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Peripapillary and macular vascular densities in healthy,ocular hypertensive,and different stages of glaucomatous eyes

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2018-2026页

作者： Caner Ozturk Sirel Gur Gungor umit eksioglu Almila Sarıgul Sezenoz Meric Colak Comparison of vascular densities in glaucoma patients 1Department of Ophthalmology Minister of Health Hitit University Erol Olcok Education and Research HospitalCorum 19030Turkey Department of Ophthalmology Baskent UniversityFaculty of MedicineAnkara 06170Turkey Department of Biostatistics Baskent UniversityFaculty of MedicineAnkara 06300Turkey

AIM:To investigate vascular changes in different stages of glaucoma and to evaluate the role of optical coherence tomography angiography(OCTA)in the early diagnosis of ***:Glaucoma patients and healthy controls(n=29 eyes)were investigated in this cross-sectional comparative *** patients were grouped as ocular hypertension(n=44 eyes),preperimetric glaucoma(PPG;n=32 eyes),early glaucoma(EG;n=35 eyes),moderate stage glaucoma(MG;n=36 eyes),and advanced glaucoma(AG;n=35 eyes).Peripapillary and macular vascular densities(VDs)of all participants were compared and correlations of VDs and retinal nerve fiber layer thickness(RNFLT),ganglion cell analysis(GCA),and visual field(VF)tests were *** under the receiver operation characteristic curves(AUC)of the peripapillary and macular VD parameters were ***:VD values decreased with the progression of *** peripapillary and macular VD parameters of PPG and EG groups were lower than healthy controls(P<0.001).There was no significant difference in RNFLT between the PPG and EG groups,but most peripapillary and macular VDs were found to be lower in EG group than in PPG group(P<0.05).In most disease group,VDs were significantly correlated with OCT parameters(P<0.001)and VF index(P<0.05).There were no significant correlations between VF and RNFLT indices in the AG group,but significant correlations were found between VF and VD values(P<0.05).AUC for discriminating between healthy and glaucomatous eyes were highest in whole image peripapillary VD(AUC:0.865,0.929,and 0.986,respectively in EG,MG,and AG groups).CONCLUSION:OCTA can be used in the early diagnosis of glaucoma and can be useful in follow-up of the advanced *** cases where limitations or suspicions in structural and functional tests are present,OCTA can be used as a supportive diagnostic test,both in EG and AG.

关键词： glaucoma optical coherence tomography angiography vascular density early diagnosis

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Prediction of Damping Capacity Demand in Seismic Base Isolators via Machine Learning

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Computer Modeling in Engineering & Sciences 2024年第3期138卷 2899-2924页

作者： Ayla Ocak umit Isıkdag Gebrail Bekdas Sinan Melih Nigdeli Sanghun Kim ZongWoo Geem Department of Civil Engineering Istanbul University-CerrahpasaIstanbul34320Turkey Department of Informatics Mimar Sinan Fine Arts UniversityIstanbul34427Turkey Department of Civil and Environmental Engineering Temple UniversityPhiladelphiaPA19122USA Department of Smart City Gachon UniversitySeongnam13120Korea

Base isolators used in buildings provide both a good acceleration reduction and structural vibration control *** base isolators may lose their damping capacity over time due to environmental or dynamic *** deterioration of them requires the determination of the maintenance and repair needs and is important for the long-termisolator *** this study,an artificial intelligence prediction model has been developed to determine the damage and maintenance-repair requirements of isolators as a result of environmental effects and dynamic factors over *** the developed model,the required damping capacity of the isolator structure was estimated and compared with the previously placed isolator capacity,and the decrease in the damping property was tried to be *** this purpose,a data set was created by collecting the behavior of structures with single degrees of freedom(SDOF),different stiffness,damping ratio and natural period isolated from the foundation under far fault *** data is divided into 5 different damping classes varying between 10%and 50%.Machine learning model was trained in damping classes with the data on the structure’s response to random seismic *** a result of the isolator behavior under randomly selected earthquakes,the recorded motion and structural acceleration of the structure against any seismic vibration were examined,and the decrease in the damping capacity was estimated on a class *** performance loss of the isolators,which are separated according to their damping properties,has been tried to be determined,and the reductions in the amounts to be taken into account have been determined by *** the developed prediction model,using various supervised machine learning classification algorithms,the classification algorithm providing the highest precision for the model has been *** the results are examined,it has been determined that the damping of the isolator structure with the

