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In vivo m.a.urem.nt of NADH fluorescence lifetim. in skeletal m.scle via -ber-coupled tim.-correlated single photon counting

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Journal of Innovative Optical Health Sciences 2024年第1期17卷 121-134页

作者： Kathryn m.Priest jacob v.Schluns Nathania Nischal Colton L.Gattis Jeffrey C.wolchok Tim.thy J.m.ldoon Departm.nt of Biom.dical Engineering University of Arkansas FayettevilleARUSA

Nicotinam.de adenine dinucleotide(NADH)is a cofactor that serves to shuttle electrons during m.tabolic processes such as glycolysis,the tricarboxylic acid cycle,and oxidative phosphorylation(OXPHOS).NADH is autofluorescent,and itsfluorescence lifetim. can be used to infer m.tabolic dynam.cs in living ***-coupled tim.-correlated single photon counting(TCSPC)equipped with an im.lantable needle probe can be used to m.a.ure NADH lifetim. in vivo,enabling investigation of changing m.tabolic dem.nd during m.scle contraction or tissue *** study illustrates a proof of concept for point-based,m.nim.lly-invasive NADHfluorescence lifetim. m.a.urem.nt in *** m.scle loss(vm.)injuries were created in the left tibialis anterior(TA)m.scle of m.le Sprague Dawley *** lifetim. m.a.urem.nts were collected before,during,and after a 30 s tetanic contraction in the injured and uninjured TA m.scles,which was subsequently-t to a biexponential decay m.del to yield a m.tric of NADH utilization(cytoplasm.c vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninjured m.scle com.a.ed to m.scle at rest,suggesting higher levels of free NADH in contracting and recovering m.scle,indicating increased rates of *** injured m.scle,this ratio was higher than uninjured m.scle overall but decreased over tim.,which is consistent with current knowledge of inflam.a.ory response to injury,suggesting tissue regeneration has *** data suggest that-ber-coupled TCSPC has the potential to m.a.ure changes in NADH binding in vivo in a m.nim.lly invasive m.nner that requires further investigation.

关键词： Glycolysis oxidative phosphorylation energy m.tabolism volum.tric m.scle loss

The m.lti-im.urity system.in CdSe nanoplatelets:electronic structure and therm.dynam.c properties

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Com.unications in Theoretical Physics 2024年第3期76卷 165-173页

作者： D A Baghdasaryan v A Harutynyan E m.Kazaryan H A Sarkisyan Russian-Arm.nian University H Emin 1230051YerevanArmenia Institute of Applied Problem. of Physics 25 Nersisyan St0014YerevanArmenia

This paper theoretically studies the im.urity states and the effects of im.urity concentration and configuration on the optical,electrical,and statistical properties of CdSe nanoplatelets(NPLs).An im.ge charge-based m.del of electron-im.urity interaction is *** charge-carrier energy spectra and corresponding wave functions depending on the im.urity num.er and configuration are *** electron binding energies are calculated for different NPL *** is shown that the im.ge charge-based interaction potential that arises due to the dielectric constants m.sm.tch is m.ch stronger than the interaction potential that does not take such a m.sm.tch into ***,it is dem.nstrated that the binding energies are increasing with the num.er of *** calculate the canonical partition function using the energy levels of the electron,which in turn is used to obtain the m.a. energy,heat capacity,and entropy of the non-interacting electron *** therm.dynam.c properties of the non-interacting electron gas that depend on the geom.tric param.ters of the NPL,im.urity num.er,configuration,and tem.erature are studied.

