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急性重症肝炎患者肝性脑病进展的预测

世界核心医学期刊文摘（胃肠病学分册） 2006年第9期2卷 13-13页

作者： Takikawa Y. Endo R. suzuki K. 王顺涛 First Department of Internal Medicine and Open Research Center Advanced Medical Science CenterIwate Medical University19-1 UchimaruMorioka 020-8505Japan Dr.

To identify factors predicting the development of hepatic encephalopathy,164 patients with severe acute hepatitis(SAH),defined as acute hepatitis having a prolonged prothrombin time(PT)of < 40%activity but without hepatic encephalopathy,were prospectively observed at 57 major liver centers in *** the data of 65 patients enrolled from 1997 to 1998,a prediction equation was developed by multiple logistic regression analysis and prospectively evaluated using the data of 99 patients since *** the 164 patients with SAH,51(31 %)developed hepatic *** the etiologic viewpoint,the percentages of patients developing encephalopa-thy were highest in non-A-E hepatitis(41.9%).A predictive model,logit(p)= 0.084 x age(year)+0.129 x serum total bilirubin(TB,in mg/dL)-0.158 x prothrombin time(%)-2.434,was *** conclusion,old age,prolonged PT,elevation of TB,and non-A-E hepatitis are potential risk factors for developing encepha-lopathy in SAH.

关键词：重症肝炎患者急性重症肝炎预测方程式肝性脑病非甲非戊型肝炎凝血酶原时间血清总胆红素总胆红素升高

High Preoperative Anxiety Level and the Risk of Intraoperative Hypothermia

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International Journal of Clinical Medicine（临床医学国际期刊） 2012年第6期

作者： Noriyoshi Tanaka Yuko Ohno Megumi Hori Mai Utada Kenji Ito Toshiyasu suzuki

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放射状视神经切开术中大量出血性视网膜脱离

世界核心医学期刊文摘（眼科学分册） 2006年第8期2卷 45-45页

作者： Takaya K. suzuki Y. Nakazawa M. 王静波 Department of Ophthalmology Hirosaki University School of Medicine 5 Zaifu-cho Hirosaki 036- 8562 Japan

Background: We encountered obvious arterial bleeding from the incision site during radial optic neurotomy (RON) in a 55- year-old woman with central retinal vein occlusion (CRVO) and report the findings herein. Case report: The patient initially demonstrated a retinal hemorrhage and macular edema due to a left CRVO. Her corrected visual acuity was 0.5 OS. Since her symptoms did not improve and were aggravated, even though she received an oral anticoagulant drug orally, RON was performed 2 months after the onset of symptoms. During surgery, obvious arterial bleeding started from the RON incision site and it was not arrested although the infusion bottle was fully elevated. However, a subsequent infusion of liquid perfluorocarbon successfully stopped the bleeding by direct pressure. Hemorrhagic retinal detachment occurred in the nasal quadrant and postoperative vitreous hemorrhage was treated surgically. The hemorrhagic retinal detachment was gradually absorbed and replaced by fibrous scar tissue. Two years after the surgery, no expansion of retinal detachment has been observed and correctedvisual acuity is being maintained at 0.2 OS. Conclusion: We conclude that RON for CRVO carries a risk of arterial bleeding and that infusion of liquid perfluoro-carbon seems to be effective to arrest arterial bleeding from the RON site.

关键词：视网膜脱离灌注瓶视网膜出血玻璃体积血动脉出血切口位置黄斑水肿矫正视力全氟化碳直接压

单用干扰素治疗血清转氨酶水平正常的慢性丙型肝炎患者

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世界核心医学期刊文摘（胃肠病学分册） 2005年第3期1卷 53-53页

作者： Mamori S. suzuki F. Hosaka T. 姜建涛 Department of Gastroenterology Toranomon Hospital 2-2-2 Toranomon Minato-ku Tokyo 105-8470 Japan

Background. Approximately 30%of patients with chronic hepatitis C have normal serumalanine amino transferase (ALT) levels. While interferon (IFN) mono therapy is approved for patients with chronic hepatitis C infection, the effectiveness of such therapy for chronic hepatitis C patients with normal ALT levels at commencement of treatment remains poorly understood. Methods. Ninety four individuals (M/F, 54∶40; median age, 46 years) with normal ALT levels (< 50 IU/ 1) at the commencement of treatment who were positive for both antihepatitis C virus (HCV) and serum HCV RNA were studied. Among this group, 18 individuals (M/F, 9∶9; median age, 50 years) had had persistently normal ALT levels for at least 3 months prior to treatment. All patients received their first course of IFN therapy in this study. Results. Forty three (45.7 %) of 94 individuals had lost serum HCV RNA at 6 months after cessation of therapy (complete response; CR). The proportion of patients with genotype 2a and HCV RNA level over 1 Meq/ml who showed CR was significantly lower in those with normal ALT levels than in those with elevated ALT levels (23.8%vs 55.6%; P = 0.0189). Two patients who had persistently normal ALT levels and HCV RNA level over 1 Meq/ml were non responders (NR) and had ALT flare ups after IFN therapy. Patients with HCV RNA levels of less than 1 Meq/ml did not show differential responses based on ALT levels. Conclusions. Our data suggest that IFN therapy is effective for patients with normal ALT levels and less than 1 Meq/ml HCV RNA. Thus, such patients should be considered for curative IFN therapy.

