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Helium Plasma Effects on Polymer Surfaces:from Plasma Parameters and Surface Properties towards Bioengineering Applications

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Chinese Journal of Polymer Science 2024年第8期42卷 1156-1166页

作者： Andrei vasile Nastuta Maria Butnaru Byron Cheatham Ramona Huzum vasile tiron Ionut Topala Physics and Biophysics Education Research Laboratory(P&B-EduResLab) Biomedical Science DepartmentFaculty of Medical Bioengineering‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Faculty of Medical Bioengineering ‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Cytoviva Inc.570 Devall Drive Suite 301Auburn 36832ALUSA Integrated Center of Environmental Science Studies in the North-Eastern Development Region(CERNESIM) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Research Center on Advanced Materials and Technologies(RAMTECH) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Iasi Plasma Advanced Research Center(IPARC) Faculty of Physics‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania

Plasma treatment is necessary to optimize the performance of biomaterial *** enhances and regulates the performance of biomaterial su rfaces,creating an effective interface with the human *** treatments have the ability to modify the chemical com position and physical structu re of a surface while leaving its properties *** possess the ability to modify material su rfaces,eliminate contaminants,conduct investigations on cancer therapy,and facilitate wound *** subject of study in question involves the integration of plasma science and technology with biology and *** a helium plasma jet source,applying up to 18 kV,with an average power of 10 W,polymer foils were treated for 60 *** treatment has the ability to alter the chemical composition and physical structure of a su rface while maintaining its *** investigation involved the application of helium plasma at atmospheric pressure to polyamide 6 and polyethylene terephthalate *** inquiry involves monitoring and assessing the plasma source and polymer materials,as well as analyzing the impacts of plasma *** the mean power of the discharge aids in assessing the economic efficacy of the plasma *** discharge in helium at atmospheric pressure has beneficial effects in technology,where it increases the surface free energy of polymer *** biomedicine,it is used to investigate cytotoxicity and cell survival,particularly in direct blood exposure situations that can expedite *** the specific parameters that influence the plasma source in the desired manner for the intended application is of utmost im portance.

关键词： Atmopheric pressure plasmas Plasma-polymer interaction Plasma Medicine Plasma diagnosis Polymer characterization

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Lithium niobate waveguides with high-index contrast and preserved nonlinearity fabricated by a high vacuum vapor-phase proton exchange

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Photonics Research 2020年第1期8卷 8-16页

作者： ALICIA PETRONELA RAMBU ALIN MARIAN APETREI FLORENT DOUTRE HERVéTRONCHE vasile tiron MARC DE MICHELI SORIN TASCU Research Center on Advanced Materials and Technologies Science DepartmentInstitute of Interdisciplinary ResearchAlexandru loan Cuza University of Iasi700506 IasiRomania Universite Cote d'Azur CNRSInstitut de Physique de Nice(INPHYNI)UMR 7010NiceFrance Research Department Faculty of PhysicsAlexandru loan Cuza University of Iasi700506 IasiRomania

Highly confining waveguides(Δne>0.1)without a degraded nonlinear coefficient and low propagation losses have been fabricated in lithium niobate(LN)by a new process that we called high vacuum vapor-phase proton exchange(Hi Vac-VPE).Index contrast,index profile,nonlinearity,and crystallographic phases are carefully *** analysis of index profiles indicates that the waveguides contain sub-layers whose depths depend on the exchange *** behavior,propagation losses,and second-harmonic generation response of Hi Vac-VPE channel waveguides are investigated at telecom *** results recommend Hi Vac-VPE as a very promising technique for fabricating efficient nonlinear photonic integrated circuits in LN crystals.