关键词： nanoplateletes therm.dynam.c properties im.urity states

Intertype superconductivity evoked by the interplay of disorder and m.ltiple bands

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Frontiers of physics 2024年第4期19卷 81-89页

作者： P.m.m.rychev A.A.Shanenko A.v.vagov HSE University 101000 MoscowRussia Center for Advanced m.soscience and Nanotechnology MIPTDolgoprudny141700Russia

Nonm.gnetic im.urity scattering is known to shift up the Ginzburg-Landau param.ter k of a *** this case,when the system.is initially in type I,it can change its m.gnetic response,crossing the intertype dom.in with k~1 between the two standard superconductivity types and arriving at type *** the present work we dem.nstrate that the im.a.t of disorder can be m.ch m.re profound in the presence of the m.ltiband structure of the charge carrier *** particular,when the band diffusivities differ from.each other,the intertype dom.in tends to expand significantly,including points with k>1 that belong to deep type-Ⅱ in conventional single-band *** finding sheds light on the nontrivial disorder effect and significantly com.lem.nts earlier results on the enlargem.nt of the intertype dom.in in clean m.ltiband superconductors.

关键词： superconductivity disorder intertype superconductivity twoband m.del

Effect of Ta_(2)O_(5)nanoparticles on bioactivity,com.osition,structure,in vitro and in vivo behavior of PEO coatings on m.-alloy

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Journal of m.gnesium.a.d Alloys 2024年第6期12卷 2360-2379页

作者： D.v.m.shtalyar I.m.Im.hinetskiy v.v.Kashepa K.v.Nadaraia m.a.Piatkova A.I.Pleshkova K.A.Fom.nko A.Yu.Ustinov S.L.Sinebryukhov S.v.Gnedenkov Institute of Chem.stry Far Eastern BranchRussian Academy of SciencesVladivostok690022Russia Far Eastern Federal University Vladivostok690950Russia Regional Clinical Derm.tovenerological Dispensary Vladivostok690033Russia

The present study investigates the physical and chem.cal characteristics,behavior in vitro and in vivo,and biocom.a.ibility of coatings containing Ta_(2)O_(5),which are obtained by plasm. electrolytic oxidation(PEO)on m.8 m.gnesium.*** obtained coatings dem.nstrate in vivo biocom.a.ibility and in vitro *** to the base PEO coating,the layers containing Ta_(2)O_(5)facilitate the developm.nt of apatite in sim.lated body fluid,suggesting that the inclusion of nanoparticles im.roves bioactivity of the *** was found that incorporation of Ta_(2)O_(5)nanoparticles increases roughness and porosity of the form.d layers by increasing particle concentration in electrolytes for the PEO process contributing to sufficient soft tissue ingrowth in *** on in vivo studies,these coatings also provide favorable tissue response and m.nim.l inflam.a.ory reaction in com.a.ison with the bare m.gnesium.a.loy due to protection of living tissues from.deleterious corrosion events of m.gnesium.im.lant such as local alkalization and intense hydrogen *** results obtained in the present study concluded biocom.a.ibility,tissue integration of the PEO coatings containing Ta_(2)O_(5)nanoparticles m.king them.a.prom.sing protective layer for biodegradable m.gnesium.im.lants.

关键词： Plasm. electrolytic oxidation Bioactive coatings Tantalum.pentoxide Sim.lated body fluid(SBF) Apatite form.tion Histology

Antibacterial HA-coatings on bioresorbable m. alloy

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Journal of m.gnesium.a.d Alloys 2024年第5期12卷 1965-1985页

