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能量位涡度平衡方程及其在暴雨诊断分析中的应用

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高原气象 1987年第3期 193-207页

作者：李丁民中国科学院兰州高原大气物理研究所

本文从Ertel广义位涡方程和大气总能量概念出发,导出了一个把能量天气学与动力学相结合的新物理量——能量位涡度。文中给出了相当能量位涡度的概念,导出了二者的简化形式,并对它们的物理意义和天气背景作了讨论。从定义入手,推导了能... 详细信息

本文从Ertel广义位涡方程和大气总能量概念出发,导出了一个把能量天气学与动力学相结合的新物理量——能量位涡度。文中给出了相当能量位涡度的概念,导出了二者的简化形式,并对它们的物理意义和天气背景作了讨论。从定义入手,推导了能量涡度平衡方程,解释了各项的物理意义。在此基础上结合尺度分离方法,对一次暴雨实例作了能量位涡诊断分析和平衡分析,发现暴雨区与能量位涡正中心相对应,与相当能量位涡负中心也对应。最后还讨论了各个因子对能量位涡的贡献,表明能量位涡能够反映出暴雨所必需的动力场和能量背景场条件,并与水汽通量散度结合对暴雨具有诊断意义。

关键词：位涡分析诊断分析低空急流辐合天气尺度急流(气象) 降雨暴雨暴雨区方程

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采用数字图像分析评估银屑病的炎症浸润程度

世界核心医学期刊文摘（皮肤病学分册） 2006年第1期2卷 32-33页

作者： Goedkoop A.Y De rie M.A Teunissen M.B.M 李政霄 Department of Dermatology Academic Medical Center University of Amsterdam P.O. Box 22660 1100 DDAmsterdam Netherlands

Traditionally the evaluation of the cellular infiltrate and protein expression in skin tissue sections is done by manual quantification. However, for reliable evaluation of histology in the development of new anti-psoriatic treatments there is a need for a more time-efficient and reproducible method. To test the use of digital image analysis (DIA) in this situation we compared the assessment of immunohistochemically stained skin sections with themore traditionalmanual quantification (MQ) and semiquantitative analysis (SQA). The number of CD3+T cells and the expression of E-selectin were evaluated in stained paired skin biopsie s from 11 patients with chronic plaque psoriasis before and after initiation of anti-psoriasis therapy. We observed significant correlations between MQ and DIA for the number of T cells (epiderm is: r=0.88, P ≤0.01, dermis r=0.87, P ≤0.01). Both DIA and MQ were equally eff ective in detecting reductions of T-cell numbers in active-treated patients. M Q took 20 h, compared to 6 h for *** also observed significant correlations b etween SQA and DIA for the expression of E-selectin (r=0.88, P ≤0.01), althoug h DIA was more sensitive than SQA to detect (early) changes. SQA took 10 h, comp ared to 4 h for DIA. In conclusion, the quantification of the inflammatory infil trate in psoriatic lesional skin by DIA generated similar results as MQ and SQA in a reliable, reproducible and higher time efficient fashion.

关键词：银屑病炎症浸润数字图像分析内皮细胞选择素活检标本组织切片重复操作半定量分析

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Level of Knowledge Regarding Breast Cancer among Women in the Commune of Parakou in 2021

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Advances in Breast Cancer Research 2023年第1期12卷 1-9页

作者： Luc valère Codjo Brun Yessito Corine Nadège Houehanou-Sonou Nukunté David Lionel Togbenon Marie-Claire Assomption Oloufoudi Balle Pognon Ludwine Ghislaine Fifamè Padonou Falilath Seidou Kabibou Salifou Marie Thérèse Akele Akpo Faculty of Medicine University of Parakou (FM/UP) Parakou Benin National School of Public Health and Epidemiology University of Parakou Parakou Benin Faculty of Health Sciences University of Abomey Calavi (FSS) Cotonou Benin

Background: Women well-informed regarding breast cancer are often most conscious about their breast health and would therefore seek medical attention when detecting the initial symptoms. Objective: This study sought to identify factors associated with a good level of knowledge regarding breast cancer among women in the commune of Parakou in 2021. Method: This was a prospective cross-sectional study with descriptive and analytical purposes, carried out from June 5 to August 5, 2022, among women residing in the first district of the commune of Parakou. A pre-designed questionnaire set up with the Kobotoolbox server was used for data collection through a cluster survey sampling technique. Pearson’s chi-square test was implemented to determine associations between variables. Result: A total of 630 women were included in this study. The prevalence of women well-informed about breast cancer was 21.75% (95% CI = [18.70 - 25.13]). Factors associated with good knowledge regarding breast cancer were age group (p-value value value value Conclusion: Several women remain unaware of breast cancer in the commune of Parakou. A huge effort is still needed to increase the level of coverage of information regarding breast cancer and its prevention methods.

