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The bactericidal effect of continuous wave laser with strongly absorbing coating at the fiber tip

Journal of Innovative Optical Health Sciences 2018年第5期11卷 51-58页

作者： Vadim Elagin Anton Smirnov Vladimir Yusupov Alexey Kirillov Nadezhda Ignatova Olga Streltsova Evgeniy Grebenkin vladislav kamensky Institute of Biomedical Technologies Privolzhsky Research Medical University 10/1 Minina Square Nizhny Novgorod 603005Russia Laboratory of Laser Nanomodification of Materials Institute of Applied Physics Russian Academy of Sciences 46 Ulyanova Street Nizhny Novgorod 603950Russia Institute of Photon Technologies of Federal Scientific Research Centre"Crystallography and Photonics"of the Russian Academy of Sciences 2 Pionerskaya Street MoscowTroitsk 108840Russia Department of Innovative Program Institute of Applied Physics Russian Academy of Sciences 46 Ulyanova Street Nizhny Novgorod 603950Russia

The bactericidal effect of laser radiation with a quartz fiber-based transmission system with a strong absorption coating converter against bacteria associated with urological stones has been *** am-negative rod Escherichia coli and the Gram-positive coccus Staphylococcus epi-dermidis,Staphylococcus aureus,Enterococcus faecalis and Enterococcus faecium were used in this *** bacterial species was treated by continuous-wave near infrared laser coupled with bare fiber tip or strongly absorption coating fiber *** treatment,the temperature of bacterial suspension was *** addition,the temperature dist ribution was *** has been shown that using laser with a strongly absorption coating fiber tip results in significant bactericidal *** decrease of the amount of *** and *** was 100%after treatment with an output power of6 W of radiation at a wavelength of 0.97 pum for *** of *** and *** colony-forming unit was reduced to 70%after same *** peak temperature of bacterial suspension was 86℃ after treatment by laser with a strongly absorption coating fiber *** with a strongly absorpt ion coating fiber tip provides large scale hydrodynamic flows directed away from the fiber *** laser with a strongly absorption coating fiber tip has bactericidal *** main role is associated with the effect of high temperature,which,in the form of flow in a liquid medium,afects bacteria.

关键词： Laser strongly absorbing coating bacteria bacterididal efect laserinduced hydrodynamic

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The influence on biotissue laser resection of a strongly absorbing layer at the optical fiber tip

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Journal of Innovative Optical Health Sciences 2016年第5期9卷 15-21页

作者： Daria Kuznetsova Vadim Elagin Maria Karabut Maria Shakhova Vladimir Bredikhin Liudmila Snopova Andrei Shakhov Natalia Sapogova Nikita Bityurin Victor Bagratashvili vladislav kamensky Institute of Biomedical Technologies Nizhny Novgorod State Medical Academy 10/1 Minin and Pozharsky Sq. Nizhny Novgorod 603005Russia Lobachevsky State University of Nizhni Novgorod 23 Gagarin Avenue BLDG 2 Nizhny Novgorod 603950Russia Nizhny Novgorod State Medical Academy 10/1 Minin and Pozharsky Sq. Nizhny Novgorod 603005Russia Institute of Applied Physics Russian Academy of Sciences 46 Ul'yanov StreetNizhny Novgorod 603950Russia Institute on Laser and Information Technologies Russian Academy of Sciences 2 Pionerskaya St. Troitsk 142092Russia

In this paper,we consider a method of laser resection using the silica glass core from which the cladding layer has been removed as the cutting part of a laser *** absorbing layer coating the silica fiber tip markedly alters its biotissue cutting character *** results of histological studies of skin after exposure to a laser scalpel with and without a strongly absorbing coating(SAC)at a wavelength of 097μm show that resection using a coated scalpel is more *** an uncoated scalpel was used,skin injury was more apparent in both its surface spread and the depth of structural damage,resulting in poorer tissue regeneration.