关键词： Vibration control base isolation machine learning damping capacity

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Ensemble for evaluating diagnostic efficacy of non-invasive indices in predicting liver fibrosis in untreated hepatitis C virus population

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World Journal of Methodology 2024年第3期14卷 90-105页

作者： Navneet Kaur Gitanjali Goyal Ravinder Garg Chaitanya Tapasvi umit Demirbaga Department of Biochemistry Guru Gobind Singh Medical College and HospitalFaridkot 151203PunjabIndia Department of Biochemistry All India Institute of Medical SciencesBathinda 151005PunjabIndia Department of Medicine Guru Gobind Singh Medical College and HospitalBaba Farid University of Health SciencesFaridkot 151203PunjabIndia Department of Radiodiagnosis Guru Gobind Singh Medical College and HospitalBaba Farid University of Health SciencesFaridkot 151203India Department of Computer Engineering Bartin UniversityBartin 74100Türkiye Department of Medicine University of CambridgeCambridge CB20QQUnited Kingdom European Bioinformatics Institute Wellcome GenomeCambridge CB101SDUnited Kingdom

BACKGROUND Hepatitis C virus(HCV)infection progresses through various phases,starting with inflammation and ending with hepatocellular *** are several invasive and non-invasive methods to diagnose chronic HCV *** invasive methods have their benefits but are linked to morbidity and ***,it is important to analyze the potential of non-invasive methods as an *** wave elastography(SWE)is a non-invasive imaging tool widely validated in clinical and research studies as a surrogate marker of liver *** fibrosis determination by invasive liver biopsy and non-invasive SWE agree closely in clinical studies and therefore both are gold *** To analyzed the diagnostic efficacy of non-invasive indices[serum fibronectin,aspartate aminotransferase to platelet ratio index(APRI),alanine aminotransferase ratio(AAR),and fibrosis-4(FIB-4)]in relation to *** have used an Artificial Intelligence method to predict the severity of liver fibrosis and uncover the complex relationship between non-invasive indices and fibrosis *** We have conducted a hospital-based study considering 100 untreated patients detected as HCV positive using a quantitative Real-Time Polymerase Chain Reaction *** performed statistical and probabilistic analyses to determine the relationship between non-invasive indices and the severity of *** also used standard diagnostic methods to measure the diagnostic accuracy for all the *** The results of our study showed that fibronectin is a highly accurate diagnostic tool for predicting fibrosis stages(mild,moderate,and severe).This was based on its sensitivity(100%,92.2%,96.2%),specificity(96%,100%,98.6%),Youden’s index(0.960,0.922,0.948),area under receiver operating characteristic curve(0.999,0.993,0.922),and Likelihood test(LR+>10 and LR-200),AAR(>1),APRI(>3),and FIB-4(>4)were all strongl

关键词： Hepatitis C virus Non-invasive biomarkers Shear wave elastography Fibronectin Bayesian network Machine learning Liver fibrosis

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Assessment Method of Offshore Wind Resource Based on Multi-dimenssiional Indexes System

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 76-87页

作者： Xiaomei Ma Yongqian Liu Jie Yan Shuang Han Li Li Hang Meng Muhammet Deveci Konstanze Kolle umit Cali the State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources(NCEPU) School of New EnergyNorth China Electric Power UniversityBeijing 102206China School of Physical and Electronic Information Engineering Qinghai Normal UniversityXiningQinghai 810016China State Key Laboratory of Alternate Electrical Power System with Renewable Energy Sources(NCEPU) School of New EnergyNorth China Electric Power UniversityBeijing 102206China the Royal School of Mines Imperial College London.London SW72AZUKand also with Department of Industrial EngineeringTurkish Naval AcademyNational Defence University34940IstanbulTurkey Department of Energy Systems SINTEF Energy ResearchTrondheimNO-7034 Norway Department of Electric Power Engineering Norwegian University of Science and TechnologyTrondheimNO-7491 Norway

