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Resequencing of 145 Landmark Cultivars Reveals Asymmetric Sub-genome Selection and Strong Founder Genotype Effects on Wheat Breeding in China

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Molecular Plant 2020年第12期13卷 1733-1751页

作者： Chenyang Hao Chengzhi Jiao Jian Hou Tian Li Hongxia Liu Yuquan Wang Jun Zheng Hong Liu Zhihong Bi Fengfeng Xu Jing Zhao Lin Ma Yamei Wang uzma majeed Xu Liu Rudi Appels Marco Maccaferri Roberto Tuberosa Hongfeng Lu Xueyong Zhang Key Laboratory of Crop Gene Resources and Germplasm Enhancement Ministry of Agriculture and Rural Affairs/The National Key Facility for Crop Gene Resources and Genetic Improvement/Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China Novogene Bioinformatics Institute Beijing 100083China AgriBio Centre for AgriBioscienceDepartment of Economic DevelopmentJobsTransportand Resources5 Ring RoadLa Trobe UniversityBundooraVIC 3083Australia Department of Agricultural and Food Sciences University of BolognaBolognaItaly

Controlled pedigrees and the multi-decade timescale of national crop plant breeding programs offer a unique experimental context for examining how selection affects plant *** than 3000 wheat cultivars have been registered,released,and documented since 1949 in *** this study,a set of 145 elite cultivars selected from historical points of wheat breeding in China were re-sequenced.A total of 43.75 Tb of sequence data were generated with an average read depth of 17.94x for each cultivar,and more than 60.92 million SNPs and 2.54 million InDels were captured,based on the Chinese Spring RefSeq genome *** years of breeder-driven selection led to dramatic changes in grain yield and related phenotypes,with distinct genomic regions and phenotypes tar-geted by different breeders across the *** are very clear instances illustrating how introduced Italian and otherforeign germplasm was integrated into Chinese wheat programs and reshaped the genomic landscape of local modern ***,the resequencing data also highlighted significant asymmetric breeding selec-tion among the three sub-genomes:this was evident in both the collinear blocks for homeologous chromosomes and among sets of three homeologous *** of more newly assembled genes in newer cultivars implied the potential value of these genes in *** and extended sharing of linkage disequilibrium(LD)blocks was highlighted among pedigree-related cultivars,in which fewer haplotype differences were *** or replacement of haplotypes from founder genotypes after generations of breeding was related to their breeding *** on the haplotype frequency changes in LD blocks of pedigree-related cultivars,we propose a strategy for evaluating the breeding value of any given line on the basis of the accumulation(pyramiding)of bene-ficial ***,our study demonstrates the influence of "founder genotypes" on the output of breeding effort

关键词： wheat breeding asymmetric selection founder genotype haplotype block

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Influence of Brownian Motion, Thermophoresis and Magnetic Effects on a Fluid Containing Nanoparticles Flowing over a Stretchable Cylinder

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Fluid Dynamics & Materials Processing 2024年第3期20卷 525-536页

作者： Aaqib majeed Ahmad Zeeshan Department of Mathematics The University of FaisalabadFaisalabad38000Pakistan Department of Mathematics and Statistics FBASInternational Islamic University IslamabadIslamabad44000Pakistan

The influence of Brownian motion and thermophoresis on a fluid containing nanoparticles flowing over a stretchable cylinder is *** classical Navier-Stokes equations are considered in a porous *** addition,the Lorentz force is taken into *** controlling coupled nonlinear partial differential equations are transformed into a system of first order ordinary differential equations by means of a similarity *** resulting system of equations is solved by employing a shooting approach properly implemented in *** evolution of the boundary layer and the growing velocity is shown graphically together with the related profiles of concentration and *** magnetic field has a different influence(in terms of trends)on velocity and concentration.

