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Antibacterial HA-coatings on bioresorbable Mg alloy

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Journal of Magnesium and Alloys 2024年第5期12卷 1965-1985页

作者： K.v.Nadaraia D.v.Mashtalyar M.A.Piatkova A.I.Pleshkova I.M.Imshinetskiy M.S.Gerasimenko E.A.Belov v.v.Kumeiko D.N.Kozyrev K.A.Fomenko v.v.Mostovaya B.R.Torpanov A.R.Biktimirov I.S.osmushko S.L.Sinebryukhov S.v.Gnedenkov Institute of Chemistry FEB RAS 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far Eastern Federal University 10 Ajax BayRussky IslandVladivostok 690922Russia A.v.Zhirmunsky National Scientific Center of Marine Biology FEB RAS 17 St.PalchevskogoVladivostok 690041Russia Regional Clinical Dermatovenerological Dispensary 18 V St.GamarnikaVladivostok 690033Russia NMIC“Treatment and Rehabilitation Center” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a calcium-phosphate coating was formed on a Mg-Mn-Ce alloy by the plasma electrolytic oxidation(PEo).The antibiotic vancomycin,widely used in the treatment of infections caused by Staphylococcus aureus(***),was impregnated into the *** with vancomycin showed high bactericidal activity against *** mechanical and electrochemical properties of the formed coatings were studied,as well as in vitro cytotoxicity tests and in vivo tests on mature male rats were *** to SEM,EDS,XRD and XPS data,coatings had a developed morphology and contained hydroxyapatite,which indicates high *** analysis of roughness of coatings without and with vancomycin did not reveal any differences,confirming the high roughness of the *** electrochemical tests,an increase in corrosion resistance by more than two times after the application of PEo coatings was *** to the results of an in vivo study,after 28 days of the implantation of samples with calcium phosphate PEo coating and vancomycin,no signs of inflammation were observed,while an inflammatory reaction developed in the area of implantation of bare alloy,followed by *** release tests from the coatings show a sharp decrease in the concentration of the released antibiotic on day 7 and then a gradual decrease until day *** the experiment,no significant deviations in the condition and behavior of the animals were observed;clinical tests did not reveal a systemic toxic reaction.

关键词： Bioactive coatings Biocompatibility Mg alloy Plasma electrolytic oxidation Hydroxyapatite vancomycin

Conformally symmetric wormhole solutions supported by non-commutative geometry in f(Q,T)gravity

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Communications in Theoretical Physics 2024年第2期76卷 111-124页

作者： Chaitra Chooda Chalavadi v venkatesha N S Kavya S v Divya Rashmi Department of P.G.Studies and Research in Mathematics Kuvempu UniversityShankaraghattaShivamogga 577451KarnatakaIndia Department of Mathematics Vidyavardhaka College of EngineeringMysuru—570002India

This paper investigates wormhole solutions within the framework of extended symmetric teleparallel gravity,incorporating non-commutative geometry,and conformal *** achieve this,we examine the linear wormhole model with anisotropic fluid under Gaussian and Lorentzian *** primary objective is to derive wormhole solutions while considering the influence of the shape function on model parameters under Gaussian and Lorentzian *** resulting shape function satisfies all the necessary conditions for a traversable ***,we analyze the characteristics of the energy conditions and provide a detailed graphical discussion of the matter contents via energy ***,we explore the effect of anisotropy under Gaussian and Lorentzian ***,we present our conclusions based on the obtained results.

关键词： traversable wormhole f(Q T)gravity energy conditions non-commutative geometry conformal motion

Boosting propane dehydrogenation by gallium hydride species formed in situ

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Science China Chemistry 2024年第6期67卷 1753-1755页

作者： Evgenii v.Kondratenko Leibniz-Institut für Katalyse e.v. Albert-Einstein-Str.29aRostock18059Germany

An inspiring paper recently published in Nature Chemistry[1]by the group of *** Gong at Tianjin University is the motivation for this highlight *** reported results show that the understanding of reaction-induced restructuring of heterogeneous catalysts is of great importance for their targeted development because usually unstable compounds can be formed and stabilized under reaction conditions.

关键词： conditions hydride stabilized

Kuedinskie Kluchiki, a Unique Middle Permian Biota Locality as a Key-point for Reconstruction of Late Paleozoic Terrestrial Ecosystems of the Urals, Russia

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 850-866页

作者： Serge v.NAUGoLNYKH Geological Institute of Russian Academy of Sciences Pyzhevsky per.7119017 MoscowRussia

Field work focused on the Kuedinskie Kluchiki locality, Perm region, Urals, Russia, which contains a rich assemblage of diverse fossil organisms including higher plants(equisetophytes, pteridosperms, ginkgophytes, conifers, vojnovskyans) represented by stems, leaves and reproductive organs;invertebrates(mollusks, arthropods), and tetrapods(temnospondyl amphibians, seymouriamorphs, cotylosaurs, synapsids, diapsids), as well as bony fishes. General characteristics of the taxonomical composition of the Kuedinskie Kluchiki locality are given. A new peltaspermalean pteridosperm taxon, Compsopteris longipinnata sp. nov., and a voltzialean conifer Archaeovoltzia kuedensis sp. nov. are described. General considerations on the paleoecologic and paleogeographic conditions of the Kuedinskie Kluchiki locality origin are given.

