检索结果-南通市图书馆

Acta Pharmaceutica Sinica B 2024年第1期14卷 273-291页

作者： Duc-Vinh Pham Thi-Kem nguyen Bao-Loc nguyen Jong-Oh Kim Jee-Heon Jeong Inho Choi Pil-Hoon Park Department of Pharmacology Hanoi University of PharmacyHanoi 100000Viet Nam College of Pharmacy Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541Republic of Korea Research Institute of Cell Culture Yeungnam UniversityGyeongsan 38541Republic of Korea Department of Precision Medicine School of MedicineSungkyunkwan UniversitySuwon 16419Republic of Korea

Obesity has been known to negatively modulate the life-span and immunosuppressive potential of mesenchymal stromal cells(MSC).However,it remains unclear what drives the compromised potency of obese *** this study,we examined the involvement of adiponectin,an adipose tissuederived hormone,in obesity-induced impaired therapeutic function of ***-induced obesity leads to a decrease in serum adiponectin,accompanied by impairment of survival and immunomodulatory effects of adipose-derived MSC(ADSC).Interestingly,priming with globular adiponectin(gAcrp)improved the immunomodulatory potential of obese *** effects were also observed in lean *** addition,gAcrp potentiated the therapeutic effectiveness of ADSC in a mouse model of DSS-induced ***,while obesity inhibited the glycolytic capacity of MSC,gAcrp treatment induced a metabolic shift toward glycolysis through activation of adiponectin receptor type 1/p38 MAPK/hypoxia inducible factor-1a *** findings suggest that activation of adiponectin signaling is a promising strategy for enhancing the therapeutic efficacy of MSC against immune-mediated disorders.

关键词： Adiponectin Adipose-derived stromal cells Colitis Glycolytic induction HIF1a Immunomodulation Mesenchymal stromal cells Obesity

Effect of Freeze-Thaw and Urea in Solubility of GPC3-Csub Protein Expressed in Escherichia coli

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2024年第4期12卷 288-297页

作者： Xuan-Truc Chu-Dao Kim-Tuyen Huynh-Dam Dang-Thuc Ngo-Luong Quang-Luan Le thanh-Thao Vo-nguyen Department of Medical Biotechnology Biotechnology Center of Ho Chi Minh City Ho Chi Minh City Vietnam

Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential target molecule for liver cancer treatments because of its over-expression and growth effects on hepatocellular carcinoma (HCC). This study examined the expression and purification of a C-terminal subunit of Glypican-3 protein (GPC3-Csub) due to its application in both diagnosis and therapy for hepatocellular carcinoma. The gene encoding for GPC3-Csub was successfully cloned into plasmid pET28a fused with an affinity tag composed of six consecutive histidine residues (His-tag). Recombinant protein GPC3-Csub was expressed in Escherichia coli BL21 (DE3) in the condition of adding 3% ethanol with IPTG induction. GPC3-Csub was extracted using repeated freeze-thaw cycles with lysozyme, and inclusion bodies were solubilized by 8M Urea, SDS 10% in pH 12. His-tag fused GPC3-Csub proteins allowed it to be purified by affinity chromatography method using the Nickel-nitrilotriacetic acid (Ni-NTA) column. High expression of GPC3-Csub was confirmed by Coomassie staining and western-blot. GPC3-Csub could be isolated with a Ni-NTA column and have a purity of about 90%.

关键词： Glypican-3 Affinity Chromatography Inclusion Body Liver Cancer

New Results on H_(∞) Control for Nonlinear Conformable Fractional Order Systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2021年第1期34卷 140-156页

作者： MAI viet Thuan nguyen Thi Huyen Thu nguyen Huu Sau nguyen Thi thanh Huyen Department for Management of Science and Technology Development Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of Mathematics and Statistics Ton Duc Thang UniversityHo Chi Minh CityVietnam Faculty of General Science Hanoi University of Natural Resources and EnvironmentHanoiVietnam Faculty of Fundamental Science Hanoi University of IndustryHa NoiVietnam Department of Mathematics and Informatics Thainguyen University of SciencesThainguyenVietnam

This paper deals with H_(∞) control problem for nonlinear conformable fractional order systems. The authors first derive new sufficient condition for exponential stability of nonlinear conformable fractional order systems based on Lyapunov-like function method for conformable fractional order systems and linear matrix inequalities(LMIs) approach. Then, by introducing a new concepts of H_(∞) control problem for nonlinear conformable fractional order systems, the authors study H_(∞) performance analysis and H_(∞) state feedback controller design problems for the considered systems. In terms of LMIs, a sufficient condition is proposed to ensure the nonlinear conformable fractional order systems are not only exponentially stable, but also satisfy H_(∞) performance γ. An explicit expression for state feedback controllers is also designed to make the closed-loop system is exponentially stable with H_∞performance γ. Finally, numerical examples are given to illustrate the validity and effectiveness of the proposed results.

