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Design of a robust PID-PSS for an uncertain power system with simplified stability conditions

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Protection and Control of Modern Power Systems 2020年第1期5卷 222-237页

作者： vijaya Lakshmi A.S.v Ramalinga Raju Manyala siva kumar Mangipudi Department of EEE G.V.P College of Engineering for WomenVisakhapatnamIndia Department of EEE JNTU KakinadaKakinadaIndia Department of EEE Gudlavalleru Engineering CollegeGudlavalleruAndhra PradeshIndia

In a deregulated power system uncertainty exists and lack of sufficient damping can lead to Low FrequencyOscillations (LFO). The problem can be addressed using robust Power System Stabilizers (PSS). In this paper, anoptimal procedure to design a robust PID-PSS using interval arithmetic for the Single Machine Infinite Bus (SMIB)power system is proposed. The interval modelling captures the wide variations of operating conditions in boundsof system coefficients. In the proposed design procedure, simple and new closed loop stability conditions for anSMIB interval system are developed and are used to design an optimum PID-PSS for improving the performance ofan SMIB system. The optimum PID-PSS is attained by tuning the parameters using the FMINCON tool provided inMATLAB. The robustness of the proposed PID-PSS design is validated and compared to other notable methods inthe literature when the system is subjected to different uncertainties. The simulation results and performance errorvalues show the effectiveness of the proposed robust PID-PSS controller.

关键词： Low frequency oscillations Uncertainty Power system stabilizer Robust controller Interval systems

Peroxisome proliferator-activated receptor agonists:A new hope towards the management of alcoholic liver disease

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World Journal of Gastroenterology 2024年第35期30卷 3965-3971页

作者： siva Sundara kumar Durairajan Abhay kumar Singh Ashok Iyaswamy Department of Microbiology School of Life SciencesCentral University of Tamil NaduTiruvarur 610005India School of Biomedical Sciences Li Ka Shing Faculty of MedicineUniversity of Hong KongHong Kong 999077China School of Chinese Medicine Hong Kong Baptist UniversityHong Kong 999077China Department of Biochemistry Karpagam Academy of Higher EducationCoimbatore 641021India

In this editorial,we examine a paper by Koizumi et al,on the role of peroxisome proliferator-activated receptor(PPAR)agonists in alcoholic liver disease(ALD).The study determined whether elafibranor protected the intestinal barrier and reduced liver fibrosis in a mouse model of *** study also underlines the role of PPARs in intestinal barrier function and lipid homeostasis,which are both affected by *** therapies are necessary for ALD because it is a critical health issue that affects people *** editorial analyzes the possibility of PPAR agonists as treatments for *** key factors of inflammation and metabolism,PPARs offer multiple methods for managing the complex etiology of *** assess the abilities of PPARα,PPARγ,and PPARβ/δagonists to prevent steatosis,inflammation,and fibrosis due to liver *** research carried out in preclinical and clinical settings has shown that PPAR agonists can reduce the severity of liver *** editorial discusses the data analyzed and the obstacles,advantages,and mechanisms of action of PPAR agonists for *** research is needed to understand the efficacy,safety,and mechanisms of PPAR agonists for treating ALD.

关键词： Alcoholic liver disease Peroxisome proliferator-activated receptors Peroxisome proliferator-activated receptors agonists Liver fibrosis Inflammation Metabolic regulation Hepatoprotection

volumetric, Ultrasonic and Transport Properties of Binary Liquid Mixtures Containing Dimethyl Formamide at 303.15 K

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Chinese Journal of Chemistry 2007年第1期25卷 32-43页

作者： SYAMALA, vardhana RAJA SEKHAR, Damaramadugu siva kumar, Kasibhatta vENKATESWARLU, Ponneri Thermochemical Laboratories Department of Chemistry Sri Venkateswara University Tirupati 517 502 India Department of Chemistry SVArts College Tirupati 517 502 India

