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First Serological Evidence on Endemicity of HEV Infection in Wild Boar(Sus scrofa) Populations from Portugal

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Virologica Sinica 2018年第2期33卷 197-200页

作者： Daniel Goncalves Joao pereira-Vaz vitor Duque Victor Bandeira Carlos Fonseca Ana Donato Cristina Luxo Ana Miguel Matos Laboratory of Virology Faculty of Pharmacy University of Coimbra 3000-548 Coimbra Portugal Laboratory of Molecular Biology Clinical Pathology UnitHospital and University Centre of Coimbra3000-602 Coimbra Portugal Infectious Diseases Department Hospital and University Centre of Coimbra 3000-075 Coimbra Portugal Biology Department and CESAM University of Aveiro3810-193 Aveiro Portugal Clinical Laboratory Faculty of Pharmacy University of Coimbra 3000-548 Coimbra Portugal Research Centre on Chemical Processes Engineering and Forest Products (CIEPQF) Faculty of Pharmacy University of Coimbra 3030-790 Coimbra Portugal

Increasing number of hepatitis E virus（HEV）infection has been described in industrialized countries,with infection occurring as a sporadic disease,usually associated with travel to endemic regions or small outbreaks... 详细信息

关键词：感染 HEV 血清学葡萄牙野猪证据特性人口

Diagnostic neuroradiology:Ready for the neurointerventional age?

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World Journal of Radiology 2012年第9期4卷 401-404页

作者： Karl-Olof Lvblad vitor Mendes pereira Service Neuro-diagnostique et Neuro-interventionnel Geneva University Hospitals

Acute cerebral ischemia or stroke is currently considered an emergency for which therapeutic options are available if the therapeutic window of 4.5 h is *** modalities have progressed greatly over the last few decades,rendering ischemia detectable in the first hours after the ***,in order for treatment to be efficacious it is necessary to speed up all the processes before the start of ***,one must decrease the time to arrival at the hospital and to the radiological method that is to be employed(be it computed tomography or magnetic resonance imaging);only then will the medical or interventional techniques available fulfill their potential.

关键词： Stroke Interventional neuroradiology Thrombolysis Magnetic resonance imaging Computed tomography

Interventional neuroradiology of stroke, still not dead

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World Journal of Radiology 2013年第12期5卷 450-454页

作者： vitor Mendes pereira Karl-Olof Lvblad Department of Diagnostic and Interventional Neuroradiology Geneva University Hospitals

Since the National Institute of Neurological Disorders and Stroke trial,intravenous thrombolysis has been gaining wide acceptance as the modality of treatment for acute embolic stroke,with a current therapeutic window of up to 4.5 *** imaging[with either magnetic resonance imaging(MRI)or computed tomography(CT)]and interventional techniques(thrombolysis and/or thrombectomy)have since improved and provided us with additional imaging of the penumbra using CT or MRI and more advanced thrombolysis or thrombectomy strategies that have been embraced in many centers dealing with patients with acute cerebral *** techniques,however,have come under scrutiny due to their accrued healthcare costs and have been questioned following major recent *** studies basically showed that interventional techniques were not superior to the traditional intravenous thrombolysis techniques and that penumbra imaging could not determine what patients would benefit from more aggressive(i.e.,interventional)*** discuss this in the light of the latest developments in both diagnostic and interventional neuroradiology and point out why further studies are needed in order to define the right choices for patients with acute ***,these studies were in part conducted with suboptimal patient recruitment strategies and did not always use the latest interventional techniques available ***,while these studies may have raised some relevant questions,at the same time,definitive answers have not been given,in our opinion.