关键词： paleobotany paleoecology taxonomy Lagerst?tten new taxa peltasperms conifers Wordian Cis-Urals

Detailed seismic zoning of the East Kazakhstan region in the Republic of Kazakhstan

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Geodesy and Geodynamics 2024年第2期15卷 156-165页

作者： Natalya v.Silacheva N.P.Stepanenko o.K.Kurilova A.D.Kudabayeva A.T.Danabayeva Institute of Seismology Ministry of Emergency SituationsAlmaty 050060Kazakhstan

Kazakhstan is currently drafting new construction regulations that comply with the major provisions of the *** regulations are created on the basis of seismic zoning maps of various degrees of detail,developed by our Institute of Seismology using a new methodological approach for *** article is about creating the first normative map of the Detailed Seismic Zoning on a probabilistic foundation for the Republic of Kazakhstan’s East Kazakhstan *** carried out the probabilistic assessment of seismic hazard using a methodology consistent with the main provisions of Eurocode 8and updated compared with that used in developing maps of Kazakhstan’s General Seismic Zoning and seismic microzoning of *** most thorough and current data accessible for the area under consideration were combined with contemporary analytical *** have been done to not only the databases being used but also the way seismic sources were shown,including active faults *** a scale of 1:1000000,precise seismic zoning maps of the East Kazakhstan region were created for two probabilities of exceedance:10%and 2%in 50 years in terms of peak ground accelerations and macroseismic *** obtained seismic hazard distribution is generally consistent with the General Seismic Zoning of Kazakhstan’s previous ***,because active faults were included and a thoroughly revised catalog was used,there are more pronounced zones of increased danger along the fault in the western part of the *** the west of the territory,acceleration values also increased due to a more accurate consideration of seismotectonic *** maps are the basis for developing new state building regulations of the Republic of Kazakhstan.

关键词： Probabilistic seismic hazard assessment Detailed seismic zoning Peak ground acceleration Microseismical intensity

Parasites of the liver:A global problem?

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World Journal of Gastroenterology 2024年第30期30卷 3554-3559页

作者： vladislav v Tsukanov Alexander v vasyutin Julia L Tonkikh Clinical Department of the Digestive System Pathology of Adults and Children Federal Research Center“Krasnoyarsk Science Center”of the Siberian Branch of the Russian Academy of SciencesScientific Research Institute of Medical Problems of the NorthKrasnoyarsk 660022Russia

Parasitic liver diseases can be caused by trematodes,cestodes,nematodes,and *** pathology is significant because millions of people in different parts of the world have liver parasites,which can manifest themselves in the development of inflammation,liver cysts,cholecystitis,cholelithiasis,pancreatitis and liver cirrhosis that are often threatening their *** International Agency for Research on Cancer considers three species of trematodes,Schistosoma haematobium,opisthorchis viverrini and Clonorchis sinensis,to be *** modern examination methods,in some cases including extensive screening of large populations,are required for diagnosing liver *** of parasitic liver diseases is differentiated and can involve a combination of surgical and therapeutic *** is no doubt that the clinical and epidemiological scale allows one to regard parasitic liver diseases as a global healthcare problem.

关键词： Liver Parasites Epidemiology Diagnosis Clinics Treatment Echinococcosis opisthorchiasis Fascioliasis Schistosomiasis

MicroRNAs as potential biomarkers for diagnosis of schizophrenia and influence of antipsychotic treatment

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Neural Regeneration Research 2024年第7期19卷 1523-1531页

作者： Bridget Martinez Philip v.Peplow Department of Pharmacology University of Nevada-RenoRenoNVUSA Department of Medicine University of Nevada-RenoRenoNVUSA Department of Anatomy University of OtagoDunedinNew Zealand

Chara cterized by positive symptoms(such as changes in behavior or thoughts,including delusions and hallu cinations),negative symptoms(such as apathy,anhedonia,and social withdrawal),and cognitive impairments,schizophrenia is a chro nic,severe,and disabling mental disorder with late adolescence or early adulthood onset,Antipsychotics are the most commonly used drugs to treat schizophrenia,but those currently in use do not fully reverse all three types of symptoms characte rizing this *** is frequently misdiagnosed,resulting in a delay of or inappropriate *** expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of *** recent studies reviewed included microRNA profiling in blood-and urine-based materials and nervous tissue mate *** the studies that had validated the preliminary findings,potential candidate biomarkers for schizophrenia in adults could be miR-22-3p,-30e-5p,-92a-3p,-148b-5p,-181a-3p,-181a-5p,-181b-5p,-199 b-5p,-137 in whole blood,and miR-130b,-193a-3p in blood *** treatment of schizophrenia patients was found to modulate the expression of certain microRNAs including miR-130b,-193a-3p,-132,-195,-30e,-432 in blood *** studies are warranted with adolescents and young adults having schizophrenia and consideration should be given to using animal models of the disorder to investigate the effect of suppressing or overexpressing specific microRNAs.

