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Relaxation of Mechanical Stress in Poly(vinyl alcohol) Cryogels of Different Compositions

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Chinese Journal of Polymer Science 2023年第3期41卷 442-447,I0010页

作者： vladimir n.Manzhai Maria S.Fufaeva Ekaterina S.Kashlach Institute of Petroleum Chemistry of the Siberian Branch of the Russian Academy of Sciences Tomsk 634055Russia

The study presents the experimental results of measurements of the relaxation time of cryogels formed from various colloid-dispersed systems based on a poly(vinyl alcohol) aqueous *** is shown that the value of relaxation time,which characterizes the relationship between the viscosity and elasticity of real bodies,describes the rheological properties of materials more objectively than the traditional assessment of their physical and mechanical characteristics only by the elasticity modulus of the samples.

关键词： Cryogel Relaxation processes Viscoelasticity Rheological properties

树轮记录的阿尔泰山南坡过去304年夏季温度变化及水热配置模式

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第四纪研究 2024年第4期44卷 859-868页

作者：李强刘禹 Olga Solomina 王嘉川 vladimir Matskovsky 宋慧明孙长峰庞文轩闫亚兰蔡秋芳任萌程海全球环境变化研究院西安交通大学陕西西安710049 黄土与第四纪地质国家重点实验室中国科学院地球环境研究所陕西西安710061 Institute of Geography Russian Academy of SciencesMoscow 119017Russia 西安地球环境创新研究院陕西西安710061

阿尔泰山南坡受到西风急流、北冰洋冷湿气流、蒙古-西伯利亚高压和亚洲低压共同影响,形成了当地特有的气候模式;同时,阿尔泰山地区是欧亚沟通的枢纽地带,气候变化对周边人类生产生活以及生态系统影响显著。因此有必要了解阿尔泰山周边... 详细信息

阿尔泰山南坡受到西风急流、北冰洋冷湿气流、蒙古-西伯利亚高压和亚洲低压共同影响,形成了当地特有的气候模式;同时,阿尔泰山地区是欧亚沟通的枢纽地带,气候变化对周边人类生产生活以及生态系统影响显著。因此有必要了解阿尔泰山周边气候变化长期历史,识别气候变化特征,总结规律以应对未来气候变化带来的灾害。本研究利用相关分析发现阿尔泰山南坡西伯利亚落叶松树轮宽度年表与夏季(6~7月)温度呈显著关系(r=0.626,n=58,p<0.001),进而建立一阶线性回归模型方程定量重建了阿尔泰山南坡过去304年(1715~2018年)夏季温度变化。统计结果显示重建序列稳定可靠,并有能力代表大范围的温度变化特征。重建存在5个暖期(1740~1767年、1775~1793年、1837~1847年、1898~1909年、1990~2018年)和5个冷期(1715~1727年、1807~1828年、1848~1858年、1876~1897年、1927~1940年)。虽然自1990年来温度持续上升(1990~2018年温度距平0.33℃),但并未超过1740~1767年的温度(温度距平0.49℃)。结合周边降水重建序列,发现研究区域在过去3个多世纪表现出夏季水热同步的配置模式,即暖湿/冷干模态占主导地位。

关键词：温度重建树轮宽度阿尔泰山西伯利亚落叶松

Analytical solution for a strong free-surface water vortex describing flow in a full-scale gravitational vortex hydropower system

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Water Science and Engineering 2021年第1期14卷 72-79页

作者： vladimir Joel Alzamora Guzman Julie Anne Glasscock Energy Research Group Kadagaya Research Centre for Appropriate TechnologyJunin 12866Peru

Strong free-surface water vortices are found throughout industrial hydraulic systems used for water treatment,flow regulation,and energy *** models using the volumetric flow rate as a model input have generally been semi-empirical,and have tended to have some limitations in terms of the design of practical hydropower *** this study,an analytical model of a strong free-surface water vortex was *** model only requires the water head and geometric parameters as its inputs and calculates the maximum volumetric flow rate,aircore diameter,and rotational *** experimental depthedischarge data from a full-scale gravitational vortex hydropower system,unavailable in the relevant literature,were obtained,and the simulated results showed excellent agreement with the experimental *** data could be used to verify similar models using laboratory-scale physical models in order to investigate the scaling *** contrast to previous models,this model does not assume a constant average velocity across the vortex radius and allows precise calculation of the resultant velocity ***,this model presents advantages in turbine design for energy generation systems.