关键词： Knowledge Factors Associated Breast Cancer Women Parakou (Benin)

Helicobacter Pylori Infection: Epidemiological, Clinical and Pathological Aspects in a Digestive Endoscopy Unit and the Pathological Anatomy Service of Parakou in Benin Republic

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Open Journal of Gastroenterology 2023年第7期13卷 225-236页

作者： Khadidjatou Saké Marie Claire Ballè Luc valère Codjo Brun Nonvignon Murielle Somitondji Cossi Angelo Attinsounon Serge Adè Cossi Adébayo Alassani Lionel David Togbenon Comlan Albert Dovonou Marie Thérèse Akélé Akpo Department of Medicine Departmental University Hospital Center of Borgou Parakou Benin Pathological Anatomy and Cytology Service Departmental University Hospital Center of Borgou Parakou Benin Pathological Anatomy and Cytology Service Faculty of Health Sciences National Hospital and University Center Cotonou Benin

Introduction: Helicobacter pylori (Hp) infection is the most common bacterial infection in the world. World Health Organization has classified this bacterium as a Class I carcinogen. The objective of this work is to study the epidemiological, clinical and pathological aspects of Helicobacter pylori infection among adults in a digestive endoscopy unit and the pathological anatomy service of Parakou. Patients and Methods: This was a descriptive and analytical cross-sectional study conducted from January 2020 to September 2020 in the digestive endoscopy unit and pathological anatomy service at the Departmental University Hospital Center of Borgou. Patients aged 18 years and older, who had undergone a gastroscopy with biopsies and who gave their oral consent were included. Three antral biopsies and two fundic biopsies were performed. The search for Hp was done under an optical microscope after staining with hematoxylin eosin. Results: A total of 151 patients were included and 51.66% were infected with Hp. Their average age was 40.63 ± 15.32 years and the sex ratio was 0.9. Epigastric pain was the most reported symptom (71.01%). Endoscopically, the prevalence of erythematous gastropathy was 98.72%. The study of chronic Hp gastritis according to Sydney system had shown signs of activity in 100% of patients with Hp and glandular atrophy in 83.33% of them. Intestinal metaplasia and dysplasia accounted for 24.35% and 29.48% of cases, respectively. Factors associated with Hp infection were: absence of proton pump inhibitor intake prior to examination, absence of handwashing with soap and water before eating, erythematous aspect of gastritis on gastroscopy, absence of intestinal metaplasia of the fundus, active and chronic aspects of gastritis on histology. Conclusion: The frequency of Hp infection in hospitals among adults admitted to the Digestive Endoscopy Unit of Parakou is high. To reduce this prevalence, it will be necessary to act on the factors identified.

关键词： Helicobacter pylori Gastroscopy Pathological Anatomy Parakou Benin Republic

Septic shock 3.0 criteria application in severe COVID-19 patients:An unattended sepsis population with high mortality risk

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World Journal of Critical Care Medicine 2022年第4期11卷 246-254页

作者： JoséPedro Cidade LM Coelho Vasco Costa Rui Morais Patrícia Moniz Luís Morais Pedro Fidalgo António Tralhão Carolina Paulino David Nora Bernardino valério Vítor Mendes Camila Tapadinhas Pedro Povoa Polyvalent Intensive Care Unit Hospital São Francisco XavierCentro Hospitalar Lisboa OcidentalLisboa 1449-005Portugal Polyvalent Intensive Care Unit Hospital Sao Francisco XavierCentro Hospitalar Lisboa OcidentalLisbon 1449-005Portugal Polyvalent Intensive Care Unit Hospital São Francisco XavierCentro Hospitalar Lisboa OcidentalLisbon 1449-005Portugal Polyvalent Intesive Care Unit Hospital São Francisco XavierCentro Hospitalar Lisboa OcidentalLisbon 1449-005Portugal Polyvalent Intens Care Unit NOVA Medical SchoolHospital Sao Francisco XavierCentro Hospitalar Lisboa OcidentalLisbon 1449-005Portugal

