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Prediction of Pulmonary Arterial Pressure Level after Repair of Congenital Cardiac Communications and Discharge from the Hospital: Role of Down Syndrome and Early Postoperative Hemodynamics

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Congenital Heart Disease 2022年第3期17卷 351-363页

作者： Eloisa Sassa Carvalho Maria Francilene SSouza Kelly Cristina O.Abud Claudia R.P.Castro Juliano G.Penha Ana Maria Thomaz vanessa a.guimaraes Antonio Augusto Lopes Heart Institute(InCor) University of Sao Paulo School of MedicineSão PauloBrazil

Background:Postoperative pulmonary hypertension limits the success of surgical treatment in some patients with unrestrictive congenital cardiac *** patients at risk of developing postoperative pulmonary hypertension is important to individualize follow-up ***:We analyzed a prospective cohort of 52 pediatric patients(age 3 to 35 months)looking for perioperative predictors of mildly elevated pulmonary arterial pressure 6 months after surgery,defined as a systolic pressure greater than 30 mmHg by transthoracic *** corresponds to a mean pulmonary arterial pressure of>20 ***,echocardiographic and hemodynamic parameters were *** hemodynamics was assessed by directly measuring pulmonary and systemic arterial pressures using indwelling *** postoperative pulmonary hemodynamics was defined as the mean pulmonary/systemic mean arterial pressure ratio(PAP/SAP)obtained per patient during the first 6 h of postoperative ***:Among the factors that were investigated as possible predictors,perioperative hemodynamics and the presence of Down syndrome were initially selected using univariate analysis(p0.35 was 76%sensitive and 74%specific at predicting a systolic pulmonary arterial pressure of>30 mmHg 6 months after surgery(hazard ratio with 95%CI 8.972[2.428–33.158],p=0.002).Conclusion:The hypertensive early postoperative behavior of the pulmonary circulation was strongly but not exclusively associated with Down syndrome,and it was char

关键词： Pulmonary hypertension congenital heart disease Down syndrome pediatric cardiac surgery

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Male Breast Cancer-Dosimetry Evaluation in Teletherapy

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2014年第4期3卷 241-251页

作者： Nilmara a.guimaraes Verginia R.Crispim Universidade Federal do Rio de Janeiro UFRJ/CT/COPPE/Programa de Engenharia NuclearRio de JaneiroBrazil

The rate of male breast cancer has increased in recent years, due to the deficiency of preventive examinations (male mammography). Besides, since male breasts are generally smaller than female breasts, it is essential to monitor the doses received by male breasts, as well as those received by close, healthy and critical organs in order to assess the plan used in this kind of treatment. To do this, the distribution of doses in male breasts was simulated and assessed, based on the procedures adopted in the treatment of female breasts, when submitted to a radiation beam from a linear accelerator. The Alderson Rando phantom was used and the relevant absorbed doses were measured by TLD-100 thermoluminescent dosimeters distributed throughout the volume of interest. The results of the treatment planning were compared with the results obtained by TLDs. A difference of up to 8.5%, in comparison with the planned dose, as well as a 6% relative standard deviation was found.

关键词： Radiotherapy Dosimetry Absorbed Dose Teletherapy Metrology

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Pedestrian street and its effect on economic sustainability of a historical Middle Eastern city:The case of Chaharbagh Abbasi in Isfahan,Iran

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Geography and Sustainability 2023年第3期4卷 188-199页

作者： Soudabeh Shahmoradi Sayyed Mahdi Abtahi Pedro guimaraes Department of urban planning Iranian Knowledge-Based Company of Pezhvak Tarh IranianIsfahan Science and Technology TownIsfahan University of Technology BlvdIsfahanIran Department of Civil Engineering Isfahan University of TechnologyIsfahanIran Centre of Geographical Studies Associated Laboratory TERRAInstitute of Geography and Spatial PlanningLisboaPortugal

