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The Effect of Age on Male Infertility in Gabon

Advances in Reproductive Sciences 2023年第4期11卷 127-139页

作者： Makoyo Komba Opheelia Lionel Wildy Moungala ulysse minkobame Pamphile Assoumou Alain Boulende Jean Francois Meye Departement of Obstetrics and Gynaecology Mother and Child University Hospital of Libreville Libreville Gabon Androcryos Andrology Laboratory Departement of Obstetrics and Gynaecology University of Witwatersand Johannesburg South Africa Reproductive Biology Laboratory Department of Obstetrics and Gynaecology Mother and Child University Hospital of Libreville Libreville Gabon

Background: Male age significantly affects semen parameters. However, there is no evidence on the impact of aging on semen quality in men residing in Libreville, Gabon. Objective: To determine the effects of age on semen quality of patients visiting the Reproductive Laboratory at the Academic Hospital Mère Enfant located in Libreville, Gabon. Methods: This descriptive and prospective study was performed between the 1st of October 2021 and 30st of September 2022. This study involved patients who had semen analysis as part of fertility check-up. Semen analysis was performed following the World Health Organization, 2010 guidelines. Semen parameters such as volume, leucocytes count, sperm concentration, sperm motility, norml morphology and vitality were used in the current study. Descriptive statistics were performed. The Chi-square test and the Fisher test were used as statistical tools for the analysis of data. The ROC curve was used to illustrate the data. Results: A total of 148 patients were included in the study. Male infertility prevalence was 77.03%. The average age was 41 years with minimum and maximum of 24 and 61 years respectively. Secondary infertility was predominant (66.9%). Patients displaying asthenozoospermia (22.3%) followed by those displaying oligoasthenozoospermia (OAT) isolated (1.4%) or not (11.6%) were the most frequent semen parameter abnormalities. Men aged more than 45 years were 4.4 times likely to have abnormal semen parameters. Odd = 4.4 (IC 95% = [3.3 - 14.7]). Staphylococcus haemolyticus infection was more prevalent. Conclusion: Male age was found to significantly influence semen quality.

关键词： Gabon Infertility Semen Analysis

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LARCs after unsafe abortion in Libreville (Gabon): Women accept quickly but the time interval for the insertion is longer than that of injectable contraceptives

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Open Journal of Obstetrics and Gynecology 2014年第1期4卷 23-27页

作者： Sosthène Mayi-Tsonga Jacques Bang Ntamack Boniface Sima-Ole Pamphile Assoumou Obiang ulysse minkobame Doris Ngouafo Department of Obstetrics and Gynecology of University Hospital of Libreville Gabon Africa Faculty of Health Sciences of Libreville Gabon Africa

Objectives: To determine the percentage of women who accepted a LARC after abortion, specify the interval time for the insertion of the LARC and compare such interval time with that of injectable and oral contraceptives. Patients and Methods: This is a prospective, descriptive and comparative study conducted in Libreville (Gabon), from February 1, 2013 to August 31, 2013. After receiving post-abortion care (PAC), all patients with stable general states were counseled about three types of contraceptive methods: combined oral contraceptive pills, LARCs (Jadelle? implants, Copper IUDs) and injectable Medroxyprogesterone Acetate (DMPA). Results: 231 women received PAC and among them 215 (93%) wanted to use one of the three proposed contraceptive methods. At the end of the study, only 193 women (89.7%) used contraception and 22 others (10.3%) abandoned their intentions. LARCs were used by 31 (16.0%) women. The average period for the insertion of LARCs was 15.4 ± 15.5 days with extremes of 1 to 53 days. This period for the insertion of LARCS was significantly longer than that of other methods (p < 0.001). LARCs were inserted more often after the 2nd day than immediately (same day) with a highly significant difference (p < 0.0001). Conclusion: LARCs could constitute an appropriate approach to reducing unintended pregnancies in Gabon. However, in order to increase their rates of use, it is necessary to improve women awareness.

