检索结果-南通市图书馆

Chebyshev polynomial-based Ritz method for thermal buckling and free vibration behaviors of metal foam beams

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 891-910页

作者： N.D.NGUYEN t.N.NGUYEN Faculty of Civil Engineering Ho Chi Minh City University of Technology and EducationHo Chi Minh City 71309Viet Nam Faculty of Engineering and technology Kien Giang UniversityChau Thanh 92000Viet Nam

this study presents the Chebyshev polynomials-based Ritz method to examine the thermal buckling and free vibration characteristics of metal foam *** analyses include three models for porosity distribution and two scenarios for thermal *** material properties are assessed under two conditions,i.e.,temperature dependence and temperature *** theoretical framework for the beams is based on the higher-order shear deformation theory,which incorporates shear deformations with higher-order *** governing equations are established from the Lagrange equations,and the beam displacement fields are approximated by the Chebyshev *** simulations are performed to evaluate the effects of thermal load,slenderness,boundary condition(BC),and porosity distribution on the buckling and vibration behaviors of metal foam *** findings highlight the significant influence of temperature-dependent(tD)material properties on metal foam beams'buckling and vibration responses.

关键词： Ritz method Chebyshev function buckling vibration metal foam beam higher-order beam theory(HOBt)

Is Deep time Geology Scientific?

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第2期35卷 700-703页

作者： t.Mark Harrison Department of Earth Planetary and Space SciencesUniversity of CaliforniaLos Angeles90095USA

We all know what car mechanics *** maintain and repair our automobiles according to established engineering *** all know what physicians *** maintain and repair our bodies according to established medical *** what is it that I do as a scientist?Indeed,am I a scientist?the answer to these questions depends on what we meant by“science”.

关键词： maintain Deep repair

Unsteady MHD Casson Nanofluid Flow Past an Exponentially Accelerated vertical Plate:An Analytical Strategy

在线全文

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第7期140卷 431-460页

作者： t.Aghalya R.tamizharasi Department of Mathematics School of Advanced SciencesVellore Institute of TechnologyVelloreTamilnadu632014India

In this study,the characteristics of heat transfer on an unsteady magnetohydrodynamic(MHD)Casson nanofluid over an exponentially accelerated vertical porous plate with rotating effects were *** flow was driven by the combined effects of the magnetic field,heat radiation,heat source/sink and chemical *** oxide(CuO)and titanium oxide(tiO2)are acknowledged as nanoparticle *** nondimensional governing equations were subjected to the Laplace transformation technique to derive closed-form *** representations are provided to analyze how changes in physical parameters,such as the magnetic field,heat radiation,heat source/sink and chemical reaction,affect the velocity,temperature and concentration *** computed values of skin friction,heat and mass transfer rates at the surface were tabulated for various sets of input *** is perceived that there is a drop in temperature due to the rise in the heat source/sink and the Prandtl *** should be noted that a boost in the thermal radiation parameter prompts an increase in *** increase in the Prandtl number,heat source/sink parameter,time and a decrease in the thermal radiation parameter result in an increase in theNusselt *** computed values of the skin friction,heat andmass transfer rates at the surface were tabulated for various values of the flow *** present results were compared with those of previously published studies andwere found to be in excellent *** research has practical applications in areas such as drug delivery,thermal medicine and cancer treatment.

关键词： thermal radiation radiative flux nanofluid copper oxide titanium oxide accelerated plate

Eliciting CD4-mimicking broadly neutralizing antibodies:new avenues towards the rational design of an HIv vaccine

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal transduction and targeted therapy 2024年第3期9卷 836-838页

作者： Frauke Muecksch Oliver t.Fackler Department of Infectious Diseases Heidelberg UniversityMedical Faculty HeidelbergVirologyCenter for Integrative Infectious Disease Research(CIID)HeidelbergGermany Chica and Heinz Schaller(CHS)Research Group Department of Infectious DiseasesVirologyUniversity Hospital HeidelbergHeidelbergGermany Department of Infectious Diseases Heidelberg UniversityMedical Faculty HeidelbergIntegrative VirologyCenter for Integrative Infectious Disease Research(CIID)HeidelbergGermany German Centre for Infection Research(DZIF) Partner Site HeidelbergHeidelbergGermany

In a study recently published in Cell,Saunders et *** that a new anti-HIv vaccine triggers antibody responses resembling CD4-binding site broadly neutralizing antibody precursors in rhesus macaques.1 this study provid... 详细信息

关键词： al. vaccine rational

Recent Advances in Catalytic Carbonylation Reactions in Alternative Reaction Media

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2024年第4期42卷 406-429页

作者： Csaba Árvai László t.Mika Department of Chemical and Environmental Process Engineering Faculty of Chemical Technology and BiotechnologyBudapest University of Technology and EconomicsMűegyetem rkp.3H-1111 BudapestHungary

