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Preface–Introduction to the Special Issue for Chinese-Russian Workshop on Biophotonics and Biomedical Optics

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 1-3页

作者： Tingting Yu Dan Zhu valery v.Tuchin Britton Chance Center for Biomedical Photonics-MoE Key Laboratory for Biomedical Photonics Advanced Biomedical Imaging FacilityWuhan National Laboratory for Optoelectronics–Advanced Biomedical Imaging FacilityHuazhong University of Science and TechnologyWuhan 430074China Department of Optics and Biophotonics Science Medical CenterSaratov State UniversitySaratov 410012Russia Laboratory of Laser Diagnostics of Technical and Living Systems Institute of Precision Mechanics and ControlFRC“Saratov Scientic Centre of the Russian Academy of Sciences”Saratov 410028Russia Laboratory of Laser Molecular Imaging and Machine Learning Tomsk State UniversityTomsk 634050Russia

The Chinese-Russian Workshop on Biophotonics and Biomedical Optics 2023 was held online twice on 18–21 September and 25–26 September *** bilateral workshop brought together both Russian and Chinese scientists,engineers,and clinical researchers from a variety of disciplines engaged in applying optical science,photonics,and imaging technologies to problems in biology and *** the workshops,two plenary lectures and twenty invited presentations were *** special issue selects some papers from both Russian and Chinese sides,consisting of one review and seven original research articles.

关键词： Russian photonics Biomedical

Spherically Symmetric Problem of General Relativity for a Fluid Sphere

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Journal of Modern Physics 2024年第4期15卷 401-415页

作者： valery v. vasiliev Leonid v. Fedorov Institute of Applied Mechanics of Russian Academy of Sciences Moscow Russia

The paper is devoted to a spherically symmetric problem of General Relativity (GR) for a fluid sphere. The problem is solved within the framework of a special geometry of the Riemannian space induced by gravitation. According to this geometry, the four-dimensional Riemannian space is assumed to be Euclidean with respect to the space coordinates and Riemannian with respect to the time coordinate. Such interpretation of the Riemannian space allows us to obtain complete set of GR equations for the external empty space and the internal spaces for incompressible and compressible perfect fluids. The obtained analytical solution for an incompressible fluid is compared with the Schwarzchild solution. For a sphere consisting of compressible fluid or gas, a numerical solution is presented and discussed.

关键词： General Relativity Spherically Symmetric Problem Fluid Sphere

Modern methods of underground hydromechanics with applications to reservoir engineering

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Journal of Hydrodynamics 2016年第6期28卷 937-946页

作者： Hua XIANG valery v.KADET Department of Petroleum and Underground Hydromechanics Gubkin Russian State University of Oil and Gas

In the report the basic principles of new approach to the study of transport processes in porous medium are represented. The ＂percolation＂ approach has arisen as an attempt to overcome the traditional phenomenological approach in the underground hydromechanics, based on the assumption of continuity of saturated porous media, which does not allow to explain and to model a number of effects arising from the fluids flow in porous media. The results obtained are very interesting not only from the scientific point of view but as the scientific basis for a number of enhanced oil recovery technologies.

关键词： fluid flow in porous media percolation theory relative phase permeability oil field development low salinity waterflooding

Anomalous Laterally Stressed Kinetically Trapped DNA Surface Conformations

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Nano-Micro Letters 2021年第8期13卷 263-280页

作者： valery v.Prokhorov Nikolay A.Barinov Kirill A.Prusakov Evgeniy v.Dubrovin Maxim D.Frank-Kamenetskii Dmitry v.Klinov Federal Research and Clinical Center of Physical-Chemical Medicine Malaya Pirogovskaya1aMoscow 119435Russian Federation A.N.Frumkin Institute of Physical Chemistry and Electrochemistry RASLeninsky prospect Moscow 199071 Russian Federation 3 Moscow Institute of Physics and TechnologyInstitutskiy per.9Dolgoprudny141700 MoscowRussian Federation Lomonosov Moscow State University Leninskie gory1-2Moscow 119991Russian Federation Department of Biomedical Engineering Boston University44 Cummington MallBoston MA02215USA

