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Journal of Bionic Engineering 2012年第4期9卷 391-401页

作者： Hoang Vu Phan Quoc Viet Nguyen Quang Tri truong Tien van truong Hoon Cheol Park Nam Seo Goo Doyoung Byun Min Jun Kim Department of Advanced Technology Fusion Konkuk University Seoul 143-701 Korea Department of Aerospace Engineering Konkuk University Seoul 143-701 Korea Department of Mechanical Engineering Sungkyunkwan University Seoul 143-701 Korea Department of Mechanical Engineering and Mechanics Drexel University Philadelphia USA

We briefly summarized how to design and fabricate an insect-mimicking flapping-wing system and demonstrate how to implement inherent pitching stability for stable vertical takeoff. The effect of relative locations of the Center of Gravity （CG） and the mean Aerodynamic Center （AC） on vertical flight was theoretically examined through static force balance considera- tion. We conducted a series of vertical takeoff tests in which the location of the mean AC was determined using an unsteady Blade Element Theory （BET） previously developed by the authors. Sequential images were captured during the takeoff tests using a high-speed camera. The results demonstrated that inherent pitching stability for vertical takeoff can be achieved by controlling the relative position between the CG and the mean AC of the flapping system.

关键词： beetle flapping-wing system insect-mimicking insect flight inherent pitching stability vertical takeoff

Historical development of karst evergreen broadleaved forests in East Asia has shaped the evolution of a hemiparasitic genus Brandisia(Orobanchaceae)

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Plant Diversity 2023年第5期45卷 501-512页

作者： Zhe Chen Zhuo Zhou Ze-Min Guo truong van Do Hang Sun Yang Niu CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of Sciences132 Lanhei RoadKunming 650201YunnanChina University of Chinese Academy of Sciences Beijing 100049China Vietnam National Museum of Nature Vietnam Academy of Science and Technology18 Hoang Quoc VietCau Giay 10000HanoiVietnam Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc VietCau Giay 10000HanoiVietnam

Brandisia is a shrubby genus of about eight species distributed basically in East Asian evergreen broadleaved forests(EBLFs),with distribution centers in the karst regions of Yunnan,Guizhou,and Guangxi in southwestern *** on the hemiparasitic and more or less liana habits of this genus,we hypothesized that its evolution and distribution were shaped by the development of EBLFs *** test our hypothesis,the most comprehensive phylogenies of Brandisia hitherto were constructed based on plastome and nuclear loci(nrDNA,PHYA and PHYB);then divergence time and ancestral areas were inferred using the combined nuclear loci *** analyses reconfirmed that Brandisia is a member of Orobanchaceae,with unstable placements caused by nuclear-plastid *** Brandisia,three major clades were well supported,corresponding to the three subgenera based on *** was inferred to have originated in the early Oligocene(32.69 Mya)in the Eastern Himalayas-SW China,followed by diversification in the early Miocene(19.45 Mya)in karst *** differentiation dates of Brandisia were consistent with the origin of keystone species of EBLFs in this region(e.g.,Fagaceae,Lauraceae,Theaceae,and Magnoliaceae)and the colonization of other characteristic groups(e.g.,Gesneriaceae and Mahonia).These findings indicate that the distribution and evolution of Brandisia were facilitated by the rise of the karst EBLFs in East *** addition,the woody and parasitic habits,and pollination characteristics of Brandisia may also be the important factors affecting its speciation and dispersal.

关键词： Biogeography Brandisia Evergreen broadleaved forests(EBLFs) Karst Orobanchaceae Phylogeny

Non-Jumping Take off Performance in Beetle Flight （Rhinoceros Beetle Trypoxylus dichotomus）

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Journal of Bionic Engineering 2014年第1期11卷 61-71页

作者： Tien van truong Tuyen Quang Le Hoon Cheol Park Kwang Joon Yoon Min Jun Kim Doyoung Byun Department of Aerospace and Information Engineering Konkuk University Seoul South Korea Department of Mechanical Engineering National University of Singapore Singapore KoreaInstitute of Ocean Science and Technology PO Box 29 Ansan 425-600 South Korea Department of Advanced Technology Fusion Konkuk University Seoul South Korea Department of Mechanical Engineering and Mechanics Drexel University Philadelphia PA 19104 USA Department of Mechanical Engineering Sungkyunkwan University Suwon South Korea