Traditional assessment indexes could not fully describe offshore wind resources,for the meteorological properties of offshore are more complex than *** a result,the uncertainty of offshore wind power projects would be increased and final economic benefits would be ***,a study on offshore wind resource assessment is carried out,including three processes of“studying data sources,conducting multidimensional indexes system and proposing an offshore wind resource assessment method based on analytic hierarchy process(AHP).First,measured wind data and two kinds of reanalysis data are used to analyze the characteristics and reliability of data ***,indexes such as effective wind speed occurrence,affluent level occurrence,coefficient of variation,neutral state occurrence have been proposed to depict availability,richness,and stability of offshore wind resources,*** with existing parameters(wind power density,dominant wind direction occurrence,water depth,distance to coast),a multidimensional indexes system has been built and on this basis,an offshore wind energy potential assessment method has been ***,the proposed method is verified by the annual energy production of five offshore wind turbines and practical operating data of four offshore wind farms in *** study also compares the ranking results of the AHP model to two multi-criteria decision making(MCDM)models including weighted aggregated sum product assessment(WASPAS)and multi-attribute ideal real comparative analysis(MAIRCA).Results show the proposed method gains well in practical engineering applications,where the economic score values have been considered based on the offshore reasonable utilization hours of the whole life cycle in China.

关键词： Annual energyproduction aatmospheric stability data sources offshore wind resource wind power density

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An Examination ofthe Impact of Game-Based Geometric Shapes Education Software Usage on the Education of Students With Intellectual Disabilities

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ECNU Review of Education 2022年第4期5卷 761-783页

作者： umit Demir Department of Computer Technologies Canakkale Onsekiz Mart UniversityCanakkale 17020Turkey

Purpose:This study aims to research the impact of the e-learning environment,in which gamebased education software was used,on the learning of students with intellectual ***/Approach/Methods:The study group consisted of 34 students with intellectual disabilities studying at a special education vocational school in Canakkale,*** this study,the true experimental method was *** 5 weeks,the experimental group received blended learning that was supported by the usage of a game-based education software designed by the researcher,which includes interactive educational game *** the same time,control group students only received the teaching process in the classroom with the traditional teaching *** attitude scale and an achievement test were used fordata ***:The analysis of the findings showed that there was a significant increase between precourse and post-course attitudes and academic achievement scores of the *** wasn't a significant difference between pre-course and post-course attitudes and academic achievement scores according to the gender and academic achievement ***'academic achievement and attitude post-test scores were higher than females'*** having upper daily mobile devices usage experience had higher post-test and academic achievement scores than students havinglowerdaily mobile devices usage experience.

关键词： Game-based education geometry education special education

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Hybrid q-Rung Orthopair Fuzzy Sets Based CoCoSo Model for Floating Offshore Wind Farm Site Selection in Norway

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CSEE Journal of Power and Energy Systems 2022年第5期8卷 1261-1280页

作者： Muhammet Deveci Dragan Pamucar umit Cali Emre Kantar Konstanze Kolle John O.Tande Department of Industrial Engineering Turkish Naval AcademyNational Defence UniversityIstanbul 34940Turkey Department of Operations Research and Statistics Faculty of Organizational SciencesUniversity of BelgradeBelgradeSerbia Department of Electric Power Engineering Norwegian University of Science and TechnologyTrondheim NO-7491Norway Department of Electric Power Technology SINTEF Energy ResearchTrondheim NO-7491Norway Department of Energy Systems SINTEF Energy ResearchTrondheim NO-7034Norway