Up to now,the DNA molecule adsorbed on a surface was believed to always preserve its native *** belief implies a negligible contribution of lateral surface forces during and after DNA adsorption although their impact has never been ***-resolution atomic force microscopy was used to observe that stiff DNA molecules kinetically trapped on monomolecular films comprising one-dimensional periodically charged lamellar templates as a single layer or as a sublayer are oversaturated by sharp discontinuous kinks and can also be locally melted and *** argue that kink/anti-kink pairs are induced by an overcritical lateral bending stress(>30 pNnm)inevitable for the highly anisotropic 1D-1D electrostatic interaction of DNA and underlying rows of positive surface *** addition,the unexpected kink-inducing mechanical instability in the shape of the template-directed DNA confined between the positively charged lamellar sides is observed indicating the strong impact of *** previously reported anomalously low values of the persistence length of the surface-adsorbed DNA are explained by the impact of the surface-induced low-scale *** sites of the local melting and supercoiling are convincingly introduced as other lateral stress-induced structural DNA anomalies by establishing a link with DNA high-force *** results open up the study in the completely unexplored area of the principally anomalous kinetically trapped DNA surface conformations in which the DNA local mechanical response to the surface-induced spatially modulated lateral electrostatic stress is essentially *** underlying rich and complex in-plane nonlinear physics acts at the nanoscale beyond the scope of applicability of the worm-like chain approximation.

关键词： DNA surface conformations Kinetic trapping Lateral stress Periodically charged surface DNA kinks

Advances in small animal mesentery models for in vivo flow cytometry,dynamic microscopy,and drug screening

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World Journal of Gastroenterology 2007年第2期13卷 192-218页

作者： Ekaterina I Galanzha valery v Tuchin vladimir P Zharov Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Optics and Biomedical Physics Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Philips Classic Laser Laboratories University of Arkansas for Medical Sciences (UAMS) Little Rock AR United States

Using animal mesentery with intravital optical microscopy is a well-established experimental model for studying blood and lymph microcirculation in vivo. Recent advances in cell biology and optical techniques provide the basis for extending this model for new applications, which should generate significantly improved experimental data. This review summarizes the achievements in this specific area, including in vivo label-free blood and lymph photothermal flow cytometry, super-sensitive fluorescence image cytometry, light scattering and speckle flow cytometry, microvessel dynamic microscopy, infrared (IR) angiography, and high-speed imaging of individual cells in fast flow. The capabilities of these techniques, using the rat mesentery model, were demonstrated in various studies; e.g., real-time quantitative detection of circulating and migrating individual blood and cancer cells, studies on vascular dynamics with a focus on lymphatics under normal conditions and under different interventions (e.g. lasers, drugs, nicotine), assessment of lymphatic disturbances from experimental lymphedema, monitoring cell traffic between blood and lymph systems, and high-speed imaging of cell transient deformability in flow. In particular, the obtained results demonstrated that individual cell transportation in living organisms depends on cell type (e.g., normal blood or leukemic cells), the cell’s functional state (e.g., live, apoptotic, or necrotic), and the functional status of the organism. Possible future applications, including in vivo early diagnosis and prevention of disease, monitoring immune response and apoptosis, chemo- and radio-sensitivity tests, and drug screening, are also discussed.

关键词： Lymph microcirculation Transmission digital microscopy Rat mesentery Flow cytometry Photothermal technique

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FOREWORD

Journal of Innovative Optical Health Sciences 2009年第1期2卷 I0001-I0002页

作者： Elina A.Genina Kirill v.Larin valery v.Tuchin Research-Educational Institute of Optics and Biophotonics Saratov State University Saratov Russia Department of Biomedical Engineering University of Houston Houston USA Research-Educational Institute of Optics and Biophotonics Saratov State University Institute of Precise Mechanics and Control RAS Saratov Russia

Special Issue Optical Technologies in the Study of Tissues and Biological Fluids We are pleased to present this special issue of JIOHS,which focuses on optical technologies in the study of tissues and biological *** selected papers were presented during Saratov Fall Meeting—XII International School for Junior Scientists and Students on Optics,Laser Physics and Biophotonics(September 23–26,2008,Saratov,Russia)in the framework of the following workshops:“Optical Technologies in Biophysics and Medicine,”“Nanostructures and Nanoparticles,”“Microscopic and Low-Coherence Methods in Biomedical Applications,”and“Internet Biophotonics.”All eight papers in this special issue are research papers.