关键词： exchange index nonlinearity

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Solid pancreatic masses:What’s hidden beneath?Insights into rare pancreatic lesions

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World Journal of Clinical Cases 2024年第29期12卷 6255-6257页

作者： Daniel vasile Balaban Department of Internal Medicine and Gastroenterology Carol Davila University of Medicine and PharmacyBucharest 020021Romania

The diagnostic approach to solid pancreatic masses has significantly evolved from the era when a focal pancreatic mass was almost synonymous to pancreatic ductal adenocarcinoma,to a wide spectrum of pancreatic lesions,some of which have good *** the advent of advanced diagnostic tools,particularly refined imaging and tissue acquisition techniques,a broader spectrum of differential diagnoses has been recognized,encompassing conditions ranging from neuroendocrine tumors or inflammatory masses,to rare entities like metastatic clear cell sarcoma or solitary fibrous *** herein discuss case reports of some rare pancreatic lesions,which were diagnosed by combining clinical and imaging features and endoscopic ultrasound-guided tissue sampling and confirmed on surgical *** reports on these rare pancreatic tumors will contribute to a better understanding of their pathogenesis and effective management.

关键词： Pancreatic mass Pancreas Metastasis Diagnosis Endoscopic ultrasound

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Gauge Model Based on Group G×SU（2）

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Chinese Physics Letters 2008年第2期25卷 433-435页

作者： ZET Gheorghe MANTA vasile POPA Camelia Department of Physics Gh. Asachi Technical University Iasi Romania Department of Computers Gh. Asachi Technical University Iasi Romania Faculty of Physics Al. I. Cuza University Iasi Romania

We present a model of gauge theory based on the symmetry group G×SU（2） where G is the gravitational gauge group and SU（2） is the internal group of symmetry. We employ the spacetime of four-dimensional Minkowski, endowed with spherical coordinates, and describe the gauge fields by gauge potentials. The corresponding strength field tensors are calculated and the field equations are written. A solution of these equations is obtained for the case that the gauge potentials have a particular form potentials induces a metric of Schwarzschild type on with spherical symmetry. The solution for the gravitational the gravitational gauge group space.

关键词： pulsars x-ray spectra relativity and gravitation redshift

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Integration and scaling of UV-B radiation effects on plants: the relative sensitivity of growth forms and interspecies interactions

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Journal of Plant Ecology 2018年第4期11卷 656-670页

作者： vasile Alexandru Suchar Ronald Robberecht Department of Statistical Science College of ScienceUniversity of Idaho875 Perimeter Drive MS1104MoscowID 83844-1104USA Department of Forest Rangelandand Fire SciencesCollege of Natural ResourcesUniversity of Idaho875 Perimeter Drive MS1133MoscowID 83844-1133USA

Aims the relative plant type sensitivity and selected community interac-tions under increased UV-B radiation where ***,we investigated:(i)if there are differences among growth forms in regard to their sensitivity to UV-B radiation,(ii)if increased UV-B radiation influences the plant competitive balance in plant com-munities and(iii)the response mechanisms of the UV-B radiation-sensitive species that might increase their *** to answer our research questions,we used a mechanistic model that,for the first time,integrated the effects of increased UV-B radia-tion from molecular level processes,whole plant growth and devel-opment,and community *** Findings In the model simulations,species types exhibited different levels of sensitivity to increased UV-B *** C3 and C4 annuals showed similar growth inhibition rates,while biennials and winter C3 annuals were the most *** exhibited inhibitions in growth only if increased UV-B radiation results in increases in metabolic *** communities,species sensitive to UV-B radiation may have a competitive disadvantage compared to resistant plant ***,sensitive species may have a wide array of responses that can increase their fitness and reproductive success in the com-munity,such as,increased secondary metabolites production,changes in timing of emergence and reproduction,and changes in seed *** individual plants may exhibit significant inhibi-tions in growth and development,in communities,these inhibitions can be mitigated by small morphological and physiological *** or occasional increased UV-B radiation events should not have any lasting effect on the structure of the commu-nity,unless other environmental factors are perturbing the dynamic equilibrium.

关键词： UV-B radiation effects plant growth and development simulation modeling relative sensitivity competition

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Density and thermal expansion coefficients of liquid and austenite phase in lamellar cast iron

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China Foundry 2020年第2期17卷 127-136页

作者： Kristina Hellstrm vasile-Lucian Diaconu Attila Diószegi School of Engineering J.nk.ping UniversitySweden