In recent decades, the take-off mechanisms of flying animals have received much attention in insect flight initiation. Most of previous works have focused on the jumping mechanism, which is the most common take-off mechanism found in flying animals. Here, we presented that the rhinoceros beetle, Trypoxylus dichotomus, takes offwithout jumping. In this study, we used 3-Dimensional （3D） high-speed video techniques to quantitatively analyze the wings and body kinematics during the initiation periods of flight. The details of the flapping angle, angle of attack of the wings and the roll, pitch and yaw angles of the body were investigated to understand the mechanism of take-off in T. dichotomus. The beetle took off gradually with a small velocity and small acceleration. The body kinematic analyses showed that the beetle exhibited stable take-off. To generate high lift force, the beetle modulated its hind wing to control the angle of attack; the angle of attack was large during the upstroke and small during the downstroke. The legs of beetle did not contract and strongly release like other insects. The hind wing could be con- sidered as a main source of lift for heavy beetle.

关键词： take-oft non-jumping mechanism rhinoceros beetle kinematics

Flow Visualization of Rhinoceros Beetle （Trypoxylus dichotomus） in Free Flight

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Journal of Bionic Engineering 2012年第3期9卷 304-314页

作者： Tien van truong Tuyen Quang Le Hieu Trung Tran Hoon Cheol Parka Kwang Joon Yoon Doyoung Byun . Department of Aerospace Information Engineering Konkuk University Seoul 143-70 l Republic of Korea 2.Costal Engineering and Ocean Energy Research Department Korea Ocean Research and Development Institute 454 Haeanro Sangrok-gu Ansan 426-744 Republic of Korea Department of Advanced Technology Fusion Konkuk University Seoul 143-701 Republic of Korea Department of Mechanical Engineering Sungkyunkwan University Suwon 440-746 Republic of Korea

Aerodynamic characteristics of the beetle, Trypoxylus dichotomus, which has a pair of elytra （forewings） and flexible hind wings, are investigated. Visualization experiments were conducted for various flight conditions of a beetle, Trypoxylus di- chotomus： free, tethered, hovering, forward and climbing flights. Leading edge, trailing edge and tip vortices on both wings were observed clearly. The leading edge vortex was stable and remained on the top surface of the elytron for a wide interval during the downstroke of free forward flight. Hence, the elytron may have a considerable role in lift force generation of the beetle. In addition, we reveal a suction phenomenon between the gaps of the hind wing and the elytron in upstroke that may improve the positive lift force on the hind wing. We also found the reverse clap-fling mechanism of the T. dichotomus beetle in hovering flight. The hind wings touch together at the beginning of the upstroke. The vortex generation, shedding and interaction give a better understanding of the detailed aerodynamic mechanism of beetle flight.

关键词： beetle smoke wire visualization free flight hovering flight wing interaction elytron effect

Autophagy modulates physiologic and adaptive response in the liver

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Liver Research 2023年第4期7卷 304-320页

作者： Trinh van Le Nhung Hai truong Ai Xuan L.Holterman Laboratory of Stem Cell Research and Application University of Science-VNUHCMHo Chi Minh CityVietnam Vietnam National University Ho Chi Minh CityVietnam Faculty of Biology and Biotechnology University of Science-VNUHCMHo Chi Minh CityVietnam Department of Pediatrics and Surgery University of Illinois College of MedicineChicago and PeoriaILUSA

Autophagy is a physiological process that is ubiquitous and essential to the disposal or recycling of damaged cellular organelles and misfolded proteins to maintain organ homeostasis and *** importance in the regulation of liver function in normal and pathological conditions is increasingly *** review summarizes how autophagy regulates epithelial cell-and non-epithelial cellspecific function in the liver and how it differentially participates in hepatic homeostasis,hepatic injury response to stress-induced liver damage such as cholestasis,sepsis,non-alcoholic and alcohol-associated liver disease,viral hepatitis,hepatic fibrosis,hepatocellular and cholangiocellular carcinoma,and ***-based interventional studies for liver diseases that are currently registered in *** are *** the broad and multidirectional autophagy response in the liver,a more refined understanding of the liver cell-specific autophagy activities in a context-dependent manner is necessary。

