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Journal of Sport and Health Science 2024年第5期13卷 666-669页

作者： Terese L.Chmielewski Adam Meierbachtol Rick Aberman travis Gunderson Jonathon Sikorski Kathleen Cummer TRIA Orthopedic Center BloomingtonMN 55431USA Rehabilitation Science Graduate Program Department of Family Medicine and Community HealthMedical SchoolUniversity of MinnesotaMinneapolisMN 55455USA Optum Inc. Clinical OperationsPhysical Health DivisionEden PrairieMN 55344USA Dr.Rick Aberman Consulting MinnetonkaMN 55305USA Department of Rehabilitation Medicine Division of Physical TherapyUniversity of WashingtonSeattleWA 98195USA

Helping athletes return to sports participation is a primary goal of anterior cruciate ligament(ACL)reconstruction *** facilitate the achievement of this goal,decades of research studies have sought to identify knee impairments that reduce knee function as well as interventions to resolve them.1Yet,over the past 10 years,research pertaining to psychological responses(i.e.,cognitions and emotions)after ACL reconstruction has grown exponentially—a phenomenon that can be visualized by entering the search terms"psychological"and"anterior cruciate ligament reconstruction"into the PubMed search engine.

关键词： ligament return psychological

Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins

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Assessment of Lung Cancer Risk on the Basis of a Biomarker P...

Oncologic outcomes with and without amniotic membranes in robotic-assisted radical prostatectomy:A propensity score matched analysis

2019年中国肿瘤标志物学术大会暨第十三届肿瘤标志物青年科学家论坛

作者： sun,nan Florence,Guida Bantis,LeonidasE. Muller,DavidC. Li,Peng Taguchi,Ayumu Dhillon,Dilsher Kundnani,DeepaliL. Patel,NikulJ. Yan,Qingxiang Byrnes,Graham Moons,KarelG.M. Tj?nneland,Anne Panico,Salvatore Claudia ,Agnoli Vineis,Paolo Palli,Domenico Bueno-de-Mesquita,Bas Peeters,PetraH. Agudo,Antonio Huerta,JoseM. Dorronsoro,Miren Barranco,MiguelRodriguez Ardanaz,Eva travis,ruthc. Byrne,KarlSmith Boeing,Heiner Steffen,Annika Kaaks,Rudolf Hüsing,Anika Trichopoulou,Antonia Lagiou,Pagona LaVecchia,Carlo Severi,Gianluca Boutron-Ruault,Marie-Christine Sandanger,TorkjelM. Weiderpass,Elisabete N?st,ThereseH. Tsilidis,Kostas Riboli,Elio Grankvist,Kjell Johansson,Mikael Goodman,GaryE. Feng,Ziding Brennan,Paul Johansson,Mattias Hanash,Samir M. The University of Texas MD Anderson Cancer Center Genetic Epidemiology Group International Agency for Research on Cancer Department of Biostatistics The University of Texas MD Anderson Cancer Center Department of Epidemiology and Biostatistics Imperial College London School of Public Health Laboratory of Population Health Max Planck Institute for Demographic Research Department of Translational Molecular Pathology The University of Texas MD Anderson Cancer Center Environment and Radiation Section International Agency for Research on Cancer Department of Epidemiology Julius Center for Health Sciences and Primary CareUniversity Medical Center Unit of Diet Genesand EnvironmentDanish Cancer Society Research Center Department of Clinical Medicine and Surgery Federico Ⅱ University Epidemiology and Prevention Unit Fondazione IRCCS Istituto Nazionale dei Tumori Molecular and Genetic Epidemiology Unit Human Genetics Foundation Cancer Risk Factors and Life-Style Epidemiology Unit Cancer Research and Prevention Institute-Istituto per lo Studio ela Prevenzione Oncologica Department for Determinants of Chronic Diseases National Institute for Public Health and the Environment Unit of Nutirition and Cancer Cancer Epidemiology Research ProgramCatalan Institute of OncologyBellvitge Institute for Biomedical Research (IDIBELL)L’Hospitalet de Llobregat Department of Epidemiology Murcia Regional Health Council Biomedical Research Institute of Murcia(IMIB-Arrixaca) Centro de Investigación Biomédica en Red Epidemiología y Salud Pública (CIBERESP) Public Health Direction and Biodonostia Research Institute-CIBERESP Escuela Andaluza de Salud Pública Instituto de Investigación Biosanitaria Hospitales Universitarios de Granada/Universidad de Granada Epidemiology Preventionand Promotion Health ServiceNavarra Public Health Institute Instituto de Investigación Sanitaria de Navarra (IdiSNA) Navarra Institute for Health Research Cancer Epidemiology Unit Nuffield Department of Population HealthUniversity of Oxford Department of Epidemi