Pedestrianization is an urban revitalization strategy to enhance sustainability and livability in car-oriented *** many studies in this research field,the effects of pedestrianization on the economy of cities in developing countries still need further ***,the impact of this strategy on the tenant mix of com-mercial and historical areas in Middle East countries is *** address these inadequacies,we considered Chaharbagh Abbasi street,located in the heart of Isfahan,Iran,and investigated the impact of a pedestrianization project with particular emphasis on how it affects the economic sustainability of existent commercial ***-and post-project data along with field observations and quantifications used to assess structural replacements in trade,were analyzed with SPSS and ArcGIS *** results revealed unexpected outcomes,such as the closure of some traditional businesses(27.5%),a stagnation in sales(69%)and a decrease in job offers(84%)leading the local economy to a fragile ***,it was found that the footfall volume increased by 64% and 73% from the retailers’and pedestrians’*** evolution along with a wide opening of food and beverage stores(approximately 60%)makes the post-pedestrianization results more promising than earlier *** conclusion,these findings reinforce the importance of pedestrian streets in revitalizing economic activities in historical and commercial areas from the perspective of economic *** to the lack of similar investigations in Middle East countries,these findings can support decision-makers and urban planners to take preventive measures in preserving the diversity of individual small shops for upcoming urban rehabilitation projects in terms of pedestrianization.

关键词： Urban planning Pedestrianization Chaharbagh abbasi Sustainable Development Goals(SDGs) Economic sustainability Historic city centers

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Mechanical design of an ultra-light vertex detector prototype for CEPC

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Radiation Detection Technology and Methods 2022年第2期6卷 159-169页

作者： Jinyu Fu Zhijun Liang Hao Zeng Gang Li Mingyi Dong Huamin Qu Joao guimaraes da Costa Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics.Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China

Background The Circular Electron Positron Collider(CEPC)is a large international scientific facility proposed to study the Higgs boson in great *** requires state-of-the-art detectors,including extremely precise vertexing and tracking devices,such as a silicon vertex *** Silicon vertex detector with the precision required by the CEPC has never been built before and needs extensive research and *** paper describes the mechanical design of a vertex detector prototype being built to explore the required technologies and the major *** The exceptional high spatial resolution of the CEPC vertex detector is achievable only with a detector of extremely low mass to limit particle *** paper proposes a mechanical design for the vertex detector prototype,highlighting the choice of low-mass materials,the analysis of support structures,the solution of detector cooling issues,and the drafts of procedures for detector *** The ultra-light support of the ladder(a structural unit of the CEPC vertex detector prototype),which is mainly made of carbon fiber reinforced polymer composite,has been *** fabrication process has also been *** supporting and cooling method of the vertex detector prototype has been designed and chosen with results from finite element analysis and computational fluid dynamics *** assembly and installation schemes for the prototype have been developed,and the respective tooling has also been *** performance of the vertex detector prototype,using this low-mass mechanical structure,was demonstrated with fast simulation to closely meet the CEPC physics requirement.

关键词： CEPC Silicon detector Mechanical design Carbon fiber reinforced polymer

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Taenidium barretti ichnofabric and rainfall seasonality:Insights into dryland suites of Scoyenia ichnofacies

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Journal of Palaeogeography 2023年第1期12卷 28-49页

作者： Diego Luciano Nascimento Renata.guimaraes Netto Alessandro Batezelli Francisco Sergio Bernardes Ladeira Daniel Sedorko ICHNOS Research Group Geology Graduate ProgramUnisinos UniversityAv.Unisinos95010 Sao LeopoldoRS93022-750Brazil Campinas State University Geology and Natural Resources DepartmentZeferino Vaz University CityBarao GeraldoCampinasSP13083-970Brazil Laboratory of Pedology(LABPED) Department of GeographyGeosciences InstituteGeosciencesState University of CampinasCampinasSP13083-855Brazil Museu Nacional Departamento de Geologia e PaleontologiaUniversidade Federal do Rio de Janeiro.Horto BotanicoParque Quinta da Boa VistaR.Gen.Herculano Gomes1340Sao CristovaoRio de JaneiroRJ20940-040Brazil

The present work analyzes the monotypic Taenidium barretti ichnofabric developed in abandoned channels and floodplains to understand its paleoecological significance in highly seasonal fluvial *** data come from the Cretaceous paleosols of the Marília Formation(Bauru Basin,SE Brazil),in which the *** ichnofabric and rhizoliths represent the biotic *** larvae are considered to be the most likely *** tracemakers in these *** intensity and recurrence of bioturbation suggest that the windows of opportunity for beetle population growth were very short and controlled by the progressive substrate desiccation after flood *** characteristics of the trace fossil assemblage suggest soil colonization by r-strategic organisms triggered by flooding events that provided the resource inputs necessary for their living during rainy *** results also show that in fluvial systems with high discharge variations,the boundaries between a“pre-desiccation suite”and a“desiccation suite”in the Scoyenia ichnofacies can be diffuse due to the short duration of colonization windows and progressive terrestrialization of floodplains and ***,the frequency of flooding events,the lowered water table,and the rapidity of substrate desiccation constrained colonization by other burrowers and may be considered as firstorder factors controlling the generation of a monotypic *** ***,the monotypic Taenidium ichnofabric in the Scoyenia ichnofacies context is an ichnomarker of brief windows for colonization in highly seasonal environments.