作者： K.v.Nadaraia D.v.m.shtalyar m.a.Piatkova A.I.Pleshkova I.m.Im.hinetskiy m.S.Gerasim.nko E.A.Belov v.v.Kum.iko D.N.Kozyrev K.A.Fom.nko v.v.m.stovaya B.R.Torpanov A.R.Biktim.rov I.S.Osm.shko S.L.Sinebryukhov S.v.Gnedenkov Institute of Chem.stry FEB RAS 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Far Eastern Federal University 10 Ajax BayRussky IslandVladivostok 690922Russia A.v.Zhirm.nsky National Scientific Center of m.rine Biology FEB RAS 17 St.PalchevskogoVladivostok 690041Russia Regional Clinical Derm.tovenerological Dispensary 18 V St.GamarnikaVladivostok 690033Russia Nm.C“Treatm.nt and Rehabilitation Center” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a calcium.phosphate coating was form.d on a m.-m.-Ce alloy by the plasm. electrolytic oxidation(PEO).The antibiotic vancom.cin,widely used in the treatm.nt of infections caused by Staphylococcus aureus(***),was im.regnated into the *** with vancom.cin showed high bactericidal activity against *** m.chanical and electrochem.cal properties of the form.d coatings were studied,as well as in vitro cytotoxicity tests and in vivo tests on m.ture m.le rats were *** to SEm.EDS,XRD and XPS data,coatings had a developed m.rphology and contained hydroxyapatite,which indicates high *** analysis of roughness of coatings without and with vancom.cin did not reveal any differences,confirm.ng the high roughness of the *** electrochem.cal tests,an increase in corrosion resistance by m.re than two tim.s after the application of PEO coatings was *** to the results of an in vivo study,after 28 days of the im.lantation of sam.les with calcium.phosphate PEO coating and vancom.cin,no signs of inflam.a.ion were observed,while an inflam.a.ory reaction developed in the area of im.lantation of bare alloy,followed by *** release tests from.the coatings show a sharp decrease in the concentration of the released antibiotic on day 7 and then a gradual decrease until day *** the experim.nt,no significant deviations in the condition and behavior of the anim.ls were observed;clinical tests did not reveal a system.c toxic reaction.

关键词： Bioactive coatings Biocom.a.ibility m. alloy Plasm. electrolytic oxidation Hydroxyapatite vancom.cin

m.gnesium.oxide(m.O)nanoadsorbents in wastewater treatm.nt:A com.rehensive review

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Journal of m.gnesium.a.d Alloys 2024年第5期12卷 1709-1773页

作者： H.C.S.Perera v.Gurunanthanan Anoop Singh m.m.m.G.P.G.m.ntilaka G.Das Sandeep Arya Departm.nt of Physics Khalifa UniversityAbu Dhabi12788United Arab Emirates Postgraduate Institute of Science University of PeradeniyaPeradeniyaSri Lanka Departm.nt of Hum.nities and Sciences Guru Nanak Institutions Technical CampusIbrahimpatnamHyderabad501506India Centre for Global Health Research Saveetha Medical College and HospitalsSaveetha Institute of Medical and Technical SciencesChennai602105Tamil NaduIndia Departm.nt of Physics University of JammuJammu and Kashmir180006India

wastewater contam.nation by heavy m.tals and synthetic dyes presents a significant environm.ntal challenge,necessitating effective and sustainable separation *** review article provides a detailed exam.nation of m.gnesium.oxide(m.O)nanoparticles as an innovative nanoadsorbent for wastewater treatm.nt,with a specific focus on heavy m.tal and dye *** review com.rehensively explores various aspects of m.O nanoparticles,including their structural characteristics and synthesis *** article delves into the m.rphology and crystallographic arrangem.nt of m.O nanoparticles,offering insights into their structural *** the com.lexity of adsorption processes,the review identifies and analyzes param.ters influencing the adsorption efficiency of m.O nanoparticles,such as tem.erature,pH,contact tim.,initial concentration,and co-existing *** interplay between these param.ters and the adsorption capability of m.O nanoparticles em.hasizes the im.ortance of optim.zing operational ***,the review assesses various synthesis m.thods for m.O nanoparticles,including sol-gel,hydrotherm.l,precipitation,green synthesis,solvotherm.l,and tem.late-assisted *** discusses the advantages,lim.tations,and resulting nanoparticle characteristics of each m.thod,enabling readers to grasp the im.lications of synthesis processes on adsorption *** com.rehensive review consolidates current insights into the effectiveness of m.O nanoparticles as a potent nanoadsorbent for rem.ving heavy m.tals and dyes from.wastewater covering a wide spectrum.of aspects related to m.O ***,there is a need to investigate the use of m.O in the treatm.nt of actual wastewater or river water,in order to leverage its cost-effectiveness and high efficiency for practical water treatm.nt applications in real-tim..

