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Target Capturing in an Ellipsoidal Region for a Swarm of Double Integrator Agents

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IEEE/CAA Journal of Automatica Sinica 2022年第5期9卷 801-811页

作者： Antonio Bono Luigi D'Alfonso Giuseppe Fedele veysel Gazi IEEE Department of Informatics ModelingElectronics and Systems EngineeringUniversity of CalabriaRende 87036Italy Dept.Electrical and Electronics Eng. Faculty of EngineeringMarmara UniversityIstanbul 34722 Department of Control and Automation Engineering Faculty of Electrical and Electronics EngineeringYildiz Technical UniversityEsenler 34220Turkey

In this paper we focus on the target capturing problem for a swarm of agents modelled as double integrators in any finite space *** agent knows the relative position of the target and has only an estimation of its velocity and *** that the estimation errors are bounded by some known values,it is possible to design a control law that ensures that agents enter a user-defined ellipsoidal ring around the moving *** know the relative position of the other members whose distance is smaller than a common detection ***,in the case of no uncertainty about target data and homogeneous agents,we show how the swarm can reach a static configuration around the moving *** simulations are reported to show the effectiveness of the proposed strategy.

关键词： Agents-based systems cooperative control swarms target-capturing

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Sentinel-1 In SAR observations and time-series analysis of co-and postseismic deformation mechanisms of the 2021 Mw 5.8 Bandar Ganaveh Earthquake,Southern Iran

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Journal of Mountain Science 2023年第4期20卷 911-927页

作者： Reza SABER veysel ISIK Ayse CAGLAYAN Marjan TOURANI Department of Geological Engineering Tectonics Research GroupAnkara UniversityTR-06830AnkaraTürkiye Department of Geological Survey Ministry of Environment and UrbanisationGeneral Directorate of Spatial PlanningTR-06520AnkaraTürkiye

In the past two decades,because of the significant increase in the availability of differential interferometry from synthetic aperture radar and GPS data,spaceborne geodesy has been widely employed to determine the co-seismic displacement field of *** April 18,2021,a moderate earthquake(Mw 5.8)occurred east of Bandar Ganaveh,southern Iran,followed by intensive seismic activity and aftershocks of various *** use two-pass D-InSAR and Small Baseline Inversion techniques via the LiCSBAS suite to study the coseismic displacement and monitor the four-month post-seismic deformation of the Bandar Ganaveh earthquake,as well as constrain the fault geometry of the co-seismic faulting mechanism during the seismic *** show that the co-and postseismic deformation are distributed in relatively shallow depths along with an NW-SE striking and NE dipping complex reverse/thrust fault branches of the Zagros Mountain Front Fault,complying with the main trend of the Zagros *** average cumulative displacements were obtained from-137.5 to+113.3 mm/yr in the SW and NE blocks of the Mountain Front Fault,*** received maximum uplift amount is approximately consistent with the overall orogen-normal shortening component of the Arabian-Eurasian convergence in the Zagros *** surface ruptures were associated with the seismic source;therefore,we propose a shallow blind thrust/reverse fault(depth~10 km)connected to the deeper basal decollement fault within a complex tectonic zone,emphasizing the thin-skinned tectonics.

关键词： Sentinel‑1 InSAR time-series Neotectonic reactivation Seismogenic fault Bandar Ganaveh earthquakes Zagros Fold-Thrust Belt Arabian-Eurasian collision

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Scour and liquefaction issues for anchors and other subsea structures in floating offshore wind farms: A review

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Water Science and Engineering 2022年第1期15卷 3-14页

作者： B.Mutlu Sumer veysel Sadan Ozgur Kirca BM SUMER Consultancy&Research ITU ARI Teknokent 1Nol5Istanbul 34467Turkey Department of Civil Engineering Istanbul Technical UniversityMaslak 34467Turkey