Unlocking offshore wind farms’high energy generation potential requires a comprehensive multi-disciplinary analysis that consists of intensive technical,economic,logistical,and environmental *** wind energy projects have high investment volumes that make it essential to conduct extensive site selection to ensure feasible investment decisions that reduce the potential financial *** on the scenario and circumstances,a ranking of alternative offshore wind energy projects helps to prioritise the investment *** algorithms based on expert knowledge can support the prioritisation and thus alleviate the work load for investment decisions in the *** case study considered here is to find the best site for a floating offshore wind farm in Norway from four pre-selected alternatives:Utsira Nord,Stadthavet,Froyabanken,and Trana *** propose a hybrid decisionmaking model as a combined compromised solution(CoCoSo)based on the q-rung orthopair fuzzy sets(q-ROFSs)including the weighted q-rung orthopair fuzzy Hamacher average(Wq-ROFHA)and the weighted q-rung orthopair fuzzy Hamacher geometric mean(Wq-ROFHGM)*** this model,the q-ROFSs based full consistency method(FUCOM)is introduced as a new methodology to determine the weights of the decision *** results of the proposed model show that the best site among the investigated four alternatives is A1:Utsira Nord.A sensitivity analysis has verified the stability of the proposed decision-making model.

关键词： Decision-making q-rung orthopair fuzzy sets Fuzzy hamacher site selection offshore wind farm FUCOM

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Contemporary minimal invasive surgical management of stones in children

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Asian Journal of Urology 2023年第3期10卷 239-245页

作者： Rasim Guzel umit Yildirim Kemal Sarica Department of Urology Medistate Kavacık HospitalIstanbulTurkey Department of Urology Medical SchoolKafkas UniversityKarsTurkey Department of Urology Medical SchoolBiruni UniversityIstanbulTurkey

Objective:Pediatric urolithiasis has been more common over the past 20 years,and urologists have unique challenges in managing it surgically because this particular demographic is recognized as one of the high-risk categories for stone *** this reality,care focuses on maintaining renal function,achieving total stone-free status,and most importantly avoiding stone *** this presented article,we aimed to make a comprehensive review of the current minimally invasive treatment of pediatric kidney stone ***:We evaluated the results of 74 studies following a comprehensive PubMed search till February *** article was written by making use of current urology ***:Considering the reported occurrence of metabolic issues in up to 50%of cases in addition to the anatomic anomalies(about 30%of cases),the treatment of pediatric urolithiasis necessitates a full metabolic and urological examination on an individual *** management of metabolic imbalances and obstructive diseases is *** addition to encouraging proper fluid consumption,it is advisable to improve urine volume and consider using medical therapeutics to raise urinary citrate *** location,content,and size of the stone(s),the morphology of the collecting system,the presence of urinary tract infection,as well as the presence of any obstruction,should all be taken into consideration while deciding on the best surgical ***:All modern endourological methods are now used in the safe and efficient care of pediatric urolithiasis as a consequence of the obvious advancements in instrument technology and expanding expertise derived from adult *** minimally invasive procedures,such as ureterorenoscopy and percutaneous nephrolithotomy,require more expertise and can be successfully applied with careful management for an excellent stone-free rate with minimal *** these procedures,shock wave lithotripsy is still the first ch

关键词： Urinary calculi Shock wave lithotripsy Percutaneous nephrolithotomy Ureteroscopy

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Recent progress of electromagnetic wave absorbers: A systematic review and bibliometric approach

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ChemPhysMater 2023年第3期2卷 197-206页

作者： Yuksel Akinay umit Gunes BektaşÇolak Tayfun Cetin Mining Engineering Van Yuzuncu Yil UniversityVan 65080Turkey Naval Architecture and Marine Engineering Yildiz Technical UniversityBesiktasIstanbul 34349Turkey Natural Sciences Faculty Physics DepartmentGebze Technical UniversityGebz 41400Turkey Yuksekova Vocational High School Hakkari UniversityHakkari 30110Turkey

The electromagnetic wave absorption capabilities of an absorber depend on its dielectric and magnetic compo- nents, which determine its interfacial polarization, conductivity loss, magnetic loss, and other such mechanisms. In this study, a comprehensive review of the electromagnetic wave and material interaction was conducted. Moreover, for a better understanding of the trends and evolutionary developments in the study of the electro- magnetic wave absorber, 23300 documents dated between 1990 and 2020 were examined, which were obtained from Scopus using the keywords of “electromagnetic wave absorption ”and “microwave absorption ”. The data search in Scopus was conducted using the related keywords in the search bar for titles and abstracts. These results demonstrate that the majority of research regarding electromagnetic wave absorbers was conducted in China, which was followed by the United States. The number of published documents regarding the electromagnetic wave absorption field significantly increased between 1990 and 2020;these documents were mostly published as journal articles. With respect to the journal activity, the most productive journal was the “Journal of Alloys and Compounds ”, with a total of 592 articles. In addition, graphene and titanium dioxide were determined to be the materials that were most studied in the field of electromagnetic wave absorption.

