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Polar Gini Curve:A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data

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Genomics, Proteomics & Bioinformatics 2021年第3期19卷 493-503页

作者： Thanh minh nguyen Jacob John Jeevan Nuo Xu Jake Y.Chen Informatics Institute the University of Alabama at BirminghamBirminghamAL 35294USA Collat School of Business the University of Alabama at BirminghamBirminghamAL 35294USA

In this work,we describe the development of Polar Gini Curve,a method for characterizing cluster markers by analyzing single-cell RNA sequencing(scRNA-seq)*** Gini Curve combines the gene expression and the 2D coordinates(“spatial”)information to detect patterns of uniformity in any clustered cells from scRNA-seq *** demonstrate that Polar Gini Curve can help users characterize the shape and density distribution of cells in a particular cluster,which can be generated during routine scRNA-seq data *** quantify the extent to which a gene is uniformly distributed in a cell cluster space,we combine two polar Gini curves(PGCs)—one drawn upon the cell-points expressing the gene(the“foreground curve”)and the other drawn upon all cell-points in the cluster(the“background curve”).We show that genes with highly dissimilar foreground and background curves tend not to uniformly distributed in the cell cluster—thus having spatially divergent gene expression patterns within the *** with similar foreground and background curves tend to uniformly distributed in the cell cluster—thus having uniform gene expression patterns within the *** quantitative attributes of PGCs can be applied to sensitively discover biomarkers across clusters from scRNA-seq *** demonstrate the performance of the Polar Gini Curve framework in several simulation case *** this framework to analyze a real-world neonatal mouse heart cell dataset,the detected biomarkers may characterize novel subtypes of cardiac muscle *** source code and data for Polar Gini Curve could be found at http://***/PGC/or https://***/projects/Polar_Gini_Curve/76749.

关键词： Single-cell gene expression Polar Gini curve Spatial pattern Biomarker discovery

A Raman Study of the Origin of Oxygen Defects in Hexagonal Manganite Thin Films

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Chinese Physics Letters 2012年第12期29卷 148-151页

作者： CHEN Xiang-Bai HIEN nguyen Thi minh YANG In-Sang LEE Daesu NOH Tae-Won Department of Nano Science&Mechanical Engineering and Nanotechnology Research Center Konkuk UniversityChungju 380-701Korea 2Department of Physics and Division of Nano-SciencesEwha Womans UniversitySeoul 120-750Korea 3ReCFIDepartment of Physics and AstronomySeoul National UniversitySeoul 151-747Korea

Oxygen defects are usually unavoidable when synthesizing oxide thin *** study the origin of the oxygen defects in hexagonal manganite HoMnO_(3) epitaxial thin films through Raman scattering *** results show that the oxygen defects in hexagonal HoMnO_(3) thin films have distinct effects on different phonon modes and on magnon *** analyses indicate that the oxygen defects in hexagonal HoMnO_(3) thin films mainly originate from the basal O3 and/or O4 oxygen ***,our analyses of oxygen defects predict that the Mn 3d orbitals would be more strongly hybridized with the apical O1 and/or O22p orbitals than the basal O3 and/or O42p *** prediction is consistent with our resonant Raman scattering study and earlier first-principle calculations of the electronic structures of hexagonal manganites.

关键词： spectroscopy. hexagonal Oxygen

Formability improvement and blank shape definition for deep drawing of cylindrical cup with complex curve profile from SPCC sheets using FEM

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Journal of Central South University 2014年第1期21卷 27-34页

作者： Duc-Toan nguyen Duy-Khoe Dinh Hong-minh Thi nguyen Tien-Long Banh Young-Suk Kim School of Mechanical Engineering Hanoi University of Science and Technology1A-Dai Co Viet StreetHai Ba Trung DistrictHanoi CityVietnam Department of Mechanical Engineering Hungyen University of Technology and EducationHungyenVietnam Department of Mechanical Engineering Kyungpook National University1370 SangyeokBuk-kuDaegu 702-701Korea

In the current work, to predict and improve the formability of deep drawing process for steel plate cold rolled commercial grade （SPCC） sheets, three parameters including the blanking force, the die and punch comer radius were considered. The experimental plan according to Taguchi＇s orthogonal array was coupled with the finite element method （FEM） simulations. Firstly, the data from the test of stress-strain and forming limit curves were used as input into ABAQUS/Explicit finite element code to predict the failure occurrence of deep drawing process. The three parameters were then validated to establish their effects on the press formability. The optimum case found via simulation was finally confirmed through an experiment. In order to obtain the complex curve profile of cup shape after deep drawing, the anisotropic behavior of earring phenomenon was modeled and implemented into FEM. After such phenomenon was correctly predicted, an error metric compared with design curve was then measured.