关键词： Gravitational vortex Velocity measurements Scalability Analytical model Microhydropower

Unfoldomics of prostate cancer： on the abundance and roles of intrinsically disordered proteins in prostate cancer

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Asian Journal of Andrology 2016年第5期18卷 662-672页

作者： Kevin S Landau Insung na Ryan O Schenck vladimir n Uversky DepartmentofMolecularMedicine MorsaniCollegeofMedicineUniversityofSouthFloridaTampaFL33612USA USFHealthByrdAlzheimer'sResearchInstitute MorsaniCollegeofMedicineUniversityofSouthFloridaTampaFlorida33612USA LaboratoryofStructuralDynamics StabilityandFoldingofProteinsInstituteofCytologyRussianAcademyofSciencesStPetersburgRussia

Prostatic diseases such as prostate cancer and benign prostatic hyperplasia are highly prevalent among men. The number of studies focused on the abundance and roles of intrinsically disordered proteins in prostate cancer is rather limited. The goal of this study is to analyze the prevalence and degree of disorder in proteins that were previously associated with the prostate cancer pathogenesis and to compare these proteins to the entire human proteome. The analysis of these datasets provides means for drawing conclusions on the roles of disordered proteins in this common male disease. We also hope that the results of our analysis can potentially lead to future experimental studies of these proteins to find novel pathways associated with this disease.

关键词： intrinsical ly disordered proteins posttranslational mod ifications prostate cancer protein-protein interaction proteomics proteome unfoldome

Arrestins:structural disorder creates rich functionality

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Protein & Cell 2018年第12期9卷 986-1003页

作者： Vsevolod V.Gurevich Eugenia V.Gurevich vladimir n.Uversky Department of Pharmacology Vanderbilt UniversityNashvilleTN 37232USA Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute Morsani College of Medicine University of South FloridaTampaFL 33612USA Institute for Biological Instrumentation Russian Academy of SciencesPushchinoMoscow RegionRussia 142290

Arrestins are soluble relatively small 44-46 kDa proteins that specifically bind hundreds of active phosphorylated GPCRs and dozens of non-receptor partners. There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microtubule-bound. Recent evidence suggests that conformational flexibility in every functional state is the defining characteristic of arrestins. Flexibility, or plasticity, of proteins is often described as structural disorder, in contrast to the fixed conformational order observed in high-resolution crystal structures. However, protein-protein interactions often involve highly flexible elements that can assume many distinct conformations upon binding to different partners. Existing evidence suggests that arrestins are no exception to this rule: their flexibility is necessary for functional versatility. The data on arrestins and many other multi-functional proteins indicate that in many cases, "order" might be artificially imposed by highly non-physiological crystallization conditions and/or crystal packing forces. In contrast, conformational flexibility (and its extreme case, intrinsic disorder) is a more natural state of proteins, representing true biological order that underlies their physiologically relevant functions.

关键词： EPR GPCR nMR arrestin crystal structure disorder protein-protein interactions

High-level intrinsic disorder explains the universality of CLIP binding to diverse MHC class II variants

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Cellular & Molecular Immunology 2018年第1期15卷 76-78页

作者： vladimir n Uversky Yaping n Tu Onyekachi nwogu Shanitra n Butler Michael Ramsamooj George Blanck Department of Molecular Medicine Morsani College of MedicineUniversity of South Floridaand Immunology ProgramTampaFLUSA H.Lee Moffitt Cancer Center and Research Institute TampaFLUSA

MHC class I and II molecules bind peptides that are either recognized as self or as foreign to the immune system via interaction with T-cell *** T-cell receptor makes molecular contacts with the peptide and the MHC molecule in the region of the MHC peptide binding *** MHC class I and II molecules are highly polymorphic,which presumably allows for great diversity of antigen-binding sites over the population,leading to a species that is relatively fit to withstand foreign *** MHC class I molecules,this allelic variation predicts extensive variation in the sequence of peptides able to bind MHC class I molecules,and this is indeed the case.

