检索结果-南通市图书馆

Diagnostic endoscopic ultrasonography:Assessment of safety and prevention of complications

World Journal of Gastroenterology 2012年第34期18卷 4659-4676页

作者： Christian Jenssen Maria victoria Alvarez-Sánchez Bertrand Napoléon Siegbert Faiss Department of Internal Medicine Krankenhaus M rkisch-Oderland GmbHD15344 StrausbergGermany Department of Gastroenterology and Hepatology Hopital Privé Jean MermozF69008 LyonFrance Department of Gastroenterology and Hepatology Asklepios Klinik BarmbekD22291 HamburgGermany

Endoscopic ultrasonography (EUS) has gained wide acceptance as an important, minimally invasive diagnostic tool in gastroenterology, pulmonology, visceral surgery and oncology. This review focuses on data regarding risks and complications of non-interventional diagnostic EUS and EUS-guided fine-needle biopsy (EUS-FNB). Measures to improve the safety of EUS und EUS-FNB will be discussed. Due to the specific mechanical properties of echoendoscopes in EUS, there is a low but noteworthy risk of perforation. To minimize this risk, endoscopists should be familiar with the specific features of their equipment and their patients' specific anatomical situations (e.g., tumor stenosis, diverticula). Most diagnostic EUS complications occur during EUS-FNB. Pain, acute pancreatitis, infection and bleeding are the primary adverse effects, occurring in 1% to 2% ofpatients. Only a few cases of needle tract seeding and peritoneal dissemination have been reported. The mortality associated with EUS and EUS-FNB is 0.02%. The risks associated with EUS-FNB are affected by endoscopist experience and target lesion. EUS-FNB of cystic lesions is associated with an increased risk of infection and hemorrhage. Peri-interventional antibiotics are recommended to prevent cyst infection. Adequate education and training, as well consideration of contraindications, are essential to minimize the risks of EUS and EUS-FNB. Restricting EUS-FNB only to patients in whom the cytopathological results may be expected to change the course of management is the best way of reducing the number of complications.

关键词： Endoscopic ultrasonography Endoscopic ul-trasonography-guided fine-needle biopsy Complications Contraindications Risk Safety Perforation Bleeding Infection Acute pancreatitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antidiarrheal activity of hexane extract of Citrus limon peel in an experimental animal model

引用

Journal of Integrative Medicine 2017年第2期15卷 158-164页

作者： Olasupo Stephen Adeniyi James Omale Samuel Chukwuma Omeje victoria Ojimaojo Edino Department of Human Physiology Faculty of Basic Medical Sciences Kogi State University Anyigba 272102 Nigeria Department of Biochemistry Faculty of Natural Sciences Kogi State University Anyigba 272102 Nigeria

OBJECTIVE： Acute diarrhea is one of the major illnesses that cause death in children, despite clinical interventions and the use of oral rehydration therapy. Thus, there is need to discover other effective, affordable and accessible treatments for this disease. Therefore, this study was carried out to investigate the effects of hexane extract of Citrus limon peel （HECLP） on castor oil-induced diarrhea in rats. METHODS： Diarrhea was induced in male albino Wistar rats weighing 100-150 g. The antidiarrheal activity of HECLP at different oral dosages （5, 10 and 20 mg/kg） was investigated by counting the number of wet fecal pellets. Animals were further treated with propranolol, prazosin, nifedipine and atropine to assess the effects of receptor blockers on the activities of the extract. The effects of HECLP on castor oil-induced enteropooling and the intestinal transit time of activated charcoal were also evaluated. RESULTS： Each of the 3 doses of C. limon significantly reduced （P 〈 0.05） the number of wet fecal pellets produced by animals, with 20 mg/kg HECLP producing the highest percentage inhibition （34.2%） Wet fecal pellet inhibition by the standard drug Ioperamide （3 mg/kg p.o.） was 68.4% relative to the negative control. Blockage of 13 adrenergic receptors by propanolol abolished the antidiarrheal effects of HECLP. Intestinal fluid accumulation was inhibited by 68.7% and 78.5% by 20 mg/kg HECLP and Ioperamide respectively. Furthermore, 20 mg/kg HECLP significantly （P 〈 0.05） reduced the percentage intestinal transit time （21.4% ± 1.42%）, relative to the control （34.2% ±4.29%）; atropine （5 mg/kg, intraperitoneal injection） significantly （P 〈 0.001） reduced the percentage intestinal transit time to 11.2% ±0.85%. CONCLUSION： These results suggest that C. limon peel possesses antidiarrheal effects through antisecretory and antimotility mechanisms that act through the β adrenergic system.