关键词： Stroke Interventional neuroradiology thrombolysis Magnetic resonance imaging Computed tomography

Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core(ANGEL-ASPECT):protocol of a multicentre randomised trial

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Stroke & Vascular Neurology 2023年第2期8卷 169-174页

作者： Xiaochuan Huo Gaoting Ma Xuelei Zhang Yuesong Pan Xu Tong Dapeng Sun Liping Liu Yilong Wang David S Liebeskind Yongjun Wang vitor Mendes pereira Zeguang Ren Zhongrong Miao Department of Interventional Neuroradiology Beijing Tiantan HospitalBeijingChina Department of Neurology Beijing Tiantan HospitalBeijingChina Clinical Research Center Capital Medical UniversityInstitute of Brain DisordersBeijingChina China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalBeijingChina Department of Neurology University of CaliforniaLos AngelesCaliforniaUSA Division of Neurosurgery Department of SurgerySt Michael's HospitalUniversity of TorontoTorontoOntarioCanada Department of Neurosurgery The Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhouChina

Background The benefit of stroke thrombectomy for large infarct core still lacks robust randomised controlled *** To demonstrate the design of a clinical trial on endovascular therapy for acute anterior circulation large vessel occlusion(LVO)patients with large infarct core *** ANGEL-ASPECT is a multicentre,prospective,randomised,open-label,blinded End-point trial to evaluate whether best medical management(BMM)combined with endovascular therapy improves neurological functional outcomes as compared with BMM alone in acute LVO patients with Alberta Stroke Program Early CT Score(ASPECTS)of 3-5 on non-contrast CT or infarct core volume range of 70-100 mL(defined as rCBF<30%on CT perfusion or ADC<620 on MRI)up to 24 hours from symptom onset or last seen *** outcomes The primary efficacy outcome is 90(±7)days modified Rankin *** intracranial haemorrhage within 48 hours from randomisation is the primary safety *** The ANGEL-ASPECT trial will screen patients with large infarct core(ASPECTS 3-5 or 70-100 mL)through image evaluation criteria within 24 hours and explore the efficacy and safety of endovascular therapy compared with BMM.

关键词： patients infarct acute

Simulated Experiments for Teaching Mutually-Coupled Circuits CAD Techniques Using Analytic and Finite Element Solutions

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Journal of Electromagnetic Analysis and Applications 2017年第11期9卷 183-202页

作者： Antonio Flavio Licariao Nogueira vitor Horbe pereira da Costa Rodolfo Lauro Weinert Santa Catarina State University JoinvilleBrazil

The paper describes an approach to teaching mutually-coupled circuits CAD techniques to undergraduate students pursuing a degree course in electrical engineering or physics, and explains how a series of simulated experiments may be incorporated into the existing subjects. The simulated experiments make use of a two-dimensional open-access software based on the finite-element method. At the laboratory meetings, the students learn how to set up field problems for solution, and how to examine the results. Simulation tasks based on three axisymmetric open-boundary problems are used to introduce different numeric techniques to compute inductance and magnetic forces. The paper takes the reader to a step-by-step simulation journey, and provides all the basic elements required for further exploration of axially-symmetric systems.

关键词： Electromagnetic Engineering Education Finite Element Method Inductance Magnetic Forces Simulation Software

Case report of a criminal dismemberment in Northeast Brazil

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Forensic Sciences Research 2022年第4期7卷 637-642页

作者： Evelyne Pessoa Soriano Maria do Socorro Dantas de Araújo Francisca de Assis Nascimento pereira Francisca Divina Silveira de Melo Cristiane Helena da Silva Barbosa Freire Marcus vitor Diniz de Carvalho Medico-legal Institute of João Pessoa ParaíbaBrazil Faculty of Dentistry(FOP) Center for Studies in Forensic Anthropology(CEAF)University of Pernambuco(UPE)RecifeBrazil