Excess volumes （v^E）, ultrasonic velocities （u）, isentropic compressibility （△Ks） and viscosities （η） for the binary mixtures of dimethyl formamide （DMF） with 1,2-dichlorobenzene, 1,3-dichlorobenzene, 1,2,4-trichlorobenzene, o-chlorotoluene, m-chlorotoluene, p-chlorotoluene, o-nitrotoluene and m-nitrotoluene at 303.15 K were studied. Excess volume data exhibit an inversion in sign for the mixtures of dimethyl formamide with 1,2- and 1,3-dichlorobenzenes and the property is completely positive over the entire composition range for the mixtures of dimethyl formamide with 1,2,4-trichlorobenzene, o-nitrotoluene and m-nitrotoluene. On the other hand, the quantity is negative for the mixtures of dimethyl formamide with chlorotoluenes. Isentropic compressibility （Ks） has been computed for the same systems from precise sound velocity and density data. Further, deviation of isentropic com- pressibility （△Ks） from ideal behavior was also calculated. AKs values are negative over the entire volume fraction range in all the binary mixtures. The experimental sound velocity data were analysed in terms of Free Length Theory （FLT） and Collision Factor Theory （CFT）. The viscosity data were analysed on the basis of corresponding state approach. The measured data were discussed on the basis of intermolecular interactions between unlike molecules.

关键词： excess volume, dimethyl formamide, interferometer, sound velocity, viscosity molecular interaction

Elucidating the role of gut microbiota dysbiosis in hyperuricemia and gout:Insights and therapeutic strategies

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World Journal of Gastroenterology 2024年第40期30卷 4404-4410页

作者： Abhay kumar Singh siva Sundara kumar Durairajan Ashok Iyaswamy Leonard L Williams Department of Microbiology School of Life SciencesCentral University of Tamil NaduTiruvarurTN 610005India School of Biomedical Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong 999077China School of Chinese Medicine Hong Kong Baptist UniversityHong Kong 999077China Department of Biochemistry Karpagam Academy of Higher EducationCoimbatore 641021India Center for Excellence in Post-Harvest Technologies North Carolina Agricultural and Technical State UniversityGreensboroNC 27411United States

Hyperuricemia(HUA)is a condition associated with a high concentration of uric acid(UA)in the bloodstream and can cause gout and chronic kidney *** gut microbiota of patients with gout and HUA is significantly altered compared to that of healthy *** article focused on the complex interconnection between alterations in the gut microbiota and the development of this *** studies have suggested that changes in the composition,diversity,and activity of microbes play a key role in establishing and progressing HUA and gout ***,we discussed how the gut microbiota contributes to HUA through purine metabolism,UA excretion,and intestinal inflammatory *** examined specific changes in the composition of the gut microbiota associated with gout and HUA,highlighting key bacterial taxa and the metabolic pathways ***,we discussed the effect of conventional gout treatments on the gut microbiota composition,along with emerging therapeutic approaches that target the gut microbiome,such as the use of probiotics and *** also provided insights into a study regarding the gut microbiota as a possible novel therapeutic intervention for gout treatment and dysbiosis-related diagnosis.

关键词： Gut microbiota Dysbiosis Gout Hyperuricemia Inflammation Intestinal barrier Probiotics Prebiotics Fecal microbiota transplantation

Structure, photocatalytic and antibacterial activity study of Meso porous Ni and S co-doped TiO2 nano material under visible light irradiation

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Chinese Journal of Chemical Engineering 2019年第7期27卷 1630-1641页

作者： K.v.Divya Lakshmi T.siva Rao J.Swathi Padmaja I.Manga Raju M.Ravi kumar Department of Inorganic and Analytical Chemistry Andhra University

Undoped and Ni–S co-doped mesoporous TiO2 nano materials were synthesized by using sol–gel *** characteristic features of as prepared catalyst samples were investigated using various advanced spectroscopic and analytical *** characterization results of the samples revealed that all the samples exhibited anatase phase(XRD),decreasing band gap(2.68 ev)(Uv–vis-DRS),small particle size(9.2 nm)(TEM),high surface area(142.156 m^2·g^-1)(BET),particles with spherical shape and smooth morphology(SEM);there is a frequency shift observed for co-doped sample(FT-IR)and the elemental composition electronic states and position of the doped elements(Ni and S)in the TiO2 lattice analyzed by XPS and *** results supported the photocatalytic degradation of Bismarck Brown Red(BBR)achieved with in 110 min and also exhibited the antibacterial activity on Staphylococcus aureus(MTCC-3160),Pseudomonas fluorescence(MTCC-1688)under visible light irradiation.