关键词： antimotility antisecretory diarrhea lemon peel

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Generation of nanomaterials by reactive laser-synthesis in liquid

引用

Science China(Physics,Mechanics & Astronomy) 2022年第7期65卷 3-47页

作者： Laysa M.Frias Batista Ashish Nag victoria K.Meader Katharine Moore Tibbetts Department of Chemistry Virginia Commonwealth UniversityRichmond VA 23284USA

Nanomaterials with tailored structures and surface chemistry are in high demand, as these materials play increasingly important roles in biology, catalysis, energy storage, and manufacturing. Their heightened demand has attracted attention towards the development of synthesis routes, particularly, laser-synthesis techniques. These efforts drove the refinement of laser ablation in liquid(LAL) and related methods over the past two decades and have led to the emergence of reactive laser-synthesis techniques that exploit these methods’ characteristic, non-equilibrium conditions. Reactive laser-synthesis approaches foster unique chemical reactions that enable the formation of composite products like multimetallic nanoparticles, supported nanostructures, and complex minerals. This review will examine emerging reactive laser-synthesis methods in the context of established methods like *** focus will be on the chemical reactions initiated within the laser plasma, with the goal of understanding how these reactions lead to the formation of unique nanomaterials. We will provide the first systematic review of laser reaction in liquid(LRL) in the literature, and bring a focus to the chemical reaction mechanisms in LAL and reactive-LAL techniques that have not yet been emphasized in reviews. Discussion of the current challenges and future investigative opportunities into reactive laser-synthesis will impart guidance for researchers interested in designing reactive laser-synthesis approaches to novel nanomaterial production.

关键词： laser ablation in liquids laser reduction in liquids nanoparticles

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

《前哥伦布时期中国人的全球探索:一幅古世界地图的证据》书评

引用

青海师范大学学报（社会科学版） 2024年第2期46卷 160-164页

作者： [美]维多利亚·贝拉 [美]王胜炜(译) 《南华早报》中国香港美国南加州大学

学者王胜炜所著的《前哥伦布时期中国人的全球探索:一幅古世界地图的证据》(1)是一本有关中国历史的新书,书中指出,明朝的宝船队曾远航至美洲、澳洲,作者通过分析1602年出版的中文世界地图《坤舆万国全图》来主张她的观点。这篇书评分... 详细信息

学者王胜炜所著的《前哥伦布时期中国人的全球探索:一幅古世界地图的证据》(1)是一本有关中国历史的新书,书中指出,明朝的宝船队曾远航至美洲、澳洲,作者通过分析1602年出版的中文世界地图《坤舆万国全图》来主张她的观点。这篇书评分为两部分,在书评第一部分中,中国香港《南华早报》的科学作家维多利亚·贝拉(victoria Bela),考查了来自东方的古代水手先于哥伦布踏上美洲海岸的问题。

关键词：世界地图书评《坤舆万国全图》《南华早报》哥伦布维多利亚

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Phylogenetic endemism of the orchids of Megamexico reveals complementary areas for conservation

引用

Plant Diversity 2022年第4期44卷 351-359页

作者： Brandon E.Gutierrez-Rodríguez Marilyn Vasquez-Cruz victoria Sosa Instituto de Ecología AC Carretera Antigua a Coatepec 351El Haya91073 XalapaVeracruzMexico Unidad de Genomica Avanzada Laboratorio Nacional de Genomica para La BiodiversidadCentro de Investigaciony Estudios Avanzados IrapuatoLibramiento Norte Carretera Leon Km.9.636821 IrapuatoGuanajuatoMexico

Orchid diversity provides a unique opportunity to further our understanding of biotic and abiotic factors linked to patterns of richness,endemism,and phylogenetic endemism in many ***,orchid diversity is consistently threatened by illegal trade and habitat ***,we identified areas critical for orchid conservation in the biogeographic province of *** this purpose,we evaluated orchid endemism,phylogenetic diversity,and phylogenetic endemism within Megamexico and characterized orchid life *** results indicate that the majority of the regions with the highest estimates of endemism and phylogenetic endemism are in southern Mexico and northern Central America,mostly located on the Pacific side of *** the most important orchid lineages,several belong to epiphytic lineages such as Pleurothallidinae,Laeliinae and *** also found that species from diverse and distantly related lineages converge in montane forests where suitable substrates for epiphytes ***,the southernmost areas of phylogenetic diversity and endemism of Megamexico are in unprotected ***,we conclude that the most critical areas for orchid conservation in Megamexico are located in southern Mexico and northern Central *** recommend that these areas should be given priority by the Mexican system of natural protected areas as complementary conservation areas.

