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A catalyst-free new polyol method synthesized hot-pressed Cu-doped Bi2S3 nanorods and their thermoelectric properties

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Nano Research 2016年第11期9卷 3291-3304页

作者： Tarachand Vikash Sharma Ranu bhatt Vedachalaiyer Ganesan Gunadhor singh Okram UGC-DAE Consortium for Scientific Research Indore 452001 India Technical Physics Division Bhabha Atomic Research Centre Mumbai 400085 India

This is the first report on the thermoelectric properties of a catalyst-free polyol method used to prepare stoichiometric Bi2-xCuxS3 samples, x = 0.1, 0.2, 0.3, 0.4, via hot pressing. Various systematic approaches to arrive at in their stoichiometric compositions are explored precisely with introduction of excess precursor of S. X-ray diffraction data analysis using Rietveld refinement confirms a polyhedral orthorhombic crystal structure with a space group Pnma, in contrast to Pbnm reported earlier. Raman data further substantiates this. X-ray photoelectron spectroscopy confirms the valence states of the constituent elements （Bi^3＋, Cu^2＋, and S^2-） and energy dispersive X-ray analysis corroborates their compositions. The particle sizes of the pure Bi2S3 nanoparticles were 20, 35, and 82 nm as determined from the Scherrer formula, atomic force microscopy, and dynamic light scattering, respectively. Their transmission electron microscopy image shows rod-like nanostructures elongated in the 〈010〉 direction with an average diameter of 23 nm and a length of several hundreds of nanometers. A 34% improvement in the thermoelectric figure of merit is observed for Bi.6Cu0.4S3 as compared to pure Bi2S3 at 300 K.

关键词： Bi2S3 polyol nanorods thermoelectrics

vegetative propagation of Dalbergia sissoo:effect of growth regulators,length,position of shoot and type of cuttings on rooting potential in stem cuttings

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Forestry Studies in China 2012年第3期14卷 187-192页

作者： Bhupendra singh Rajendra YADAV B.P. bhatt Department of Forestry H.N.B.Garhwal UniversitySrinagar (Garhwal)Uttarakhand 246174India Chhattisgarh Minor Forest Produce Federation A-25VIP EstateKhamhardihShankar NagarRaipur 492007India ICAR Research Complex for Eastern Region PatnaBihar 800014India

The effect of auxins （IAA or IBA at 100, 200, 500 mg.L J） on rooting and sprouting parameters differed significantly （p 〈 0.05）. Rooting and sprouting percentages were higher in some treatments while other parameters were significantly higher in other treatments. The results of the present study revealed that rooting was significantly （p 〈 0.05） affected by the length of cuttings, as well as the position of shoots and type of cuttings. On average, 86.0 per cent rooting was observed in the 30-cm long cuttings com- pared to the other two lengths of cuttings, i.e., 20 and 25 cm, irrespective of any auxin treatment. In a control set, without any auxin treatment, a maximum of 60.0% rooting was recorded in the 30-cm long cuttings and a minimum of 40.0% of the cuttings rooted in the 20-cm long cuttings. Similarly, cuttings collected from the lower and upper portions of shoots resulted in 72.5 and 52.5 per cent rooting respectively, irrespective of auxin treatments. Maximum rooting was observed in the lower portion （40.0%） of cutting com- pared to the upper portion （30.0%） in the control set without auxin treatment. Leafless branches produced maximum （72.0%） rooting compared to the leafy cuttings （35.0%）, irrespective of the auxin treatment. The leafy cuttings produces a minimum of 15.0% sprout- ing and rooting in the control set.

关键词： auxin Dalbergia sissoo length position of shoots type of cuttings vegetative propagation

Effects of mother tree ages, different rooting mediums, light conditions and auxin treatments on rooting behaviour of Dalbergia sissoo branch cuttings

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Journal of Forestry Research 2011年第1期22卷 53-57页

作者： Bhupendra singh Rajendra Yadav B. P. bhatt Department of Forestry Post Box No-59 H.N.B. Garhwal University Srinagar Garhwal - 246 174 Uttarakhand India Chhattisgarh Minor Forest Produce Federation A-25 VIP Estate Khamhardih Shankar Nagar Raipur- 492 007. ICAR Research Complex for NEH Region Nagaland Centre Medziphema- 797 106 Nagaland India