关键词： Mixed convection Brownian motion heat transfer porous surface velocity slip

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Road to recompensation:BavenoⅦcriteria and transjugular intrahepatic portosystemic shunt in liver cirrhosis

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World Journal of Gastroenterology 2024年第32期30卷 3743-3747页

作者： Muhammad Aarish Anis Ammara Abdul majeed Shahab Abid Department of Medicine Section of GastroenterologyAga Khan University HospitalSindhKarachi 74800Pakistan

Liver cirrhosis has long been considered a point of no return,with limited hope for ***,recent advancements,particularly the Baveno VII criteria and the utilization of transjugular intrahepatic portosystemic shunt(TIPS),have illuminated the concept of hepatic *** this editorial we comment on the article by Gao et al published in the recent *** editorial provides a comprehensive overview of the evolution of understanding cirrhosis,the criteria for recompensation,and the efficacy of TIPS in achieving *** discuss key findings from recent studies,including the promising outcomes observed in patients who achieved recompensation post-TIPS *** further research is needed to validate these findings and elucidate the mechanisms underlying recompensation,the insights presented here offer renewed hope for patients with decompensated cirrhosis and highlight the potential of TIPS as a therapeutic option in their management.

关键词： Decompensated hepatic cirrhosis Hepatic recompensation Transjugular intrahepatic portosystemic shunt Variceal bleeding Refractory ascites

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Test particles and quasiperiodic oscillations around Kiselev black hole with cloud of strings

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Chinese Physics C 2024年第5期48卷 293-308页

作者： Javlon Rayimbaev Uktambek Eshimbetov Bushra majeed Ahmadjon Abdujabbarov Alisher Abduvokhidov Bakhrom Abdulazizov Akram Xalmirzayev School of Mathematics and Natural Sciences New Uzbekistan UniversityMovarounnahr Str.1Tashkent 100000Uzbekistan School of Engineering Central Asian UniversityTashkent 111221Uzbekistan University of Tashkent for Applied Sciences Str.Gavhar 1Tashkent 100149Uzbekistan Institute of Fundamental and Applied Research National Research University TIIAMEKori Niyoziy 39Tashkent 100000Uzbekistan National University of Uzbekistan Tashkent 100174Uzbekistan Ulugh Beg Astronomical Institute Astronomy Str.33Tashkent 100052Uzbekistan Tashkent State Technical University Tashkent 100095Uzbekistan College of Electrical and Mechanical Engineering(CEME) National University of Sciences and TechnologyRawalpindiPakistan Andijan State University Universitet Str.129Andijan 170100Uzbekistan Namangan State University Boburshoh Str.161Namangan 160107Uzbekistan

In the present study,we investigate the dynamics of test particles around a Schwarzschild black hole surrounded by quintessence and immersed in a scalar string cloud *** start our study by defining the possible values of the quintessence and cloud of string parameters corresponding to the existence of the black hole horizon for fixed values of the parameters of the equation of state for dark *** also study the effects of the effective potential on the circular motion,energy,and angular momentum of the test particles together with the innermost stable circular orbits(ISCOs).We investigate the fundamental frequencies in the particle oscillations along stable circular *** relate the stability of the orbits to the Lyapunov exponent,and the chaotic behavior is studied ***,we apply the fundamental frequencies to describe quasiperiodic oscillations(QPOs)and find that,in the presence of both fields,low-frequency twin-peak QPOs are not *** addition,we obtain the constraint values for the string cloud parameter and mass of the black hole candidates located in the center of the microquasars GRO J1655-40 and GRS 1915+105 as well as the Milky Way galaxy.

关键词： quintessential field black holes string cloud quasiperiodic oscillations

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Enhancing the Decomposition of Paper Cups Using Galleria Mellonella and Eisenia Fetida

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Journal of Renewable Materials 2024年第2期12卷 349-367页

作者： Shadi Moqbel Habib Al-Ghoul Abd Al-majeed Al-Ghzawi Rami Mukbel Civil Engineering Department The University of JordanAmman11942Jordan Department of Chemistry Technical University of MunichMunichGermany Plant Production Jordan University of Science and TechnologyIrbid22110Jordan Basic Medical Veterinary Sciences Jordan University of Science and TechnologyIrbid22110Jordan