BACKGROUND Coronavirus disease 2019(COVID-19)can be associated with life-threatening organ dysfunction due to septic shock,frequently requiring intensive care unit(ICU)admission,respi-ratory and vasopressor ***-fore,clear clinical criteria are pivotal for early recognition of patients more likely to need prompt organ *** most patients with severe COVID-19 meet the Sepsis-3.0 criteria for septic shock,it has been increasingly recognized that hyperlactatemia is frequently absent,possibly leading to an underestimation of illness severity and mortality *** To identify the proportion of severe COVID-19 patients with vasopressor support requirements,with and without hyperlactatemia,and describe their clinical outcomes and mortality METHODS We performed a single-center prospective cohort *** adult patients admitted to the ICU with COVID-19 were included in the analysis and were further divided into three groups:Sepsis group,without both criteria;Vasoplegic Shock group,with persistent hypotension and vasopressor support without hyperlactatemia;and Septic Shock 3.0 group,with both ***-19 was diagnosed using clinical and radiologic criteria with a severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)positive RT-PCR *** 118 patients(mean age 63 years,87%males)were included in the analysis(n=51 Sepsis group,n=26 Vasoplegic Shock group,and n=41 Septic Shock 3.0 group).SOFA score at ICU admission and ICU length of stay were different between the groups(Pval curves were also different(P=0.007).Ventilator-free days and vasopressor-free days were different between the Sepsis vs Vasoplegic Shock and Septic Shock 3.0 groups(both P<0.001),and similar in the last two groups(P=0.128

关键词： COVID-19 Critical care SARS-CoV-2 Septic shock Lactate Sepsis 3.0 criteria

Perceptions and Knowledge about Cervical Cancer among Women Living with HIV in Parakou in 2017

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Open Journal of Epidemiology 2022年第1期12卷 31-49页

作者： Luc Béhanzin Luc valère Codjo Brun Elfried Salanon Marie-Claire Assomption Oloufoudi Balle Pognon Ella Goma-Matsétsé Maurice Agonnoudé David Houéto Thierry Adoukonou Benjamin Hounkpatin Marie Thérèse Akélé Akpo School of Public Health and Epidemiology University of Parakou Parakou Benin Department of Pathological Anatomy Faculty of Medicine University of Parakou Parakou Benin STI Clinic (DIST) Cotonou Community Health Centre 1 Cotonou Benin Obstetrics and Gynecology Service of the Hospital and University Center of the Mother and Child of Lagune (CHUMEL) of Cotonou Cotonou Benin Laboratory of Pathological Anatomy of Cité Houéyiho Faculty of Health Sciences of Cotonou University of Abomey Calavi Godomey Benin

Background: Cervical cancer (CC) is the fourth most common cancer in women and those living with HIV have a six times higher risk of cervical cancer compared to those without. The objective of this study was to assess knowledge and perceptions about cervical cancer in women living with HIV/AIDS (WLWHIV) in the municipality of Parakou in Benin. Methods: This was an analytical cross-sectional study conducted among WLWHIV monitored on antiretrovira (ARV) therapy (ART) centers in Parakou. Study participants were selected by systematic random sampling technique. Data collection took place from September 5, 2017 to November 6, 2017. Log-binomial regression was used to identify associated factors. Results: A total of 167 women were recruited into the study. The median age was 35 years [Interquartile range: 41.50 - 30.00]. More than half of the women had no perception of the cause of CC. Only 12.6% of women believed in the preventive capacity of early screening of CC. Among women, 15.6% knew that it can be prevented, but only 9.6% had heard of HPV and 4.8% knew that HPV vaccination is an effective means of preventing CC. The factors associated with the low level of knowledge were the age at first sexual intercourse (≤24 years), the ART follow-up site (private health structure) and the fact of not having visited a maternity hospital in the last 12 months preceding the survey. Conclusion: The perceptions and knowledge about cervical cancer in the population of women living with HIV and monitored on ART in Parakou were inadequate and disproportionate to their vulnerability to this cancer. In order to avoid a double burden on these women, their ART centers must integrate cervical cancer prevention interventions into ART initiation services.