IMPORTANCE:There is an urgent need to improve lung cancer risk assessment because current screening criteria miss a large proportion of ***:To investigate whether a lung cancer risk prediction model based on a panel of selected circulating protein biomarkers can outperform a traditional risk prediction model and current US screening criteria.

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Asian Journal of Urology 2024年第1期11卷 19-25页

作者： Jonathan Noël Daniel Stirt Marcio Covas Moschovas Sunil Reddy Abdel Rahman Jaber Marco Sandri Seetharam Bhat travis Rogers Subuhee Ahmed Anya Mascarenhas Ela Patel Vipul Patel Advent Health Global Robotics Institute CelebrationFLUSA University of Central Florida College of Medicine OrlandoFLUSA Big and Open Data Innovation Laboratory University of BresciaItaly SUNY Upstate Medical University SyracuseNYUSA Kansas City University College of Medicine Kansas CityMOUSA Harvard University CambridgeMAUSA

Objective:Placement of human placenta derived grafts during robotic-assisted radical prostatectomy(RARP)hastens the return of continence and *** long-term impact on the oncologic outcomes remains to be *** objective was to determine the oncologic outcomes of patients with dehydrated human amnion chorion membrane(dHACM)at RARP compared to a matched ***:In a referral centre,from August 2013 to October 2019,599 patients used dHACM in bilateral nerve-sparing *** excluded patients with less than 12 months follow-up,simple prostatectomy,and unilateral *** with dHACM(amnio group)were 529,and were propensity score matched 1:1 to 2465 patients without dHACM(non-amnio group)and a minimum follow-up of 36 *** the time of RARP,dHACM was placed around the neurovascular bundle in the amnio *** and categorical variables in matched groups was tested by two-sample Kolmogorov-Smirnov test and Fisher's exact test *** measured were biochemical recurrence(BCR),adjuvant and salvage therapy ***:Propensity score matching resulted in two groups of 444 *** incidence functions for BCR did not show a difference between the groups(p=0.3).Patients in the non-amnio group required salvage therapy more frequently than the amnio group,particularly after partial nerve-sparing RARP(6.3%vs.2.3%,p=0.001).Limitations are the absence of prospective ***:The data suggest that using dHACM does not have a negative impact on BCR in *** of cancer specific and overall survival will require follow-up study to increase our understanding of these grafts’impact on prostate cancer biology.

关键词： Prostatectomy Prostatecancer Robotic Oncology Outcome Allograft Biomaterial Dehydrated human amnionchorion membrane

Mixed-Vehicular Aggregated Transportation Network Design Considering En-route Recharge Service Provision for Electric Vehicles

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Journal of Systems Science & Complexity 2018年第5期31卷 1329-1349页

作者： ZHANG Xiang WALLER S travis School of Civil and Environmental Engineering University of New South Wales Australia

This paper addresses the transportation network design problem （NDP） wherein the dis- tance limit and en-route recharge of electric vehicles are taken into account. Specifically, in this work, the network design problem aims to select the optimal planning policy from a set of infrastructure design scenarios considering both road expansions and charging station allocations under a specified construction budget. The user-equilibrium mixed-vehicular traffic assignment problem with en-route recharge （MVTAP-ER） is formulated into a novel convex optimization model and extended to a newly developed bi-level program of the aggregated NDP integrating recharge facility allocation （NDP-RFA）. In the algorithmic framework, a convex optimization technique and a tailored CA are adopted for, respectively, solving the subproblem MVTAP-ER and the primal problem NDP-RFA. Systematic ex- periments are conducted to test the efficacy of the proposed approaches. The results highlight the impacts of distance limits and budget levels on the project selection and evaluation, and the benefits of considering both road improvement policy and recharge service provision as compared to accounting for the latter only. The results also report that the two design objectives, to respectively minimize the total system travel time and vehicle miles travelled, are conflicting for certain scenarios.