This article reviews scouring and liquefaction issues for anchor foundations of floating offshore wind *** review is organized in two sections:(1)the scouring issues for drag-embedment anchors(DEAs)and other subsea structures associated with DEAs such as tensioners,clump weights,and chains in floating offshore wind farms;and(2)the liquefaction issues for the same types of structures,particularly for *** scouring processes are described in detail,and the formulae and design guidelines for engineering predictions are included for quantities like scour depth,time scale,and sinking due to general shear failure of the bed soil caused by scoui\The latter is furnished with numerical ***,in the second section,the liquefaction processes are described with special reference to residual liquefaction where pore-water pressure builds up in undrained soils(such as fine sand and silt)under waves,leading to liquefaction of the bed soil and precipitating failure of DEAs and their associated subsea *** integrated mathematical model to deal with liquefaction around and the resulted sinking failure of DEAs,introduced in a recent study,has been *** of the model is illustrated with a numerical *** is believed that the present review and the existing literatures from the"neighboring"fields form a complementary source of information on scour and liquefaction around foundations of floating offshore wind farms.

关键词： Floating structures Liquefaction Offshore structures Offshore wind energy Renewable energy Scouring

Secondary causes of inflammatory bowel diseases

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World Journal of Gastroenterology 2020年第28期26卷 3998-4017页

作者： Yezaz A Ghouri veysel Tahan Bo Shen Department of Internal Medicine Division of Gastroenterology and HepatologyUniversity of Missouri-School of MedicineColumbiaMO 65201United States Department of Medicine and Surgery Interventional IBD CenterColumbia University Irving Medical Center/New York Presbyterian HospitalNew YorkNY 10032United States

Inflammatory bowel diseases(IBD),conventionally consist of Crohn’s disease(CD)and ulcerative *** occur in individuals with high risk genotype for the disease in the setting of appropriate environmental *** pathogenesis of IBD involves a dysregulated autoimmune response to gut dysbiosis,which in turn is triggered due to exposure to various inciting environmental *** there is no clearly defined etiology of IBD and this type of disease is termed as“idiopathic IBD”,“classic IBD”,or“primary IBD”.We reviewed the current medical literature and found that certain etiological factors may be responsible for the development of IBD or IBD-like conditions,and we consider this form of de novo IBD as“secondary IBD”.Currently known factors that are potentially responsible for giving rise to secondary IBD are medications;bowel altering surgeries and transplantation of organs,stem cells or fecal *** associated with the development of secondary IBD include;immunomodulators,anti-tumor necrosis factor alpha agents,anti-interleukin agents,interferons,immune stimulating agents and checkpoint *** can in some cases give rise to de novo CD,pouchitis of the ileal pouch,or postcolectomy enteritis *** solid organ transplantation or hematopoietic stem cell transplantation,the recipient may develop de novo IBD or IBD *** microbiota transplantation has been widely used to treat patients suffering from recurrent Clostridium difficile infection but can also causes IBD flares.

关键词： De novo inflammatory bowel disease Secondary inflammatory bowel disease Inflammatory bowel disease Crohn’s disease Ulcerative colitis

Immune checkpoint inhibitors induced colitis, stay vigilant: A case report

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World Journal of Gastrointestinal Oncology 2020年第6期12卷 699-704页

作者： Suha Abu Khalaf Abdulmajeed Albarrak Mohamad Yousef veysel Tahan Department of Internal Medicine University of MissouriColumbiaMO 65212United States Department of Internal Medicine College of MedicineQassim UniversityBuraydah 81999Saudi Arabia Division of Gastroenterology and Hepatology University of MissouriColumbiaMO 65212United States

BACKGROUND Colitis is one of the immune-related side effects of ***,such type of side effect was reported to develop within a few weeks of treatment initiation,our case started within a few *** SUMMARY We present a case of a 37-year-old gentleman with bright red loose stools,abdominal pain,and tenesmus.A diagnosis of colitis was made based on endoscopic and histologic *** was thereafter continued with oral steroids and discontinuation of the immunotherapy *** resolved after starting the treatment and the patient continued to be symptomfree on subsequent *** unique about this case report is that the patient developed bloody diarrhea within five days of the 1st immunotherapy cycle,and the patient was on combined ipilimumab and *** Immunotherapy related complications might occur within days from being on immunotherapy;we need more research to open the way for future pathological and clinical research to further understand the pathophysiology behind it.