Since the discovery of the hydroformylation(oxo-synthesis or Roelen reaction)and the Reppe-reaction,the transition metal-catalyzed carbonylation reactions,providing versatile,facile,and even atom-economic methods for the selective incorporation of C=O functionality to various skeletons,have gained tremendous importance in synthetic organic chemistry from laboratories to industrial *** carbonylation of carbon-carbon multiple bonds,aromatic halides,triflates,etc.,in the presence of various nucleophiles has led the way to produce aldehydes,carboxylic acids,esters,amides,etc.,in the fine chemical ***,these protocols usually proceed in conventional,fossil-based,and usually toxic reaction ***,several attempts have been directed to developing efficient carbonylation methods in alternative,less harmful,non-fossil-based and even in renewable reaction *** this review,we overview the recent applications of alternative solvents such as water,biomass-based alcohols,γ-valerolactone(GvL),2-methyltetrahydrofuran(2-MetHF),ionic liquids(ILs),deep eutectic solvents(DES),alkyl levulinates,limonene,α-pinene,and dimethyl carbonate as well as fluorous media to improve efficiency,safety and environmentally benign nature of carbonylation protocols.

关键词： Carbonylation Catalysis Solvents Green chemistry Carbon monoxide transition metals Homogeneous catalysis Palladium

A detailed comparison of the composition of(RE)-Ba-Cu-O-Ag bulk superconductors

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Superconductivity 2024年第1期9卷 87-94页

作者： J.v.J.Congreve Y.Shi A.R.Dennis H.Druiff N.C.tutt D.A.Cardwell J.H.Durrell Department of Engineering University of CambridgeCambridgeUK

the homogeneity of the microstructure and composition are critical in determining the properties of rare earthbarium‐cuprate,single grain bulk superconductors[(RE)BCO].the magnitude of the trapped magnetic field achieveable in these technologically important materials,in particular,is influenced heavily by the size and distribution of(RE)_(2)BaCuO_(x)(RE‐211)flux pinning inclusions in the bulk microstructure,whereas the size and distribution of silver agglomerates present within the bulk superconducting matrix correlate directly with improved mechanical *** careful engineering,these materials have significant potential for application in range of devices related to energy storage,medicine,electro‐magnetic machinery and microelectronic *** of(RE)BCO bulk superconductors typically involves heating a powder compact above its peritectic decomposition temperature followed by slow cooling to facilitate the growth of a single ***(RE)BCO composition has a different peritectic temperature and growth rate,which,therefore,necessitates different requirements in the heating *** fabrication temperature and growth rate,for example,may have an effect on the RE‐211 and silver distribution,which may,in turn,affect the superconducting properties of the resulting single *** this work we compare the distributions of silver and RE‐211 in the single grain microstructures of YBCOAg,GdBCO‐Ag,EuBCO‐Ag and SmBCO‐Ag bulk superconductors using optical microscopy,scanning electron microscopy and energy dispersive X‐ray *** observe that the distributions are very similar along both the a/b‐axis and c‐axis of these *** suggests that factors other than the maximum temperature used to achieve peritectic decomposition and the rate of single grain growth are particularly influential in determining the properties of the as‐processed samples in the top seeded melt growth *** observation demonstrates there is freedom to us

关键词： YBCO‐Ag GdBCO‐Ag SmBCO‐Ag EuBCO‐Ag Composition Bulk superconductor

EP Aquarii:A New Picture of the Circumstellar Envelope

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第3期24卷 83-105页

作者： Pham t.Nhung Do t.Hoai Pierre Darriulat Pham tuan-Anh Pham N.Diep Nguyen B.Ngoc tran t.thai Department of Astrophysics Vietnam National Space CenterVietnam Academy of Science and Technology18Hoang Quoc VietNghia DoCau GiayHa Noivietnam

New analyses of earlier ALMA observations of oxygen-rich AGB star EP Aquarii are presented,which complete a previously published analysis and offer a different interpretation of the morpho-kinematics of the circumstellar *** birth of the equatorial density enhancement(EDE)is shown to occur very close to the star where evidence for rotation has been *** to the star and where outflows have been observed:their interaction with the gas of the nascent EDE is seen to play an important role in the development of the wind and the evolution of its radial velocity from 8 to 10 km s^(-1) on the polar symmetry axis to~2 km s^(-1) at the *** implies complex morpho-kinematics:making reliable interpretations with reasonable confidence is *** particular,it questions an earlier interpretation implying the presence of a white dwarf companion orbiting the star at an angular distance of -0″4 from its *** proposes instead an interpretation in terms of a standard mass ejection associated with a shock wave leaving a void of emission in its *** Doppler velocity wings are seen to consist of two components,the upper velocity end of the global wind,reaching above±12 km s^(-1),and an effective line broadening,confined within 200 mas from the center of the star,reaching above±20 km s^(-1) and interpreted as caused by the pattern of shock waves resulting from the interaction between stellar pulsation and convective cell partition.

