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Advances in Enzyme Research 2016年第3期4卷 98-112页

作者： Lluvia Sánchez-Pérez Silvia Rodríguez-navarro victor hugo marín-cruz Miguel Ángel Ramos-López Alejandro Palma Ramos Juan Esteban Barranco-Florido Masters Program in Agricultural Sciences Division of Biological and Health Metropolitan Autonomous University-Xochimilco Coyoacán México Departament of Agricultural and Animal Production Metropolitan Autonomous University-Xochimilco Coyoacán México Faculty of Chemistry Autonomous University of Queretaro Santiago de Querétaro México Department of Biological Systems Metropolitan Autonomous University-Xochimilco Coyoacán México

The application of enzymatic extracts and conidia of Beauveria bassiana in Metamasius spinolae and Cyclocephala lunulata was evaluated. The variables were mortality and time of death. In M. spinolae, mortality with extracts 29%, conidia 27% and the combination of both 31%, all had a time of death of four days. Although with different symptoms, used enzymatic extracts: contraction and softening of the joints;by conidia: mycelium in the joints;in the combination of conidia and enzymatic extracts: abundant aerial mycelium. In C. lunulata, 100% mortality in all treatments;Time of death: enzymatic extracts and extracts with conidia 1.2 days;conidia 2.8 days. Symptoms were different, enzymatic extracts: melanization and internal tissue lysis;enzymatic extract and conidia: mycelium emerged and melanization;conidia: mycelium emerged. Enzymatic extracts showed insecticidal activity in M. spinolae and C. lunulata. These results suggest the potential of enzymatic extracts as biocontrol agents to improve the use of entomopathogenic fungi.

关键词： Insecticidal Activity Beauveria bassiana Metamasius spinolae Cyclocephala lunulata Enzymatic Extracts

Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

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neural Regeneration Research 2025年第4期20卷 1079-1080页

作者： victor V.Chizhikov Igor Y.Iskusnykh Department of Anatomy and neurobiology University of Tennessee Health Science CenterMemphisTNUSA

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical *** such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in *** cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)*** cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

关键词： epithelium Figure center

Interactive association between processing induced molecular structure changes and nutrient delivery on a molecular basis,revealed by cutting-edge vibrational biomolecular spectroscopy

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Journal of Animal Science and Biotechnology 2020年第1期11卷 211-226页

作者： Aya Ismael victor hugo Guevara-Oquendo Basim Refat Peiqiang Yu Ministry of Agriculture Strategic Research Chair(PY)Lab Department of Animal and Poultry ScienceCollege of Agriculture and BioresourcesUniversity of Saskatchewan51 Campus DriveSaskatoonSK S7N 5A8Canada

Background:This study was conducted to determine protein molecular structure profiles and quantify the relationship between protein structural features and protein metabolism and bioavailability of blend pel eted products(BPP)based on co-products(canola or carinata)from processing with different proportions of pulse pea screenings and lignosulfonate chemical ***:The protein molecular structures were determined using the non-invasive advanced vibrational molecular spectroscopy(ATR-FT/IR)in terms of chemical structure and biofunctional groups of amides(ⅠandⅡ),α-helix andβ-***:The results showed that increasing the level of the co-products in BPP significantly increased the spectral intensity of the amide area and amide *** products exhibited similar protein secondaryα-helix toβ-sheet *** protein molecular structure profiles(amidesⅠandⅡ,α-helix toβ-sheet)were highly associated with protein degradation kinetics and intestinal *** conclusion,the non-invasive vibrational molecular spectroscopy(ATR-FT/IR)could be used to detect inherent structural make-up characteristics in ***:The molecular structural features related to protein biopolymer were highly associated with protein utilization and metabolism.

关键词： Alpha-helix and beta-sheet Amides(ⅠandⅡ) Biofunctional groups Chemical structure Protein metabolism and bioavailability Protein molecular structure

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-Mañé Laia Just-Borràs marta Balanyà-Segura Aleksandra Polishchuk Laura nadal marta Tomàs Carolina Silvera-Simón Manel M.Santafé maria A.Lanuza Unitat d’Histologia i neurobiologia(UHneurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75nTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the n-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB

Glacial reconstruction and periglacial dynamics at the end of Late Pleistocene on the surface of Cofre de Perote volcano,México:a climatological retrospective

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Journal of Mountain Science 2023年第9期20卷 2453-2467页

作者： victor SOTO hugo DELGADO-GRAnADOS Carlos M.WELSH Kenji YOSHIKAWA Centro de Ciencias de la Tierra Universidad VeracruzanaXalapaVeracruz 91090México Instituto de Geofísica Universidad Nacional Autónoma de MéxicoCiudad de México 04150México Water and Environmental Research Center University of Alaska FairbanksFairbanksAlaska 99775USA

Despite being within the intertropical region of the planet,the Mexican territory still has glacier-covered *** recent decades,important advances have been made in studies on glaciology and periglacial environment in Mexico both for current and past ***,in spite of Cofre de Perote volcano(4200 m a.s.l.)being a strategically located mountain,it has not yet been studied in regards to the glacial and periglacial processes;in fact,those dynamics have modified the mountain massifs in the *** complement the series of studies on glacial history in the high mountain environment of México,this study reconstructs the glacial cover and the periglacial environment of the volcano surface during the final stage of the Late Pleistocene based on climatic retrospective and through the identification of geomorphological *** findings indicate the existence of a large glacier(ice cap)that covered the northern,western,and southern slopes of the mountain;while in the eastern sector there were two small glaciers,one being of cirque type,and the other of valley *** current temperature conditions prevent the occurrence of permanent ice bodies;at the same time,it was found that the periglacial blockfields of the slopes is a legacy of the climatic conditions that prevailed at the end of Late Pleistocene.

关键词： Cofre de Perote Glacial cover Periglacial environment Climatic retrospective Palaeoclimatic modelling

Ecological succession of benthic organisms on niche-type artificial reefs

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