关键词： Ichnology Paleopedology Continental ichnofacies Meniscate burrows Ichnofabric

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An Endogenous Feedback and Entropy Analysis in Machine Learning Model for Stock’s Return Forecast

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Intelligent Automation & Soft Computing 2023年第6期36卷 3175-3190页

作者： Edson Vinicius Pontes Bastos Jorge Junio Moreira Antunes Lino guimaraes Marujo Peter Fernandes Wanke Roberto Ivo da Rocha Lima Filho Instituto Alberto Luiz Coimbra de Pos-Graduação e Pesquisa de Engenharia-COPPE Universidade Federal do Rio de Janeiro(UFRJ)Rio de Janeiro21941-598Brasil Instituto de Pos-Graduacao em Administracao-Coppead Universidade Federal do Rio de Janeiro(UFRJ)21941-918Brasil

Stock markets exhibit Brownian movement with random,non-linear,uncertain,evolutionary,non-parametric,nebulous,chaotic characteristics and dynamism with a high degree of *** an algorithm to predict returns for decision-making is a challenging *** addition,the choice of vari-ables that will serve as input to the model represents a non-triviality,since it is possible to observe endogeneity problems between the predictor and the predicted ***,the goal is to analyze the endogenous origin of the stock return prediction model based on technical *** this,we structure a feed-for-ward neural *** evaluate the endogenous feedback between the pre-dicted returns and technical analysis indicators based on the generated *** is possible to predict the *** high accuracy of the model indicates that,during the test period,there is a hit rate close to 76%.Regarding endogeneity,the term of interest and the return are the variables that influence the largest number of *** results will help investors build investment strategies based on this expert system applied to forecasting.

关键词： Forecast endogeneity neural networks differential evolution stochastic optimization

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Choosing the best endoscopic approach for post-bariatric surgical leaks and fistulas:Basic principles and recommendations

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World Journal of Gastroenterology 2023年第7期29卷 1173-1193页

作者： Victor Lira de Oliveira Alexandre Moraes Bestetti Roberto Paolo Trasolini Eduardo guimaraes Hourneaux de Moura Diogo Turiani Hourneaux de Moura Serviço de Endoscopia Gastrointestinal Departamento de GastroenterologiaHospital das Clínicas da Faculdade de Medicina da Universidade de São PauloSão Paulo 05403010Brazil Division of Gastroenterology Hepatology and EndoscopyHarvard Medical SchoolBrigham and Women's HospitalBostonMA 021115United States

Post-surgical leaks and fistulas are the most feared complication of bariatric *** have become more common in clinical practice given the increasing number of these procedures and can be very difficult to *** two related conditions must be distinguished and characterized to guide the appropriate *** is defined as a transmural defect with communication between the intra and extraluminal compartments,while fistula is defined as an abnormal communication between two epithelialized ***,surgical treatment was the preferred approach for leaks and fistulas and was associated with high morbidity with significant mortality ***,with the development of novel devices and techniques,endoscopic therapy plays an increasingly essential role in managing these *** diagnosis and endoscopic therapy initiation after clinical stabilization are crucial to success since clinical success rates are higher for acute leaks and fistulas when compared to late and chronic leaks and *** endoscopic techniques are available with different mechanisms of action,including direct closure,covering/diverting or *** treatment should be individualized by considering the characteristics of both the patient and the *** there is a lack of high-quality studies to provide standardized treatment algorithms,this narrative review aims to provide a summary of the current scientific evidence and,based on this data and our extensive experience,make recommendations to help choose the best endoscopic approach for the management of post-bariatric surgical leaks and fistulas.