Several decomposed body parts were received for examination by the Forensic Anthropology section of the Medico-legal Institute of João Pessoa,Paraíba,*** portions of the lower and upper limbs,ribs,vertebrae,and a skull were thoroughly *** biological profile indicated a male individual with an estimated age range between 23 and 57 years and a mean age of 35.2 years(SD=9.4;phase IV,Suchey-Brooks).The skeleton showed injuries caused by sharp force and sharp-blunt force trauma that affected all body ***,the lesions are mainly in the diaphyseal segments of the long bones,sacrum,pelvis,mandible,maxilla,scapulae,sternum,vertebrae,the distal epiphysis of the left fibula,and the distal epiphysis of the left tibia displayed characteristics compatible with injuries produced *** was not possible to determine the cause of *** resulted in a positive *** of common difficulties faced in forensic practice,it is often not possible for forensic anthropologists to go to the crime scene,X-ray or body scanners are frequently unavailable,and the victim’s medical and/or dental records are sometimes *** difficulties make identification ultimately depend on genetic analysis,which is more time-consuming than other identification *** this,bone fragment examination in dismemberment cases is a complex *** Anthropology can shed light on cases involving the identification of dismembered remains,which are challenging because of the number of traumatic injuries,as well as different injury patterns,on bones.

关键词： Forensic sciences forensic anthropology dismemberment human identification

Evidence-based medicine: An update on treatments for peritoneal dialysis-related peritonitis

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World Journal of Nephrology 2015年第2期4卷 287-294页

作者： Pasqual Barretti Joo vitor pereira Doles Douglas Gonalves Pinotti Regina Paolucci El Dib Department of Internal Medicine Botucatu Medical SchoolUNESP Botucatu Medical School UNESP Department of Anesthesiology Botucatu Medical SchoolUNESP

Peritonitis continues to be a major complication of peritoneal dialysis （PD）, and adequate treatment is crucial for a favorable outcome. There is no consensus regarding the optimal therapeutic regimen, and few prospective controlled studies have been published. The objectiveof this manuscript is to review the results of PD peritonitis treatment reported in narrative reviews, systematic reviews, and proportional meta-analyses. Two narrative reviews, the only existing systematic review and its update published between 1991 and 2014 were included. In addition, we reported the results of a proportional meta-analysis published by our group. Results from systematic reviews of randomized control trials （RCT） and quasi-RCT were not able to identify any optimal antimicrobial treatment, but glycopeptide regimens were more likely to achieve a complete cure than a first generationcephalosporin. Compared to urokinase, simultaneous catheter removal and replacement resulted in better outcomes. Continuous and intermittent IP antibiotic use had similar outcomes. Intraperitoneal antibiotics were superior to intravenous antibiotics in reducing treatment failure. In the proportional meta-analysis of RCTs and the case series, the resolution rate （86%） of ceftazidime plus glycopeptide as initial treatment was signifcantly higher than frst generation cephalosporin plus aminoglycosides （66%） and glycopeptides plus aminoglycosides （75%）. Other comparisons of regimens used for either initial treatment or treatment of gram-positive rods or gram-negative rods did not show statistically significant differences. The superiority of a combination of a glycopeptide and a third generation cephalosporin was also reported by a narrative review study published in 1991, which reported an 88% resolution rate.

关键词： Peritonitis Peritoneal dialysis Antibiotic Treatment

Treatment practice of vasospasm during endovascular thrombectomy: an international survey

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Stroke & Vascular Neurology 2024年第5期9卷 490-496页