Dalbergia sissoo Roxb. is one of the promising multipurpose tree species of South Asia. Most of the plantations of D. sissoo from seeds are facing severe threats due to the die-back disease, which ultimately causes death of this potential tree-species within a few months. vegetative propagation could avoid the die-back disease. Thirty mother trees of different age-groups of D. sissoo were selected for evaluating the rooting behaviour of branch cuttings from D. sissoo as influenced by auxins （IAA or IBA at 100, 200, 500 mg·L^-1）, ages of mother trees （10, 4 and 2 years old） and different environment conditions, i.e., different mediums （soil and sand） or light conditions （in shade and open condition）. The results show that application of IAA and IBA induced more numbers of cuttings （collected from 10-year-old mother trees） to root compared to control. Branch cuttings of D. sissoo collected from 10-year-old mother trees and planted in soil bed in open conditions had 100.0% of cuttings to root in IAA （100 mg·L^-1） and IBA （200 mg·L^-1） treatments. Both rooting medium （Soil and sand） influenced significantly （p〈0.05） on rooting response of branch cuttings. Soil medium was found to achieve maximum no. of branch cuttings to root, compared to sand medium.

关键词： Dalbergia sissoo hormonal treatments rooting medium shading vegetative propagation branch cutting

Taste masking of ciprofloxacin by ion-exchange resin and sustain release at gastric-intestinal through interpenetrating polymer network

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Asian Journal of Pharmaceutical Sciences 2015年第4期10卷 331-340页

作者： A.Michael Rajesh Shreya A.bhatt Harshad Brahmbhatt Pritpal singh Anand Kiritkumar Mangaldas Popat Reverse Osmosis Membrane Division Central Salt and Marine Chemicals Research InstituteCouncil of Scientific&Industrial Research(CSIR)G.B.MargBhavnagar 364002India Analytical Discipline&Centralized Instrumentation Facility Central Salt and Marine Chemicals Research InstituteCouncil of Scientific&Industrial Research(CSIR)G.B.MargBhavnagar 364002India Academy of Scientific and Innovative Research Central Salt and Marine Chemicals Research InstituteCouncil of Scientific&Industrial Research(CSIR)G.B.MargBhavnagar 364002India

The aim of the study was to taste mask ciprofloxacin(CP)by using ion-exchange resins(IERs)followed by sustain release of CP by forming interpenetrating polymer network(IPN).IERs based on the copolymerization of acrylic acid with different cross linking agents were ***-resin complexes(DRCs)with three different ratios of drug to IERs(1:1,1:2,1:4)were prepared&evaluated for taste masking by following in vivo and in vitro *** volunteers graded ADC 1:4,acrylic acid-divinyl benzene(ADC-3)resin as *** studies such as FTIR,SEM,DSC,P-XRD differentiated ADC 1:4,from physical mixture(PM 1:4)and confirmed the formation of *** vitro drug release of ADC 1:4 showed complete release of CP within 60 min at simulated gastric fluid(SGF)*** *** beads were prepared with ADC 1:4 by using sodium alginate(AL)and sodium alginate-chitosan(AL-CS)for sustain release of CP at SGF pH and followed by simulated intestinal fluid(SIF *** 7.4).FTIR spectra confirmed the formation of IPN *** release of CP was sustain at SGF pH(75%).The kinetic model of IPN beads showed the release of CP was non-Fickian diffusion type.

关键词： Ion exchange resins Biopolymers In vitro&in vivo taste masking Ciprofloxacin Sustain release Release mechanism and kinetics

Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5159-5183页

作者： Vivek Panwar Aishwarya singh Manini bhatt Rajiv K.Tonk Shavkatjon Azizov Agha Saquib Raza Shinjinee Sengupta Deepak Kumar Manoj Garg Department of Pharmaceutical Chemistry School of Pharmaceutical SciencesShoolini UniversitySolanHimachal Pradesh173229India Amity Institute of Molecular Medicine and Stem Cell Research(AIMMSCR) Amity University Uttar PradeshSector-125NoidaUttar Pradesh201313India Department of Biomedical Engineering Indian Institute of TechnologyRoparPunjab140001India Department of Pharmaceutical Chemistry School of Pharmaceutical SciencesDelhi Pharmaceutical Sciences and Research University(DPSRU)New Delhi110017India Laboratory of Biological Active Macromolecular Systems Institute of Bioorganic ChemistryAcademy of Sciences UzbekistanTashkent100125Uzbekistan Faculty of Life Sciences Pharmaceutical Technical University100084TashkentUzbekistan Rajive Gandhi Super Speciality Hospital TahirpurNew Delhi110093India

