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Computational Comparison of One Piece Metacarpo-Phalangeal/Phalangeal-Phalangeal Total Joint Replacements

作者： (泰)威拉昆·昂撒考(Weerakorn Ongsakul) (越)天·语·屋(dieu Ngoc vo)

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Journal of Biomedical Science and Engineering 2014年第7期7卷 427-433页

作者： Andrew C. Weems Ha Van vo Department of Biomedical Engineering Mercer University Macon USA

Trauma, osteoarthritis and rheumatoid arthritis can destroy the articulating cartilage in small and large joints, especially in the metacarpo [tarso] phalangeal (MCP/MTP) and phalangeal-phalangeal (PIP) joints. Single piece finger prosthetic designs can reduce pain and correct aesthetic issues, with problems on contemporary designs including decreased stability, lack of fixation and loss of functionality. The examined implants are representative models of currently available total joint replacement (TJR) designs for MCP replacement, such as the Swanson one piece implant. These implants have been shown clinically to have a high failure rate (up to 90%), but the cause of failure is unknown. Compressive studies using a 50 N force and medial-lateral loads of 50 N perpendicular to the longitudinal axis of the arms of the implant were individually applied. Due to material failings, lower values had to be used in some cases. Maximum stress values were found for flexion loading;the Swanson approximation had a peak stress of 8.71 GPa at the interface of the joint arm and the flexion center, Neuflex had 0.188 GPa peak stress at the fixation center of the arm, and in the center of the joint, and the Avanta design had a 5.20 GPa peak stress at the flexion center. The location and concentration of stresses on the models correspond to literature searches for clinical data, showing that the main failure mechanism for these implants is due to primary flexion-extension natural movement of the joint.

关键词： Metacarpo-Phalangeal Joint Phalangeal Joint Finger Prostheses Total Joint Replacement Computational Modeling Swanson Avanta NeuFlex

陕西关中地区农民专业合作社贷款影响因素分析

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贵州农业科学 2014年第2期42卷 253-258页

作者：李坚未赵凯 vo Sy 西北农林科技大学经济管理学院陕西杨凌712100

为了探明农民专业合作社贷款的影响因素,以陕西省关中地区225份农民专业合作社调查问卷为依据,从资产规模、经营能力、财务规范程度、银社关系、社长因素、外部融资环境等方面选取了影响农民专业合作社获得贷款的11个因素,运用多元回归... 详细信息

为了探明农民专业合作社贷款的影响因素,以陕西省关中地区225份农民专业合作社调查问卷为依据,从资产规模、经营能力、财务规范程度、银社关系、社长因素、外部融资环境等方面选取了影响农民专业合作社获得贷款的11个因素,运用多元回归模型分析并检验了这些因素对陕西农民专业合作社获得贷款的实际影响。结果表明:合作社固定资产规模、合作社经营年限、合作社定期向银行报送会计材料、合作社社长工作经历、政府成立专门的担保机构、政府出台合作社贷款政策文件对陕西农民专业合作社实际获得贷款具有影响。

关键词：农民专业合作社贷款影响因素陕西关中

一种紫外-可见光谱检测水质COD预测模型优化方法

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中国环境科学 2015年第2期35卷 478-483页

作者：汤斌赵敬晓魏彪罗继阳 vo Quang Sang 冯鹏米德伶重庆大学光电技术及系统教育部重点实验室重庆400044

针对紫外-可见光谱法检测水质COD预测模型的精度低和收敛速度慢等问题,研究了一种基于粒子群算法联合最小二乘支持向量机(PSO_LSSVM)的水质检测COD预测模型优化方法,并引入主元分析(PCA)算法对模型输入光谱数据进行降维预处理,借以提高... 详细信息

针对紫外-可见光谱法检测水质COD预测模型的精度低和收敛速度慢等问题,研究了一种基于粒子群算法联合最小二乘支持向量机(PSO_LSSVM)的水质检测COD预测模型优化方法,并引入主元分析(PCA)算法对模型输入光谱数据进行降维预处理,借以提高模型的收敛速度.结果表明,利用粒子群(PSO)算法收敛速度快和全局优化能力,优化了最小二乘支持向量机(LSSVM)模型的惩罚因子和核函数参数,避免了人为选择参数的盲目性,克服了传统LSSVM预测模型的精度较低、稳健性较差等缺点.通过以收敛时间、预测平均相对误差(MRE)和均方根误差(RMSE)为评价标准进行评估,输入样本经过PCA降维预处理的PSO_LSSVM模型的预测能力和输入样本未经过降维预处理的LSSVM模型与PSO_LSSVM模型进行了比较分析,输入样本经过PCA降维预处理的PSO_LSSVM模型预测效果最优,且此算法使用C语言实现,易于移植,这为紫外-可见光谱水质COD在线、实时性检测奠定了基础.