关键词： Autophagy Biliary epithelial cell Hepatitis Hepatocellular carcinoma Hepatic stellate cell Hepatocyte

Brunner’s gland hyperplasia associated with lipomatous pseudohypertrophy of the pancreas presenting with gastrointestinal bleeding:A case report

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World Journal of Clinical Cases 2021年第31期9卷 9670-9679页

作者： long Cong Nguyen Khanh truong Vu Trang Thi Thuy Vo Chau Ha Trinh Tan Dang Do Ngoc Thi van Pham Tuyen van Pham Thanh Tuan Nguyen Hiep Canh Nguyen Jeong-Sik Byeon Gastroenterology and Hepatology Center Bach Mai HospitalHanoi 10000Viet Nam Department of Gastroenterology School of Medicine and PharmacyVietnam National University HanoiHanoi 10000Viet Nam Radiology Center Bach Mai HospitalHanoi 10000Viet Nam Pathology Center Bach Mai HospitalHanoi 10000Viet Nam Department of Human Pathology Kanazawa University Graduate School of MedicineKanazawa 920-8640Japan Department of Gastroenterology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Brunner’s gland hyperplasia(BGH)is a rare benign lesion of the *** pseudohypertrophy(LiPH)of the pancreas is an extremely rare *** each condition is rare,the probability of purely coincidental coexistence of both conditions is extremely *** SUMMARY We report a 26-year-old man presenting to our hospital with symptoms of recurrent upper gastrointestinal *** gastrointestinal endoscopy showed a huge pedunculated polypoid lesion in the duodenum with bleeding at the base of the *** examination of the duodenal biopsy specimens showed ***,abdominal computed tomography and magnetic resonance imaging revealed marked fat replacement over the entire pancreas,confirmed by histopathological evaluation on percutaneous pancreatic *** on the radiological and histological findings,LiPH of the pancreas and BGH were *** patient refused any surgical ***,he was managed with supportive *** patient’s symptoms improved and there was no further *** This is the first well-documented case showing the coexistence of LiPH of the pancreas and BGH.

关键词： Lipomatous pseudohypertrophy Pancreas Gastrointestinal bleeding Brunner’s gland Case report

A new species of the genus Leptolalax (Anura： Megophryidae) from southern Vietnam

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Zoological Research 2018年第3期39卷 185-201页

作者： Tang van Duong Dang Trong Do Chung Dac Ngo truong Quang Nguyen Nikolay A. Poyarkov Vietnam National Museum of Nature Vietnam Academy of Science and Technology Hanoi Vietnam Department of Vertebrate Zoology Biological FacultyLomonosov Moscow State University Moscow 119234 Russia Faculty of Natural Sciences Phu Yen University Tuy Hoa Phu Yen Vietnam College of Education Hue University Hue Vietnam Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology Hanoi Vietnam Graduate University of Science and Technology Vietnam Academy of Science and Technology Cau Giay Hanoi Vietnam Joint Russian- Vietnamese Tropical Research and Technological Center Nghia Do Cau Giay Hanoi Vietnam

We describe a new species of megophryid frog from Phu Yen Province in southern Vietnam. Leptolalax macrops sp. nov. is distinguished from its congeners by a combination of the following morphological attributes：（1） body size medium （SVL 28.0-29.3 mm in three adult males, 30.3 mm in single adult female）; （2） supra-axillary glands present, creamy white; ventrolateral glands indistinct; （3） tympanum externally distinct; （4） dorsal skin roughly granular with larger tubercles, dermal ridges on dorsum absent; （5） rudimentary webbing present between fingers I-II and I1-111; rudimentary webbing between all toes; fingers and toes without dermal fringes; （6） in life ventral surface greyish-violet with white speckling; （7） supratympanic fold distinct, dark brown in life; （8） iris bicolored, typically golden in upper half, fading to golden green in lower half; （9） tibia short （TbL/SVL 0.44-0.45 in males）; and （10） eyes large and protuberant （ED/SVL 0.15-0.16 in males） From all congeners for which comparable sequences are available, the new species differs markedly in the 16S rRNA mitochondrial gene sequence （P-distance〉5.7%）. The new species is currently known only from montane evergreen tropical forests of Song Hinh District, Phu Yen Province, and M＇Drak District of Dak Lak Province at elevations of 470-630 m a.s.l.. We suggest the new species should be considered as Data Deficient following the IUCN＇s Red List categories. We also report a previously unknownLeptolalax mtDNA lineage from an evergreen tropica forest in the Hoa Thinh District of Phu Yen Province which may also represent an undescribed species.

