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Load Forecasting for Control of the Use of Transmission System for Electric Distribution Utilities

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Journal of Energy and Power Engineering 2013年第1期7卷 139-147页

作者： vitor hugo ferreira Alexandre Rasi Aoki Silvio Michel de Rocco Electrical Engineering Department Fluminense Federal University (UFF) Niter6i 24210-240 Brazil Electric and Electronic Department Institute of Technology for Development (LACTEC) Curitiba 80215-090 Brazil Companhia Paranaense de Energia (COPEL) Curitiba 80420-170 Brazil

The Brazilian electric sector reform established that the remuneration of distribution utilities must be through the management of their systems. This fact increased the necessity of control and management of load flows through the connection points between the distribution systems and the basic grid as a function of the contracted amounts. The objective of this control is to avoid that these flows exceed some thresholds along the contracted values, avoiding monetary penalties to the utility or unnecessary amounts of contracted flows that overrates the costumers. This question highlights the necessity of forecast the flows in these connection points in sufficient time to permit the operator to take decisions to avoid flows beyond the contracted ones. In this context, this work presents the development of a neural network based load flow forecaster, being tested two time-series neural models： support vector machines and Bayesian inference applied to multilayered perceptron. The models are applied to real data from a Brazilian distribution utility.

关键词： Load forecasting artificial neural networks complexity control input selection Bayesian methods support vector machines.

Nutritional supplements use in high-performance athletes is related with lower nutritional inadequacy from food

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Journal of Sport and Health Science 2016年第3期5卷 368-374页

作者： Mónica Sousa Maria J.Fernandes Pedro Carvalho José Soares Pedro Moreira vitor hugo Teixeira Centre of Research Education Innovation and Intervention in Sport Faculty of Sport University of Porto Faculty of Nutrition and Food Sciences University of Porto Research Centre on Physical Activity Health and Leisure Faculty of Sport University of Porto

Background: The use of nutritional supplements(NS) among athletes is widespread. However, little is known about the relationship between nutritional adequacy and NS usage. The aims of this study were to evaluate the NS usage and to compare the nutritional intake from food and prevalence of micronutrient inadequacy(PMI) between NS users and ***: Portuguese athletes from 13 sports completed an NS usage questionnaire and a semi-quantitative food-frequency questionnaire assessing information over the previous 12 months. The estimated average requirement cut-point method was used to calculate PMI. General linear models were used to compare nutritional intake and NS usage. Chi-squared tests and logistic regression were performed to study, respectively,relationships and associations between PMI and NS ***: From the 244 athletes(66% males, 13–37 years), 64% reported NS usage. After adjustment, NS users showed a higher intake from food(p < 0.05), for at least 1 gender, for energy, and for 7 of the 17 studied nutrients. The highest PMI were seen for vitamins D and E, calcium, folate,and magnesium. After adjustment, NS users, irrespective of gender, reported lower PMI for calcium(OR = 0.28, 95%CI: 0.12–0.65), and female users for magnesium(OR = 0.06, 95%CI: 0.00–0.98).Conclusion: Athletes using NS reported a higher nutritional intake from food, and a lower PMI for several nutrients. Perhaps, those who were taking NS were probably the ones who would least benefit from it.

关键词： Carbohydrates Minerals Proteins Sport Vitamins

Improvement in varistor properties of CaCu_(3)Ti_(1)O_(12) ceramics by chromium addition

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Journal of Materials Science & Technology 2020年第6期41卷 12-20页

作者： Edson Cezar Grzebielucka Joao Frederico Haas Leandro Monteiro Eder Carlos ferreira de Souza Christiane Philippini ferreira Borges Andrévitor Chaves de Andrade Eloísa Cordoncillo Héctor Beltrán-Mir Sandra Regina Masetto Antunes Programa Pós-Graduacao em Química Aplicada Universidade Estadual de Ponta GrossaAv.Gen.Carlos Cavalcanti 474884.030-000Ponta GrossaParanáBrazil Programa de Pós-Graduacao em Ciências/Física Universidade Estadual de Ponta GrossaAv.Gen.Carlos Cavalcanti 474884.030-000Ponta GrossaParanáBrazil Dpto.de Química Inorgánica y Orgánica Universitat Jaume IAv.de Vicent Sos Baynats/n12071Castellón de la PlanaSpain

