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Advances in small animal mesentery models for in vivo flow cytometry,dynamic microscopy,and drug screening

World Journal of Gastroenterology 2007年第2期13卷 192-218页

作者： Ekaterina i Galanzha Valery V Tuchin vladimir P Zharov Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States

Using animal mesentery with intravital optical microscopy is a well-established experimental model for studying blood and lymph microcirculation in vivo. Recent advances in cell biology and optical techniques provide the basis for extending this model for new applications, which should generate significantly improved experimental data. This review summarizes the achievements in this specific area, including in vivo label-free blood and lymph photothermal flow cytometry, super-sensitive fluorescence image cytometry, light scattering and speckle flow cytometry, microvessel dynamic microscopy, infrared (iR) angiography, and high-speed imaging of individual cells in fast flow. The capabilities of these techniques, using the rat mesentery model, were demonstrated in various studies; e.g., real-time quantitative detection of circulating and migrating individual blood and cancer cells, studies on vascular dynamics with a focus on lymphatics under normal conditions and under different interventions (e.g. lasers, drugs, nicotine), assessment of lymphatic disturbances from experimental lymphedema, monitoring cell traffic between blood and lymph systems, and high-speed imaging of cell transient deformability in flow. in particular, the obtained results demonstrated that individual cell transportation in living organisms depends on cell type (e.g., normal blood or leukemic cells), the cell’s functional state (e.g., live, apoptotic, or necrotic), and the functional status of the organism. Possible future applications, including in vivo early diagnosis and prevention of disease, monitoring immune response and apoptosis, chemo- and radio-sensitivity tests, and drug screening, are also discussed.

关键词： Lymph microcirculation Transmission digital microscopy Rat mesentery Flow cytometry Photothermal technique

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20%PEG胁迫下评价引进哈萨克斯坦不同春小麦种质苗期的抗旱性

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新疆农业科学 2024年第6期61卷 1352-1360页

作者：王一钊杨其志刘玉秀阿拉依·努尔卡马力 vladimir Shvidchenko 张正茂西北农林科技大学农学院陕西杨凌712100 哈萨克斯坦赛福林农业技术大学阿斯塔纳010000

【目的】研究引进哈萨克斯坦不同春小麦种质的萌发和生理特性,为选育适宜我国西北旱区春小麦品种提供亲本材料。【方法】采用20%聚乙二醇(polyethylene glycol,PEG)高渗溶液模拟干旱胁迫条件,比较分析28份小麦种质(其中引进哈萨克斯坦... 详细信息

【目的】研究引进哈萨克斯坦不同春小麦种质的萌发和生理特性,为选育适宜我国西北旱区春小麦品种提供亲本材料。【方法】采用20%聚乙二醇(polyethylene glycol,PEG)高渗溶液模拟干旱胁迫条件,比较分析28份小麦种质(其中引进哈萨克斯坦春小麦种质25份)苗期的根长、苗长、根鲜/干重、苗鲜/干重、发芽率、发芽势及发芽指数的变化,利用隶属函数、主成分分析综合评价不同春小麦种质苗期抗旱性。【结果】与对照相比,干旱胁迫显著降低种质苗期的根长、苗长、根鲜重、苗鲜/干重、发芽势和发芽率(P<0.05),降低幅度为18.29%~52.17%;显著增加根干重(P<0.05),平均增加了66.67%。各性状间存在不同程度的相关性,大多数性状抗旱系数间存在显著或极显著相关。9个小麦苗期抗旱相关指标可转换为4个(苗鲜/干重、苗长和发芽率)独立的综合指标可作为哈萨克斯坦春小麦苗期耐旱性评价的主效指标。28份供试材料的加权抗旱指数进行聚类分析,5份为抗旱性强种质,17份为抗旱性种质,6份为抗旱性弱种质。【结论】25份引进哈萨克斯坦春小麦种质中有5份种质,苗期具有较强的萌发特性和抗旱能力,适宜在我国西北旱区春小麦育种中提供抗旱亲本材料。

关键词：春小麦引种种质苗期抗旱性隶属函数

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Single and multi domain buckled germanene phases on Al(111)surface

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Nano Research 2019年第12期12卷 2988-2996页