关键词： Sol–gel Ni–S co-doped TiO2 Photocatalysis under visible light Degradation of Bismarck Brown Red Antibacterial activity

Mechanical properties of Ni_(0.83)Co_(0.15)Cu_(0.02)Fe_(1.9)O_(4-δ)+PbZr_(0.52)Ti_(0.48)O_(3)particulate composites by composite oscillator technique and the correlation with the results of magnetoelectric properties

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Journal of Advanced Ceramics 2012年第4期1卷 317-326页

作者： M.venkata RAMANA M.Penchal REDDY N.Ramamanohar REDDY B.S.MURTY K.v.siva kumar Shenhua SONG Shenzhen Key Laboratory of Advanced Materials Department of Materials Science and EngineeringShenzhen Graduate SchoolHarbin Institute of TechnologyShenzhen 518055China Department of Physics Changwon National UniversityChangwonRepublic of Korea Ceramic Composite Materials Laboratory Department of PhysicsSri Krishnadevaraya UniversityAnantapur 515003India Nanotechnology Laboratory Department of Metallurgical and Materials EngineeringIndian Institute of TechnologyChennai 600036India

The xNi_(0.83)Co_(0.15)Cu_(0.02)Fe_(1.9)O_(4-δ)+PbZr_(0.52)Ti_(0.48)O_(3)(PZT)particulate magneto ferroelectric composites with x=0,0.1,0.2,0.3,0.4,0.5 and 0.6 mole fraction were prepared by conventional ceramic double sintering *** presence of two phases(perovskite structure of ferroelectric phase and spinal structure of ferromagnetic phase)was confirmed by X-ray *** magnetoelectric(ME)property of the particulate composites was determined at room temperature as a function of intensity of magnetic *** temperature variation of the longitudinal modulus(L)and the internal friction(Q−1)of these particulate composites at 104.3 kHz was studied in the wide temperature range 30-420℃.The temperature variation of the longitudinal modulus in each composition of these particulate composites showed two abrupt *** minimum coincided with the ferroelectric-paraelectric Curie transition temperature(θE)and the other with the ferromagnetic-paramagnetic Curie transition temperature(θM).The internal friction measurement also showed two sharp peaks in each composition corresponding to those temperatures where the minima were noticed in the temperature variation of the longitudinal modulus behaviour.

关键词： X-ray diffraction magnetoelectric effect piezoelectric coefficient internal friction Curie transition temperature

Role of Candida species in pathogenesis, immune regulation, and prognostic tools for managing ulcerative colitis and Crohn's disease

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World Journal of Gastroenterology 2024年第48期30卷 5212-5220页

作者： Supriti Patnaik siva Sundara kumar Durairajan Abhay kumar Singh Senthilkumar Krishnamoorthi Ashok Iyaswamy Shiva Prasad Mandavi Rajesh Jeewon Leonard L Williams Molecular Mycology and Neurodegenerative Disease Research Laboratory Department of MicrobiologyCentral University of Tamil NaduThiruvarur 610005India School of Biomedical Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongPokfulamHong Kong SARChina Mr.&Mrs Ko Chi-Ming Centre for Parkinson’s Disease Research School of Chinese MedicineHong Kong Baptist UniversityHong Kong SARChina Department of Biochemistry Karpagam Academy of Higher EducationCoimbatore 641021India Department of Chemistry Central University of Tamil NaduTiruvarur 610005India Department of Health Sciences Faculty of Medicine and Health SciencesUniversity of MauritiusReduit 80837Mauritius Department of Zoology College of ScienceKing Saud UniversityRiyadh 11451Saudi Arabia Center for Excellence in Post Harvest Technologies North Carolina Agricultural and Technical State UniversityThe North Carolina Research CampusKannapolisNC 28081United States

The gut microbiome plays a key role in the pathogenesis and disease activity of inflammatory bowel disease(IBD).While research has focused on the bacterial microbiome,recent studies have shifted towards host genetics and host-fungal *** mycobiota is a vital component of the gastrointestinal microbial community and plays a significant role in immune *** fungi,Candida species,particularly Candida albicans(***),have been extensively studied due to their dual role as gut commensals and invasive *** findings indicate that various strains of *** exhibit consid-erable differences in virulence factors,impacting IBD's *** fungal dysbiosis and antifungal mucosal immunity may be associated to IBD,especially Crohn's disease(CD).This article discusses intestinal fungal dysbiosis and antifungal immunity in healthy individuals and CD *** discusses factors influencing the mycobiome's role in IBD pathogenesis and highlights significant contributions from the scientific community aimed at enhancing understanding of the mycobiome and encouraging further research and targeted intervention studies on specific fungal *** article also provided insights into a recent study by Wu et al in the World Journal of Gastroenterology regarding the role of the gut microbiota in the pathogenesis of CD.