The mammalian target of rapamycin(mTOR)is a protein kinase that controls cellular metabolism,catabolism,immune responses,autophagy,survival,proliferation,and migration,to maintain cellular *** mTOR signaling cascade consists of two distinct multi-subunit complexes named mTOR complex 1/2(mTORC1/2).mTOR catalyzes the phosphorylation of several critical proteins like AKT,protein kinase C,insulin growth factor receptor(IGF-1R),4E binding protein 1(4E-BP1),ribosomal protein S6 kinase(S6K),transcription factor EB(TFEB),sterol-responsive element-binding proteins(SREBPs),Lipin-1,and Unc-51-like autophagy-activating *** signaling plays a central role in regulating translation,lipid synthesis,nucleotide synthesis,biogenesis of lysosomes,nutrient sensing,and growth factor *** emerging pieces of evidence have revealed that the constitutive activation of the mTOR pathway due to mutations/amplification/deletion in either mTOR and its complexes(mTORC1 and mTORC2)or upstream targets is responsible for aging,neurological diseases,and human ***,we provide the detailed structure of mTOR,its complexes,and the comprehensive role of upstream regulators,as well as downstream effectors of mTOR signaling cascades in the metabolism,biogenesis of biomolecules,immune responses,and ***,we summarize the potential of long noncoding RNAs(lncRNAs)as an important modulator of mTOR ***,we have highlighted the potential of mTOR signaling in aging,neurological disorders,human cancers,cancer stem cells,and drug ***,we discuss the developments for the therapeutic targeting of mTOR signaling with improved anticancer efficacy for the benefit of cancer patients in clinics.

关键词： metabolism homeostasis mTOR

Conservation tillage impacts on soil,crop and the environment

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International Soil and Water Conservation Research 2015年第2期3卷 119-129页

作者： Mutiu Abolanle Busari Surinder singh Kukal Amanpreet Kaur Rajan bhatt Ashura Ally Dulazi Department of Soil Science and Land Management Federal University of AgricultureP.M.B.2240 AbeokutaNigeria Department of Soil Science Punjab Agricultural university141001 LudhianaIndia Ministry of Agriculture Food Security and CooperativesAgriculture Research InstituteMakutuporaDodomaP.O.BOX 1676Tanzania

There is an urgent need to match food production with increasing world population through identification of sustainable land management ***,the struggle to achieve food security should be carried out keeping in mind the soil where the crops are grown and the environment in which the living things *** agriculture(CA),practising agriculture in such a way so as to cause minimum damage to the environment,is being advocated at a large scale *** tillage,the most important aspect of CA,is thought to take care of the soil health,plant growth and the *** paper aims to review the work done on conservation tillage in different agro-ecological regions so as to understand its impact from the perspectives of the soil,the crop and the *** reports have identified several benefits of conservation tillage over conventional tillage(CT)with respect to soil physical,chemical and biological properties as well as crop *** less than 25%of the greenhouse gas effluxes to the atmosphere are attributed to *** of climate change mitigation and adaptation found zero tillage(ZT)to be the most environmental friendly among different tillage ***,conservation tillage involving ZT and minimum tillage which has potential to break the surface compact zone in soil with reduced soil disturbance offers to lead to a better soil environment and crop yield with minimal impact on the environment.&2015 International Research and Training Center on Erosion and Sedimentation and China Water and Power *** and Hosting by Elsevier *** is an open access article under the CC BY-NC-ND license(http://***/licenses/by-nc-nd/4.0/).

关键词： Atmosphere Greenhouse gases Conservation tillage Sustainable crop yield

Radiation dose analysis of computed tomography coronary angiography in Children with Kawasaki disease

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World Journal of Clinical Pediatrics 2023年第4期12卷 230-236页

作者： Mahesh Chandra bhatt Manphool singhal Rakesh Kumar Pilania Subhash Chand Bansal Niranjan Khandelwal Pankaj Gupta Surjit singh Department of Radiodiagnosis and Imaging Postgraduate Institute of Medical Education and ResearchChandigarh 160012India Pediatric Allergy Immunology Unit Department of PediatricsAdvanced Pediatrics CentrePost Graduate Institute of Medical Education and ResearchChandigarh 160012India