Volume change related defects formation mechanisms are an important detracting phenomenon in production of complex shaped cast *** different technical alloys,cast iron behaves in a complex manner due to the combined volume change of the formed *** liquid and the austenitic phase are contracting while the graphite phase is expanding during the *** complex volume change in combination with complex casting shapes causes a considerable deviation from isotropy in the solidification *** mentioned difficulties are considered the main reason why an extensive research work is condensed in the literature within this *** multitude of reported experimental set up and the various efforts to interpret the volume change phenomena in terms of density and thermal expansion coefficients makes the results difficult to compare from different *** these difficulties in mind,the present paper presents a broad experimental series and measures unidirectional linear deformation of an industrially spread lamellar cast iron alloy system(Fe-C-2Si)using the push-rod based dilatometer *** measurements are divided into two major groups with respect to the liquid iron deformation over the liquidus temperature line,and the austenite deformation below the solidus temperature *** obtained results are interpreted as thermal expansion coefficients,density variation slopes,and density data at the liquids and solidus *** obtained results are compared with literature data and with calculated values by the Thermo Calc software.

关键词： density thermal expansion coefficient dilatometer castiron Fe-C-2Si CALPHAD

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Mechanical properties of a Gum-type Ti–Nb–Zr–Fe–O alloy

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International Journal of Minerals,Metallurgy and Materials 2017年第8期24卷 909-917页

作者： Anna Nocivin Ion Cinca Doina Raducanu vasile Danut Cojocaru Ion Alexandru Popovici Faculty of Mechanical Industrial and Maritime Engineering Ovidius University of Constanta Faculty of Materials Science and Engineering Politehnica University of Bucharest Carol Davila University of Medicine and Pharmacy

A new Gum-type alloy(Ti–Nb–Zr–Fe–O) in which Fe is used instead of Ta was subjected to a particular thermomechanical processing scheme to assess whether its mechanical characteristics(fine ?-grains with high strength and low modulus) render it suitable as a biomedical implant material. After a homogenization treatment followed by cold-rolling with 50% reduction, the specimens were subjected to one of three different recrystallization treatments at 1073, 1173, and 1273 K. The structural and mechanical properties of all of the treated specimens were analyzed. The mechanical characterization included tensile tests, microhardness determinations, and fractography by scanning electron microscopy. The possible deformation mechanisms were discussed using the Bo – Md diagram. By correlating all of the experimental results, we concluded that the most promising processing variant corresponds to recrystallization at 1073 K, which can provide suitable mechanical characteristics for this type of alloys: high yield and ultimate tensile strengths(1038 and 1083 MPa, respectively), a low modulus of elasticity(62 GPa), and fine crystalline grain size(approximately 50 ?m).

关键词： biomaterials mechanical properties Gum-type alloy thermomechanical processing tensile test

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Progress in Natural Science:Materials International 2015年第2期25卷 122-130页

作者： Valentina Mitran Madalina Georgiana Albu Eugeniu vasile Anisoara Cimpean Marieta Costache University of Bucharest Faculty of Biology Department of Biochemistry and Molecular Biology INCDTP – Division Leather and Footwear Research Institute Collagen Department 3. University Politehnica of Bucharest Advanced Polymer Materials Group

This paper aims at demonstrating the biocompatibility of recently developed 3D hydrogel scaffolds containing the same amount of collagen(COLL) and variable concentrations of sericin(SS) in order to find the most suitable formula for adipose tissue engineering(ATE) *** scaffolds were obtained by COLL crosslinking with glutaraldehyde followed by freeze-drying and, subsequently, seeded with 3T3-L1 preadipocytes. Scanning electron microscopy studies revealed the scaffolds’ architecture and cellular colonization. Also, in vitro biocompatibility of the developed scaffolds was evaluated by LDH and MTT assays and Live/Dead analysis of 3T3-L1 preadipocyte populating these 3D *** best results in terms of cell survival and proliferation status were obtained in the case of the hybrid COLL scaffold containing 40% SS(COLL–SS4). Furthermore, the biological performance of the analyzed COLL-based hydrogels at 5- and 8- days post-seeding was found to decrease as follows: COLL–SS4 4 COLL–SS2 4 COLL 4 COLL–SS6. Consequently, our study highlights that hybrid scaffolds obtained by the addition of variable concentrations of SS to a constant COLL composition positively influences the behavior of 3T3-L1 cells with the exception of the COLL–SS6 matrix(60% SS). Altogether, the data obtained recommend SS as a component of COLL-based hydrogels providing them with features that may be useful in ATE applications.