The composition of paper cups creates a challenge for the recycling industry,as the paperboard–plastic film composite is hard to ***,paper cups are sent to landfills or waste *** study explores the combined use of red worms(Eisenia fetida)and Greater wax moth(Galleria mellonella)in the biodegradation of paper *** study investigates the conditions and combinations that promote using Eisenia fetida and Galleria mellonella for degrading paper *** study considered the influence of environmental temperature,the presence of food waste,varying the number of Eisenia fetida worms,and the presence of a Galleria mellonella growth-slowing agent on the degradation *** achieve the study objectives,the study followed a quantitative *** study monitored the degradation of paper cup cuts that were placed in jars containing different combinations of Eisenia fetida worms,Galleria mellonella larvae,food waste,bedding material,and Galleria mellonella growth-slowing *** study found that the best operating temperature is *** study found that using food waste improves the performance of Eisenia fetida worms and Galleria mellonella larvae *** study found that adding a Galleria mellonella growth-slowing agent slightly enhances the degradation of the paper ***,a numerical model was obtained to simulate the paper cup degradation efficiency.

关键词： Paper cups resource recovery recycling circular economy Galleria mellonella Eisenia fetida

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Investigating and predicting the role of photovoltaic, wind, and hydrogen energies in sustainable global energy evolution

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Global Energy Interconnection 2024年第4期7卷 429-445页

作者： Mahmood Swadi Dheyaa Jasim Kadhim Mohamed Salem Firas Mohammed Tuaimah Ammar Sabri majeed Ali Jawad Alrubaie Department of Electrical Engineering College of EngineeringUniversity of BaghdadBaghdad 10001Iraq Libyan Authority for Scientific Research Tripoli 80045Libya School of Electrical and Electronic Engineering Universiti Sains Malaysia(USM)Nibong Tebal 14300PenangMalaysia Continuing Education Center University of BaghdadBaghdad 10001Iraq Al-Furat Al-Awsat Technical University AL-Mussaib Technical CollegeBabylonIraq

The global shift toward next-generation energy systems is propelled by the urgent need to combat climate change and the dwindling supply of fossil *** review explores the intricate challenges and opportunities for transitioning to sustainable renewable energy sources such as solar,wind,and *** transition economically challenges traditional energy sectors while fostering new industries,promoting job growth,and sustainable economic *** transition to renewable energy demands social equity,ensuring universal access to affordable energy,and considering community *** environmental benefits include a significant reduction in greenhouse gas emissions and a lesser ecological *** study highlights the rapid growth of the global wind power market,which is projected to increase from$112.23 billion in 2022 to$278.43 billion by 2030,with a compound annual growth rate of 13.67%.In addition,the demand for hydrogen is expected to increase,significantly impacting the market with potential cost reductions and making it a critical renewable energy source owing to its affordability and zero *** 2028,renewables are predicted to account for 42%of global electricity generation,with significant contributions from wind and solar photovoltaic(PV)technology,particularly in China,the European Union,the United States,and *** developments signify a global commitment to diversifying energy sources,reducing emissions,and moving toward cleaner and more sustainable energy *** review offers stakeholders the insights required to smoothly transition to sustainable energy,setting the stage for a resilient future.

关键词： Next energy Renewable energy Sustainability Environmental benefits Economic opportunities

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Natural Convection and Irreversibility of Nanofluid Due to Inclined Magnetohydrodynamics(MHD)Filled in a Cavity with Y-Shape Heated Fin:FEM Computational

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1505-1519页

作者： Afraz Hussain majeed Rashid Mahmood Sayed M.Eldin Imran Saddique S.Saleem Muhammad Jawad School of Energy and Power Engineering Jiangsu UniversityZhenjiang212013China Department of Mathematics Air UniversityIslamabad44000Pakistan Center of Research Faculty of EngineeringFuture University in EgyptNew Cairo11835Egypt Department of Mathematics University of Management and TechnologyLahore54770Pakistan Department of Mathematics University of SargodhaSargodha40100Pakistan Department of Mathematics College of ScienceKing Khalid UniversityAbha61413Saudi Arabia Faculty of Sciences The Superior UniversityLahore54000Pakistan