关键词： Conformable fractional-order H_(∞)control problems H_(∞)performance analysis linear matrix inequalities nonlinear systems

An Enhanced Ensemble-Based Long Short-Term Memory Approach for Traffic Volume Prediction

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第3期78卷 3585-3602页

作者： Duy Quang Tran Huy Q.Tran Minh Van nguyen Faculty of Civil Engineering Nha Trang UniversityNha Trang650000Vietnam Robotics and Mechatronics Research Group Faculty of Engineering and TechnologyNguyen Tat Thanh UniversityHo Chi Minh City700000Vietnam Department of Civil Engineering Ho Chi Minh City University of Technology and EducationHo Chi Minh City700000Vietnam

With the advancement of artificial intelligence,traffic forecasting is gaining more and more interest in optimizing route planning and enhancing service *** volume is an influential parameter for planning and operating traffic *** study proposed an improved ensemble-based deep learning method to solve traffic volume prediction problems.A set of optimal hyperparameters is also applied for the suggested approach to improve the performance of the learning *** fusion of these methodologies aims to harness ensemble empirical mode decomposition’s capacity to discern complex traffic patterns and long short-term memory’s proficiency in learning temporal ***,a dataset for automatic vehicle identification is obtained and utilized in the preprocessing stage of the ensemble empirical mode decomposition *** second aspect involves predicting traffic volume using the long short-term memory ***,the study employs a trial-and-error approach to select a set of optimal hyperparameters,including the lookback window,the number of neurons in the hidden layers,and the gradient descent ***,the fusion of the obtained results leads to a final traffic volume *** experimental results show that the proposed method outperforms other benchmarks regarding various evaluation measures,including mean absolute error,root mean squared error,mean absolute percentage error,and *** achieved R-squared value reaches an impressive 98%,while the other evaluation indices surpass the *** findings highlight the accuracy of traffic pattern ***,this offers promising prospects for enhancing transportation management systems and urban infrastructure planning.

关键词： Ensemble empirical mode decomposition traffic volume prediction long short-term memory optimal hyperparameters deep learning

越南北江农林大学中文专业 ——教学现状调查及发展策略研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

越南北江农林大学中文专业 ——教学现状调查及发展策略研究

作者：阮氏清水（nguyen THI thanh THUY）广西大学

学位级别：硕士

A Study on Optimizing the Double-Spine Type Flow Path Design for the Overhead Transportation System Using Tabu Search Algorithm

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Intelligent Automation & Soft Computing 2024年第2期39卷 255-279页

作者： nguyen Huu Loc Khuu Thuy Duy Truong Quoc Dien Le Tran thanh Cong Vu Hoa Binh Tran Tuong Quan Vo Department of Mechatronics Faculty of Mechanical EngineeringHo Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam Bach Khoa Research Center for Manufacturing Engineering Ho Chi Minh City University of Technology(HCMUT)Ho Chi Minh CityVietnam vietnamNational University Ho ChiMinh City Ho ChiMinh CityVietnam

Optimizing Flow Path Design(FPD)is a popular research area in transportation system design,but its application to Overhead Transportation Systems(OTSs)has been *** study focuses on optimizing a double-spine flow path design for OTSs with 10 stations by minimizing the total travel distance for both loaded and empty *** employ transportation methods,specifically the North-West Corner and Stepping-Stone methods,to determine empty vehicle travel ***,the Tabu Search(TS)algorithm is applied to branch the 10 stations into two main layout *** results obtained from our proposed method demonstrate a reduction in the objective function value compared to the initial feasible ***,we explore howchanges in the parameters of the TS algorithm affect the optimal *** validate the feasibility of our approach by comparing it with relevant literature and conducting additional tests on layouts with 20 and 30 stations.

关键词： Overhead transportation systems tabu search double-spine layout transportationmethod empty travel flow path design

Moving Least Squares Interpolation Based A-Posteriori Error Technique in Finite Element Elastic Analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2021年第10期129卷 167-189页

作者： Mohd Ahmed Devender Singh Saeed Al Qadhi nguyen viet thanh Civil Engineering Department College of EngineeringKing Khalid UniversityAbha61421Saudi Arabia Ministry of Information Soochna BhavanCGO ComplexDelhi110003India Urban Transport&Coastal Engineering Department University of Transport and CommunicationsHanoi100000Vietnam

The performance of a-posteriori error methodology based on moving least squares(MLS)interpolation is explored in this paper by varying the finite element error recovery parameters,namely recovery points and field variable derivatives *** MLS interpolation based recovery technique uses the weighted least squares method on top of the finite element method’s field variable derivatives solution to build a continuous field variable derivatives *** boundary of the node support(mesh free patch of influenced nodes within a determined distance)is taken as circular,i.e.,circular support domain constructed using radial weights is *** field variable derivatives(stress and strains)are recovered at two kinds of points in the support domain,i.e.,Gauss points(super-convergent stress locations)and nodal *** errors are computed as the difference between the stress from the finite element results and projected stress from the post-processed energy norm at both elemental and global *** benchmark numerical tests using quadrilateral and triangular meshes measure the finite element errors in strain and stress *** numerical examples showed the support domain-based recovery technique’s capabilities for effective and efficient error estimation in the finite element analysis of elastic *** MLS interpolation based recovery technique performs better for stress extraction at Gauss points with the quadrilateral discretization of the problem *** is also shown that the behavior of the MLS interpolation based a-posteriori error technique in stress extraction is comparable to classical Zienkiewicz-Zhu(ZZ)a-posteriori error technique.