作者： Dmitriy A.Muzychenko Sergey i.Oreshkin vladimir i.Panov Chris Van Haesendonck Andrey i.Oreshkin Faculty of Physics Lomonosov Moscow State University119991 MoscowRussia Sternberg Astronomical institute Lomonosov Moscow State University119234 MoscowRussia Solid-State Physics and Magnetism Section KU LeuvenBE-3001 LeuvenBelgium

The simultaneous formati on of single domain(3×3)and multi domai n(√7×√7)R(±19.1°)germa nene phases on Al(111)surface in thesub-monolayer range was studied using seanning tunneling microscopy(STM)and density functional theory(DFT)based *** results revealed that both germa nene phases nu cleate and grow in dependently from each other and regardless of Al substratetemperature within significantly expanded range Ts=27-200℃.Our results unambiguously showed that STM images with hexagonalcontrast yield correct-resolved structure for both germanene phases,while honeycomb contrast is a result of an artificial tip-induced STM ***-principles calculations suggested atomic models with strongly buckled germanene(2×2)/Al(111)(3×3)and(√3×√3)R30°/Al(111)(√7×√7)R(±19.1°)with one of eight and one of six Ge atoms protruding upward respectively,that consistently describe the experimentally observed STM images both for single and multi domai n surface *** to the DFT based simulati ons both germa nene(2×2)and(√3×√3)R30°superstructures have a stretched lattice strain with respect to the ideal free-standing germa nene by 6.2%and 13.9%,***,numerous small domains separated by domain boundaries in the(√3×√3)R30°/Al(111)(√7×√7)R(±19.1°)germanenephase tend to reduce the surface energy and prevent the formation of extended single domains,in contrast to the(2×2)/Al(111)(3×3)***,our experimental results showed that the nucleation and growth of germa nene on Al(111)surface yield strong modifications of Alsurface even at room temperature(RT),which may be contributed to the formation of Al-Ge alloy due to Ge surface solid-states reactivitythat was ignored in recent *** is already evident from our present findings that the role of Al atoms in the formation of(3×3)and(√7×√7)R(±19.1°)germa nene phases is worthy to be carefully studied in the future,which could be an important knowledge for large-quantityfabrication of germane

关键词： germanene two-dimensional(2D)materials scanning tunneling microscopy density functional theory aluminum

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The Power of China's Railways

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Beijing Review 2024年第7期67卷 48-48页

作者： vladimir Krotov East China Normal University in Shanghai

China is the world's third largest country by total land area,so the development of railways is a key issue in passenger and freight ***,the Chinese railway network is one of the largest in the world and railway infra... 详细信息

关键词： railway continue passenger

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Heat conduction of multilayer nanostructures with consideration of coherent and incoherent phonon transport

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Nano Research 2022年第10期15卷 9492-9497页

作者： Bin Liu Yangyu Guo vladimir i.Khvesyuk Alexander A.Barinov Moran Wang Department of Thermophysics Bauman Moscow State Technical UniversityMoscow 105005Russia institut Lumière Matière UniversitéClaude Bernard Lyon 1-CNRSUniversitéde LyonVilleurbanne 69622France Key Laboratory for Thermal Science and Power Engineering of Ministry of Education and Center for Flexible Electronics Technology Tsinghua UniversityBeijing 100084China

We report a theoretical investigation of coherent-to-incoherent heat conduction in multilayer *** the coherent regime where the phonon motion is quasi-harmonic,the elastic continuum model gives accurate cross-plane thermal conductivity predictions of upper limits and demonstrates that the coherent transport is the result of the interplay between intrinsic wave *** the temperature or system size increases,the phonon dephasing scattering results in the deviation of thermal conductivity from the coherent-limit *** further introducing the incoherence of phonons,we reproduce the classical minimum thermal conductivity,indicating the feasibility of extending the pure wave model into the wave-particle crossing regime.