关键词： Endoscopy Surgery Bariatric Gastrointestinal Fistulas Leaks

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Mathematical simulation of radial heat transfer in packed beds by pseudohomogeneous modeling

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Particuology 2011年第2期9卷 107-113页

作者： Rodrigo Béttega Marcos Flávio Pinto Moreira Ronaldo guimaraes Corrêa José Teixeira Freire Federal University of Uberlandia/School of Chemical Engineering-Av.Jo o Naves ávila 2121 Uberlandia-MGCEP 38400-902Brazil Western Paraná State University-Rua da Faculdade 645 Jardim La SalleToledo-PRCEP 85903-000Brazil Federal University of S o Carlos/Department of Chemical Engineering-Rod.Washington Luiz km 235 S o Carlos-SPCEP 13565-905P.O.Box 676Brazil

Uniform flow regime and constant effective thermal conductivity inside packed beds are commonly accepted in the evaluation of the fluid dynamics and heat transfer in such systems. However, several authors have confirmed the presence of an oscillatory velocity profile caused by the effective contribu~ tion of porosity profile in the fluid dynamic behavior of packed beds, which directly influences the heat transfer inside the beds. This paper describes the application of a pseudo-homogeneous mathematical model for describing heat transfer in packed beds with oscillatory profiles of velocity and porosity, using a radius-dependent model for effective thermal conductivity kr. Several temperature profiles were obtained in a packed bed system with thermal source located on the wall. The simulated temperature and effective thermal conductivity obtained from simulations were compared with experimental data and calculation from a model based on uniform kr fitting. The results indicate that the proposed mathematical modeling was capable of better reDresenting the heat transfer in the packed bed.

关键词： Packed bedHeat transferPseudohomogeneous modeling

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绝对动脉期超增强能否提高CT对不确定结节中肝细胞癌检测的敏感性

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国际医学放射学杂志 2024年第3期 377-377页

作者： S.Zafar K.Y.Elbanna A.W.M.Todd L.guimaraes C.O'Brien A.Goel 余翔玲

摘要目的确定在CT上对不确定性结节进行相对（R）和绝对（A）动脉期过度增强（APHE）和廓清（WO）的定量评估，能否提高肝细胞癌（HCC）检测的总体敏感性。方法回顾

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Short-term complementary and alternative medicine on quality of life in women with fibromyalgia

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Journal of Integrative Medicine 2016年第1期14卷 29-35页

作者： Paulo Araujo Dias Andre Brito Bastos guimaraes Andrea de Oliveira Albuquerque Karoline Lucas de Oliveira Maria Luzete Costa Cavalcante Sergio Botelho guimaraes Faculty of Medicine Department of SurgeryFederal University of Ceara60430-140FortalezaBrazil Faculty of Pharmacy Dentistry and NursingFederal University of Ceara60430-160FortalezaBrazil

BACKGROUND： Fibromyalgia （FMS） is a syndrome characterized by chronic widespread musculoskeletal pain, whose etiology is not completely understood. Different therapeutic approaches have been used with inconsistent results. This observation does not invalidate the continued search for alternative treatments aimed at improving quality of life （QoL） in FMS. OBJECTIVE： This study compared three classica acupuncture （AC）, electroacupuncture （EAC） and promotion of QoL in FMS patients. traditional Chinese medicine （TCM） therapies： moxibustion （MX） in the management of pain and DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： A preliminary, group-assigned, comparative study enrolled 30 women, mean age （46.90_＋9.24） years （range 20-60 years）, who met the 1990 American College of Rheumatology criteria for FMS diagnosis and a pain-pressure threshold （PPT）〈 4 kg/cm2. The study was conducted in a teaching tertiary-care medical institution from May 2010 through April 2012. AC, EAC and MX were delivered for 30 min, once a week, for 8 weeks, bilaterally at Neiguan （PC6）, Hegu （LI4）, Yanglingquan （GB34）, Sanyinjiao （SP6） and Taichong （LR3） acupoints. MAIN OUTCOME MEASURES： Each week, immediately before treatment and after treatment, subjects were tested for PPTs, Wong-Baker Faces Pain Scale （WBFPS; for pain intensity） and Medical Outcomes Study 36-item Short Form Health Survey （SF-36： for QoL）. RESULTS： There was no significant improvement in pain or reduction of tender points in any of the groups studied, at the end of the 8th session. Significant improvement of QoL was perceived in vitality （after AC treatment） and in mental health （after EAC and MX treatments）. CONCLUSION： TCM therapies （AC, EAC and MX） promoted an improvement in the QoL in two areas （vitality and mental health） in FMS women. Further large-scale clinical trials are required to confirm this effect.

关键词： quality of life medicine, Chinese traditional acupuncture therapy women

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