关键词： Sericin–collagen scaffold Preadipocyte Proliferation Morphology Tissue engineering

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Celiac crisis, a rare occurrence in adult celiac disease: A systematic review

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World Journal of Clinical Cases 2019年第3期7卷 311-319页

作者： Daniel vasile Balaban Alina Dima Ciprian Jurcut Alina Popp Mariana Jinga Department of Internal Medicine and Gastroenterology Carol Davila University of Medicine and Pharmacy Department of Internal Medicine Dr. Carol Davila Central Military Emergency University Hospital Department of Pediatrics Carol Davila University of Medicine and Pharmacy Alessandrescu-Rusescu Institute for Mother and Child Health Center for Child Health Research University of Tampere and Tampere University Hospital

BACKGROUND Celiac crisis(CC), a potentially life-threatening condition, is one of the rare clinical presentations of celiac disease(CD). Several cases have been documented in the literature, mostly in *** To perform a review of CC cases reported in adult CD *** A systematic search of the literature was conducted in two databases,PubMed/MEDLINE and EMBASE, using the term "celiac crisis" and its variant"coeliac crisis", from January 1970 onwards. Altogether, 29 articles reporting 42 biopsy-proven cases were found in the search. Here, we summarized the demographic, clinical characteristics, laboratory and diagnostic work-ups, and therapeutic management in these *** Among the 42 CD cases, the median age was 50 years(range 23-83), with a 2:1 female to male ratio. The majority of patients(88.1%) developed CC prior to CDdiagnosis, while the remaining were previously diagnosed CD cases reporting low adherence to a gluten-free diet(GFD). Clinically, patients presented with severe diarrhea(all cases), weight loss(about two thirds) and, in particular situations, with neurologic(6 cases) or cardiovascular(1 case) manifestations or bleeding diathesis(4 cases). One in four patients had a precipitating factor that could have triggered the CC(e.g. trauma, surgery, infections). Laboratory workup of patients revealed a severe malabsorptive state with metabolic acidosis,dehydration, hypoalbuminemia and anemia. The evolution of GFD was favorable in all cases except one, in whom death was reported due to refeeding *** Celiac crisis is a rare but severe and potentially fatal clinical feature of CD. A high index of suspicion is needed to recognize this clinical entity and to deliver proper therapy consisting of supportive care and, subsequently, GFD.

关键词： Celiac disease Celiac crisis Malabsorption Malnutrition Diarrhea

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Pancreatic involvement in celiac disease

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World Journal of Gastroenterology 2022年第24期28卷 2680-2688页

作者： Daniel vasile Balaban Iulia Enache Marina Ciochina Alina Popp Mariana Jinga Department of Internal Medicine and Gastroenterology Carol Davila University of Medicine and PharmacyBucharest 020021Romania Dr.Carol Davila Central Military Emergency University Hospital Bucharest 020021Romania Department of Pediatrics Carol Davila University of Medicine and PharmacyBucharest 020021Romania National Institute for Mother and Child Health Bucharest 020021Romania

Celiac disease(CD)is well recognized as a systemic,chronic autoimmune disease mainly characterized by gluten-sensitive enteropathy in genetically predisposed individuals but with various extraintestinal *** of the affected organs in CD is the pancreas,consisting of both endocrine and exocrine *** the last decades there has been increasing interest in the pancreatic changes in CD,and this has been reflected by a great number of publications looking at this extraintestinal involvement during the course of *** pancreatic endocrine changes in CD,focusing on type 1 diabetes mellitus,are well documented in the literature,the relationship with the exocrine pancreas has been less *** review summarizes currently available evidence with regard to pancreatic exocrine alterations in CD,focusing on risk of pancreatitis in CD patients,association with autoimmune pancreatitis,prevalence and outcomes of pancreatic exocrine insufficiency in newly diagnosed and gluten-free diet treated CD patients,and the link with cystic *** addition,we discuss mechanisms behind the associated pancreatic exocrine impairment in CD and highlight the recommendations for clinical practice.

关键词： Pancreas Celiac disease Autoimmune Pancreatitis Cystic fibrosis Exocrine insufficiency

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