关键词： Immunotherapy Colitis Melanoma Case report Ipilimumab Hepatitis

Influence of surface roughness of dune bedforms on flow and turbulence characteristics

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International Journal of Sediment Research 2020年第6期35卷 666-678页

作者： veysel Sadan Ozgur Kirca Seyed Mahdi Saghebian Kiyoumars Roushangar Oral Yagci Istanbul Technical University Department of Civil Engineering Department of Civil Engineering Ahar Branch Islamic Azad University Division of Hydraulics Department of Civil EngineeringUniversity of Tabriz

The current paper investigates the flow and turbulence characteristics over dune bedforms by means of laboratory experiments,where spatially dense and temporally high frequency velocity measurements were *** similar studies are available in the literature,the focus and novelty of the current study is to assess the influence of surface roughness of the dune bedforms on the nearbed *** direct comparison,two different surface roughness heights over idealized,fixed-shaped,high-angled dune bedforms were tested;one with a hydraulically-smooth surface,and the other with a fully-rough *** variation of time-averaged flow as well as turbulence statistics were examined,which was complemented by streamline plots and spectral *** results are interpreted from sediment entrainment and sediment transport points of *** results show that increased dune surface roughness reduces the nearbed flow velocity,but increases the flow velocities at upper *** upward directed flow near the dune crests becomes stronger in the case of smooth surface,while the reattachment point moves further downstream compared to the rough wall *** is concluded that the roughness of the dune surface affects the nearbed flow and turbulence characteristics qualitatively and quantitatively,which is shown to have direct consequences on sediment entrainment characteristics.

关键词： Bedforms Dunes Friction drag Turbulence Grain roughness Form drag

N-acetylcysteine attenuates alcohol-induced oxidative stress in the rat

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World Journal of Gastroenterology 2003年第1期9卷 125-128页

作者： Resat Ozaras veysel Tahan Seval Aydin Hafize Uzun Safiye Kaya Hakan Senturk Department of Infectious Diseases and Clinical Microbiology University of IstanbulIstanbulTurkey Department of Internal Medicine University of IstanbulIstanbulTurkey Department of Biochemistry University of IstanbulIstanbulTurkey

AIM: There is increasing evidence that alcohol-induced liverdamage may be associated with increased oxidative *** aimed to investigate free-radical scavenger effect of n-acetylcysteine in rats intragastrically fed with ***: Twenty-four rats divided into three groups werefed with ethanol (6 g/kg/day, Group 1), ethanol and n-acetylcysteine (1 g/kg, Group 2), or isocaloric dextrose(control group, Group 3) for 4 weeks. Then animals weresacrificed under ether anesthesia, intracardiac blood andliver tissues were obtained. Measurements were performedboth in serum and in homogenized liver *** (MDA) level was measured by TBARSmethod. Glutathione peroxidase (GSH-Px) and superoxidedismutase (SOD) levels were studied by commercial ***-Wallis test was used for statistical ***: ALT and AST in Group 1 (154 U/Land 302 U/L,respectively) were higher than those in Group 2 (94 U/L and155 U/L) and Group 3 (99 U/L and 168 U/L) (P＝0.001 forboth). Serum and tissue levels of MDA in Group 1 (1.84 nmol/mL and 96 nmol/100 mg-protein) were higher than Group 2(0.91 nmol/mL and 64 nmol/100 mg-protein) and Group 3(0.94 nmol/mL and 49 nmol/100 mg-protein) (P＜0.001 forboth). On the other hand, serum GSH-Px level in Group 1(8.21 U/g-Hb) was lower than Group 2 (16 U/g-Hb) andGroup 3 (16 U/g-Hb) (P＜0.001). Serum and liver tissue levelsof SOD in Group 1 (11 U/mL and 26 U/100 mg-protein)were lower than Group 2 (18 U/mL and 60 U/100 mg-protein)and Group 3 (20 U/mL and 60 U/100 mg-protein) (P＜0.001for both).CONCLUSION: This study demonstrated that ethanol-induced liver damage is associated with oxidative stress,and co-administration of n-acetylcysteine attenuates thisdamage effectively in rat model.

