能破坏EHR的完整性与隐私性。为确保EHR的安全存储,提出一种高效的基于EHR分类的分布式数据完整性审计方案。该方案将分类标签与布隆过滤器相结合以提升审计效率,利用Shamir秘密共享完成分布式审计,采用属性基可搜索加密以保护EHR所属类别信息的隐私。实验结果表明,所提方案的通信开销和计算开销较低。

关键词：分布式存储数据审计 EHR Shamir秘密共享属性基可搜索加密

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