关键词： Unsafe Abortion Contraception LARC Period for the Insertion of LARCs Gabon

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Causes of Infertility of Couples Residing in Libreville

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Advances in Reproductive Sciences 2024年第1期12卷 75-82页

作者： Opheelia Makoyo Komba ulysse minkobame Pamphile Assoumou Reteno Retno Elsy Ntsame Anouchka Mewi Jacques Albert Bang Ntamack Jean François Meye Département de gynécologie obstétrique Université des sciences de la santé d’Owendo Libreville Gabon

Introduction: According to the World Health Organization, globally one in six people experience infertility in their lifetime. Infertility is considered as a major and global public health issue. In most cases, women bear the burden of infertility to protect the male ego. Although men and women are equally likely to have fertility problems. The aim of this study was to identify the causes of infertility of couples residing in Libreville. Patients and Methods: This was a retrospective descriptive study performed over 2 years, from 1st January 2021 to 31st December 2022. Data was obtained from 162 couples attending the assisted reproduction department of the mother and child hospitals in Libreville. Statistical analysis was done using IBM SPSS Statistics version 22.0 software. Results: During the study period, 28.5% of couples could afford IVF treatment. The average for woman age was 39.1 ± 4.06 while the average age for male patients was 41.53 ± 7.08 years with minimum and maximum age of 34 et 66 years. More than half (58.6%) of female partners were employed in the public sector. Half of the male partners (50%) were employed in the private sector. The median duration of infertility was 6 years. Approximately 49.4% of couples were diagnosed with primary infertility. The most common causes of infertility in female patients were Fallopian tubes obstruction (53.2%), uterine factors (24.2%) and hormonal problems (19.6%). With regards to male factors infertility, testicular causes were predominant (53.6%). Oligoasthenoteratozoospermia were the major semen abnormalities (55.7%) found after semen evaluation. Both male and female partners were sub-fertile in 47.5% of cases. Unexplained infertility was found in 11% of couples. Conclusion: This study showed that the diagnostic of infertility faced by couples residing in Libreville should involve both male and female partner.

关键词： Epidemiology Gabon Infertility

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Conservative Treatment of Breast Cancer and Oncoplasty at the Teaching Hospital Mother and Child of Jeanne Ebori Foundation in Libreville (Gabon)

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Open Journal of Obstetrics and Gynecology 2023年第10期13卷 1747-1758页

作者： Assoumou Obiang Pamphile minkobame ulysse Makoyo Opheelia Eya’Ama Robert Dikongo Wilson Mewie Anouchka Ntsame Elsy Juvette Minto’o Junior Bang Jacques Albert Meye Jean François Department of Obstetrics Gynecology Faculty of Medicine of Libreville University of Health Sciences (USS) Libreville Gabon

Introduction: Breast cancer is currently the most common malignant tumour in women worldwide. Objective: To evaluate conservative treatment of breast cancer and oncoplasty at the teaching hospital Mother and Child of Jeanne Ebori Foundation (CHUMEFJE). Patients and methods: This is an observational, descriptive study, which took place from August 2019 to December 2021 at CHUMEFJE. Data were collected using patients’ medical records, and operative and pathological anatomy reports. Results: Conservative treatment and oncoplasty were performed in 12 (34.2%) patients. Of these patients, 8 (66.7%) benefited from an external technique and 2 (16.7%) from a pamectomy. Post-operative complications were dominated by lymphocele in 5 (41.6%) patients. Ten (83.3%) patients were satisfied with the post-operative aesthetic result. At the time of updating the records, 1 (8.3%) patient had died and 11 (91.7%) were alive. Conclusion: Conservative treatment and oncoplasty are giving satisfactory results at the CHUMEFJE in Libreville.

关键词： Breast Cancer Conservative Treatment Oncoplasty Aesthetics Satisfaction

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SHER Grade IIIb Placenta Abruptio Complicating Severe Superimposed Pre-Eclampsia at 19 WA: A Case Report

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Open Journal of Obstetrics and Gynecology 2023年第9期13卷 1516-1522页

作者： ulysse minkobame Zaga Minko Opheelia Makoyo Komba Pamphile Assoumou Obiang Irenée Edzo Mvono Elsy Ntsame Mezui Junior Minto’o Jacques Albert Bang Ntamack Jean François Meye Department of Gynecology Obstetrics Health Science’s University Libreville Gabon

The placenta abruptio is an extremely serious pathology which involves the maternal-fetal prognosis. We report the case of a 19-year-old patient who consulted for abdominopelvic pain associated with heavy vaginal bleeding on 19SA in a context of arterial hypertension. The symptomatology suddenly worsened with the onset of hemorrhagic shock, which prompted an emergency hysterotomy. The diagnosis of placenta abruptio grade III b of SHER was evoked. Uterine atony was objectified intraoperatively and uterine compression by the B-Lynch technique was performed. The evolution of the patient was favorable after a stay of 5 days in intensive care.

