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An approach to net-centric control automation of technological processes within industrial IoT systems

Advances in Manufacturing 2017年第4期5卷 388-393页

作者： Nikita Voinov Igor Chernorutsky Pavel Drobintsev vsevolod kotlyarov Institute of Computer Science and Technology Peter the Great St. Petersburg Polytechnic UniversityPolytechnicheskaya 29 Saint Petersburg Russia 195251

The use of industrial internet networks with net- centric control is the driving trend behind the future material manufacturing of goods and services. The promising future of this approach is provided by these complex net-centric systems functioning with high relia- bility. The problem of intelligent net-centric control and reliable network functioning is fundamental, with the additional requirement that the system should preserve stakeholder security and privacy according to policies. The issue is that such systems are characterized by complex multi-parameter operability modes controlled by various criteria. This study considers an approach to providing reliable management of complicated Internet of things （IoT） systems. This is achieved by solving multi-criteria tasks over many processes of various physical natures. Corresponding methods of hierarchical decomposition of multi-criteria tasks, process levels of multi-criteria opti- mization, specifics of aggregation levels, and the master equation of the optimization process are described.

关键词： Net-centric control Technological process Internet of things (IoT) Reliability Multi-criteria optimization

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Importance of the gut microbiota in the gut-liver axis in normal and liver disease

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World Journal of Hepatology 2024年第6期16卷 878-882页

作者： Stanislav kotlyarov Department of Nursing Ryazan State Medical UniversityRyazan 390026Russia

The gut microbiota is of growing interest to clinicians and *** is because there is a growing understanding that the gut microbiota performs many different functions,including involvement in metabolic and immune processes that are systemic in *** liver,with its important role in detoxifying and metabolizing products from the gut,is at the forefront of interactions with the gut *** details of these interactions are not yet known to clinicians and researchers,but there is growing evidence that normal gut microbiota function is important for liver *** the same time,factors affecting the gut microbiota,including nutrition or medications,may also have an effect through the gut-liver axis.

关键词： Gut microbiota Liver Gut-liver axis Immunity Non-alcoholic fatty liver disease

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Immune and metabolic cross-links in the pathogenesis of comorbid non-alcoholic fatty liver disease

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World Journal of Gastroenterology 2023年第4期29卷 597-615页

作者： Stanislav kotlyarov Department of Nursing Ryazan State Medical UniversityRyazan 390026Russia

In recent years,there has been a steady growth of interest in non-alcoholic fatty liver disease(NAFLD),which is associated with negative epidemiological data on the prevalence of the disease and its clinical *** is closely related to the metabolic syndrome and these relationships are the subject of active research.A growing body of evidence shows cross-linkages between metabolic abnormalities and the innate immune system in the development and progression of *** links are bidirectional and largely still unclear,but a better understanding of them will improve the quality of diagnosis and management of *** addition,lipid metabolic disorders and the innate immune system link NAFLD with other diseases,such as atherosclerosis,which is of great clinical importance.

关键词： Non-alcoholic fatty liver disease Metabolism Lipid metabolism Lipid Fat Innate immune system Pathogenesis

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