关键词： Inflammatory bowel disease Ulcerative colitis Crohn's disease Gut mycobiome dysbiosis Candida species Immune regulation Gut inflammation Fecal mycobiota transplantation

SYNTHESIS OF LEAD FREE SODIUM BISMUTH TITANATE(NBT)CERAMIC BY CONvENTIONAL AND MICROWAvE SINTERING METHODS

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Journal of Advanced Dielectrics 2011年第1期1卷 71-77页

作者： M.vENKATA RAMANA S.ROOPAS KIRAN N.RAMAMANOHAR REDDY K.v.siva kumar v.R.K.MURTHY B.S.MURTY Ceramic Composite Materials Laboratory Department of Physics Sri Krishnadevaraya UniversityAnantapur 515003India Microwave Laboratory Department of Physics Indian Institute of Technology Chennai 600036India Nanotechnology Laboratory Department of Metallurgical and Materials Engineering Indian Institute of Technology Chennai 600036 India

Dielectric studies were carried out on a lead free Sodium Bismuth Titanate,NBT,(Na_(0.5)Bi_(0.5)TiO_(3))*** material was synthesized by conventional ceramic method(CS)and microwave sintering(MS).The presence of single phase has been confirmed by X-ray diffraction and scanning electron microscopy of NBT *** later technique(MS)resulted in material with high density,dielectric properties and improved *** transition temperature was observed slightly higher for microwave sintered(MS)*** modulus measurements are very sensitive property to identify the phase transitions in *** modulus(L)measurements were also employed on these samples in the frequency 136 kHz and can be studied in the wide temperature range 30℃to 400℃.The elastic behavior(L)showed a break at two temperatures(~200℃and 350℃)in both the conventional and microwave sintered *** NBT ceramics,permittivity anomalies are connected to modulus *** results are correlated with the dielectric *** behavior explained in the light of structural phase transitions in the ferroelectric ceramics.

关键词： Microwave sintering NBT X-ray diffractometer scanning electron microscopy dielectric properties longitudinal modulus

Animal models for SARS-Cov-2 and SARS-Cov-1 pathogenesis,transmission and therapeutic evaluation

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World Journal of virology 2022年第1期11卷 40-56页

作者： Udhaya Bharathy Saravanan Mayurikaa Namachivayam Rajesh Jeewon Jian-Dong Huang siva Sundara kumar Durairajan Department of Microbiology School of Life SciencesCentral University of Tamil NaduTiruvarur 610005India Department of Health Sciences Faculty of Medicine and Health SciencesUniversity of MauritiusReduit 80837Mauritius CAS Key Laboratory of Quantitative Engineering Biology Shenzhen Institute of Synthetic BiologyShenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhen 518055Guangdong ProvinceChina

There is a critical need to develop animal models to alleviate vaccine and drug development difficulties against zoonotic viral *** coronavirus family,which includes severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2,crossed the species barrier and infected humans,causing a global outbreak in the 21st *** humans do not have pre-existing immunity against these viral infections and with ethics governing clinical trials,animal models are therefore being used in clinical studies to facilitate drug discovery and testing efficacy of *** ideal animal models should reflect the viral replication,clinical signs,and pathological responses observed in *** animal species should be tested to establish an appropriate animal model to study the disease pathology,transmission and evaluation of novel vaccine and drug candidates to treat coronavirus disease *** this context,the present review summarizes the recent progress in developing animal models for these two pathogenic viruses and highlights the utility of these models in studying SARS-associated coronavirus diseases.

关键词： Animal models SARS-Cov-1 SARS-Cov-2 COvID-19 Mice Hamster Non-human primates Pathogenesis Transmission Therapeutics