关键词： explain class intrinsic

Studies of ultrasonic dehydration efficiency

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第4期12卷 247-254页

作者： vladimir n. KHMELEV Andrey V. SHALUnOV Roman V. BARSUKOV Denis S. ABRAMEnKO Andrey n. LEBEDEV Biysk Technological Institute (Branch) Altai State Technical University

The aim of this investigation was to define the effectiveness of non-contact drying using ultrasonic vibrations. Disk radiators were used for carrying out experiments, and a special drying chamber was designed to provide resonant amplification of ultrasonic vibrations (from 130 to 150 dB). Drying of ginseng and other vegetables demonstrated that the application of ultrasonic vibrations reduced power inputs by 20% in comparison with convective drying. It also led to a decrease of 6% in final moisture content, if the duration of drying was constant. The level of intensification of ultrasonic drying was high (up to 50 g for 1 kg of drying material), which helped to lower the temperature of the drying agent and improve the quality of the dried products.

关键词： Drying Ultrasound Vibration system Drying chamber Processing (treatment) of agricultural products

Unveiling the nature of Polar-ring Galaxies from Deep Imaging

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Research in Astronomy and Astrophysics 2022年第11期22卷 34-50页

作者： Aleksandr V.Mosenkov vladimir P.Reshetnikov Maria n.Skryabina Zacory Shakespear Department of Physics and Astronomy N283 ESCBrigham Young UniversityProvoUT 84602USA Central(Pulkovo)Astronomical Observatory Russian Academy of SciencesPulkovskoye Chaussee 65/1196140 St.PetersburgRussia St.Petersburg State University 7/9 Universitetskaya Nab.199034 St.PetersburgRussia

General structural properties and low surface brightness tidal features hold important clues to the formation of *** this paper,we study a sample of polar-ring galaxies(PRGs)based on optical imaging from the Sloan Digital Sky Survey Stripe 82 and other deep *** investigate the deepest images of candidates for PRGs to *** carry out photometric decomposition on the host galaxies and associated polar structures that allows us to derive the structural properties of both *** are able to detect very faint tidal structures around most PRGs in our *** several galaxies,we can directly observe the formation of the polar ring due to merging,which is manifested in debris of the victim galaxy and an arc-like polar structure made up of its *** a few cases,we can discern signs of tidal *** results obtained indicate that the gravitational interaction and merging of galaxies are the most plausible mechanisms for the formation of PRGs.

关键词： data analysis techniques:photometric galaxies:structure

Convective Instability and Appearance of Structured Flows for Diffusion in Multicomponent Gas Mixtures

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Transactions of nanjing University of Aeronautics and Astronautics 2014年第2期31卷 142-146页

作者： vladimir n. Kossov~ Olga V. Fedorenko Yelena A. Dyachenko Kazakh national Pedagogical University Almaty 050100 Republic of Kazakhstan Institute of Experimental and Theoretical Physics al-Farabi Kazakh National University Almaty 050038 Republic of Kazakhstan Kazakh Academy of Transport and Communications names after M. Tynyshpayev Almaty 050012 Republic of Kazakhstan

The main objective of this article is to investigate the behavior of gaseous systems with two and more independent gradients or thermodynamic forces exhibiting complicated behavior,when the convective flows *** existence of structural formations in these systems is shown by the schlieren method and the fast-response *** linear analysis of stability can explain reasons of the appearance of convective instability in multicomponent gas mixtures.

关键词： diffusion instability of mechanical equilibrium theory of stability partial Rayleigh numbers