关键词： Leptolalax macrops sp. nov. Phu YenProvince Dak Lak Province Southern coastal regionof Vietnam

How Could Beetle＇s Elytra Support Their Own Weight during Forward Flight？

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Journal of Bionic Engineering 2014年第4期11卷 529-540页

作者： Tuyen Quang Le Tien van truong Hieu TrungTran Soo Hyung Park Jin Hwan Ko Hoon Cheol Park Doyoung Byun Korea Institute of Ocean Science and Technology Ansan P. O. Box 29 425-600 South Korea Institute of High Performance Computing 1 Fusionopolis Way Singapore 138632 Singapore Department of Aerospace and Information Engineering Konkuk University Seoul South Korea Department of Mechanical Engineering National University of Singapore Singapore Department of Advanced Technology Fusion Konkuk University Seoul South Korea Department of Mechanical Engineering Sungkyunkwan University Suwon South Korea

The aerodynamic role of the elytra during a beetle＇s flapping motion is not well-elucidated, although it is well-recognized that the evolution of elytra has been a key in the success of coleopteran insects due to their protective function. An experimental study on wing kinematics reveals that for almost concurrent flapping with the hind wings, the flapping angle of the elytra is 5 times smaller than that of the hind wings. Then, we explore the aerodynamic forces on elytra in free forward flight with and without an effect of elytron-hind wing interaction by three-dimensional numerical simulation. The numerical results show that vertical force generated by the elytra without interaction is not sufficient to support even its own weight. However, the elytron-hind wing interaction improves the vertical force on the elytra up to 80%; thus, the total vertical force could fully support its own weight. The interaction slightly increases the vertical force on the hind wind by 6% as well.

关键词： wing interaction elytra beetle free forward flight three-dimensional numerical simulation

Prevention of DNA re-replication in eukaryotic cells

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分子细胞生物学报:英文版 2011年第1期3卷 13-22页

作者： Lan N.truong Xiaohua Wu Department of Molecular and Experimental Medicine The Scripps Research InstituteLa JollaCA 92037USA

DNA replication is a highly regulated process involving a number of licensing and replication factors that function in a carefully orchestrated manner to faithfully replicate DNA during every cell *** of proper licensing control leads to deregulated DNA replication including DNA re-replication,which can cause genome instability and *** organisms have established several conserved mechanisms to prevent DNA re-replication and to counteract its potentially harmful *** mechanisms include tightly controlled regulation of licensing factors and activation of cell cycle and DNA damage *** licensing control and its associated compromised checkpoints have both been observed in tumor cells,indicating that proper functioning of these pathways is essential for maintaining genome *** this review,we discuss the regulatory mechanisms of licensing control,the deleterious consequences when both licensing and checkpoints are compromised,and present possible mechanisms to prevent re-replication in order to maintain genome stability.

关键词： DNA re-replication cell cycle checkpoints DNA damage response Cdt1 DSB repair genome stability tumorigenesis

First Records of Megophrys daweimontis Rao and Yang, 1997 and Amolops vitreus(Bain, Stuart and Orlov, 2006)(Anura: Megophryidae, Ranidae) from Vietnam

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Asian Herpetological Research 2015年第1期6卷 66-72页

作者： Dzung Trung LE Anh van PHAM Son Hung Lan NGUYEN Thomas ZIEGLER truong Quang NGUYEN Faculty of Biology Hanoi National University of Education Faculty of Biology and Chemistry Tay Bac University AG Zoologischer Garten Kln Institute of Ecology and Biological Resources Vietnam Academy of Science and Technology

Two amphibian species,Megophrys daweimontisandAmolops vitreus,are recorded for the ifrst time from Vietnam, on the basis of a new amphibian collection from Dien Bien and Son La provinces. In addition, acoustic analysis ofA. vitreus is also provided based on the advertisement calls recorded in Muong Nhe Nature Reserve of Dien Bien Province, Vietnam.

关键词： Amolops vitreus Megophrys daweimontis new records advertisement call Dien Bien Province Son La Province