关键词： Recovery points field variable derivatives effectivity error recovery support domain error convergence

Fuzzy Decision Model: Evaluating and Selecting Open Banking Business Partners

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第9期72卷 4557-4570页

作者： Ngo Quang Trung nguyen Van thanh nguyen viet Tinh Syed Tam Husain Faculty of Commerce Van Lang UniversityHo Chi Minh City70000Vietnam

The finance supply chain has always been a different supply chain compared to product supply chain being a service supply *** Banking(OB)is one of the most important milestones since the beginning of financial technology innovation and service supply *** these are activities provided by traditional banks,non-bank financial institutions also provide financial service with access to consumer banking,transactional and other financial data to develop financial applications and services tailored to their *** development of financial technology,“Open banking”,promotes financial services to begin this ***,evaluating and selecting open banking business partners from multiple perspectives for banks are ***,the authors in this research proposed a hybrid multicriteria decision-making model which includes a Spherical Fuzzy Analytical Hierarchy Process(SF-AHP)model and a Multi-Attributive Ideal-Real Comparative Analysis(MAIRCA)model with supports from seasoned domain *** contribution of this research is a proposition of a fuzzy decision model for evaluating and selecting open banking business *** model successfully determined a suitable open bank provider in order to assist decision makers decide objectively.

关键词： Open banking MCDM SF-AHP MAIRCA fuzzy theory

Optimization Agricultural Supply Chain:A Case Study of Fertilizer Supplier Selection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第8期72卷 4057-4068页

作者： nguyen Van thanh nguyen Thi Kim Lan Syed Tam Husain nguyen Hoang Hai nguyen viet Tinh Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam International Education Institute Van Lang UniversityHo Chi Minh CityVietnam

The 21st century is associated with the IndustrialRevolution 4.0 and the organic agriculture trend,making the utilization of high-quality fertilizers,abundant nutritional content,economical,and no affect to environment *** to the new concept,clean agricultural production and organic agricultural products are not allowed to excessively use synthetic chemicals such as chemical fertilizers,and plant protection drugs,but priority is to use manure,organic fertilizers,and natural mineral *** must meet the balanced nutritional requirements of crops,maintain,and improve the fertility of the ground,protect the surrounding ecosystem,and leave harmful effects in agricultural products,products with high quality,safe for users and high economic efficiency for *** achieve the above goal,the selection of a fertilizer supplier is an important decision,supporting the supply chain’s sustainable development,fertilizer supplier selection is a multicriteria decision making model,the decision maker must assess all qualitative and quantitative *** this paper,the author proposed an integer decision making model including Fuzzy Analytic Hierarchy Process(FAHP)and Complex Proportional Assessment of Alternatives(COPRAS)for fertilizer supplier *** weightings of the criteria are calculated by using FAHP,COPRAS is then applied for ranking some potential fertilizer *** efficiency of the proposed models is proved by a case study conducted in a farm located in the south of *** research is the first fertilizer supplier evaluation and se-lection model in vietnam by interviewing experts and reviewing the ***-search result is to provide a case study on evaluating supplier in agricultural supply chain utilizing the model proposed by the combination of FAHP and COPRAS models.

关键词： Fertilizer industry optimization model fuzzy theory agricultural supply chain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

生物质气化技术介绍

江苏锅炉 2024年第3期 41-48页

作者： thanh Phong Mai Dinh Quan nguyen 汪小雯(译) Ho Chi Minh City University of Technology MAI THANH PHONG 无锡华光环保能源集团股份有限公司江苏无锡214024

气化是通过间接燃烧的方式将固体和液体生物质转化为可燃气体的过程。作为一种替代传统燃烧的方法,气化技术能够在很大程度上降低粉尘和有害气体的排放。本文旨在从环境影响和技术增益两个维度,对这两种生物质热转化方式展开比较分析,... 详细信息

气化是通过间接燃烧的方式将固体和液体生物质转化为可燃气体的过程。作为一种替代传统燃烧的方法,气化技术能够在很大程度上降低粉尘和有害气体的排放。本文旨在从环境影响和技术增益两个维度,对这两种生物质热转化方式展开比较分析,旨在为读者提供一个基础的选择参考。气化过程可细分为气化剂的选择、非催化工艺、催化工艺以及等离子体辅助工艺等几个方面。本文还将介绍常见的气化设备类型一一气化器,并结合其工作原理,对气化技术的利弊进行简要探讨。

关键词：气化气化炉生物质间接燃烧直接燃烧合成气等离子体上升降气流交又气流搭桥焦油木炭氢气蒸汽二氧化碳烟气