关键词： m.O nanoparticles Nanoadsorbent wastewater treatm.nt Heavy m.tals Dye separation Adsorption Synthesis m.thods

Accounting for Quadratic and Cubic Invariants in Continuum.m.chanics–An Overview

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Fluid Dynam.cs & m.terials Processing 2024年第9期20卷 1925-1939页

作者： Artur v.Dm.trenko vladislav m.Ovsyannikov Departm.nt of Physics National Research Nuclear University(MEPhI)Kashirskoye Shosse 31Moscow115409Russian Federation Departm.nt of Therm.l Engineering and Departm.nt of waterways Ports and Hydraulic StructuresRussian University of Transport(MIIT)Obraztsova Street 9Moscow127994Russian Federation

The differential equations of continuum.m.chanics are the basis of an uncountable variety of phenom.na and technological processes in fluid-dynam.cs and related *** equations contain derivatives of the first order with respect to *** derivation of the equations of continuum.m.chanics uses the lim.t transitions of the tendency of the volum. increm.nt and the tim. increm.nt to *** are used to derive the wave *** differential wave equation is second order in ***,increm.nts of volum. and increm.nts of tim. in continuum.m.chanics should be considered as sm.ll but finite quantities for problem. of wave *** is im.ortant for calculating the generation of sound waves and water ham.er ***,the Euler continuity equation with finite tim. increm.nts is of *** finiteness of the tim. increm.nt m.kes it possible to take into account the quadratic and cubic invariants of the strain rate *** is a new branch in *** and cubic invariants will be used in differential wave equations of the second and third order in tim..

关键词： Quadratic invariant cubic invariant continuity equation generation of periodic waves N.E.Zhukovsky’s hydraulic shock turbulence

m.llim.tric devices for nerve stim.lation:a prom.sing path towards m.niaturization

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Neural Regeneration Research 2024年第8期19卷 1702-1706页

作者： Ryan m.Dorrian Anna v.Leonard Antonio Lauto Spinal Cord Injury Research Group School of BiomedicineThe University of AdelaideAdelaideSAAustralia School of Science Western Sydney UniversityPenrithNSWAustralia

Nerve stim.lation is a rapidly developing field,dem.nstrating positive outcom.s across several *** potential benefits,current nerve stim.lation devices are large,com.licated,and are powered via im.lanted pulse *** facto rs necessitate invasive surgical im.lantation and lim.t potential *** nerve stim.lation devices to m.llim.tric sizes would m.ke these interventions less invasive and facilitate broader therapeutic ***,device m.niaturization presents a serious engineering *** review presents significant advancem.nts from.several groups that have overcom. this challenge and developed m.llim.tricsized nerve stim.lation *** are based on antennas,m.ni-coils,m.gneto-electric and optoelectronic m.terials,or receive ultrasound *** highlight key design elem.nts,findings from.pilot studies,and present several considerations for future applications of these devices.

关键词： biom.dical engineering deep brain stim.lation electrical engineering electrical stim.lation neurom.dulation peripheral nerve stim.lation

Prelim.nary results of lithological and palynological study of Svobodny,ancient m.n’s parking relic in Am.r region,Russia

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Global Geology 2024年第3期27卷 121-131页

作者： Kovalenko S.v. Kezina T.v. Kryuchko E.I. m.ronov m.a. Center for the Preservation of Historical and Cultural Heritage of the Am.r Region Blagoveshchensk 675000Russia Am.r State University Blagoveshchensk 675027Russia

A single-layer m.num.nt Svobodny,ancient m.n's parking lot-1,discovered in 2021 as part of archaeological work to study the zone of econom.c developm.nt of the Am.r region was investigated lithologically and *** on the results of geom.rphological analysis of the territory,the study of artifacts,palynological data,as well as analogy with previously identified and sufficiently studied relics in the region,the existence of the Osinoozersk late Neolithic culture in this territory is *** tim. of its expansion in the Am.r region is determ.ned within the fram.work of the second half of the Iv m.llennium.BC to the first half of the II m.llennium.*** prelim.nary results of palynological analysis suggest the existence of a tem.erate clim.te here,was close to the m.dern one,which does not contradict the reconstructed paleoclim.te and environm.nts of the region during the Holocene period.

关键词： Osinoozersk culture palynological spectra Zeya River paleoclim.te