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The association of diet quality and physical activity with cardiovascular disease and mortality in 85,545 older Australians:A longitudinal study

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Journal of Sport and Health Science 2024年第6期13卷 841-850页

作者： Ding Ding Joe van buskirk Stephanie Partridge Philip Clare Edward Giovannucci Adrian Bauman Nicole Freene Robyn Gallagher Binh Nguyen Sydney School of Public Health Faculty of Medicine and Healththe University of SydneyCamperdownNSW 2006Australia Charles Perkins Centre the University of SydneyCamperdownNSW 2006Australia Sydney Local Health District CamperdownNSW 2050Australia School of Health Sciences Faculty of Medicine and Healththe University of SydneyCamperdownNSW 2006Australia National Drug and Alcohol Research Centre UNSW SydneySydneyNSW 2052Australia Departments of Nutrition and Epidemiology Harvard T.H.Chan School of Public HealthBostonMA 02115USA Faculty of Health University of CanberraCanberraACT 2617Australia Susan Wakil School of Nursing and Midwifery the University of SydneyCamperdownNSW 2050Australia

Background:A quality diet and an active lifestyle are both important cornerstones of cardiovascular disease(CVD)***,despite their interlinked effects on metabolic health,the 2 behaviors are rarely considered jointly,particularly within the context of CVD *** examined the independent,interactive,and joint associations of diet and physical activity with CVD hospitalization,CVD mortality,and all-cause ***:CVD-free Australian participants aged 4574 years(n=85,545)reported physical activity,diet,sociodemographic,and lifestyle characteristics at baseline(20062009)and follow-up(20122015),and data were linked to hospitalization and death registries(03/31/2019 for CVD hospitalization and all-cause mortality and 12/08/2017 for CVD mortality).Diet quality was categorized as low,medium,and high based on meeting dietary *** activity was operationalized as(a)total moderate-to-vigorous physical activity(MVPA)as per guidelines,and(b)the composition of MVPA as the ratio of vigorous-intensity physical activity(VPA)to total *** used a left-truncated cause-specific Cox proportional hazards model using time-varying ***:During a median of 10.7 years of follow-up,6576 participants were admitted to the hospital for CVD and 6581 died from all causes(876 from CVD during 9.3 years).A high-quality diet was associated with a 17%lower risk of all-cause mortality than a low-quality diet,and the highest MVPA category(compared with the lowest)was associated with a 44%and 48%lower risk of CVD and all-cause mortality,*** interactions between diet and physical activity were *** all outcomes,the lowest risk combinations involved a high-quality diet and the highest MVPA *** for total MVPA,some VPA was associated with further risk reduction of CVD hospitalization and all-cause ***:For CVD prevention and longevity,one should adhere to both a healthy d

关键词： Diet Physical activity Cardiovascular disease Mortality Cohort studies

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Demographic Processes Linked to Genetic Diversity and Positive Selection across a Species’ Range

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Plant Communications 2020年第6期1卷 72-84页

作者： Yvonne Willi Marco Fracassetti Olivier Bachmann Josh van buskirk Department of Environmental Sciences University of BaselSch€onbeinstrasse 6CH-4056 BaselSwitzerland Department of Evolutionary Biology and Environmental Studies University of Z€urichCH-8057 Z€urichSwitzerland Department of Ecology Environment and Plant SciencesScience for Life LaboratoryStockholm UniversitySE-10691 StockholmSweden

Demography determines the strength of genetic drift,which generally reduces genetic variation and the efficacy of ***,we disentangled the importance of demographic processes at a local scale(census size and mating system)and at a species-range scale(old split between population clusters,recolonization after the last glaciation cycle,and admixture)in determining within-population genomic diversity and genomic signatures of positive *** were based on re-sequence data from 52 populations of North American Arabidopsis lyrata collected across its entire *** mating system and range dynamics since the last glaciation cycle explained around 60%of the variation in genomic diversity among populations and 52%of the variation in the signature of positive *** was lowest in selfing compared with outcrossing populations and in areas further away from glacial *** parallel,reduced positive selectionwas found in selfing populations and in populations with a longer route of postglacial range *** signature of positive selection was also reduced in populations without *** conclude that recent range expansion can have a profound influence on diversity in coding and non-coding DNA,similar in magnitude to the shift toward *** limits may in fact be caused by reduced effective population size and compromised positive selection in recently colonized parts of the range.

关键词： admixture-dependent selection directional selection genetic drift range expansion selfing small population size

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激光小梁成形术的病理生理学

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国外医学（眼科学分册） 1989年第6期13卷 257-260页

作者： E.Michael van buskirk 嵇训传

氩激光小梁成形术对小梁网的确切作用,尚未完全明了。业经大量资料证实,其降压效果系通过改善房水外流。从临床上看,该效应似与激光的特性(包括:波形、波长、烧灼部位、治疗时间,甚至在一定程度上还包括激光的能量)均不具特异性。其降... 详细信息

氩激光小梁成形术对小梁网的确切作用,尚未完全明了。业经大量资料证实,其降压效果系通过改善房水外流。从临床上看,该效应似与激光的特性(包括:波形、波长、烧灼部位、治疗时间,甚至在一定程度上还包括激光的能量)均不具特异性。其降压反应延迟发生,随时间减弱,有些病例可因再次治疗而重新获得降压效果。激光光凝对小梁网在聚焦焦点上产生破坏,但漫射则可兴奋小梁网细胞。激光治疗后小梁网形状改变,只有在眼压很高时才可能有助于房水外流。很可能细胞兴奋激活某种分子生物链变化,或许在小梁细胞外间质,从而改善房水外流易度。

关键词：激光小梁成形术病理生理学 ALTP

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