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汽车齿轮 1992年第2期 11-20页

作者： tsay,cb 吴希让

Clinical and socioeconomic determinants of survival in biliary tract adenocarcinomas

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1374-1383页

作者： Laura Sahyoun Kay Chen Cynthia tsay George Chen Petr Protiva Department of Gastroenterology and Hepatology Weill Cornell MedicineNew YorkNY 10065United States Gastroenterology Section Jennifer Moreno VA San Diego Healthcare SystemSan DiegoCA 92161United States Division of Gastroenterology Department of MedicineUniversity of California San DiegoLa JollaCA 92093United States Department of Gastroenterology and Hepatology John Hopkins HospitalBaltimoreMD 21287United States Department of Digestive Diseases Yale New Haven HospitalNew HavenCT 06520United States Department of Gastroenterology VA Connecticut Health Care SystemWest HavenCT 06516United States

BACKGROUND Despite advances in detection and treatments,biliary tract cancers continue to have poor survival ***,there is limited data investigating the significance of socioeconomic status,race/ethnicity,and environmental factors in biliary tract cancer *** from the Surveillance,Epidemiology,and End Results database for biliary and gallbladder adenocarcinomas were extracted from 1975 to ***-conomic data included smoking,poverty level,education,adjusted household income,and percentage of foreign-born persons and urban *** was calculated with Cox proportional hazards models for death in the 5-year period following *** Our study included 15883 gallbladder,11466 intrahepatic biliary,12869 extrahepatic biliary and 7268 ampulla of Vater adenocarcinoma *** analyzing county-specific demographics,patients from counties with higher incomes were associated with higher survival rates[hazard ratio(HR)=0.97,P<0.05].Similarly,counties with a higher percentage of patients with a college level education and counties with a higher urban population had higher 5-year survival rates(HR=0.96,P=0.002 and HR=0.97,P=0.004,respectively).CONCLUSION Worse survival outcomes were observed in lower income counties while higher income and education level were associated with higher 5-year overall survival among gallbladder and biliary malignancies.

关键词： Biliary tract cancers Survival Outcomes research Socioeconomic factors Healthcare disparities

Assessing the Effectiveness of Strategies in US Birth Cohort Screening for Hepatitis C Infection

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Journal of Clinical and Translational Hepatology 2020年第1期8卷 25-41页

作者： Cynthia J.tsay Joseph K.Lim Department of Internal Medicine Yale University School of MedicineNew HavenCTUSA Yale Liver Center Section of Digestive DiseasesYale University School of MedicineNew HavenCTUSA

Chronic hepatitis C infection in the USA is a highly morbid condition and current guidelines recommend one-time screening among the birth cohort(1945-1965).Understand-ing strategies to optimize screening can help inform future hepatitis C virus(HCV)screening guidelines.A focused literature search was performed using PubMed and manual abstract review from major hepatology conferences over the past 2 *** search strategy involved using Medical Subject Headings terms for hepatitis C,screening,birth cohort,baby boomers,and *** review was limited to data from the USA.A total of 327 articles were identified and 36 abstracts were included,with studies published between *** including clinician education,electronic medical record alerts,reflex HCV RNA testing,point-of-care testing,multisite(outpatient,inpatient,emergency department,endoscopy suite)initiatives,direct patient solicitation,and utilization of non-physician providers have increased HCV screening ***,broad imple-mentation remains less than *** include lack of patient acceptance to screening and engagement in the HCV care *** Veterans Affairs Healthcare System has achieved higher birth cohort screening rates through an integrated approach requiring high-level engagement by leadership and institutional *** strategies for increasing birth cohort screening have been successful,but overall rates of HCV screening remain *** strat-egies can inform public health efforts to implement emerging national recommendations for expansion of HCV screening to all *** age 18 or older.