关键词： Junior photonics Russia

ASSESSMENT OF TISSUE OPTICAL CLEARING AS A FUNCTION OF GLUCOSE CONCENTRATION USING OPTICAL COHERENCE TOMOGRAPHY

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Journal of Innovative Optical Health Sciences 2010年第3期3卷 169-176页

作者： NARENDRAN SUDHEENDRAN MOHAMED MOHAMED MOHAMAD G.GHOSN valery v.TUCHIN KIRILL v.LARIN Department of Electrical and Computer Engineering University of Houston N308 Engineering Building 1 HoustonTX 77204USA Department of Biomedical Engineering University of Houston 2028 SERC Building HoustonTX 77204USA Department of Medicine Baylor College of Medicine HoustonTX 77030USA Institute of Optics and Biophotonics Saratov State University Saratov 410012Russia Institute of Precise Mechanics and Control of RAS Saratov 410056 Russia

One of the major challenges in imaging biological tissues using optical techniques,such as optical coherence tomography(OCT),is the lack of light penetration due to highly turbid structures within the *** clearing techniques enable the biological samples to be more optically homogeneous,allowing for deeper penetration of light into the *** study investigates the effect of optical clearing utilizing various concentrations of glucose solution(10%,30%,and 50%)on porcine skin.A gold-plated mirror was imaged beneath the tissue and percentage clearing was determined by monitoring the change in reflected light intensity from the mirror over *** ratio of percentage clearing per tissue thickness for 10%,30% and 50% glucose was determined to be 4.7±1.6%mm^(−1)(n=6),10.6±2.0%mm^(−1)(n=7)and 21.8±2.2%mm^(−1)(n=5),*** was concluded that while higher glucose concentration has the highest optical clearing effect,a suitable concentration should be chosen for the purpose of clearing,considering the osmotic stress on the tissue sample.

关键词： Glucose porcine skin percent clearing scattering coefficient optical coherence tomography

Shedding light on biology and healthcare--preface to the special issue on Biomedical Optics

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Light(Science & Applications) 2022年第7期11卷 1315-1317页

作者： Peng Xi Xunbin Wei Junle Qu valery v.Tuchin Department of Biomedical Engineering College of Future TechnologyPeking University100871BeijingChina Department of Biomedical Engineering Peking University100081BeijingChina Center for Biomedical Optics and Photonics(CBOP)&College of Physics and Optoelectronic Engineering Key Laboratory of Optoelectronic Devices and Systems of Guangdong Province and Ministry of EducationShenzhen University518060ShenzhenChina Saratov State University 83 Astrakhanskaya str.Saratov410012Russia

During the past decade,there has been an explosion in the development of novel optical techniques in biomedical research and clinical *** progress has been made in optical imaging and detection to provide necessary biological information for disease diagnosis and in-depth understanding of biological ***,recent advances integrating laser technology with biomarkers have enabled novel diagnostic and treatment approaches for different types of diseases.

关键词： optical integrating diagnosis

INTRODUCTION:SPECIAL ISSUE ON ADvANCES IN BIOPHOTONICS AND BIOMEDICAL OPTICS-PART I

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Journal of Innovative Optical Health Sciences 2013年第2期6卷 16-17页

作者： Dan Zhu valery v.Tuchin Qingming Luo Huazhong University of Science and Technology WuhanP.R.China Saratov State University SaratovRussia

The 5th Russian-Chinese Workshop on Biophotonics and Biomedical Optics was hosted in Saratov,Russia on 26-28,September,*** bilateral Workshop brought together both Russian and Chinese scientists,engineers and clinical researchers from a variety of disciplines engaged in applying optical science,photonics and imaging technologies to problems in biology and *** the W orkshop,2 plenary lectures,11 invited presentations,4 oral presentations and 13 poster reports were presented.A special Internet session with 5 presentations-1 plenary,2 invited,and 2 posters was also *** special issue selects some papers from the attendees,and is made up of 12 original research articles and one *** articles will be presented in vol.6 No.1 of JIOHS,while the remaining five articles will be presented in vol.6 No.2.

关键词： Russian photonics engineer