The effect of chromium addition on the structure and electrical properties of CaCu3Ti4O12 is *** based on the formula CaCu3Ti4-xCrxO12-σ(x = 0, 0.025, 0.050 and 0.075 mol%) are prepared by solid-state reaction. Pellets sintered at 1070℃ for 12 h are characterised by X-ray diffraction, scanning electron microscopy/energy dispersive spectroscopy and impedance spectroscopy. Current densityelectric field, dielectric loss and permittivity measurements are also carried out. Rietveld refinement showed the substitution of Cr(Ⅲ) on the Ti(Ⅳ) site, with the maximum substitution for x = 0.025 mol%.The generation of electrical defects in the grain boundary region by chromium doping is responsible for increasing the electric breakdown field strength and nonlinearity coefficient at room temperature from 1723 V/cm and 5.29 for x = 0 mol% to 3431 V/cm and 8.16 for x = 0.025 mol%. This composition shows the greatest improvement in ceramic varistor parameters.

关键词： CCTO Structural analysis Impedance Varistor Rietveld

The VILMA intelligent vehicle:an architectural design for cooperative control between driver and automated system

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Journal of Modern Transportation 2018年第3期26卷 220-229页

作者： Olmer Garcia Giovani Bernardes vitor Janito Vaqueiro ferreira Pablo Siqueira Meirelles Arthurde Miranda Neto Universidad de Bogota Jorge Tadeo Lozano BogotaColombia Robotics Intelligent and Complex Systems(RobSIC)LabUniversidade Federal de Itajuba′(UNIFEI)ItabiraMGBrazil Autonomous Mobility Lab at the Universidade Estadual de Campinas(UNICAMP)CampinasSP 13083-860Brazil Terrestrial Mobility Lab at the Universidade Federal de Lavras (UFLA)LavrasMG 37200-000Brazil

Intelligent autonomous vehicles have received a great degree of attention in recent years. Although the technology required for these vehicles is relatively advanced, the challenge is firstly to ensure that drivers can understand the capabilities and limitations of such systems and secondly to design a system that can handle the interaction between the driver and the automated intelligent system. In this study, we describe an approach using different strategies for an autonomous system and a driver to drive a vehicle cooperatively. The proposed strategies are referred to as cooperative planning and control and determine when and how the path projected by the autonomous system can be changed safely by the driver to a path that he wishes to follow. The first phase of the project is described, covering the design and implementation of an autonomous test vehicle. Experiments are carried out with a driver to test the cooperative planning and control concepts proposed here.

关键词： Autonomous vehicles Embedded systems Cooperative systems Visual servoing

Nanoparticle-encapsulated retinoic acid for the modulation of bone marrow hematopoietic stem cell niche

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Bioactive Materials 2024年第4期34卷 311-325页

作者： Emanuel Quartin Susana Rosa Sara Gonzalez-Anton Laura Mosteo Lopez vitor Francisco Delfim Duarte Cristina Lo Celso Ricardo Pires das Neves Lino ferreira CNC-Center for Neuroscience and Cell Biology CIBB-Centre for Innovative Biomedicine and BiotechnologyUniversity of Coimbra3004-517CoimbraPortugal IIIUC-Institute of Interdisciplinary Research University of Coimbra3004-517CoimbraPortugal Faculty of Medicine University of Coimbra3004-517CoimbraPortugal Department of Life Sciences Imperial College LondonSouth Kensington CampusThe Francis Crick InstituteLondonUK Haematopoietic Stem Cell Laboratory The Francis Crick InstituteLondonUK Instituto de Investigação e Inovação em Saúde(i3S) University of PortoPortoPortugal Department of Biomedicine Faculdade de Medicina da Universidade do Porto(FMUP)PortoPortugal Department of Onco-Hematology Instituto Português de Oncologia(IPO)-PortoPortoPortugal