关键词： Hepatitis C Epidemiology HCV antibody Screening Birth cohort Baby boomers Care cascade Electronic medical records

Carbon storage potential of avenue trees:a comparison of Barringtonia racemosa,Cyclobalanopsis glauca,and Alnus formosana

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Journal of Forestry Research 2015年第2期26卷 307-314页

作者： Jyh-Shyan tsay Pei-Hsin Ko Pai-Tsang Chang Department of Horticultural Science National Chiayi University

Trees in cities play a valuable public health role for they are able to use photosynthesis to absorb atmospheric carbon dioxide(CO2),which is then stored as tree *** present study compared the potential for carbon storage in the aboveground tree biomass of 3-year-old specimens of Barringtonia racemosa,Cyclobalanopsis glauca,and Alnus formosana grown in Chiayi City,*** of the carbon storage of avenue trees was based on measurement of the photosynthetic rate and leaf area,as well as the biomass of timbers,from October 2008 to *** on photosynthetic rates and leaf area,the estimated carbon stocks of ***,***,and *** are 756,615,and2738 kg Cha-1a-1,*** addition,carbon storage can be estimated based on timber volume,and these results are 1170,720,and 1995 kg Cha-1a-1for ***,***,and ***,*** on these findings,*** has the highest carbon fixation potential of these three *** the photosynthetic rate measurements can provide detailed data on the diurnal changes in carbon stocks,this requires more time and *** contrast,timber volume measurements provide a rapid and convenient way to estimate carbon stocks.

关键词： Carbon dioxide Carbon stock Greenhouse gas Leaf area Timber volume

SYNTHESIS　OF　TETRAMETHYL　SALVIANOLIC　ACID　F　AND　TRIMETHYL　PRZEWALSKINIC　ACID　A

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Chinese Chemical Letters 1996年第5期7卷 427-430页

作者： Al, cb Li, LN CHINESE ACAD MED SCI INST MAT MEDBEIJING 100050PEOPLES R CHINA

Abstract: Salvianolic acid F (1a) and przewalskinic add A(2a) are phenolic acids isolated from the traditional and herbal Chinese medicines Salvia miltiorrhiza (1) and S. przewalskii (2). The chemical structures of these two compounds represent the main carbon skeletons of the biologically active depsides salvianolicacid A and B isolated from S. miltionhiza (3.4). The present paper reports the synthesis of the methyl ether protected phenolic acids. tetramethyl salvianolic acid F(1b) and trimethyl prsewalskinic acid A(2b).

关键词： ACID TRIMETHYL TETRAMETHYL PRZEWALSKINIC SALVIANOLIC SYNTHESIS AND OF

Investigation on the computation of atomic multipole moments with the modified cumulative potential-derived semiempiricalmethod

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Chinese Journal of Chemistry 1997年第6期15卷 481-491页

作者： Xu, LJ Zhu, cb Yan, JM Chinese Acad Sci Inst Chem Beijing 100080 Peoples R China

The suitability of calculating atomic multipole moments from AM1 wave functions by cumulative potential-derived method has been investigated. It is shown that this method has a faster convergence of the fitting process and gives a better description of the charge distribution than the original PD method. Atomic charges obtained in this way are of comparable quality with 6-31G* data and the calculated dipole moments are closer to the experimental data than the values computed directly from the AM1 charges. The results demonstrate that the atomic multipole moments higher than monopole moment can be used to supplement the atomic charge to obtain a more accurate description of charge distribution. For the sake of comparison, both the Williams fitting potential surface and the Connolly one are used in the calculation.

关键词： atomic charge atomic multipole moment cumulative fitting AM1

INVESTIGATION　ON　THE　INTERACTION　OF　THE　HALOGEN　ATOMS　WITH　THE　C_（60）　CAGE　IN　THE　HALOGEN－ENCLOSED　COMPLEXES　（HALOGEN＠C_（60））

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Chinese Chemical Letters 1995年第10期6卷 867-870页

作者： Zhu, cb Yan, JM Acad Sinica Inst Chem Beijing 100080 Peoples R China

The interaction between C60 cage and the centerhalogen atoms in endoheoral complexes(HalogenC60)(Halogen=Hal=F,ClBr1),including electro-static interaction,dispersive interection and repulsive interaction,have been calculated by molecular molecular mechanics method combined with the results obtained by quantum-chemical EHMO/ASED method The computational results show that the total interaction is attraction which reduces the endohedral comples system except for,and the electro-static interaction plays a decisive role in the three forms of interactions,reaching up more than 90%. For the endohedral complex the resultant non-bonded interaction is *** is a similar variation trend for the total energy variation of system and the total interaction energy of which the order is (F@C_(60))<(cl@C(60))<(I@C(60)).