This study explains the entropy process of natural convective heating in the nanofluid-saturated cavity in a heated fin andmagnetic *** temperature is constant on the Y-shaped fin,insulating the topwall while the remaining walls remain *** walls are subject to impermeability and non-slip *** mathematical modeling of the problem is demonstrated by the continuity,momentum,and energy equations incorporating the inclined magnetic *** elucidating the flow characteristics Finite ElementMethod(FEM)is implemented using stable FE pair.A hybrid fine mesh is used for discretizing the *** and thermal plots concerning parameters are *** addition,a detailed discussion regarding generation energy by monitoring changes in magnetic,viscous,total,and thermal irreversibility is *** addition,line graphs are created for the u and v components of the velocity profile to predict the flow *** simulations assume the dimensionless representative of magnetic field Hartmann number Ha between 0 and 100 and a magnetic field inclination between 0 and 90 degrees.A constant 4% volume proportion of nanoparticles is employed throughout all scenarios.

关键词： Finite element method nanomaterials entropy MHD square cavity Y-fin

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Significance of the number of positive cervical lymph nodes in resected early T stage squamous cell carcinoma of the oral tongue

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中国口腔颌面外科杂志 2008年第B5期6卷 87-87页

作者： Hassan Iqbal Arif Jamshed Raza Hussain Rafay Azhar uzma majeed Department of Surgey Shaukat Khartum Memorial Hospital Lahore Pakistan Department of Radiation Oncology Shaukat Khartum Memorial Hospital Lahore Pakistan Department of Pathology Shaukat Khartum Memorial Hospital Lahore Pakistan

Purpose: Neck node metastasis in squamous cell carcinoma of the oral tongue (SCCOT) is a recognized prognostic factor。However, the significance between number of positive nodes and survival is still not defined。This study was conducted to determine the impact of number of pathologically positive nodes on survival in patients with T1-2 SCCOT。Methods: Between August 2004 and September 2007, 50 patients with Tl-2 SCCOT treated with curative surgery at Shaukat Khanum Memorial Cancer Hospital and Research Centre were analyzed retrospectively。M 50%:F 50% (range 15—68 years)。All patients underwent partial glossectomy with neck dissection。Neck dissection was ipsilateral in 46 patients (92%) and bilateral in 4 patients (8%)。Forty four (88%) percent had post operative radiotherapy。Patients were divided in to 3 subgroups to determine the significance of number of positive nodes on survival: node negative (GroupⅠ), 1 - 3 positive nodes (GroupⅡ) and 4 or more nodes (Group III)。Results: AJCC stage was pTlpN0 31%, pT1pN+ 18%, pT2pN0 27% and pT2pN+ 24%。A total of 2230 cervical lymph nodes were analysed。Number of nodes in levelⅠ,Ⅱ,Ⅲ,ⅣandⅤwas 387, 721,465, 562 and 25 respectively。The mean and median number of nodes removed was 44 and 41 respectively。Twenty nine (58%) patients had NO (GroupⅠ), 15 (30%) patients had 1 to 3 positive lymph nodes (GroupⅡ) and 6 (12%) had 4 or more positive cervical lymph nodes(GroupⅢ)。Kaplan Meier estimate for 3 year disease free survival (DFS) for GroupⅠ,ⅡandⅢwas 71%, 48% and 0% respectively (P=-0.004)。DFS for the whole group was 57%。Conclusion: Increasing number of pathologically positive cervical lymph node metastasis has an inverse influence on survival。In patients with 4 or more positive nodes aggressive adjuvant post operative treatment with radiation and chemotherapy should be considered as the prognosis is poor。

关键词：口腔癌鳞状细胞癌颈部淋巴结点治疗方法

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Comparative analysis of SIMILAR to RCD ONE(SRO)family from tetraploid cotton species and their diploid progenitors depict their significance in cotton growth and development

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Journal of Cotton Research 2024年第1期7卷 45-57页