关键词： Electromagnetic wave absorption Microwave absorption Bibliometric approach Reflection loss Composites

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Clinical value of phenylephrine testing in the upper and lower eyelids of patients with aponeurotic and congenital eyelid ptosis

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International Journal of Ophthalmology(English edition) 2022年第9期15卷 1444-1452页

作者： Ozgun Melike Gedar Totuk Meltem Guzin Altinel Ayse Yagmur Kanra umit Aykan Atakoy Dunyagoz Hospital BakirkoyIstanbul 34158Turkey Department of Ophthalmology Fatih Sultan Mehmet Training and Research HospitalAtasehirIstanbul 34752Turkey Department of Ophthalmology Sisli Hamidiye Etfal Training and Research HospitalSariyerIstanbul 34453Turkey Etiler Dunyagoz Hospital BesiktasIstanbul 34337Turkey

·AIM:To characterize the phenylephrine test in aponeurotic and congenital eyelid ptosis,to determine the appropriate timing of the phenylephrine test,and to assess the responses of the upper and lower eyelids.·METHODS:This was a retrospective analysis of 140 eyes of 87 patients(mean age 52.29±16.45 y;22 males,65 females)with upper eyelid *** 88.6%had aponeurotic and 11.4%had congenital *** the evaluation of the responses of the upper and lower eyelids to topical 2.5%phenylephrine,the scleral show height,the marginal reflex distance(MRD)between the inferior margin of the upper eyelid and pupillary light reflex(MRD1),and between the central portion of the lower eyelid and pupillary light reflex(MRD2)were measured at the 2^(nd),5^(th),and15^(th)*** changes of MRD1 and MRD2 with time(ΔMRD1 andΔMRD2)were evaluated.·RESULTS:The mean MRD1,*** scleral show heights increased within 5 min after testing,remaining largely stable between the 5^(th)-15^(th)*** percentage of eyes with a greater response in MRD1 increased with increased severity of ptosis(P<0.05).Eyes with aponeurotic ptosis were more responsive to phenylephrine testing than congenital *** mild ptosis group had lower scleral show measurements and higherΔMRD2 ***ΔMRD1 andΔMRD2 values were poorly correlated in all measurement times.·CONCLUSION:Performing the phenylephrine test 5 min after instilling the reagent is adequate to assess the maximum response of the upper and lower *** upper and lower eyelid responses in phenylephrine testing are poorly ***,theΔMRD2 is related with baseline scleral show degree that may be a postoperative predictive *** studies are necessary to determine the relationship between the responses of the lower eyelids to phenylephrine testing.

关键词： eyelid ptosis phenylephrine testing scleral show aponeurotic ptosis congenital ptosis

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A New Fluorescent Chemosensor for Selective and Sensitive Detection of Mn²⁺ in Acidic Medium

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Advances in Biological Chemistry 2022年第5期12卷 161-170页

作者： Ay umit Department of Chemistry Kocaeli University Kocaeli Turkey

Recently, fluorescent sensors have attracted considerable attention in their sensitive and selective determination of heavy metal ions in the aqueous acidic medium due to their advantages such as low cost and easy handling. In this study, the bathocuproine (BCP) compound was used as a fluorescent chemosensor. The selectivity and sensitivity of BCP have been investigated against some metal ions of biological and environmental importance. The results obtained from the ultraviolet-visible region (UV-vis.) and the fluorescence spectroscopy experiments revealed that the BCP sensor showed selectivity and sensitivity only to Manganese (II) ions in the experimental conditions studied. In addition, the binding stoichiometry of BCP and Mn2+ was determined to be 1:1 by the Benesi-Hildebrand method.

关键词： Fluorescent Chemosensor Mn2+ Fluorescence Quenching Selectivity

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