关键词： Laser surgery silica fibers strongly absorbing coating histology

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Comparative Analysis of Biotissue Laser Resection Using Strongly Absorbing Optical Fiber Tips

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Optics and Photonics Journal 2015年第1期5卷 1-5页

作者： Daria S. Kuznetsova Maria M. Karabut Vadim V. Elagin Maria A. Shakhova Vladimir I. Bredikhin Olga S. Baskina Ludmila B. Snopova Andrey V. Shakhov vladislav A. kamensky Lobachevsky State University of Nizhni Novgorod National Research University Nizhny Novgorod Russia Otolaryngology Clinic N.A. Semashko Nizhny Novgorod Regional Clinical Hospital Nizhny Novgorod Russia Institute of Applied Physics of the Russian Academy of Sciences Nizhny Novgorod Russia Central Research Laboratory Nizhny Novgorod State Medical Academy Nizhny Novgorod Russia The Department of Otorhinolaryngology Nizhny Novgorod State Medical Academy Nizhny Novgorod Russia

We present a laser resection technique to be used when biotissue is heated by laser radiation to the temperature of material softening and then moved apart by the lateral edge of the optical fiber with a strongly absorbing tip. The absorbing tip allows the decrease in the power of effective cutting of the laser scalpel at the wavelength of 0.97 μm. And it changes the resection speed as well as the characteristics of the damage of the tissues adjacent to the incision in experiments on model media and experimental animals.

关键词： Laser Resection Silica Fibers Strongly Absorbing Coating Histology

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On the possible ultrasonic inspection of micro-bubbles generated by the optical fiber tip

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Journal of Innovative Optical Health Sciences 2016年第5期9卷 22-29页

作者： V.V.Kazakov A.G.Sanin V.A.kamensky Institute of Applied Physics of the Russian Academy of Sciences 46 Ul'yanov Street 603950Nizhny NovgorodRussia

We demonstrate the possibility of detection and monitoring of bubbles emerging near the tip of an optical fiber by means of ultrasonic *** excitation of bubbles at their resonant frequencies is performed using short ultrasonic pulses having a wide frequency range simulta-neously with their modulation by means of a long pulse of a monochromatic *** method allows detection of bubbles of various *** signal processing method,which allows increased bubble detection accuracy,is proposed for ressearch in envir onments of biological-like medium which show continuous variations in structure and properties when exposed to optical *** method has been demonstrated on model objects:in a liquid and in a biological tissue phantom using various methods of bubble generation(hydrolysis and optical enission).We studied bubble formation by the tip of a fiber of the surgical laser LSP-007/10 "IRE Polus"with a wavelength of 0.97μm coated with a highly absorbing graphite layer.

关键词： Bubble generation ultrasonic inspection of bubbles subharmonic ultrasound modulation laser surgery.

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Noninvasive study of structural and functional features of neonatal skin

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Journal of Innovative Optical Health Sciences 2014年第3期7卷 40-49页

作者： I.L.Shlivko V.A.kamensky M.Y.Kirillin P.D.Agrba O.E.Garanina M.S.Neznakhina D.O.Ellinsky A.S.Maksimova E.V.Donchenko Nizhny Novgorod State Medical Academy 603005 Minin and Pozharsky Square 10/1 Nizhny Nougoro dRussia Institute of Applied Physics R.AS603950 Ulyanou str.46 Nizhny NovugorodRussia Nizhngy Novgorod Research Institute of Traumatology.and Orthopedics 603155 Verkhnevolzhskaya Embankment 18 Nizhny NougorodRussia

In the present paper,we describe the first complex multifocal noninvasive morphological andfunctional study that enabled us to define specific qualitative and quantitative features of neo-natal skin.A complex morphofunctional examination of 10 infants aging from 1 to 28 days wasperformed by optical coherence tomography(OCT)device with a flexible probe at the wavelength of 920 nm with longitudinal resolution of 20μm and transverse resolution of 25μm with simultaneous measurement of skin functional *** OCT images of neonatal thin skinhave organized layered structure with four horizontally oriented *** skin of newbornshas no structure typical for adult skin and no clear transition from the papillary to the ***,we show for the first time to our knowledge that neonatal thick skin differs structurally and functionally from adult ***,it differs by a loose arrangement of stratum corneum squamae and thinner epidermis and papilary layer of *** functionaldifferences are lower transepidermal water loss,localization-dependent humidity,higher ery,thema level,and lower *** principal structural diferences between neonatal andadult skin show that skin structure formation is not completed by the moment of birth.