关键词： Added Preeclampsia Placenta Abruptio 19 Weeks Uterine Plication

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End-of-Pregnancy Monitoring at CHUMEFJE through the Functional Investigation Centre (FIC) in 2022

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Open Journal of Obstetrics and Gynecology 2024年第1期14卷 186-192页

作者： ulysse Pascal minkobame Zaga Minko Opheelia Makoyo Komba Pamphile Assoumou Obiang Anouchka Mewie Lendzinga Elsy Ntsame Mezui Irenee Edzo Mvono Jacques Albert Bang Ntamack Jean François Meye Department of Obstetrics and Gynaecology University of Health Sciences Libreville Gabon

Introduction: The end of pregnancy is a high-risk period for both mother and foetus. Rigorous monitoring can prevent complications before delivery. Materials and Method: We conducted a descriptive cross-sectional observational study. It took place in the delivery room of the Teacher hospital Mother and Child of Jeanne Ebori Fondation from the 01 October 2020 to 01 October 2021. All patients followed at the Functional Investigation Centre (FIC) of the CHUMEFJE and who gave birth in that same hospital were included. Data were collected on the basis of pregnancy diaries, the fic register and delivery room registers. They were analysed using SPSS Statistical Software. Results: During the period of our study, 4086 parturients arrived in the delivery room. Of these, 150 were followed up at the FIC, giving a prevalence of 3.7%. The majority of parturients (48%) had only one prenatal contact. 6 (4%) patients underwent pelvic scans, and 4 (2.6%) presented with a narrowed pelvis. A vaginal delivery was performed in 80% of cases, and of the caesarean sections, 9 (30%) could be scheduled. The maternal prognosis was marred by one post-partum complication of hypertension, and newborns with poor adaptation to life outside the womb accounted for 3.3% of cases. Conclusion: The Functional Investigation Centre makes it possible to detect anomalies at the end of pregnancy with a view to better planning of delivery.

关键词： Follow-Up End of Pregnancy Scheduled Caesarean Section Prognosis

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Factors Determining the Postponement of Schedule Gyneaco-Obstetric Surgery at CHUMEFJE in Libreville (Gabon)

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Open Journal of Obstetrics and Gynecology 2023年第10期13卷 1699-1710页

作者： Pamphile Assoumou Obiang Jacques Albert Bang Ntamack Ophélia Makoyo ulysse minkobame Jean Pierre Malanda Anouchka Mewie Juvette Elsy Ntsame Robert Eya’ama Ernest Junior Minto’o Jean François Meye Department of Obstetrics and Gynaecology Faculty of Medicine Libreville University of Health Sciences (USS) Libreville Gabon

The study aimed to identify factors causing delays in scheduled gynaeco-obstetric surgeries at CHUMEFJE in Libreville from January 2019 to July 2020. Through a 16-month observational survey, it was found that out of 346 scheduled procedures, 128 (36.4%) were postponed. Organizational issues in the operating theatre were responsible for 80.3% of these delays, with 95.3% being preventable. To enhance efficiency, improvements in operating theatre organization are recommended.

关键词： Scheduled Gynaeco Obstetric Surgery Postponement Determining Factors

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Genetic algorithm-based multiple moving target reaching using a fleet of sailboats

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IET Cyber-Systems and Robotics 2019年第3期1卷 93-100页

作者： Viel Christophe Vaultier ulysse Wan Jian Jaulin Luc School of Engineering Computing and MathematicsUniversity of PlymouthPlymouthDevonUK Lab STICC ENSTA BretagneBrestFrance

This study addresses the problem of Dynamic Travelling Salesman Problem for a multi-agent system using a fleet of sailboats.A genetic algorithm(GA)is proposed,which attributes to each agent a varying number of targets to be *** allows obtaining a suboptimal solution in the shortest time ***,this study adapts it to the specific problem involving a fleet of sailboats,which is a challenging task with comparison to autonomous underwater vehicles or motorised vehicles in terms of the *** motors can be flexibly controlled while sailboat movements are constrained by available wind direction and *** the method takes into account wind conditions at various locations of the *** results demonstrate the effectiveness of the proposed approach.