BACKGROUND There is evolving role of computed tomography coronary angiography(CTCA)in non-invasive evaluation of coronary artery abnormalities in children with Kawasaki disease(KD).Despite this,there is lack of data on radiation dose in this group of children undergoing *** To audit the radiation dose of CTCA in children with *** Study(December 2013-February 2018)was performed on dual source CT scanner using adaptive prospective *** dose length product(DLP in ***)was *** radiation dose(millisieverts-mSv)was calculated by applying appropriate age adjusted conversion factors as per recommendations of International Commission on Radiological *** dose was compared across the groups(0-1,1-5,5-10,and>10 years).RESULTS Eighty-five children(71 boys,14 girls)with KD underwent *** median age was 5 years(range,2 mo-11 years).Median DLP and effective dose was 21 ***,interquartile ranges(IQR)=15(13,28)and 0.83 mSv,IQR=0.33(0.68,1.01)*** DLP increased significantly across the age *** effective dose in infants(0.63 mSv)was significantly lower than the other age groups(1-5 years 0.85 mSv,5-10 years 1.04 mSv,and>10 years 1.38 mSv)(P<0.05).There was no significant difference in the effective dose between the other groups of *** the CTCA studies were of diagnostic *** child required a repeat *** CTCA is feasible with submillisievert radiation dose in most children with ***,CTCA has the potential to be an important adjunctive imaging modality in children with KD.

关键词： Computed tomography coronary angiography Coronary artery abnormalities Dual source computed tomography Kawasaki disease Radiation exposure

Variation of Trapping Strength with Size and Number of Particles in a Single Trap

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Optics and Photonics Journal 2013年第2期3卷 178-183页

作者： Jitendra bhatt Sachin bhatt Shaival Buch Ravindra Pratap singh Saiyed Nisar Ali Jaaffrey Birla Institute of Technology & Science Pilani - K K Birla Goa Campus Goa India Department of Physics University College of Science Mohan Lal Sukhadia University Udaipur India Indian Institute of Technology Guwahati India Theoretical Physics Division Physical Research Laboratory Ahmedabad India

Optical tweezers use the radiation pressure to trap and manipulate the microscopic particles. Using various algorithms multiple traps are being formed which can trap a number of particles simultaneously. In contrast to multiple traps, many particles can be trapped at a single trap position. It is known that when two or more particles are trapped in a single trap they align themselves in axial direction and it appears as if only one particle is trapped. We present a study of the dependence of the optical trapping force on the number of particles in a single trap using equipartition method;the study was carried out for particles of different sizes. The trapping force was first found to increase then decrease with number of particles in trap for all particle sizes. We feel that our studies will be useful in applications of optical tweezers involving trapping of multiple particles in a single trap.

关键词： Optical Tweezers Multiple Particles Trapping Strength

Synthesis and Biological Activity Study of Novel N1-(4-Hydroxy Benzoyl)-3-Methyl-5-Phenyl-4(N-4-Chlorophenylazo)-1,2-Diazole and Its Derivatives

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Pharmacology & Pharmacy 2017年第1期8卷 1-14页

作者： Sumit bhatt Gajendra singh Sanjeev Kumar Rachna Paliwal Jeet singh Jangwan Chandra Pal singh Department of Chemistry SRT Campus Badshahi Thaul Tehri Garhwal University Campus of HNB Garhwal Central University Shrinagar (Uttarakhand) India Sahu Jain P.G. College Najibabad Department of Chemistry MJP Rohilkhand University Bareilly (Uttar Pradesh) India Hindu College Moradabad Department of Chemistry MJP Rohilkhand University Bareilly (Uttar Pradesh) India

A series of sulpha/substituted derivatives of phenyl azo-1,2-diazole have been synthesized and tested as an anti-inflammatory and anti-bacterial activity in mature albino rats hind paw by taking Diclofenac sodium as standard. N1-(4-hydroxy benzoyl)-3-methyl-5-phenyl-4(N-4-chlorophenylazo)-1,2-diazole is synthesized by a two-step process. In the first step, synthesis of N1-4-chlorophenyl hydrazono-1-methyl-3-phenyl propane-1,3-dione by the reciprocal action of 1-methyl-5-phenylpropane-1,3-dione and diazonium salt solution of phenyl-chloride interacts with 4-hydroxybenzoic acid hydrazide to form the final compound. These diazoles, the heterocyclic compounds which contained electron withdrawing groups, were screened for analgesic activity by acetic acid induced writing method, and for anti-inflammatory activity carried on carrageenan-induced paw edema. The synthesized substituted Chlorophenylazo-1,2-diazole nucleus exhibited significant anti-bacterial, anti-cancer, anti-inflammatory activity, muscle relaxing and moderate activity in anti-proliferative studies.

关键词： 1 2-Diazole Diuretic Activity Muscle Relaxing Anti-Inflammatory Analgesic Antibacterial Activity Anti-Proliferative Studies