关键词： Optical coherence tomography skin skin barrier neonate.

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Efficacy and Safety of Nasal Administration of “Na-no-L-DOPA” Based on PLGA Nanoparticles

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Engineering（科研） 2012年第10期4卷 27-29页

作者： I.G. Kondrasheva T.A. Antipova G.G. Barsegyan P.Ye. Gambaryan A.A. Guseva A.A. kamensky Moscow State University Moscow Russia Research Center of Molecular Diagnostics & Therapy Moscow Russia

Inclusion of L-DOPA, the standard Parkinson’s disease medication, into polymeric particles (PLGA) results in optimization the drug metabolism and increasing its bioavailability, significantly increases of physical en... 详细信息

关键词： Nanopaticls L-DOPA Nasal Administration Parkinson’s Disease

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美国联邦政府绩效管理的历史演进与启示

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江苏师范大学学报（哲学社会科学版） 2019年第3期45卷 73-87页

作者： [美]约翰·M·卡门斯基杨媛(校译) IBM政府科技研究中心美国纽约美国行政科学院联邦政府改革小组美国自然科学基金会预算与管理顾问委员会新华人寿保险股份有限公司人力资源部

过去二十年兴起的绩效管理运动改变了美国政府机构内部及机构之间的对话,使其从关注对绩效活动过程和产出的测量,转向关注任务目标的实现。美国绩效管理运动经历了三个阶段:首先,通过开发新的管理流程收集绩效信息;其次,使用更复杂的技... 详细信息

过去二十年兴起的绩效管理运动改变了美国政府机构内部及机构之间的对话,使其从关注对绩效活动过程和产出的测量,转向关注任务目标的实现。美国绩效管理运动经历了三个阶段:首先,通过开发新的管理流程收集绩效信息;其次,使用更复杂的技术分析绩效信息;最后,在绩效信息收集工作的推动下,决策者对绩效信息的需求逐步增加。经过反复试验,美国联邦政府得以实现绩效管理框架的发展和制度化,并借助该框架成功实现了执政者更替时政府管理的平稳过渡。

关键词：绩效管理美国联邦政府绩效信息战略管理循证决策

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多硝基化合物的静电火花感度及其与文献值的对比

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含能材料 1998年第3期6卷 118-122页

作者： Svatopluk ZEMAN Pavel VALENTA Vladimír ZEMAN Jan JAKUBKO Zdeněk kamensky

测定了１５种多硝基化合物的静电火花感度并与文献值进行了对比。同一样品来说不同作者得到的５０％发火概率的ＥＥＳ值不尽相同，其主要原因是不同作者所采用的静电火试验规范不同。但是本实验值与文献值存在着线性关系。

关键词：发火概率多硝基化合物静电火花感度文献值

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老年女性的低舒张压与死亡率：来自妇女健康倡议长寿研究的结果

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中华高血压杂志(中英文) 2023年第5期 500-500页

作者： Haring B McGinn AP kamensky V Allison M Stefanick ML Schnatz PF Kuller LH Berger JS Johnson KC Saquib N Garcia L Richey PA Manson JE Alderman M Wassertheil SS 刘青郑武洪

以往收缩压降压目标不考虑低舒张压水平与心血管病和全因死亡率风险的关系，但这对有合并症的老年人尤为重要。本研究根据妇女健康倡议长寿研究(women’s health initiative long life study, WHILS),分析舒张压水平与老年女性心血管病...

以往收缩压降压目标不考虑低舒张压水平与心血管病和全因死亡率风险的关系，但这对有合并症的老年人尤为重要。本研究根据妇女健康倡议长寿研究(women’s health initiative long life study, WHILS),分析舒张压水平与老年女性心血管病、全因死亡率的关系。方法：研究样本包括7 875名女性，平均年龄79岁，均在2012—2013年随访并测量了血压。

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