关键词： Oxidative Stress Acetylcysteine Animals Erythrocytes Ethanol dosage Free Radical Scavengers Glutathione Glutathione Peroxidase Lipid Peroxidation Liver Male Rats Rats, Wistar Research Support, Non-U.S. Gov't Superoxide Dismutase Thiobarbituric Acid Reactive Substances

N-acetylcysteine attenuates alcohol-induced oxidative stess in rats

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World Journal of Gastroenterology 2003年第4期9卷 791-794页

AIM:To investigate free-radical scavenger effect of n- acetylcysteine in rats intragastrically fed with ethanol. METHODS:Twenty-four rats divided into three groups were fed with ethanol (6 g/kg/day,Group 1),ethanol and n- acetylcysteine (1 g/kg,Group 2),or isocaloric dextrose (control group,Group 3) for 4 *** animals were sacrificed under ether anesthesia,and intracardiac blood and liver tissues were *** were made in both serum and homogenized liver tissues. Malondialdehyde (MDA) level was measured by TBARS *** peroxidase (GSH-Px) and superoxide dismutase (SOD) levels were studied by commercial kits. Kruskal-Wallis test was used for statistical analysis. RESULTS:ALT and AST in Group 1 (154 U/L and 302 U/L, respectively) were higher than those in Group 2 (94 U/L and 155 U/L) and Group 3 (99 U/L and 168 U/L) (P=0.001 for both).Serum and tissue levels of MDA in Group 1 (1.84 nmol/mL and 96 nmol/100 mg-protein) were higher than that in Group 2 (0.91 nmol/mL and 64 nmol/100 mg protein) and Group 3 (0.94 nmol/ml and 49 nmol/100 mg-protein) (P<0.001 for both).On the other hand,serum GSH-Px level in Group 1 (8.21 U/g Hb) was lower than that in Group 2 (16 U/g Hb) and Group 3 (16 U/g-Hb) (P<0.001).Serum and liver tissue levels of SOD in Group 1 (11 U/mL and 26 U/100 rag-protein) were lower than that in Group 2 (18 U/ mL and 60 U/100 mg protein) and Group 3 (20 U/mL and 60 U/100 rag-protein) (P<0.001 for both). CONCLUSION:Ethanol-induced liver damage was associated with oxidative stress,and co-administration of n-acetylolsteine attenuates this damage effectively in rat model.

关键词： Acetylcysteine Alanine Transaminase Animals Aspartate Aminotransferases Ethanol inhibitors Glutathione Glutathione Peroxidase Liver Male Malondialdehyde Oxidative Stress Rats Rats, Wistar Research Support, Non-U.S. Gov't Superoxide Dismutase

Dissecting the effects of androgen deprivation therapy on cadherin switching in advanced prostate cancer: A molecular perspective

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Oncology Research 2022年第3期30卷 137-155页

作者： LOKMAN VARISLI veysel TOLAN JIYAN H.CEN SPIROS VLAHOPOULOS OSMAN CEN Department of Molecular Biology and Genetics Science FacultyDicle UniversityDiyarbakir21280Turkey Cancer Research Center Dicle UniversityDiyarbakir21280Turkey Department of Chemical and Biomolecular Engineering University of IllinoisUrbanaIL61801USA First Department of Pediatrics National and Kapodistrian University of AthensAthens11527Greece Department of Microbiology and Immunology Feinberg School of MedicineNorthwestern UniversityChicagoIL60611USA Department of Natural Sciences and Engineering John Wood CollegeQuincyIL62305USA

Prostate cancer is one of the most often diagnosed malignancies in males and its prevalence is rising in both developed and developing *** deprivation therapy has been used as a standard treatment approach for advanced prostate cancer for more than 80 *** primary aim of androgen deprivation therapy is to decrease circulatory androgen and block androgen *** a partly remediation is accomplished at the beginning of treatment,some cell populations become refractory to androgen deprivation therapy and continue to *** evidences suggest that androgen deprivation therapy may cause cadherin switching,from E-cadherin to N-cadherin,which is the hallmark of epithelial-mesenchymal *** direct and indirect mechanisms are involved in this switching and consequently,the cadherin pool changes from E-cadherin to N-cadherin in the epithelial *** E-cadherin represses invasive and migrative behaviors of the tumor cells,the loss of E-cadherin disrupts epithelial tissue structure leading to the release of tumor cells into surrounding tissues and *** this study,we review the androgen deprivation therapy-dependent cadherin switching in advanced prostate cancer with emphasis on its molecular basis especially the transcriptional factors regulated through TFG-βpathway.

关键词： Prostate cancer Androgen signaling Androgen deprivation therapy Cadherin switching