检索结果-南通市图书馆

Signal transduction and targeted therapy 2024年第7期9卷 2848-2850页

作者： Qiang Cai Yihao tian Quazi t.H.Shubhra Department of Neurosurgery Renmin Hospital of Wuhan UniversityWuhanChina Department of Human Anatomy and Histology and Embryology School of Basic Medical SciencesWuhan UniversityWuhanChina Institute of Chemistry University of Silesia in KatowiceSzkolna 9KatowicePoland

In a recent study published in Nature Nanotechnology,Li et *** the synthesis of a novel photosensitizer with unique aggregation-induced emission(AIE)characteristics.1 they microencapsulated this photosensitizer inside engineered nanoparticles(NPs)coated with pre-activated macrophage cell membranes(CMs),an innovative approach marking a significant leap in nanomedicine by offering a pathway to potent tuberculosis(tB)treatments that bypass antibiotic resistance with unparalleled precision.

关键词： tuberculosis macrophage aggregation

QCD sum rule study of J^(P)=1^(±)exotic states with two heavy quarks in the molecular picture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第6期48卷 31-37页

作者： t.M.Aliev S.Bilmis M.Savcı Department of Physics Middle East Technical UniversityAnkara06800Turkey tUBItAK ULAKBIM Ankara06510Turkey

In this study,the spectroscopic parameters of exotic molecular states composed of mesons containing two heavy quarks(scalar-axial and pseudoscalar-axial meson combinations)are investigated within the QCD sum *** findings reveal that molecular states containing charm quarks do not form bound states,whereas states with b-quarks can form exotic molecular *** observation has significant implications for understanding the structure of these exotic states.

关键词： QCD sum rules exotic mesons molecular states

Multi-layer perceptron-based data-driven multiscale modelling of granular materials with a novel Frobenius norm-based internal variable

在线全文

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2198-2218页

作者： Mengqi Wang Y.t.Feng Shaoheng Guan tongming Qu Zienkiewicz Centre for Computational Engineering Faculty of Science and EngineeringSwansea UniversitySwanseaWalesSA18EPUK Institute of theoretical and Computational Physics Graz University of TechnologyGraz8010Austria Department of Civil and Environmental Engineering Hong Kong University of Science and TechnologyClearwater BayKowloonHong KongChina

One objective of developing machine learning(ML)-based material models is to integrate them with well-established numerical methods to solve boundary value problems(BvPs).In the family of ML models,recurrent neural networks(RNNs)have been extensively applied to capture history-dependent constitutive responses of granular materials,but these multiple-step-based neural networks are neither sufficiently efficient nor aligned with the standard finite element method(FEM).Single-step-based neural networks like the multi-layer perceptron(MLP)are an alternative to bypass the above issues but have to introduce some internal variables to encode complex loading *** this work,one novel Frobenius norm-based internal variable,together with the Fourier layer and residual architectureenhanced MLP model,is crafted to replicate the history-dependent constitutive features of representative volume element(RvE)for granular *** obtained ML models are then seamlessly embedded into the FEM to solve the BvP of a biaxial compression case and a rigid strip footing *** obtained solutions are comparable to results from the FEM-DEM multiscale modelling but achieve significantly improved *** results demonstrate the applicability of the proposed internal variable in enabling MLP to capture highly nonlinear constitutive responses of granular materials.

关键词： Granular materials History-dependence Multi-layer perceptron(MLP) Discrete element method FEM-DEM Machine learning

Enhanced and asymmetric signatures of hybridization at climatic margins: Evidence from closely related dioecious fig species

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Diversity 2024年第2期46卷 181-193页

作者： Jian-Feng Huang Clive t.Darwell Yan-Qiong Peng CAS Key Laboratory of tropical Forest Ecology Xishuangbanna Tropical Botanical GardenChinese Academy of SciencesMengla 666303China National Center for Genetic Engineering and Biotechnology(BIOtEC) 113 Thailand Science ParkPhahonyothin RoadKhlong NuengKhlong LuangPathum Thani 12120Thailand