More effective approaches are needed in the treatment of blood cancers,in particular acute myeloid leukemia(AML),that are able to eliminate resistant leukemia stem cells(LSCs)at the bone marrow(BM),after a chemotherapy session,and then enhance hematopoietic stem cell(HSC)engraftment for the re-establishment of the HSC ***,we investigate whether light-activatable nanoparticles(NPs)encapsulating all-trans-retinoic acid(RA^(+)NPs)could solve both *** in vitro results show that mouse AML cells transfected with RA^(+)NPs differentiate towards antitumoral M1 macrophages through RIG.1 and OASL gene *** in vivo results further show that mouse AML cells transfected with RA^(+)NPs home at the BM after transplantation in an AML mouse *** photo-disassembly of the NPs within the grafted cells by a blue laser enables their differentiation towards a macrophage *** macrophage activation seems to have systemic anti-leukemic effect within the BM,with a significant reduction of leukemic cells in all BM compartments,of animals treated with RA^(+)NPs,when compared with animals treated with empty *** a separate group of experiments,we show for the first time that normal HSCs transfected with RA^(+)NPs show superior engraftment at the BM niche than cells without treatment or treated with empty *** is the first time that the activity of RA is tested in terms of long-term hematopoietic reconstitution after transplant using an in situ activation approach without any exogenous priming or genetic conditioning of the transplanted ***,the approach documented here has the potential to improve consolidation therapy in AML since it allows a dual intervention in the BM niche:to tackle resistant leukemia and improve HSC engraftment at the same time.

关键词： Light Nanoparticles Retinoic acid Leukemia M1 macrophages Drug delivery

Alpha-1 antitrypsin deficiency and Pi^(*)Z allele as important co-factors in the development of liver fibrosis

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World Journal of Hepatology 2024年第8期16卷 1099-1110页

作者： Ana Isabel ferreira Catarina Guimarães vitor Macedo Silva Sofia Xavier Joana Magalhães JoséCotter Department of Gastroenterology Hospital da Senhora da Oliveira-GuimarãesGuimarães 4835-044Portugal Life and Health Sciences Research Institute School of MedicineUniversity of MinhoBraga 4710-057Portugal Life and Health Sciences Research Institute/3B’s PT Government Associate LaboratoryBraga 4710-057Portugal Department of Pulmonology Hospital Senhora da Oliveira-GuimarãesGuimarães 4835-044Portugal

BACKGROUND Alpha-1 antitrypsin deficiency(AATD)is a codominant autosomal hereditary condition that predisposes patients to the development of lung and/or liver disease,and Pi*Z allele is the most clinically relevant *** To evaluate the impact of clinical parameters and AATD phenotypes,particularly the Pi*Z allele,in liver *** Cross-sectional cohort study including consecutive patients with AATD followed in Pulmonology or Hepatology *** Included 69 patients,49.3%had Pi*MZ phenotype and 10.1%Pi**** age≥55 years,age at diagnosis≥41 years and AAT at diagnosis<77 mg/dL predicted a nonalcoholic fatty liver disease fibrosis score(NFS)not excluding advanced fibrosis[area under the curve(AUC)=0.840,P<0.001;AUC=0.836,P<0.001;AUC=0.681,P=0.025].An age≥50 years and age at diagnosis≥41 years predicted a fibrosis-4 index of moderate to advanced fibrosis(AUC=0.831,P<0.001;AUC=0.795,P<0.001).Patients with hypertension,type 2 diabetes mellitus(DM),dyslipidaemia,metabolic syndrome,and regular alcohol consumption were more likely to have a NFS not excluding advanced fibrosis(P<0.001,P=0.002,P=0.008,P<0.001,P=0.033).Patients with at least one Pi*Z allele and type 2 DM were 8 times more likely to have liver stiffness measurement≥7.1 kPa(P=0.040).CONCLUSION Risk factors for liver disease in AATD included an age≥50 years,age at diagnosis≥41 years,metabolic risk factors,regular alcohol consumption,at least one Pi*Z allele,and AAT value at diagnosis<77 mg/*** created an algorithm for liver disease screening in AATD patients to use in primary care,selecting those to be referred to Hepatology consultation.