关键词：水质COD 紫外-可见光谱法预测模型 PCA PSO_LSSVM

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德国ICE-M多电制电动车组

国外铁道车辆 1993年第6期30卷 10-13页

作者： Martin voβ 张彦儒

介绍为开发欧洲国际高速旅客列车而在德国ICE(城间高速试验列车)基础上研制的ICE—M多电制电动车组。阐述了它的设计特点和主要技术参数。

关键词：电动车组电流制高速列车

Cathepsin D overexpression in the nervous system rescues lethality and Aβ42 accumulation of cathepsin D systemic knockout in vivo

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Acta Pharmaceutica Sinica B 2023年第10期13卷 4172-4184页

作者： Xiaosen Ouyang Willayat Y.Wani Gloria A.Benavides Matthew J.Redmann Hai vo Thomas van Groen Victor M.Darley-Usmar Jianhua Zhang Department of Pathology University of Alabama at BirminghamBirminghamAL 35294USA Department of Cell Developmental and Integrative BiologyUniversity of Alabama at BirminghamBirminghamAL 35294USA Birmingham VA Medical Center University of Alabama at BirminghamBirminghamAL 35294USA

The lysosome is responsible for protein and organelle degradation and homeostasis and the cathepsins play a key role in maintaining protein quality *** D(CTSD),is one such lysosomal protease,which when deficient in humans lead to neurolipofuscinosis(NCL)and is important in removing toxic protein *** studies demonstrated that CTSD germ-line knockout-CtsdKO(CDKO)resulted in accumulation of protein aggregates,decreased proteasomal activities,and postnatal lethality on Day 26±*** of wildtype CTSD,but not cathepsin B,L or mutant CTSD,decreased a-synuclein toxicity in worms and mammalian *** this study we generated a mouse line expressing human CTSD with a floxed STOP cassette between the ubiquitous CAG promoter and the *** crossing with Nestin-cre,the STOP cassette is deleted in NESTIN+cells to allow CTSD overexpression-CTSDtg(CDtg).The CDtg mice exhibited normal behavior and similar sensitivity to subchronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)induced *** breeding CDtg mice with CDKO mice,we found that over-expression of CTSD extended the lifespan of the CDKO mice,partially rescued proteasomal deficits and the accumulation of Aβ42 in the *** new transgenic mouse provides supports for the key role of CTSD in protecting against proteotoxicity and offers a new model to study the role of CTSD enhancement in vivo.

关键词： Cathepsin D transgenic mouse Mitochondrial bioenergetics Apoptosis Cathepsin D knockout mice Dopamine Autophagy Lysosome Life expectancy Behavior

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越南岘港中国客源市场服务营销策略研究

越南岘港中国客源市场服务营销策略研究

作者： vo Minh Hien 兰州理工大学

学位级别：硕士

根据世界旅游理事会(WTTC)2018年旅游经济影响报告,旅游对越南国内生产总值(GDP)的直接和总贡献为5.9%和9.4%,使旅游业成为经济的重点支撑产业之一。2019年越南接待外国游客量达约1800万人次,同比增长16.2%,其中中国游客超过580万人次,... 详细信息

根据世界旅游理事会(WTTC)2018年旅游经济影响报告,旅游对越南国内生产总值(GDP)的直接和总贡献为5.9%和9.4%,使旅游业成为经济的重点支撑产业之一。2019年越南接待外国游客量达约1800万人次,同比增长16.2%,其中中国游客超过580万人次,同比增长15.1%,这是中国游客历年来在越南旅游第二次次突破500万人次,创历史新高,中国也成为了越南最大旅游客源国。岘港市政府在旅游的宣传和营销方面给予了高度的重视,经过几年的努力,在旅游资源的规划、开发、保护和景区管理等方面取得了长足的进步,这也为岘港市增加旅游收入奠定了基础。这些成果也让越来越多的人关注岘港旅游业的发展,越来越多的学者开始研究岘港旅游业的未来发展。在此背景下,利用越南旅游业整体向好的发展趋势,针对庞大的中国游客客源,越南岘港如何把握机遇,大力发展旅游业,继续开发中国客源市场值得探讨和研究。本论文主要研究的是越南岘港对中国旅游客源的市场。本文在7Ps营销组合理论的基础上,以越南岘港为例,介绍了越南岘港的入境旅游市场,分析了影响岘港入境旅游消费的因素,以及越南岘港旅游市场营销所存在的问题。从越南岘港入境旅游市场开发SWOT分析、中国游客市场调查分析、中国游客赴岘港旅游消费行为分析的基础上,提出了一套系统实用的旅游营销7Ps组合策略,包括旅游产品开发设计策略、旅游产品定价策略、旅游营销渠道策略、旅游促销策略、旅游人员管理策略、旅游有形展示策略、旅游营销服务过程策略,尽量弥补岘港旅游营销中的不足。最终,从专业人才、基础设施、行业管理、旅游平台四个方面提出了策略的实施保障。