关键词： finite element method SPCC deep-drawing forming limit diagram criterion Taguchi's method earring prediction

A combination of damage locating vector method （DLV） and differential evolution algorithm （DE） for structural damage assessment

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Frontiers of Structural and Civil Engineering 2018年第1期12卷 92-108页

作者： T. nguyen-THOI A. TRAN-VIET N. nguyen-minh T. VO-DUY V. HO-HUU Division of Computational Mathematics and Engineering Institute for Computational Science Ton Duc Thang University Hochiminh City Vietnam Division of Construction Computation Institute for Computational Science Ton Duc Thang University Hochiminh City Vietnam Faculty of Civil Engineering Ton Duc Thang University Hochiminh City Vietnam

In this study, a two-stage method is presented for identifying multiple damage scenarios. In the first stage, the damage locating vector （DLV） method using normalized cumulative energy （nce） is employed for damage localization in structures. In the second stage, the differential evolution algorithm （DE） is used for damage severity of the structures. In addition, in the second stage, a modification of an available objective function is made for handing the issue of symmetric structures. To verify the effectiveness of the present technique, numerical examples of a 72-bar space truss and a one-span steel portal frame are considered. In addition, the effect of noise on the performance of the identification results is also investigated. The numerical results show that the proposed combination gives good assessment of damage location and extent for multiple structural damage cases.

关键词： damage assessment damage locating vector method (DLV) differential evolution (DE) multiple damagelocation assurance criterion (MDLAC) mode shape error function

Twin reversed arterial perfusion sequence-a rare and dangerous complication form of monochorionic twins:A case report

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World Journal of Clinical Cases 2022年第28期10卷 10214-10219页

作者： nguyen Duy Anh nguyen-Thi Thu Ha nguyen-Thi Sim nguyen Khac Toan Phan-Thi Huyen Thuong nguyen minh Duc Fetal Medicine Center Hanoi Obstetrics and Gynecology HospitalHanoi 100000Vietnam Department of Assisted Reproduction Hanoi Obstetrics and Gynecology HospitalHanoi 100000Vietnam Department of Obstetrics and Gynecology Hanoi University of Medicine and PharmacyHanoi 100000Vietnam Department of Radiology Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam

BACKGROUND Twin reversed arterial perfusion(TRAP) sequence is an extremely rare congenital anomaly in monochorionic(MC) *** condition is characterized by a malformed fetus(acardiac twin) without cardiac activities being perfused by a structurally normal one(pump twin) via an artery-to-artery anastomosis in a reverse *** SUMMARY We described the first case of TRAP to receive laser surgery in *** 26-wk pregnancy was originally misdiagnosed in another hospital as MC twins with single intrauterine fetal *** admission to our center,the diagnosis was amended to a 26-wk TRAP sequence stage *** acardiac twin was 7.5 cm at the longest length,the ratio of the weight of the acardiac twin to the weight of the pump twin was more than 90%,the pump twin showed fetal distress with absent diastolic flow in umbilical artery of pump twin,and the peak systolic velocity in the middle cerebral artery = 1.6 Mo *** performed emergency laser photocoagulation of the acardiac twin’s umbilical *** surgery,we successfully maintained the pregnancy for 8 wk and ended it electively by cesarean section at 34 wk of gestation due to rupture of *** TRAP should be appropriately diagnosed and treated early to avoid complications of the pump *** laser photocoagulation is a new and effective treatment for this condition.

关键词： Twin reversed arterial perfusion Acardiac twin Pump twin Laser Case report

Empirical Analysis on Impact Factors of Green Marketing on Consumer's Willingness to Buy Hygiene Products in Vietnam

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Empirical Analysis on Impact Factors of Green Marketing on C...

作者： nguyen NGOC minh AN 北京化工大学

学位级别：硕士

COVID-19大流行给越南整体经济带来许多变化,特别是个人和家庭卫生行业。随之而来的是环保意识的增强和各种规模的绿色营销活动的爆发。然而,目前并没有研究关注绿色营销对消费者购买卫生用品意愿的影响。因此,论文以越南为研究对象,针... 详细信息

COVID-19大流行给越南整体经济带来许多变化,特别是个人和家庭卫生行业。随之而来的是环保意识的增强和各种规模的绿色营销活动的爆发。然而,目前并没有研究关注绿色营销对消费者购买卫生用品意愿的影响。因此,论文以越南为研究对象,针对绿色营销对消费者购买卫生用品意愿的影响因素展开实证分析。论文主要工作:(1)研究以4P理论为基础,通过调查问卷的形式对350名受访者的购买意愿进行调查。(2)构建逻辑回归模型,对影响购买意愿的人口统计因素进行探究。(3)引入SEM模型,探究绿色促销、绿色产品、绿色价格和绿色场所对卫生用品购买意愿的影响。论文主要结论:(1)350份调查问卷中,回收了342份有效问卷,并通过了相关检验测试。(2)受访者中,性别、收入和认知度是影响购买决策的关键因素。(3)除绿色促销外、绿色产品、绿色价格和绿色场所均对卫生用品的购买行为产生显著的正向影响。然而,作用强度间存在显著差异,回归系数分别为0.255、0.106和0.191。基于主要结论,文章从绿色促销、绿色产品、绿色价格和绿色场所方面提出了一些政策建议,以期为增强绿色营销对消费者购买意愿的影响。