关键词： Perceptions Knowledge Cervical Cancer Benin HIV

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利用磁性变化测量疲劳寿命的新方法

兵器材料科学与工程 1986年第9期 68-71页

作者： I.S.Choi S.W.Nam K.-T.rie 史洪刚

为了工程构件的安全,必须准确地了解构件的疲劳寿命。从实验便利的角度考虑,直至断裂的循环数N;被用作设计判据。在低周疲劳条件下,断裂前的循环数N;与塑性应变幅△ε;间符合柯芬-曼森（Coffin-Manson）关系:

关键词：导磁率变化法循环数磁导率电动势磁性疲劳寿命疲劳力学性质

日本老龄化背景下的“冬期集住”实践——以北海道西神乐地区为例

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小城镇建设 2018年第4期36卷 53-57页

作者：野村理惠裴妙思北海道大学大学院工学研究院九州大学艺术工学府环境遗产设计专业藤原惠洋研究室

在老龄化特征显著的日本农村地区,如何对持续增加的空置房加以再利用,以及如何对地区内常住的高龄人口施以支援等,已经逐步成为了政策研究的热点课题。本研究针对北海道严寒地区,以"冬期集住"计划的具体实践为例,探讨相关的支援对策。... 详细信息

在老龄化特征显著的日本农村地区,如何对持续增加的空置房加以再利用,以及如何对地区内常住的高龄人口施以支援等,已经逐步成为了政策研究的热点课题。本研究针对北海道严寒地区,以"冬期集住"计划的具体实践为例,探讨相关的支援对策。根据案例分析得知,当地居民可共享冬季"集住"设施,且可根据实际需要分季节实行集合与分散居住。这种居住模式揭示了基于自然环境的集住住宅体系建立的可能性。研究同时也发现,集住与季节性居住在运作中亦存在着诸如运营和维护等方面的问题。

关键词：北海道高龄化农村冬期集住

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促进步行的干预措施：系统性综述

英国医学杂志中文版 2008年第1期11卷 16-25页

作者： David Ogilvie Charles E Foster Helen Rothnie Nick Cavill val Hamilton Claire F Fitzsimons Nanette Mutrie 钱招昕(译) Medical ResearchCouncil Socialand Public HealthSciences Unit MRC fellow British Heart Foundation Health Promotion Research Group University of Oxford Oxford senior resarcher British Heart Foundation Health Promotion Research Group University of Oxford Oxford research associate Deparanent of Sport Culture and the Asts University of Strathclyde Glasgow research associate Deparanent of Sport Culture and the Asts University of Strathclyde Glasgow professor of exer5cise and sport psychology for the on behalf of the Scottish Physical Activity Research Collaboration(SPARColl) Deparanent of Sport Culture and the Asts University of Strathclyde SPARColl project coordinator Development and Alumni Office University of Glasgow Glasgow research assistant 不详

目的评估在个体和群体中促进步行的干预措施的作用。设计系统性综述。数据来源通过搜索25个电子数据库、网站、文献目录和已有的系统性综述，以及通过联系专家，识别出已发表的和未发表的任一语言的报道。综述方法系统性搜索和评价关于... 详细信息

目的评估在个体和群体中促进步行的干预措施的作用。设计系统性综述。数据来源通过搜索25个电子数据库、网站、文献目录和已有的系统性综述，以及通过联系专家，识别出已发表的和未发表的任一语言的报道。综述方法系统性搜索和评价关于任何类型的干预对人们步行的影响的前后对照研究，对干预效果的大小、干预效果在不同社会组群中的分布以及干预对总的体育活动、健身、疾病危险因素、健康状况和体格的影响进行评价。结果研究包括19项随机试验和29项非随机研究。根据人们需求进行的干预乃以大部分久坐的人或者那些有运动动机的人为目标，不论干预的履行是在个体水平（简单建议，支持步程计、使用通讯设备）、家庭水平（个体化营销）或群体水平，都能够激励人们更多地步行，尽管许多此类方法的可持续性、可推广性和临床效果还不确定。应用于工作场所、学校、社区或者地区的干预措施的有效证据通常主要来源于单独的研究或者是亚组分析。结论在目标参与者中，最成功的干预要求要能够在短期内至少使步行量平均每周增加达30-60分钟。从提高人群健康的前景来看，目前许多的研究提供了有效果的证据而不是有效性的证据。然而，促进步行的干预能够大大提高那些最不习惯于运动的人的运动水平。

关键词：系统性综述干预措施个体水平疾病危险因素运动水平干预效果群体水平电子数据库