关键词：越南岘港 SWOT分析 7PS营销策略中国客源市场

软木塞基碳量子点的水热合成及其生物相融荧光成像应用

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新型炭材料 2022年第3期37卷 595-602页

作者： Quang Ngo Khoa Hieu Nguyen Ngoc Bao vo Van Quoc Phuoc vo Thi Ngoc Le Xuan Diem Doc Luong Quang Tri Nguyen Minh Son Le Vu Truong Son Le Van Thanh Ha Che Thi Cam University of Sciences Hue University77 Nguyen HueHueVietnam Faculty of Environmental and Natural Sciences Duy Tan UniversityDa Nang550000Vietnam Institute for Research and Training in Medicine Biology and PharmacyDuy Tan UniversityDa Nang550000Vietnam University of Agriculture and Forestry Hue University102 Phung HungHueVietnam University of Science and Education The University of Da Nang459 Ton Duc ThangLien ChieuDa NangVietnam

以废弃酒瓶软木塞为原料,采用低成本、简单的水热方法合成碳量子点。通过TEM、FTIR、Raman、UV-Vis、PL光谱对碳量子点的结构和光学性能进行分析表征。结果表明,碳量子点的平均直径为6.2±2.7 nm,PL激发谱和碳量子点表面的官能团有关。... 详细信息

以废弃酒瓶软木塞为原料,采用低成本、简单的水热方法合成碳量子点。通过TEM、FTIR、Raman、UV-Vis、PL光谱对碳量子点的结构和光学性能进行分析表征。结果表明,碳量子点的平均直径为6.2±2.7 nm,PL激发谱和碳量子点表面的官能团有关。用硫酸奎宁作为参考,碳量子点的量子效率为1.54%。将获得的碳量子点应用在骨髓间充质干细胞的细胞生物成像上,发现用碳量子点处理后,骨髓间充质干细胞分别在320~380 nm、450~490 nm和450~490 nm范围显示绿色、黄色和红色荧光,表明了碳量子点在荧光成像领域具有潜在的应用价值。

关键词：碳点水热合成荧光荧光图像废酒瓶塞

Advances in endovascular aneurysm management: flow modulation techniques with braided mesh devices

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Stroke & Vascular Neurology 2020年第1期5卷 1-13页

作者： Jessica K Campos Barry Cheaney II Brian V Lien David A Zarrin Chau D vo Geoffrey P Colby Li-Mei Lin Alexander L Coon Department of Neurosurgery University of California Irvine School of MedicineOrangeCaliforniaUSA Oregon Health and Science University School of Medicine PortlandOregonUSA Neurosurgery Johns Hopkins UniversityBaltimoreMarylandUSA Johns Hopkins University School of Medicine BaltimoreMarylandUSA UCLA Neurosurgery Ronald Reagan UCLA Medical CenterLos AngelesCaliforniaUSA Carondelet Neurological Institute St.Joseph's HospitalCarondelet Health NetworkTucsonArizonaUnited States

Flow diverters and flow disruption technology,alongside nuanced endovascular techniques,have ushered in a new era of treating cerebral ***,we provide an overview of the latest flow modulation devices and highlight the... 详细信息

关键词： flow braided hered

Introduction of the special issue on the 10th WESTPAC International Scientific Conference

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Acta Oceanologica Sinica 2019年第1期38卷 I0001-I0001页

作者： Fangli Qiao Si Tuan vo Wenxi Zhu First Institute of Oceanography Ministry of Natural Resources Laboratory for Regional Oceanography and Numerical Modeling Pilot National Laboratory for Marine Science and Technology (Qingdao) Key Laboratory of Marine Science and Numerical Modeling Ministry of Natural Resources Institute of Oceanography Vietnam Academy of Science and Technology IOC Sub-Commission for the Western Pacific Intergovernmental Oceanographic Commission of UNESCO

This special issue is the scientific legacy of the 10th WESTPAC International Scientific Conference, which was sponsored by State Oceanic Administration of China and the Intergovernmental Oceanographic Commission of UNESCO, and organized by the IOC Sub- Commission for the West Pacific (WESTPAC) and the First Institute of Oceanography of China, which was held in Qingdao, China during 17–20 April 2017 with more than 700 participants from 21 countries. During the conference, the international scientific steering committee announced the special issue of Acta Oceanologica Sinica for building a scientific legacy. Forty-five manuscripts were submitted with 20 papers accepted for this special issue.

关键词： special WESTPAC UNESCO