关键词：慢性丙型肝炎干扰素治疗血清转氨酶证实有效 RNA

Influence of the period between onset of IgA nephropathy and medical intervention on renal prognosis

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Effects of cola intake on fertility: a review

Health（健康） 2011年第8期

作者： Keiko Okazaki Yusuke suzuki Takashi Kobayashi Fumiko Kodama Satoshi Horikoshi Yasuhiko Tomino

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日本慢性HBV感染者应用干扰素治疗6个月的疗效

Health（健康） 2010年第9期

作者： Atsushi Imai Satoshi Ichigo Hiroshi Takagi Kazutoshi Matsunami Noriko suzuki Akio Yamamoto

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世界核心医学期刊文摘（胃肠病学分册） 2005年第5期1卷 46-46页

作者： suzuki F. Arase Y. Akuta N. 赵天智 Department of Gastroenterology Toranomon Hospital 2-2-2 Toranomon Minato-ku Tokyo 105-8470 Japan

Background: In Japan, there are few studies of long-term (more than 1 month) interferon (IFN) therapy for chronic hepatitis B (CHB). In this retrospective study, we investigated the efficacy and predictors of response to 6-month IFN therapy. Methods: We analyzed 66 Japanese patie nts with CHB who were treated with IFN for 6 months. They comprised patients who were hepatitis B e antigen (HBeAg)-positive (n = 45) and -negative (n = 21). One (2%), 8 (12%), and 51 (77%) patients were infected with hepatitis B virus (HBV) genotypes A, B, and C, respectively. Responders in patients positive for HBeAg were defined as those who showed normalization of serum alanine aminotransferase (ALT) level, HBeAg loss, and HBV DNA negativity at 6 months after completion of IFNtherapy. In patients negative for HBeAg, responders were defined as those patients who showed normalization of ALT level and HBV DNA negativity at the same 6-month time point. Results: Of the 45 patients with HBeAg at the commencement of IFN therapy,9 (20%) were responders. Young patients, especially those with a high serum ALT level, were significantly more likely to respond to IFN therapy. Of the 21 patients negative for HBeAg, 13 (62%) were responders. There were no significant differences in clinical characteristics between responders and nonresponders among patients negative for HBeAg. Multivariate analyses identified HBeAg negativity and young age as independent factors associated with a positive response to 6-month IFN therapy. However, long-term follow-up of the treated patients showed a fall in the response rate. Conclusions: The response rate to 6-month IFN therapy among HBeAg-positive patients was low. However, young patients may require long-term IFN therapy.

关键词：干扰素治疗治疗应答应答者阴性患者乙型肝炎应答率多变量分析

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强电子束引发的高功率HF化学激光器的研制

中国激光 1983年第Z1期 592-592页

作者： Fumihiko Kannari Shigeru Yamaguchi Kenji Kumamoto Tadashi suzuki Minoru Obara Tomoo Fujioka 日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系日本庆应大学科学技术分部电工系

强电子束是高功率激光器的一种重要的引发和激励源,由于高的引发和激励强度能均匀地激励高气压、大体积气体混合物。此外,电子束脉冲具有很快的电流上升时间,这样可以研究寿命很短的激光物质。电子束引发的HF化学激光器对应用于激光聚... 详细信息

强电子束是高功率激光器的一种重要的引发和激励源,由于高的引发和激励强度能均匀地激励高气压、大体积气体混合物。此外,电子束脉冲具有很快的电流上升时间,这样可以研究寿命很短的激光物质。电子束引发的HF化学激光器对应用于激光聚变来说是有兴趣的,引起这种兴趣的特性是由于HF化学激光器可以获得高的电效率和高的能量密度。我们已对电子束引发的HF（H2/F2）激光器作了研究,并获得了电效率为200％时180J/脉冲的HF激光能量。最近,我们已研制成几千焦耳的电子束引发的高功率HF激光系统。强电子束引

关键词：电效率激光能量化学激光器高功率

CO在Ni-k/Al2O3系催化剂上吸附红外光谱研究

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燃料化学学报 1983年第4期 61-68页

作者：周泽兴水野光一铃木正臣中国科学院环境化学研究所日本国工业技术院公害资源研究所

用红外光谱技术研究了（1）室温至300℃时CO 在Ni-K/Al2O3系催化剂上的吸附态,（2）室温抽气脱附中各吸附态的稳定性及（3）吸附CO 的解离。CO 吸附时形成的表面生成物为:一氧化碳（CO）,羧酸基（COO-）,碳酸氢盐（HCO3-）,简单碳酸盐... 详细信息

用红外光谱技术研究了（1）室温至300℃时CO 在Ni-K/Al2O3系催化剂上的吸附态,（2）室温抽气脱附中各吸附态的稳定性及（3）吸附CO 的解离。CO 吸附时形成的表面生成物为:一氧化碳（CO）,羧酸基（COO-）,碳酸氢盐（HCO3-）,简单碳酸盐和二配位碳酸盐（CO3-）。各种吸附态的稳定性与催化剂中K 含量及温度的关系密切。在K 含量>1mg atom/g-Al2O3的催化剂上,在1803—1774cm-1形成了一个稳定的、构型尚不清楚的CO 吸附态。另外,讨论了表面羧酸基和碳酸盐形成的机理。

关键词：催化剂吸附态吸收带红外光谱 IR 光谱 Ni-k/Al2O3 CO Al