关键词： agent flex algorithm

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Analysis of Road Embankment Slope Stability

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Open Journal of Civil Engineering 2018年第2期8卷 121-128页

作者： Chunyuan Liu ulysse Sè ho F. Hounsa Hebei University of Technology Tianjin China

The stability of earthworks (cuttings, embankments, dikes) and natural slopes is a?problem that is of concern to geotechnicians, both practitioners and researchers. The disorders generated by breaking the slopes are usually spectacular, often destructive and sometimes murderers. Many methods of calculating stability have been proposed. These are differentiated?by the assumptions accepted by their authors (methods of calculation in equilibrium limit, methods of calculation at break, deformation calculation methods) and the ease of their implementation (calculations using charts, automatic calculations using software), but they all agree to define an overall factor of safety according to which the stability?of?the studied slope is considered to be insured or compromised, or by safety factor spartial effects on the one hand, applied stresses and, on the other hand, the mechanical properties soil. Various embankment strengthening techniques have been developed. They are differentiated by the process of their realization, their cost and their durability. The main objective of this study is to present the problems of both natural and artificial slope stability on construction projects. In this regard, special emphasis?is given to the sensitivity of the calculation model input parameters (soil, load),?which should contribute to raising awareness about this issue, as a prerequisite to make the right decisions and optimal technical solutions in this area.

关键词： Slope Stability Soil Parameters Factor of Safety Simplified Bishop Method

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曲黄高速公路路基承载力与路堤边坡稳定性

曲黄高速公路路基承载力与路堤边坡稳定性

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作者： ulysse Sèho F. Hounsa 河北工业大学

学位级别：硕士

任何一个国家的社会、经济、工业和文化发展都很大程度上取决于其运输系统。能最大限度地为所有人服务的现代办法之一是公路运输。近几年来,由于公路、铁路等基础设施的发展,工程建设用地质量不足。公路路基施工中,路堤必须是稳定和执... 详细信息

任何一个国家的社会、经济、工业和文化发展都很大程度上取决于其运输系统。能最大限度地为所有人服务的现代办法之一是公路运输。近几年来,由于公路、铁路等基础设施的发展,工程建设用地质量不足。公路路基施工中,路堤必须是稳定和执行整个路面的设计寿命。路基往往是路面结构中最薄弱的构件,是影响路面使用性能的重要因素。施工中的路基必须足够稳定,以防止车辙、推挤和推挤。路基还必须提供一个良好的平台,使各种路面层可以有效和有效地放置和压实。此外,高质量的路堤施工也是保持平稳的人行道和提供斜坡稳定性所需要的一个关键因素。优质路堤需要适当的土壤选择、适当的湿度控制和均匀的压实。路堤施工不良引起的问题,有时会导致边坡稳定性问题、侵犯私人财产和破坏排水结构,此外,路面不平整可能是由于不均匀支撑造成的。土工施工是工程中最复杂的工序之一,人们也普遍认识到某些土壤比其他土壤更适合于某些建筑活动,全面认识土壤及其性质是建设优质路堤的必要条件。为了建造优质路堤,必须了解所使用的土壤的具体性质,以便作出适当的现场判断。基于上述问题,本文对路基承载力和路堤边坡稳定性进行了研究:1、首先对公路路面设计的主要因素即经验方法进行了总结,并介绍了相关的工程。2、其次本文介绍了曲黄公路工程位于中国河北省境内,选取该公路路基的两个不同断面,对所测的路基断面数据进行处理和分析,判断路基承载力是否满足相关的要求。3、然后利用数值模拟软件ABAQUS对有限元法进行了数值模拟分析。最后、对数值模拟结果进行了分析。4、研究表明,路堤沉降和边坡稳定性对路基特性、路堤几何构型和建设条件等具有重要的影响。

关键词：公路路基承载力路堤边坡的稳定性数值模拟

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