关键词：绿色营销卫生用品购买意

Genetic diversity and conservation of two threatened dipterocarps(Dipterocarpaceae) in southeast Vietnam

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Journal of Forestry Research 2019年第5期30卷 1823-1831页

作者： Dinh-Duy Vu Thi Tuyet-Xuan Bui minh-Duc nguyen Syed Noor Muhammad Shah Dinh-Giap Vu Yi Zhang minh-Tam nguyen Xiao-Hua Huang College of Forestry Northwest A&F UniversityYanglingShaanxi 712100People’s Republic of China Vietnam National Museum of Nature Vietnam Academy of Science and Technology(VAST)18 Hoang Quoc VietCau GiayHanoiVietnam Institute of Ecology and Biological Resource Vietnam Academy of Science and Technology(VAST)18 Hoang Quoc VietCau GiayHanoiVietnam Department of Horticulture Faculty of AgricultureGomal UniversityDera Ismail KhanPakistan Institute of Natural Products Chemistry Vietnam Academy of Science and Technology(VAST)18 Hoang Quoc VietCau GiayHanoiVietnam

Two threatened dipterocarp species,Dipterocarpus costatus and Dipterocarpus alatus are well-known endangered species in lowland forests of southeastern Vietnam,primarily from habitat loss and over-exploitation of their *** develop conservation strategies for these species,we analyzed 242 samples using nine microsatellite markers to determine the genetic variability within and among five populations of *** and three of ***,representing the natural range of dipterocarps in Southeast *** indicated low levels of genetic variability within populations with an average gene diversity of 0.223 for *** and 0.152 for *** of bottleneck tests indicated a reduction in population size of both species(P>0.05).Genetic differentiation among populations was high(FST=0.347 for *** and 0.274 for ***),indicating limited gene flow(Nm=0.662 for *** and 0.47 for ***)and isolated populations related to geographical *** of molecular variance showed high genetic variation within populations(72.92%for *** and 60.81%for ***)compared to among *** analysis and UPGMA tree also indicated the two optimal genetic clusters related to geographical *** results will provide a platform for the conservation,management and restoration of these species.

关键词： Dipterocarps Genetic conservation Gene diversity SSR primers

Fuzzy MCDM Model for Selection of Infectious Waste Management Contractors

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Computers, Materials & Continua 2022年第8期72卷 2191-2202页

作者： nguyen van Thanh nguyen Hoang Hai nguyen Thi Kim Lan Faculty of Commerce Van Lang UniversityHo Chi Minh CityVietnam International Education Institute Van Lang UniversityHo Chi Minh CityVietnam

Healthcare supply chains are under pressure to drive down costs because of digital business,shifting customer needs and new *** waste generated from medical facilities includes medical activities and daily-life activities of patients and their family *** to statistics of the Department of Health EnvironmentalManagement,Vietnam currently has more than 13,500 medical facilities,including hospitals from central to provincial and district levels and private hospitals and medical *** medicine generates about 590 tons of medical waste/day and is estimated to be about 800 tons/*** waste includes ordinary medical waste and hazardous medical waste;in which ordinary medical waste accounts for about 80%–90%,only about 10%–20%is hazardous medical waste including infectious waste and non-infectious hazardous *** is an environmental and occupational health issue that needs attention in developing countries like *** large amounts of medical waste to ensure environmental and personal hygiene,doing so inefficiently creates potential hazards to the environment and increases operating ***,hospitals lack objective criteria and methods to evaluate and select the most optimal infectious medical waste,relying instead on their own subjective assessment and prior ***,the author proposed a fuzzy multicriteria decision making(MCDM)model including Fuzzy Analytic hierarchy process(FAHP)and the Weighted Aggregated Sum-Product Assessment(WASPAS)for infectious medical waste contractors’selection in this *** proposed Fuzzy MCDM method is in-tended to provide a more efficient,accurate method in the selection of infectious medical waste contractors than subjective assessment methods,thus reduce potential risks to *** results of this study can be applied to evaluate and select contractors in other industries.

关键词： MCDM model fuzzy theory fuzzy AHP WASPAS medical waste contractors

Expanded Barro Regression in Studying Convergence Problem

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American Journal of Operations Research 2014年第5期4卷 301-310页

作者： nguyen Khac minh nguyen Khac minh Pham van Khanh National Economics University Hanoi Vietnam Institute of Economics and Corporate Group Hanoi Vietnam

This study develops the approach by minh & Khanh [1] to the classic Barro and Sala-i-Martin method [2], [3] named “expanded Barro regression method”, and applies this approach in analyzing the convergence of provincial per capita GDP in Vietnam over the period of 1991-2007. Different aspects of provincial convergence are considered in this paper. The estimated result on conver-gence from our model is compared to other models.

关键词： Convergence Barro Regression Markov Model Expanded Barro Regression