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Annealing Effect on Mechanical Properties of Ti_(51)Ni_(13)Pd_(36)High Temperature Memory Alloy

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Journal of Materials Science & Technology 2000年第5期16卷 531-533页

作者： Xu, HB Hu, SQ Jiang, cb Gong, SK Beijing Univ Aeronaut & Astronaut Dept Mat Sci & Engn Beijing 100083 Peoples R China

The high temperature shape memory alloy Ti51Ni13Pd36 was subjected to a cold working and annealing treatment to improve its mechanical properties and the shape memory effect. It was found that recovery of the cold worked alloys started at near 673 K and the recrystallization temperature was at about 748 K. The grain size decreased with the increase of annealing temperature below 923 K and then increased when above 923 K. The smallest average grain size of about 3.5μm, which is approximately 10 times smaller than the hot rolled one, permitted the best combination of the mechanical properties in the alloy annealed at 923 K for 1h. The cold rolling raised the peak temperature of reverse transformation. This temperature dropped very sharply when the specimen was annealed at temperatures higher than 673 K.

关键词： Alloys

A new look at anti-Helicobacter pylori therapy

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World Journal of Gastroenterology 2011年第35期17卷 3971-3975页

作者： Seng-Kee Chuah Feng-Woei tsay Ping-I Hsu Deng-Chyang Wu Division of Gastroenterology Kaohsiung Chang Gung Memorial HospitalCollege of MedicineChang Gung University833 KaohsiungTaiwan Division of Gastroenterology Department of Internal MedicineKaohsiung Veterans General HospitalNational Yang-Ming University813 KaohsiungTaiwan Department of General Medicine School of MedicineCollege of MedicineTaipei Medical University110 TaipeiTaiwan Department of Internal Medicine Kaohsiung Medical University Hospital807 KaohsiungTaiwan

With the rising prevalence of antimicrobial resistance,the treatment success of standard triple therapy has recently declined to unacceptable levels (i.e.,80% or less) in most ***,several treatment regimens have emerged to cure Helicobacter pylori (***) *** first-line *** therapies in 2011 include sequential therapy,concomitant quadruple therapy,hybrid (dual-concomitant) therapy and bismuth-containing quadruple *** the failure of standard triple therapy,a bismuth-containing quadruple therapy comprising a proton pump inhibitor (PPI),bismuth,tetracycline and metronidazole can be employed as rescue ***,triple therapy combining a PPI,levofloxacin and amoxicillin has been proposed as an alternative to the standard rescue *** salvage regimen can achieve a higher eradication rate than bismuth-containing quadruple therapy in some regions and has less adverse *** best second-line therapy for patients who fail to eradicate *** with first-line therapies containing clarithromycin,amoxicillin and metronidazole is ***,a levofloxacin-based triple therapy is an accepted rescue *** guidelines suggest that patients requiring third-line therapy should be referred to a medical center and treated according to the antibiotic susceptibility ***,an empirical therapy (such as levofloxacin-based or furazolidone-based therapies) can be employed to terminate *** infection if antimicrobial sensitivity data are unavailable.

关键词： Bismuth-containing quadruple therapy Concomitant quadruple therapy Hybrid (dual-concomitant) therapy Rescue anti-Helicobacter pylori treatment Sequential therapy

Y-Ba-Cu-O mixed oxides for production of diphenols in liquid-solid phase

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Chinese Journal of Chemistry 1996年第6期14卷 516-524页

作者： Liu, cb Zhao, Z Yang, XG Ye, XK Wu, Y CHINESE ACAD SCI CHANGCHUN INST APPL CHEMCHANGCHUN 130022JILINPEOPLES R CHINA

Superconductor mixed oxides were often used as catalysts at higher temperature in gas phase oxidations, and considered not suitable for lower temperature reactions in the liquid-solid phase; here the catalysis of YBa2Cu3O7+/-x and Y2BaCuO5+/-x in the phenol hydroxylation at lower temperature with H2O2 as oxygen donor was studied, and found that the superconductor YBa2Cu3O7+/-x, has no catalytic activity for phenol hydroxylation, but Y2BaCuO5+/-x does, even has better catalytic activity and stability than most previously reported ones. With the studies of catalysis of other simple metal oxides and perovskite-like mixed oxides, a radical substitution mechanism is proposed and the experimental facts are explained clearly, and draw a conclusion that the perovskite-like mixed oxides with (AO)(ABO(3)) and (AO)2(ABO(3)) structure have better catalytic activity than the simple perovskite oxides with (ABO(3))(3) structure alone, and (AO) structure unit is the key for the mixed oxides to have the phenol hydroxylation activity. No pollution of this process is very important for its further industrial application.

关键词： superconductor mixed oxides phenol hydroxylation radical substitution