作者： SHABAN Muhammad TABASSUM Riaz RANA Iqrar Ahmad ATIF Rana Muhammad AZMAT Muhammad Abubakkar IQBAL Zubair majeed Sajid AZHAR Muhammad Tehseen Department of Plant Breeding and Genetics University of Agriculture FaisalabadSub-Campus BurewalaVehari 61010Pakistan Department of Chemistry and Biochemistry University of AgricultureFaisalabad 38400Pakistan Centre of Agricultural Biochemistry and Biotechnology University of AgricultureFaisalabad 38400Pakistan Department of Plant Breeding and Genetics University of AgricultureFaisalabad 38400Pakistan Precision Agriculture and Analytics Lab National Centre in Big Data and Cloud ComputingCentre for Advanced Studies in Agriculture and Food SecurityUniversity of Agriculture FaisalabadFaisalabad 38400Pakistan Department of Plant Pathology University of CaliforniaDavisCA 95616USA State Key Laboratory of Cotton Biology Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyangHenan 455000China Federal Seed Certification and Registration Department Ministry of National Food Security and ResearchIslamabad 44090Pakistan School of Agriculture Sciences Zhengzhou UniversityZhengzhou 450000China

Background SRO(Similar to RCD1)genes family is largely recognized for their importance in the growth,develop-ment,and in responding to environmental ***,genome-wide identification and functional characteri-zation of SRO genes from cotton species have not been reported so *** A total of 36 SRO genes were identified from four cotton *** analysis divided these genes into three groups with distinct *** and chromosomal distribution analysis indicated uneven distribu-tion of GaSRO,GrSRO,GhSRO,and GbSRO genes on A2,D5 genomes,Gh-At,Gh-Dt,Gb-At,and Gb-Dt subgenomes,*** duplication analysis revealed the presence of six duplicated gene pairs among GhSRO *** promoter analysis,several elements responsive to the growth,development and hormones were found in GhSRO genes,implying gene induction during cotton growth and *** miRNAs responsive to plant growth and abiotic stress were predicted to target 12 GhSRO ***-specific expression profiling demonstrated the roles of GhSRO genes in one or more *** addition,specific expression pattern of some GhSRO genes dur-ing ovule development depicted their involvement in these developmental *** The data presented in this report laid a foundation for understanding the classification and functions of SRO genes in cotton.

关键词： Cotton SRO miRNAs Gene duplications Gene expression Ovule development

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Enhancement in Bioavailability of CurCousin^®, A Minor Metabolite from Curcuma longa by Addition of BioPerine^® —A Pharmacokinetic Study

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Journal of Biosciences and Medicines 2024年第2期12卷 282-293页

作者： Muhammed majeed Kalyanam Nagabhushanam Sarang Bani Anjali Pandey Smitha Thazhathidath Sami-Sabinsa Group Limited Bengaluru India Sabinsa Corporation New Jersey USA

In recent years, metabolic syndrome has been a growing health concern across the world. The role of nutraceuticals and functional foods in this area has a significant place due to the adverse effects of contemporary modes of treatment. CurCousin® is a nutritional ingredient containing bioactive Calebin A, (analog of Curcumin) with self-affirmed GRAS status. CurCousin® has been a clinically studied dietary supplement ingredient with a positive impact on body weight, lipid levels and metabolic health. Bioenhancers play an important role in increasing the bioavailability of the active in turn enhancing efficacy as well as reducing the dosage required to achieve the therapeutic effect. This study investigated the possible pharmacokinetic interaction between CurCousin® at two different doses (2.25 and 4.5 mg/kg) in the presence and absence of BioPerine® (0.27 mg/kg), a natural bioenhancer in Sprague-Dawley rats. The results revealed that the addition of BioPerine® into CurCousin® (2.25 mg/kg) half the dose when administered enhances the bioavailability and was equipotent to CurCousin® (4.5 mg/kg) double the dose without BioPerine®. Thus, leading to future clinical studies to evaluate its improved pharmacological efficacy as well as reduced therapeutic dosage.

关键词： Metabolic Health Bioavailability Pharmacokinetics CurCousin® BioPerine® Calebin A

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