关键词： Epiphytes Geophytes Orchids Phylogenetic endemism Weighted endemism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Factors influencing syphilis treatment failure and/or re-infection in HIV co-infected patients： immunosuppression or behaviors

引用

Chinese Medical Journal 2011年第14期124卷 2123-2126页

作者： Jong Hun Kim George Psevdos Jr Jin Suh victoria Sharp Division of Infectious Diseases University of Pittsburgh Medical Center Pittsburgh PA USA Center for Comprehensive Care St. Luke's-Roosevelt Hospital Center New York USA

Background Recent studies have reported overall increasing rates of syphilis with a high rate of human immunodeficiency virus （HIV） co-infection. However, there is little information about factors influencing syphilis treatment failure and/or re-infection in HIV co-infected patients. We conducted a study to evaluate factors associated with syphilis treatment failure/re-infection in HIV co-infected *** We reviewed 3542 medical records of HIV-infected patients from January 2005 to December 2007 followed up at HIV Clinic in New York City. Patients were categorized by rapid plasma regain titer （RPR） into success/serofast （4-fold decrease in RPR by 12 months after treatment, RPR conversion to nonreactive, persistently stable reactive RPR with no 4-fold increase）, and failure/re-infection （failure to decrease 4 folds in RPR by 12 months after treatment, 4-fold increase in RPR from baseline）.Results Among a total of 156 patients who met the eligibility criteria, 122 （78.2％） were under success/serofast category,and 34 （21.8％） were under failure/re-infection category. HIV viral load, CD4 cell count, and use of highly active antiretroviral therapy （HAART） were not associated with syphilis treatment failure/re-infection. However, early syphilis stage （OR：11.036, 95％ CI： 2.499-48.740, P=0.002） and high （＞1∶64） RPR titers （OR： 715.921, 95％ CI： 422.175-23 113.396, P ＜0.001） were significantly *** No correlations were seen with depressed immune states with syphilis treatment failure and/or re-infection. However, association with early stage syphilis suggests that risky psychological sexual behaviors may be the most important leading factor, emphasizing needs for safe sex education.

关键词： human immunodeficiency virus syphilis treatment failure re-infection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microglia depletion as a therapeutic strategy:friend or foe in multiple sclerosis models?

引用

Neural Regeneration Research 2023年第2期18卷 267-272页

作者： victoria Sofia Berenice Wies Mancini Anabella Ayelen Di Pietro Laura Andrea Pasquini Universidad de Buenos Aires Facultad de Farmacia y BioquímicaDepartamento de Química BiológicaCátedra de Química Biológica PatológicaBuenos AiresArgentina Universidad de Buenos Aires Consejo Nacional de Investigaciones Científicas y TécnicasInstituto de Química y Fisicoquímica Biológicas Prof.Dr.Alejandro C.PaladiniFacultad de Farmacia y BioquímicaBuenos AiresArgentina

M ultiple sclerosis is a chro nic central nervous system demyelinating disease whose onset and progression are driven by a combination of immune dysregulation,genetic predisposition,and environmental fa *** activation of microglia and astrocytes is a key player in multiple sclerosis immunopathology,playing specific roles associated with anatomical location and phase of the disease and controlling demyelination and *** though reactive mic roglia can damage tissue and heighten deleterious effects and neurodegeneration,activated microglia also perform neuroprotective functions such as debris phagocytosis and growth fa ctor *** can be activated into pro-inflammato ry phenotype A1 through a mechanism mediated by activated neuroinflammatory microglia,which could also mediate *** A1 phenotype inhibits oligodendrocyte prolife ration and differe ntiation and is toxic to both oligodendrocytes and *** r,astroglial activation into phenotype A2 may also take place in response to neurodegeneration and as a protective mechanism.A variety of animal models mimicking specific multiple sclerosis features and the associated pathophysiological processes have helped establish the cascades of events that lead to the initiation,progression,and resolution of the *** colonystimulating facto r-1 receptor is expressed by myeloid lineage cells such as peripheral monocytes and macrophages and central nervous system ***,as microglia development and survival critically rely on colony-stimulating factor-1 receptor signaling,colony-stimulating factor-1 receptor inhibition can almost completely eliminate microglia from the *** this context,the present review discusses the impact of microglial depletion through colo ny-stimulating factor-1 receptor inhibition on demyelination,neurodegeneration,astroglial activation,and behavior in different multiple sclerosis models,highlighting the diversity of micr