关键词： antipsychotics biomarkers blood exosomes blood plasma brain tissue exosomes brain tissues leukocytes microRNAs neural stem cells olfactory neuroepithelium schizophrenia whole blood

MicroRNAs as potential biomarkers for diagnosis of attention deficit hyperactivity disorder

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Neural Regeneration Research 2024年第3期19卷 557-562页

作者： Bridget Martinez Philip v.Peplow Department of Pharmacology University of Nevada-RenoRenoUSA Department of Medicine University of Nevada-RenoRenoUSA Department of Anatomy University of OtagoDunedinNew Zealand

Inappropriate levels of hyperactivity,impulsivity,and inattention characterize attention deficit hyperactivity disorder,a common childhood-onset neuropsychiatric *** cognitive function and learning ability of children with attention deficit hyperactivity disorder are affected,and these symptoms may persist to adulthood if they are not *** diagnosis of attention deficit hyperactivity disorder is only based on symptoms and objective tests for attention deficit hyperactivity disorder are *** for attention deficit hyperactivity disorder in children include medications,behavior therapy,counseling,and education services which can relieve many of the symptoms of attention deficit hyperactivity disorder but cannot cure *** is a need for a molecular biomarker to distinguish attention deficit hyperactivity disorder from healthy subjects and other neurological conditions,which would allow for an earlier and more accurate diagnosis and appropriate treatment to be *** expression of microRNAs is connected to brain development and disease and could provide novel biomarkers for the diagnosis and prognosis of attention deficit hyperactivity *** recent studies reviewed had performed microRNA profiling in whole blood,white blood cells,blood plasma,and blood serum of children with attention deficit hyperactivity disorder.A large number of microRNAs were dysregulated when compared to healthy controls and with some overlap between individual *** the studies that had included a validation set of patients and controls,potential candidate biomarkers for attention deficit hyperactivity disorder in children could be miR-140-3p,let-7g-5p,-30e-5p,-223-3p,-142-5p,-486-5p,-151a-3p,-151a-5p,and-126-5p in total white blood cells,and miR-4516,-6090,-4763-3p,-4281,-4466,-101-3p,-130a-3p,-138-5p,-195-5p,and-106b-5p in blood *** studies are warranted with children and adults with attention deficit hyperactivity disorder,and

关键词： adults attention deficit hyperactivity disorder biomarkers blood plasma blood serum children microRNA total white blood cells whole blood

Effect of the Coulomb and dielectric forces on the onset of Rayleigh-Bénard convection

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Acta Mechanica Sinica 2024年第6期40卷 64-77页

作者： Zhonglin Du Pedro A.vázquez Jian Wu School of Energy Science and Engineering Harbin Institute of TechnologyHarbin150001China Heilongjiang Key Laboratory of Micro-and Nano-scale Fluid Flow and Heat Transfer Harbin150001China Departamento de Física Aplicada III ETSIIUniversidad de SevillaSevilla41092Spain

In this paper,the effect of Coulomb and dielectric forces on the onset of Rayleigh-Bénard convection(RBC)in a dielectric liquid layer contained between two parallel electrode plates has been numerically *** different operating conditions have been considered in electrohydrodynamic(EHD)conduction:ohmic and saturation,and variations in the physical properties of the dielectric fluid with *** electric equations and the state equations based on the Boussinesq approximation are integrated in the framework of openFoAM buoyantBoussinesqPimpleFoam *** results show that in the ohmic regime,the combined effect of Coulomb and dielectric forces promotes the onset of RBC flow,while in the saturation state,the inhibition of RBC flow by Coulomb force is more *** value of the critical Rayleigh number Ra decreases with increasing electric Reynolds number ReE in the ohmic regime,whereas in the saturation state,the critical Ra increases with increasing *** the saturation regime,the flow field always has a steady flow in the range of parameters ***,the onset of the RBC flow promoted by the dielectric force is more pronounced in the ohmic *** to the presence of the dielectric force,the flow field exhibits periodic oscillatory flow at low electric Reynolds numbers for the range of parameters considered.

关键词： EHD conduction Dielectric force Rayleigh-Bénard convection openFoAM