关键词： GaAs/AlAs superlattices thermal conductivity coherent and incoherent phonon transport continuum model

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Experimental study on hybridization of a PV–TEG system for electrical performance enhancement using heat exchangers,energy,exergy and economic levelized cost of energy(LCOE)analysis

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Clean Energy 2023年第4期7卷 808-823页

作者： Mohammed A.Qasim vladimir i.Velkin Sergey E.Shcheklein Nuclear Power Plants and Renewable Energy Sources Department Ural Federal University620002 YekaterinburgRussia Department of Projects and Engineering Services Ministry of HealthBaghdad 10047Iraq

The concept of employing thermoelectric generators(TEGs)to recover energy from waste heat has gained popularity,with applications that range from milliwatt to kilowatt levels of output *** this study,a hybrid photovoltaic panel and thermoelectric generator(HPVTEG)system consisting of an integrated heat exchanger,a commercial polycrystalline silicon photovoltaic(PV)panel and a commercial bismuth telluride TEG was ***,TE components can be used to cool PV modules,increasing their output power via the Seebeck *** main finding is that the hybrid system has a reduced average temperature of 16.01°*** average power of the stand-alone PV panel is 28.06 W,but that of the HPVTEG system is 32.76 W,which is an increase of 4.7 *** conversion efficiency and power of the hybrid system increased by 16.7%and 16.4%,respectively,compared with a stand-alone PV *** HPVTEG system achieved an average exergy efficiency of 12.79%compared with 10.98%for a stand-alone PV *** to the calculation results,the levelized cost of energy(LCOE)of the stand-alone PV panel can range from 0.06741 to 0.10251 US$/kWh depending on how many days it is in operation,while the LCOE of the HPVTEG system can range from 0.06681 to 0.10160 US$/kWh.

关键词： PV TEG waste heat hybrid system heat exchanger

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Siberian silkmoth outbreaks surpassed geoclimatic barrier in Siberian Mountains

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Journal of Mountain Science 2020年第8期17卷 1891-1900页

作者： KHARUK Viacheslav i. iM Sergei T. SOLDATOV vladimir V. Sukachev institute of Forest Federal Scientific CenterRussian Academy of ScienceSiberian BranchAcademgorodok 50/28Krasnoyarsk660036 Russia Siberian Federal University Svobodny str.79Krasnoyarsk660041 Russia Reshetnev Siberian State University of Science and Technology Krasnoyarsky rabochy str.31Krasnoyarsk660014 Russia Russian Center of Forest Protection Academgorodok 50A/2Krasnoyarsk660036 Russia

Siberian silkmoth(SSM,Dendrolimus sibiricus Tschetv.)is the most important defoliator of Siberian pine(Pinus sibirica Du Tour)and fir(Abies sibirica Ledeb.)***-induced SSM outbreaks are one of the major driving factors of successions within the taiga *** is suggested that climate change impacted the SSM range and life *** analyzed the migration of alpine and northerly SSM outbreak boundaries in Siberia and the impact of the climate variables and topography on the outbreak *** used time-series scenes(multispectral data,and vegetation indexes EVi and NDii)in combination with field studies,climate variables,and GiS *** found that SSM outbreaks in the area of alpine boundary shifted about 370 m uphill since the mid of *** outbreak onset was promoted by increased dryness and active temperatures and decreased root zone moisture content in the spring-early summer *** terrain topography strongly affected SSM outbreak onset and ***,the outbreak was located at the middle elevations on the gentle concave southeastern slopes,which are the favorable insect habitats between *** the outbreak expanded uphill and downhill,to steeper slopes,and both concave and convex *** with elevation range expansion,SSM surpassed its northern historical outbreak boundary:the potential outbreaks’boundary moved about 300 km *** warming contributes to SSM migration into former outbreak free conifer stands located in highlands and at northern latitudes.

关键词： insect outbreaks Remote sensing monitoring insect ranges expansion Siberian silkmoth Forest health Conifer mortality

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树轮记录的阿尔泰山南坡过去304年夏季温度变化及水热配置模式

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第四纪研究 2024年第4期44卷 859-868页

作者：李强刘禹 Olga Solomina 王嘉川 vladimir Matskovsky 宋慧明孙长峰庞文轩闫亚兰蔡秋芳任萌程海全球环境变化研究院西安交通大学陕西西安710049 黄土与第四纪地质国家重点实验室中国科学院地球环境研究所陕西西安710061 institute of Geography Russian Academy of SciencesMoscow 119017Russia 西安地球环境创新研究院陕西西安710061