关键词： astrocytes colony-stimulating factor-1 receptor inhibition cuprizone demyelnation microglia multiple sclerosis neurodegeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A good gut feeling on Sarm1-mediated axon degeneration

引用

Protein & Cell 2021年第8期12卷 596-598页

作者： victoria E.von Saucken David J.Simon Department of Biochemistry Weill Cornell Medical College Tri-Institutional MD-Ph D Program Weill Cornell Medicine Rockefeller University Memorial Sloan Kettering Cancer Center

Axons,the cable-l ike projections of neurons,experience a wide range of stressors throughout their *** result of any one of these challenges can be catastrophic,promoting degeneration of the *** degeneration is an active signaling process observed in traumatic brain injury,chemotherapy-induced peripheral neuropathies,and neurodegen erative disease (Simon and Watkins,2018;Coleman and Hoeke,2020).As a result,tremendous efforts have been made to identify biological targets that can be harnessed to block axon degeneration to treat these *** promising candidate is Sarm1 (sterile alpha and TIR motif containing protein 1),a member of the Myd88 immune adaptor protein family that itself has no clear role in innate immunity.

关键词： SARM1 ACTIVATION TRIGGERS DEATH

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

E-Commerce and Market Expansion:A Case Study on Zimbabwe Safari Tourism

E-Commerce and Market Expansion:A Case Study on Zimbabwe Saf...

引用

作者： Gono Vimbai victoria 浙江科技学院

学位级别：硕士

E-commerce is considered as one of the most important innovations in modern day's businesses as it has provided a lot of ease to not only producers to advertise their products but also for consumers to get a vast awareness about any product or service *** tourism industry has transpired as the largest contributor of the GDP in most African countries and that includes Zimbabwe,and is now regarded as the only hope for turning around African *** studies all points to a positive expansion of the tourism industry and governments have established organizations responsible for developing both domestic and international *** tourism regulator bodies are now engaging in dual marketing strategies which involve both the traditional marketing and the current technology based marketing strategies which include the use of the *** Safaris have emerged as an astonishing tourist spot in the last few years,but in spite of a lot of fascinations,still the required levels of tourists are not *** study has aimed to investigate the impact of Internet marketing and its effectiveness towards the Zimbabwe Safari tourism sector.A structured questionnaire was filled by 200 respondents and the results were analyzed on *** results have demonstrated that Internet Marketing plays a significant positive role in the effectiveness of Zimbabwean *** study has its inferences for academia,practical field and policy *** and future research indications have also been added in the study.

关键词： Internet Marketing Safari Tourism Effectiveness Zimbabwean Safaris

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Gender Media Representation in Uruguay：An Analysis of TV Ciudad，El País，and Del Sol FM.

Gender Media Representation in Uruguay：An Analysis of TV Ci...

引用

作者： Maria victoria Techera 中国传媒大学

学位级别：硕士

这项研究探讨乌拉圭媒体中的性别表现,具体聚焦于电视台Ciudad、报纸El País和广播Del Sol FM,分别代表该国的三大主要媒体,并涵盖其三个政治派别.通过采用内容分析、调查和访谈等混合方法,本研究调查了影响乌拉圭媒体性别表现的因素... 详细信息

这项研究探讨乌拉圭媒体中的性别表现,具体聚焦于电视台Ciudad、报纸El País和广播Del Sol FM,分别代表该国的三大主要媒体,并涵盖其三个政治派别.通过采用内容分析、调查和访谈等混合方法,本研究调查了影响乌拉圭媒体性别表现的因素、女性在媒体内容创作中的角色以及三个媒体机构之间的性别表现差异.本文运用内容分析方法分析了一部分新闻文章、电视节目和广播节目,旨在识别普遍存在的性别刻板印象、女性在领导岗位上的存在程度以及对女性在传统性别角色中的描绘.研究结果显示,在媒体中,女性经常被低估和边缘化,男性更有可能担任领导职位并获得新闻报道.此外,女性往往被描绘成传统的性别角色。研究还强调了媒体素养教育的重要性,作为使个人能够批判性地分析和评估媒体表现的手段,使他们能够识别和挑战媒体内容中的性别刻板印象和偏见.这些发现突显了乌拉圭媒体行业迫切需要加强性别平等和多样性的需求。解决这种差距的潜在策略包括设定女性在领导职位中的代表目标,促进多元化和赋权的女性形象在媒体内容中的呈现,以及解决媒体机构内的性别薪酬差距.通过采取这些措施,旨在为乌拉圭和其他地区创造一个更具包容性和公平性的媒体行业.

关键词： GenderMedia representation Uruguay Media Literacy Critical Media

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：