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Impacts of radiation therapy on quality of life and pain relief in patients with bone metastases

World Journal of Orthopedics 2024年第9期15卷 841-849页

作者： Armin Hoveidaei Mehdi Karimi vida khalafi Patrick Fazeli Amir Human Hoveidaei Students’Scientific Research Center Exceptional Talents Development CenterTehran University of Medical SciencesTehran ***Iran Bogomolets National Medical University Kyiv 01601Ukraine Student Research Committee Jahrom University of Medical SciencesJahrom ***Iran Brown University ProvidenceRI 02912United States International Center for Limb Lengthening Rubin Institute for Advanced OrthopedicsSinai Hospital of BaltimoreBaltimoreMD 21215United States

Bone metastases(BM)are a common complication in advanced cancer patients,significantly contributing to morbidity and mortality due to their ability to cause pain,fractures,and spinal cord *** therapy(RT)is vital in managing these complications by targeting metastatic lesions to ease pain,improve mobility,and reduce the risk of skeletal-related events such as *** supports the effectiveness of RT in pain relief,showing its ability to provide significant palliation and lessen the need for opioid painkillers,thereby enhancing the overall quality of life(QoL)for patients with ***,optimizing RT outcomes involves considerations such as the choice of radiation technique,dose fractionation schedules,and the integration of supportive care measures to mitigate treatment-related side effects like fatigue and skin *** factors highlight the importance of personalized treatment planning tailored to individual patient needs and tumor *** mini-review aims to provide comprehensive insights into the multifaceted impacts of RT on pain management and QoL enhancement in BM patients,with implications for refining clinical practices and advancing patient care through the synthesis of findings from various studies.

关键词： Radiation therapy Radiotherapy Quality of life Pain relief Bone metastases Bone cancer

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Dynamic analysis of the composite laminated repaired perforated plates by using multi-patch IGA method

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Chinese Journal of Aeronautics 2021年第1期34卷 266-280页

作者： Jamshid FAZILATI Vahid khalafi Aeronautical Science and Technology Department Aerospace Research InstituteTehran 14657-74111Iran Aerospace Engineering Department Shahid Sattari Aeronautical University of Science and TechnologyTehranIran

The bonded repair techniques seem to be the most frequent procedures in the aviation *** achieved composite repaired perforated thin-walled plate is a complex geometry with high numerical analysis *** NURBS-based Isogeometric Analysis(IGA)proposes a sensible and affordable tool to carry out such geometry *** this context,a well-known technique is to divide the original geometry assembly into number of simple neighbors connected *** the present study the free vibration analysis of the perforated plates repaired on one side with an external bonded composite laminated patch is investigated.A multi-patch geometry modeling approach is implemented in line with the first order shear deformation theory of *** order to hold the geometry integrity and uniformity,all the degrees of freedom between adjacent geometry patches are completely tied through implementing a Nitsche *** show the effectiveness and accuracy of the developed formulation,some representative results are extracted and compared with those from *** effects of geometrical as well as material parameters including boundary condition,cutout shape,and repair layup on the dynamic response of the repaired perforated plates are then investigated.

关键词： Composite laminate Perforated plate Bonded repair Isogeometric analysis(IGA) Multi-patch model

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Target optimization for a 10-MeV E-beam neutron converter

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Nuclear Science and Techniques 2010年第2期21卷 69-71页

作者： TABBAKH Farshid khalafi Hossein Institute of Nuclear Science and Technology Irradiation and Application Research School Atomic Energy Organization of Iran Tehran Iran Institute of Nuclear Science and Technology Atomic Energy Organization of Iran Tehran *** Iran

Accelerator-based target design and optimization is an approach for neutron generation. The target plays an important role for a neutron source on an electron accelerator. For optimizing a neutron source using 10 MeV electron beams of Rhodotron-TT200, Pb, Ta, or W alloys with Be were calculated as photo-neutron converter. The neutron yield, flux and energy were simulated using the MCNPX code. The results indicate that a 10 MeV electron beam is capable of producing high-intensity neutron flux of 1013n·cm–2·s–1 with average energy of 0.8 MeV.

关键词：优化目标电子束中子源电子加速器中子通量平均能量生成方法中子产额

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Two-phase flow component fraction measurement using gamma-ray attenuation technique

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Nuclear Science and Techniques 2017年第6期28卷 196-202页

作者： Mohsen Sharifzadeh Hosein khalafi Hosein Afarideh Ehsanallah Noori Radiation Application Research School Nuclear Science and Technology Research Institute Department of Energy Engineering and Physics AmirKabir University of Technology Nuclear Science and Technology Research Institute Plasma Research School Nuclear Science and Technology Research Institute

Multiphase flow meters as the potential alternatives to separation and metering techniques have been in rapid development since 1980 *** its field operation,the instrument should be calibrated in a standard *** spite of the known medium and large scale facilities all over the world,we developed a laboratory scale instrument for component fraction *** has a two-phase flow homogenizer loop with the clamp-on potential of the meters to provide a regime independent *** is capable of delivering a complete homogenization by γ-ray *** an error of±5%in component fraction measurements,this instrument is appropriate for testing and calibrating other meters.

关键词： Component fraction measurement Homogenization MATLAB-Based algorithm Pencilbeam collimation Gamma-ray attenuation

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A Flexible Multichannel Digital Random Pulse Generator Based on FPGA

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World Journal of Nuclear Science and Technology 2013年第4期3卷 109-116页

作者： Mohammad Arkani Hossein khalafi Naser Vosoughi Department of Energy Engineering Sharif University of Technology Tehran Iran Physics Department Amir-Kabir University of Technology Tehran Iran Radiation Application Research School Nuclear Science & Technology Research Institute (NSRTI) Atomic Energy Organization of Iran (AEOI) Tehran Iran Radiation Application Research School Nuclear Science & Technology Research Institute (NSRTI) Atomic Energy Organization of Iran (AEOI) Tehran Iran

The present paper describes a multichannel digital random pulse generator implemented in a 65-nm FPGA device. The random time interval generation is based on inverse transformation method. The output pulse generation rate, pulse width and the probability distribution function (PDF) of each channel might be individually selected by the computer through a USB cable connection. Statistical properties of the output channels can be adjusted and recorded in a fully dynamic flexible manner. The Poisson and uniform PDFs were tested and implemented for up to eight different channels in experiment, however, the implementation of any arbitrary PDF is possible by programming capability of the device as well. Detailed experimental results are expressed in the manuscript. The proposed equipment makes it possible to verify the complicated multichannel detection systems without having the radioactive experimental tests. This is a low cost instrumentation due to the FPGA-based construction.

关键词： Field Programmable Gate Array (FPGA) Random Pulse Generator Probability Distribution Function

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S37-104 用对甲苯碘酰氯直接将羧酸制备酰胺

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中国医药工业杂志 2006年第12期37卷 858-858页

作者： khalafi-Nezhad A 杨玉雷（摘）张秀平（校）

用硅胶吸附的铵盐和三乙胺与羧酸以对甲苯磺酰氯为缩合剂，在试管中混和1min，室温反应制备伯、仲、叔及芳香酰胺，反应无需溶剂，操作简洁，28例收率70％～90％。

关键词：对甲苯磺酰氯酰胺制备羧酸室温反应硅胶吸附碘缩合剂

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