作者： Jessica Jesser Thanh Nguyen Adam A Dmytriw Hiroshi Yamagami Zhongrong Miao Louisa Johanna Sommer Andrea Stockero Johannes Alex Rolf Pfaff Johanna Ospel Mayank Goyal Aman B Patel vitor Mendes pereira Uta Hanning Lukas Meyer Wim H van Zwam Martin Bendszus Martin Wiesmann Markus Möhlenbruch Charlotte Sabine Weyland Neuroradiology University Hospital HeidelbergHeidelbergGermany Neurology Boston University School of MedicineBostonMassachusettsUSA St.Michael's Hospital Departments of Medical Imaging and NeurosurgeryNeurovascular CenterUniversity of TorontoTorontoOntarioCanada Neuroendovascular Program Harvard Medical SchoolMassachusetts General HospitalBostonMassachusettsUSA Stroke Neurology National Hospital Organization Osaka National HospitalOsakaJapan Department of Interventional Neuroradiology Beijing Tiantan HospitalBeijingChina Neuroradiology University Hospital AachenAachenGermany University Insitute for Neuroradiology at PMU Uniklinikum Salzburg—Christian-Doppler-KlinikSalzburgAustria Departments of Diagnostic Imaging and Clinical Neurosciences University of CalgaryCalgaryAlbertaCanada Neuroendovascular Program Massachusetts General HospitalBostonMassachusettsUSA Department of Neurosurgery Unity Health TorontoTorontoOntarioCanada Universitatsklinikum Hamburg Eppendorf Klinik und Poliklinik fur Neuroradiologische Diagnostik und Intervention HamburgGermany Diagnostic and Interventional Neuroradiology Universitatsklinikum Hamburg Eppendorf Klinik und Poliklinik fur Neuroradiologische Diagnostik und InterventionHamburgGermany Radiology Maastricht University Medical CenterMaastrichtThe Netherlands

Background and aim The clinical importance and management of vasospasm as a complication during endovascular stroke treatment(EVT)has not been well *** sought to investigate current expert opinions in neurointervention and therapeutic strategies of iatrogenic vasospasm during *** We conducted an anonymous international online survey(4 April 2023 to 15 May 2023)addressing treatment standards of neurointerventionalists(NIs)practising *** illustrative cases of patients with vasospasm during EVT were *** study groups were compared according to the NI’s opinion regarding the potential influence of vasospasm on patient outcome after EVT using descriptive *** In total,534 NI from 56 countries responded,of whom 51.5%had performed>200 *** was considered a complication potentially influencing the patient’s outcome by 52.6%(group 1)whereas 47.4%did not(group 2).Physicians in group 1 more often added vasodilators to their catheter flushes during EVT routinely(43.7%vs 33.9%,p=0.033)and more often treated severe large-vessel vasospasm with vasodilators(75.3%vs 55.9%;p<0.001),as well as extracranial vasospasm(61.4%vs 36.5%,p<0.001)and intracranial medium-vessel vasospasm(27.1%vs 11.2%,p<0.001),compared with group *** case of a large-vessel vasospasm and residual and amenable medium-vessel occlusion during EVT,the study groups showed different treatment *** 2 continued the EVT immediately more often,without initiating therapy to treat the vasospasm first(9.6%vs 21.1%,p<0.001).Conclusion There is disagreement among NIs about the clinical relevance of vasospasm during EVT and its *** was a higher likelihood of use of preventive and active vasodilator treatment in the group that perceived vasospasm as a relevant complication as well as differing interventional strategies for continuing an EVT in the presence of a large-vessel vasospasm.

关键词： survey continued routine

An Optimized Divide-and-Conquer Algorithm for the Closest-Pair Problem in the Planar Case

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Journal of Computer Science & Technology 2012年第4期27卷 891-896页

作者： José C.pereira Fernando G.Lobo Department of Electronics and Computer Science University of AlgarveCampus de Gambelas8005-139 FaroPortugal Center for Environmental and Sustainability ResearchCampus de Caparica2829-516 CaparicaPortugal

We present an engineered version of the divide-and-conquer algorithm for finding the closest pair of points, within a given set of points in the XY-plane. For this version of the algorithm we show that only two pairwise comparisons are required in the combine step, for each point that lies in the 25-wide vertical slab. The correctness of the algorithm is shown for all Minkowski distances with p ≥ 1. We also show empirically that, although the time complexity of the algorithm is still O（n lgn）, the reduction in the total number of comparisons leads to a significant reduction in the total execution time, for inputs with size sufficiently large.

关键词： geometrical problem and computation closest-pair problem Basic-2 algorithm