Hybridization plays a significant role in biological evolution. However, it is not clear whether ecological contingency differentially influences likelihood of hybridization, particularly at ecological margins where parental species may exhibit reduced fitnesses. Moreover, it is unknown whether future ecosystem change will increase the prevalence of hybridization. Ficus heterostyla and F. squamosa are closely related species co-distributed from southern thailand to southwest China where hybridization, yielding viable seeds, has been documented. As a robust test of ecological factors driving hybridization, we investigated spatial hybridization signatures based on nuclear microsatellites from extensive population sampling across a widespread contact range. Both species showed high population differentiation and strong patterns of isolation by distance. Admixture estimates exposed asymmetric interspecific gene *** of hybridization increase significantly towards higher latitude zones, peaking at the northern climatic margins. Geographic variation in reproductive phenology combined with ecologically challenging marginal habitats may promote this phenomenon. Our work is a first systematic evaluation of such patterns in a comprehensive, latitudinally-based clinal context, and indicates that tendency to hybridize appears strongly influenced by environmental conditions. Moreover, that future climate change scenarios will likely alter and possibly augment cases of hybridization at ecosystem scales.

关键词： Hybridization Heterospecific visitation Fig Pollinator wasp Asymmetric gene flow

Analysis of strong decays of SU(3)partners ofΩ(2012)baryon

在线全文

学校读者我要写书评

暂无评论

Chinese Physics C 2024年第8期48卷 34-41页

作者： t.M.Aliev S.Bilmis M.Savci Department of Physics Middle East Technical UniversityAnkara 06800Turkey tUBItAK ULAKBIM Ankara 06510Turkey

We estimate the coupling constants and decay widths of the SU(3)partners of theΩ(2012)hyperon,as discovered by the BELLE Collaboration,using the distribution amplitudes of the octet baryons within the light cone sum rules *** study includes a comparison of the obtained results for the relevant decay widths with those derived within the framework of the flavor SU(3)*** observe a good agreement between the predictions of both ***,our result on the decay width ofΩ→ΞK is compatible with the existing experimental result within the uncertainties of the model *** results can provide helpful insights for determining the nature of the SU(3)partners of theΩ(2012)baryon.

关键词： coupling constants light cone sum rule hyperon

the Planck theory of Sonoluminescence

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 1998年第4期8卷 3-5页

作者： t.v.Prevenslik 2E Greenery Court China Discovery Bay Hong Kong

Sonolummescence (SL) may be explained by a theory, called the Planck theory of SL that treats she bubbles as miniature collapsing cavities. During bubble collapse, the Planck energy intrinsic to the cavity dimensions is converted to microwave photons that accumulate in the bubble wall molecules. Photons are emitted from the bubble wall molecules as the Planck energy accumulates to electronic levels.

关键词： Sonolluninescence Planck theory IRaser.

Assessment of challenges and strategies for driving energy transitions in emerging markets:A socio-technological systems perspective

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Energy Geoscience 2024年第2期5卷 81-100页

作者： Nelson S.Chipangamate Glen t.Nwaila Wits Mining Institute University of the Witwatersrand1 Jan Smuts Ave.Johannesburg2000South Africa School of Geosciences University of the WitwatersrandPrivate Bag 3Wits2050South Africa

the pursuit of improved quality of life standards has significantly influenced the contemporary mining model in the 21st *** era is witnessing an unprecedented transformation driven by pressing concerns related to sustainability,climate change,the just energy transition,dynamic operating environments,and complex social *** transitions present both opportunities and *** aim of this study is to provide an extensive literature review on energy transition to identify the challenges and strategies associated with navigating transformations in energy *** these transformations is particularly critical in the face of the severe consequences of global warming,where an accelerated energy transition is viewed as a universal *** a socio-technological systems perspective,specifically through the application of Actor Network theory(ANt),this research provides a theoretical foundation while categorising challenges into five distinct domains and outlining strategies across these different *** insights are specifically tailored for emerging market countries to effectively navigate energy transition while fostering the development of resilient ***,our findings highlight that energy transition encompasses more than a mere technological shift;it entails fundamental changes in various systemic socio-economic *** focusing on the role of social structures in transitions,this study makes a significant and innovative contribution to ANt,which has historically been criticised for its limited acknowledgement of social ***,we propose an emerging market energy transition framework,which not only addresses technological aspects,but also integrates social *** framework paves the way for future research and exploration of energy transition *** outcomes of this study offer valuable insights to policymakers,researchers,and practitioners engaged in t