阿尔泰山南坡受到西风急流、北冰洋冷湿气流、蒙古-西伯利亚高压和亚洲低压共同影响,形成了当地特有的气候模式;同时,阿尔泰山地区是欧亚沟通的枢纽地带,气候变化对周边人类生产生活以及生态系统影响显著。因此有必要了解阿尔泰山周边... 详细信息

阿尔泰山南坡受到西风急流、北冰洋冷湿气流、蒙古-西伯利亚高压和亚洲低压共同影响,形成了当地特有的气候模式;同时,阿尔泰山地区是欧亚沟通的枢纽地带,气候变化对周边人类生产生活以及生态系统影响显著。因此有必要了解阿尔泰山周边气候变化长期历史,识别气候变化特征,总结规律以应对未来气候变化带来的灾害。本研究利用相关分析发现阿尔泰山南坡西伯利亚落叶松树轮宽度年表与夏季(6~7月)温度呈显著关系(r=0.626,n=58,p<0.001),进而建立一阶线性回归模型方程定量重建了阿尔泰山南坡过去304年(1715~2018年)夏季温度变化。统计结果显示重建序列稳定可靠,并有能力代表大范围的温度变化特征。重建存在5个暖期(1740~1767年、1775~1793年、1837~1847年、1898~1909年、1990~2018年)和5个冷期(1715~1727年、1807~1828年、1848~1858年、1876~1897年、1927~1940年)。虽然自1990年来温度持续上升(1990~2018年温度距平0.33℃),但并未超过1740~1767年的温度(温度距平0.49℃)。结合周边降水重建序列,发现研究区域在过去3个多世纪表现出夏季水热同步的配置模式,即暖湿/冷干模态占主导地位。

关键词：温度重建树轮宽度阿尔泰山西伯利亚落叶松

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incubation time fracture criterion for FEM simulations

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Acta Mechanica Sinica 2011年第4期27卷 541-549页

作者： vladimir Bratov institute for Problem in Mechanical Engineering of the Russian Academy of Sciences Bolshoj pr.V.O.61199178St.-PetersburgRussia

The paper is discussing problems connected with embedment of the incubation time criterion for brittle fracture into finite element computational schemes. incubation time fracture criterion is reviewed; practical questions of its numerical implementation are extensively discussed. Several examples of how the incubation time fracture criterion can be used as fracture condition in finite element computations are given. The examples include simulations of dynamic crack propagation and arrest, impact crater formation （i.e. fracture in initially intact media）, spall fracture in plates, propagation of cracks in pipelines. Applicability of the approach to model initiation, development and arrest of dynamic fracture is claimed.

关键词： Fracture dynamics incubation time Crack dy-namics Finite element method Fracture arrest

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Author Correction: iTO-free silicon-integrated perovskite electrochemical cell for light-emission and light-detection

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Opto-Electronic Advances 2024年第3期7卷 50-50页

作者： Maria Baeva Dmitry Gets Artem Polushkin Aleksandr Vorobyov Aleksandr Goltaev vladimir Neplokh Alexey Mozharov Dmitry VKrasnikov Albert GNasibulin ivan Mukhin Sergey Makarov Alferov University Khlopina 8/3St.Petersburg 194021Russia Department of Physics and Engineering ITMO UniversityLomonosova 9St.Petersburg 197101Russia institute of Automation and Control Processes(iACP) Far Eastern Branch of Russian Academy of SciencesUlitsa Radio 5Vladivostok 690041Primorsky KraiRussia Peter the Great St.Petersburg Polytechnic University Polytechnicheskaya 29St.Petersburg 195251Russia Skolkovo institute of Science and Technology Nobel 3Moscow 121205Russia Qingdao innovation and Development Center Harbin Engineering UniversityQingdao 266000China.

Correction to:Opto-Electronic Advances https://***/10.29026/oea.2023.220154 published online 26 April 2023 After the publication of this article1,it was brought to our attention that calculations of the PeLEC device elec-troluminescent(EL)efficiency contained a mistake,leading to an inaccurate quantity *** device’s maxim-um EL efficiency constitutes not‘~120 klm/W’but‘4.3 lm/W’*** details are listed below.

关键词： value. perovskite listed

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