关键词： Alpha-1 antitrypsin deficiency Liver fibrosis Nonalcoholic fatty liver disease fibrosis score Fibrosis-4 index Liver stiffness measurement

-765G > C COX-2 polymorphism may be a susceptibility marker for gastric adenocarcinoma in patients with atrophy or intestinal metaplasia

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World Journal of Gastroenterology 2006年第34期12卷 5473-5478页

作者： Carina Pereira hugo Sousa Paula ferreira Maria Fragoso Luís Moreira-Dias Carlos Lopes Rui Medeiros Mário Dinis-Ribeiro Molecular Oncology Group Portuguese Institute of Oncology of Porto Portugal and ICBAS Abel Salazar Institute for the Biomedical Sciences Porto Portugal Oncology Department Portuguese Institute of Oncology of Porto Portugal Gastroenterology Department Portuguese Institute of Oncology of Porto Portugal and Cintesis / Faculty of Medicine University of Porto Porto Portugal

AIM： To investigate the relationship between the -765G 〉 C COX-2 polymorphism and the development of different gastric lesions： atrophy or intestinal metaplasia and gastric adenocarcinoma. METHODS： A cross-sectional study was performed involving 320 Portuguese individuals （210 without evidence of neoplastic disease, 73 patients with gastric adenocarcinomas and 37 with atrophy or intestinal metaplasia） using a PCR-RFLP method.RESULTS： -765C allele was overrepresented in the patients with gastric adenocarcinoma （51%） when compared either with the control group （38%） or patients with atrophy or intestinal metaplasia （27%）. Callele was found to be very common in our population （0.22）, and a multivariate logistic regression analysis revealed nearly 3-fold increased risk for the progression to gastric adenocarcinoma in patients with atrophy or intestinal metaplasia carrying the -765C allele （OR = 2.67, 95% CI = 1.03-6.93; P = 0.04）.CONCLUSION： -765C carrier status should be considered as another susceptibility marker for gastric adenocarcinoma development in patients with atrophy or intestinal metaplasia.

关键词： Gastric adenocarcinoma Atrophy Intestinal metaplasia COX-2 Polymorphism PCR-RFLP Pharmacogenomic

Organizational Trouble Shooting through Integration between the Theory of the Restrictions Thinking Process and Lean Tools

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Journal of Civil Engineering and Architecture 2014年第6期8卷 738-745页

作者： Tatiana Gondim do Amaral vitor hugo Martins Resende Department of Post Graduate Degree Program in Geotechnical Civil Construction and Structure (PPGECON) FederalUniversity of Goidts Goidnia 74886044 Brazil Department of Engineering Catholic University of Golds Goiania 74605-220 Brazil

The theory of constraints thinking process, created by Israeli physicist Eliyahu M. Goldratt, has emerged as a tool for achieving competitive advantage. Many researches also focused on the application of lean thinking developed by Toyota and proposed by Ohno. This philosophy has been proven to be effective in several production processes. This paper aims to propose a method of problem solving through the integration of theory of constraints thinking process and the principles of lean production. As a tool for problem identification, the method defends the use of current reality tree and, to solve problems, the lean thinking tools, proposed by Picchi. The developed method was implemented in a contractor. The research methodology was research-action. Among the results, there was a realistic diagnosis about the core problems in company. According to this, the core problem of the contractor is “the lack of commitment of manpower” that results in the main problem “the financial loss”. The principle of perfection was verbalized as a proposal to solve the problems and the tools to be implemented for solving problems were “commitment of senior management to employees” and “simplicity in communication”.

关键词： Commitment people culture change agreement theory.

Integration of Theory of Constraints Thinking Process and Lean Production for Troubleshooting on a Contractor

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Journal of Civil Engineering and Architecture 2015年第11期9卷 1279-1293页

作者： vitor hugo Martins e Resende Tatiana Gondim do Amaral School of Engineering Pontifical Catholic University of Goiás Goiania 74605-010 Brazil Department of Civil Engineering Federal University of Goiás Goiania 74605-220 Brazil

The thinking process of TOC （Theory of Constraints） was an important consolidated tool to the systematization of the companies＇ necessities because of its competitive advantage. The lean thinking proposed by Taiichi Ohno and developed by Toyota Company has been tested and found effective in several production processes. This paper aims to propose a method of problem solving through the integration of the principles of lean thinking and the TPTOC （Thinking Process of the Theory of Constraints）. The method was implemented on a civil contractor, using the research methodology and the action research. We concluded that, after the research, the core problem regarding the company is the technical failure of the administrative staff, which causes delay in the construction works and financial loss. We also concluded that the obstacles that could prevent the achievement of objectives are related to lack of a vision from senior management regarding financial return when investing in employee training. The goal was accomplished with the integration of two philosophies, TPTOC and lean. And only the tools proposed by Fl^vio Augusto Picchi were not enough for executing the action, so new lean actions were verbalized.

关键词： Exchange information thinking process lean thinking