关键词： Actor network theory Energy transition Social innovation technology Actor inclusive policy

A test of the species confidence hypothesis in dusky damselfish

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2024年第1期70卷 79-86页

作者： Elle Overs Sydney Stump Isabel Severino Daniel t.Blumstein Department of Ecology and Evolutionary Biology University of CaliforniaLos AngelesCA 90095-1606USA

visual cues are important in both interspecific and intraspecific *** species confidence hypothesis proposes that animals are more attracted to conspecific colors and repelled by colors,not on their *** on terrestrial lizards and birds have tested the species confidence hypothesis and shown that conspecific colors elicit reduced antipredator *** date,the species confidence hypothesis has not been tested in the marine environment,specifically on coral reefs where color communication is of vital *** addressed this knowledge gap by measuring flight initiation distance(the distance an individual moves away from an approaching threat)in dusky damselfish(Stegastes nigricans)in response to an approaching disc of 1 of 4 different color treatments:conspecific,blue,yellow,and *** the species confidence hypothesis explained variation in damselfish flight initiation distance,then we expected individuals to tolerate closer approaches when approached by a conspecific *** addition,we calculated the color difference between each stimulus and its corresponding back-ground as a potential alternative explanation for flight *** tolerated the closest approach from the conspecific color stimulus;there were no significant differences between other colors and there was no support for the alternative color difference *** with similar terrestrial studies,these results are relevant to ecotourists'choice of swimsuit and wetsuit colors because color choice may modify naturalantipredatorbehavior.

关键词： antipredator behavior flight initiation distance risk assessment species confidence hypothesis Stegastes nigricans

viral and nonviral nanocarriers for in vivo CRISPR-based gene editing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第10期17卷 8904-8925页

作者： Zhongyuan Guo Audrey t.Zhu Ronnie H.Fang Liangfang Zhang Aiiso Yufeng Li Family Department of Chemical and Nano Engineering University of California San DiegoLa JollaCA 92093USA Division of Host-Microbe Systems and therapeutics Department of PediatricsUniversity of California San DiegoLa JollaCA 92093USA

the continued development of clustered regularly interspaced short palindromic repeats(CRISPR)technology has the potential to greatly impact clinical medicine,particularly for disease diagnosis and *** high demand for the in vivo delivery of CRISPR-based therapies,significant challenges *** include rapid degradation by enzymes,inefficient disease site targeting,and the risk of undesired off-target *** platforms,with their tailorable properties,have been engineered to efficiently package CRISPR payloads in various formats,including as plasmid DNA,mRNA,and ribonucleoprotein complexes,for in vivo *** them,recombinant adeno-associated viruses,virus-like particles,and lipid nanoparticles have displayed exceptional *** review will discuss the development of these and other nanocarriers for in vivo CRISPR-based genome editing.

关键词： clustered regularly interspaced short palindromic repeats(CRISPR) in vivo gene editing nanocarriers recombinant adeno-associated viruses(rAAvs) virus-like particle(vLP) lipid nanoparticle(LNP)

Astrocytes dynamically regulate the blood-brain barrier in the healthy brain

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第4期19卷 709-710页

作者： AgnėPociūtė Augustas Pivoriūnas Alexei verkhratsky Department of Stem Cell Biology State Research Institute Centre for Innovative MedicineVilniusLithuania Faculty of Biology Medicine and HealthThe University of ManchesterManchesterUK Achucarro Centre for Neuroscience IKERBASQUEBasque Foundation for ScienceBilbaoSpain Department of Forensic Analytical toxicology School of Forensic MedicineChina Medical UniversityShenyangLiaoning ProvinceChina

the blood-brain barrier(BBB)(discovered and defined by Max Lewandowsky and Lina Stern,and not,as it is universally,and yet erroneously believed,by Paul Ehrlich(verkhratsky and Pivoriunas,2023))that separates the nervous system from the circulation is evolutionarily conserved from arthropods to *** primeval BBB of the invertebrates and some early vertebrates was made solely by glial cells and secured(in invertebrates)by septate junctions.

关键词： Ehrlich barrier blood