关键词： stars AGB and post-AGB-(stars) circumstellar matter-radio lines stars

Circulating microRNA expression and nonalcoholic fatty liver disease in adolescents with severe obesity

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第4期30卷 332-345页

作者： Yi-Jie Li Brittney O Baumert Nikos Stratakis Jesse A Goodrich Hao-tian Wu Jing-Xuan He Yin-Qi Zhao Max t Aung Hong-Xu Wang Sandrah P Eckel Douglas I Walker Damaskini valvi Michele A La Merrill Justin R Ryder thomas H Inge todd Jenkins Stephanie Sisley Rohit Kohli Stavra A Xanthakos Andrea A Baccarelli Rob McConnell David v Conti Lida Chatzi Department of Population and Public Health Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90032United States Barcelona Institute of Global Health Barcelona Institute of Global HealthBarcelona 08036Spain Department of Environmental Health Sciences Mailman School of Public HealthColumbia UniversityNew YorkNY 10032United States Gangarosa Department of Environmental Health Rollins School of Public HealthEmory UniversityAtlantaGA 30329United States Department of Environmental Medicine and Public Health Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Department of Environmental toxicology University of CaliforniaDavisCA 95616United States Department of Surgery Lurie Children’s Hospital of ChicagoChicagoIL 60611United States Northwestern University Feinberg School of Medicine Northwestern UniversityChicagoIL 60611United States Division of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States Department of Pediatrics University of Cincinnati College of MedicineCincinnatiOH 45229United States Department of Pediatrics Children’s Nutrition Research Center USDA/ARSBaylor College of MedicineHoustonTX 77030United States Department of Gastroenterology Children’s Hospital Los AngelesLos AngelesCA 90027United States Division of Gastroenterology Hepatology and NutritionCincinnati Children's Hospital Medical CenterCincinnatiOH 45229United States

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases in children and *** ranges in severity from isolated hepatic steatosis to nonalcoholic steatohepatitis(NASH),wherein hepatocellular inflammation and/or fibrosis coexist with *** microRNA(miRNA)levels have been suggested to be altered in NAFLD,but the extent to which miRNA are related to NAFLD features remains *** analysis tested the hypothesis that plasma miRNAs are significantly associated with histological features of NAFLD in *** to investigate the relationship between plasma miRNA expression and NAFLD features among adolescents with *** this study included 81 adolescents diagnosed with NAFLD and 54 adolescents without NAFLD from the teen-Longitudinal Assessment of Bariatric Surgery ***-operative core liver biopsies were collected from participants and used to characterize histological features of *** samples were collected during surgery for miRNA profiling.A total of 843 plasma miRNAs were profiled using the HtG EdgeSeq *** examined associations of plasma miRNAs and NAFLD features using logistic regression after adjusting for age,sex,race,and other key *** Pathways Analysis was used to identify biological functions of miRNAs that were associated with multiple histological features of *** We identified 16 upregulated plasma miRNAs,including miR-193a-5p and miR-193b-5p,and 22 downregulated plasma miRNAs,including miR-1282 and miR-6734-5p,in adolescents with ***,52,16,15,and 9 plasma miRNAs were associated with NASH,fibrosis,ballooning degeneration,and lobular inflammation,***,16 miRNAs were associated with two or more histological features of *** those miRNAs,miR-411-5p was downregulated in NASH,ballooning,and fibrosis,while miR-122-5p,miR-1343-5p,miR-193a-5p,miR-193b-5p,and miR-7845-5p were consistently and posi

关键词： MicroRNA Nonalcoholic fatty liver disease Non-alcoholic steatohepatitis Liver fibrosis Lobular inflammation Ballooning degeneration

RARRES2's impact on lipid metabolism in triplenegative breast cancer:a pathway to brain metastasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Military Medical Research 2024年第2期11卷 311-312页

作者： Quazi t.H.Shubhra Institute of Chemistry University of Silesia in Katowice41‑500 ChorzowPoland Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhan 430060China

Breast cancer brain metastasis(BCBrM)is a crucial and hard area of research which guarantees an urgent need to understand the underlying molecular mechanisms.A recent study by Li et al.[1]published in Military Medical Research investigated the role of retinoic acid receptor responder 2(RARRES2)in regulating lipid metabolism in BCBrM,highlighting the clinical relevance of alterations in lipid metabolites,such as phosphatidylcholine(PC)and triacylglycerols(tAGs),by RARRES2 through the modulation of phosphatase and tensin homologue(PtEN)-mammalian target of rapamycin(mtOR)-sterol regulatory element-binding protein 1(SREBP1)signaling *** commentary aims to elaborate on the key findings and their relevance to the field.

关键词： Retinoic acid receptor responder 2(RARRES2) Lipid metabolism Cancer PtEN-mtOR-SREBP1 signaling Metabolic reprogramming Brain metastasis