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Emission colour tuning in KLnF_(4):Yb^(3+),Er^(3+)/Ho^(3+)phosphor

Journal of Rare Earths 2024年第1期42卷 57-65,I0002页

作者： Janani K Gayathri E vijayatha.v.ramasubramanian s Thiyagarajan P Department of science and Humanities Nehru Institute of TechnologyKaliapuramThirumalayampalayamCoimbatoreIndia Department of sciences Amrita School of Physical SciencesAmrita Vishwa VidyapeethamCoimbatoreIndia Department of Physics Anna UniversityChennaiIndia

KLnF_(4):Yb^(3+),Er^(3+)/Ho^(3+)(Ln=Y,Yb,Gd)phosphors were prepared by solid-state reaction *** each of the Yb^(3+)/Er^(3+)and Yb^(3+)/Ho^(3+)co-doped phosphors independently,phase confirmation and morphological examination were accomplished using the X-ray diffraction technique and scanning electron microscope analysis.X-ray photoelectron spectroscopy analysis shows the charge state and existence of lanthanides and *** luminescence emissions of green and red colour were detected for the synthesized *** changes in the upconverted emission intensities and colour output pertaining to the change of the lanthanide host matrix along with dopants were investigated for the prepared *** the upconversion luminescence,erbium-doped samples exhibit a predominance of red emission while holmium-doped samples display a prevalence of green *** rare-earth Er/Ho doped KYbF4shows strong red emission compared to other ***_(4):Yb,Er/Ho exhibits relatively significant green upconve rsion emissions,while Yb,Er-doped KGdF_(4)host displays a 10-fold increase in green/red emission ratio with an increase in the input power of 20-780 *** photoluminescence studies and decay curve analysis were carried out using Uv light excitation for the developed phosphors.A higher lifetime of 2.2 ms was measured for the downshifting red emission in the Ho doped KYbF_(4)*** study suggests a potential for colour tunability in the upconversion and downshifting emissions through host modifications to the fluoride phosphor.

关键词： Rare earths Energy transfer upconversion Downshifting Colour coordinates

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Exosomal microRNAs from mesenchymal stem/stromal cells: Biology and applications in neuroprotection

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World Journal of stem Cells 2021年第7期13卷 776-794页

作者： Aida Nasirishargh Priyadarsini Kumar Lalithasri ramasubramanian Kaitlin Clark Dake Hao sabrina v Lazar Aijun Wang surgical Bioengineering Laboratory Department of SurgeryUniversity of CaliforniaDavis School of MedicineSacramentoCA 95817United States Institute for Pediatric Regenerative Medicine Shriners Hospitals for ChildrenSacramentoCA 95817United States Department of Biomedical Engineering University of California DavisDavisCA 95616United States

Mesenchymal stem/stromal cells(MsCs)are extensively studied as cell-therapy agents for neurological *** studies consider exosomes secreted by MsCs as important mediators for MsCs’neuroprotective *** transfer functional molecules including proteins,lipids,metabolites,DNAs,and coding and non-coding RNAs from MsCs to their target *** evidence shows that exosomal microRNAs(miRNAs)play a key role in the neuroprotective properties of these exosomes by targeting several genes and regulating various biological *** exosomal miRNAs have been identified to have neuroprotective effects by promoting neurogenesis,neurite remodeling and survival,and ***,exosomal miRNAs have significant therapeutic potential for neurological disorders such as stroke,traumatic brain injury,and neuroinflammatory or neurodegenerative diseases and *** review discusses the neuroprotective effects of selected miRNAs(miR-21,miR-17-92,miR-133,miR-138,miR-124,miR-30,miR146a,and miR-29b)and explores their mechanisms of action and applications for the treatment of various neurological disease and *** also provides an overview of state-of-the-art bioengineering approaches for isolating exosomes,optimizing their yield and manipulating the miRNA content of their cargo to improve their therapeutic potential.

关键词： Mesenchymal stromal cells Mesenchymal stromal cell-derived exosomes Exosomal microRNAs Neuroprotective effect

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