关键词： Aggregated network design problem mixed-vehicular traffic assignment recharge facilityallocation transport system optimization.

Tudor and its domains: germ cell formation from a Tudor perspective

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Cell Research 2005年第4期15卷 281-291页

作者： travis THOMSON,Paul LASKO Department of Biology McGill University Montreal Quebec Canada H3A 1B1 Department of Biology McGill University Montreal Quebec Canada H3A 1B1

In many metazoan species, germ cell formation requires the germ plasm, a specialized cytoplasm which often con-tains electron dense structures. Genes required for germ cell formation in Drosophila have been isolated predominantlyin screens for maternal-effect mutations. One such gene is tudor (tud); without proper tud function germ cell formationdoes not occur. Unlike other genes involved in Drosophila germ cell specification tud is dispensable for other somaticfunctions such as abdominal patterning. It is not known how TUD contributes at a molecular level to germ cell forma-tion but in tud mutants, polar granule formation is severely compromised, and mitochondrially encoded ribosomal RNAsdo not localize to the polar granule. TUD is composed of 11 repeats of the protein motif called the Tudor domain. Thereare similar proteins to TUD in the germ line of other metazoan species including mice. Probable vertebrate orthologuesof Drosophila genes involved in germ cell specification will be discussed.

关键词： Drosophila tudor germ cells germ plasm Tudor domains.

Creation and Evaluation of a Multi-sensory Virtual Assembly Environment

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International Journal of Automation and computing 2008年第2期5卷 163-173页

作者： Adrian R L travis Department of Engineering University of Cambridge

The multi-modal information presentation, integrated into the virtual environment （VE）, has potential for stimulating different senses, improving the user＇s impression of immersion, and increasing the amount of information that is accepted and processed by the user＇s perception system. The increase of the useful feedback information may reduce the user＇s cognitive load, thus enhancing the user＇s efficiency and performance while interacting with VEs. This paper presents our creation of a multi-sensory virtual assembly environment （VAE） and the evaluation of the effects of multi-sensory feedback on the usability. The VAE brings together complex technologies such as constraint-based assembly simulation, optical motion tracking technology, and real-time 3D sound generation technology around a virtual reality workbench and a common software platform. The usability evaluation is in terms of its three attributes： efficiency of use, user satisfaction, and reliability. These are addressed by using task completion times （TCTs）, questionnaires, and human performance error rates （HPERs）, respectively. Two assembly tasks have been used to perform the experiments, using sixteen participants. The outcomes showed that the multi-sensory feedback could improve the usability. They also indicated that the integrated feedback offered better usability than either feedback used in isolation. Most participants preferred the integrated feedback to either feedback （visual or auditory） or no feedback. The participants＇ comments demonstrated that nonrealistic or inappropriate feedback had negative effects on the usability, and easily made them feel frustrated. The possible reasons behind the outcomes are also analysed by using a unifying human computer interaction framework. The implications, concluded from the outcomes of this work, can serve as useful guidelines for improving VE system design and implementation.

关键词： Usability virtual environment (VE) assembly simulation multi-sensory feedback task performance

Online optimal control of nonlinear discrete-time systems using approximate dynamic programming

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控制理论与应用（英文版） 2011年第3期9卷 361-369页

作者： travis DIERKS Sarangapani JAGANNATHAN DRS Sustainment Systems Inc.201 Evans Lane Department of Electrical and Computer Engineering Missouri University of Science and Technology

In this paper,the optimal control of a class of general affine nonlinear discrete-time(DT) systems is undertaken by solving the Hamilton Jacobi-Bellman(HJB) equation online and forward in *** proposed approach,referred normally as adaptive or approximate dynamic programming(ADP),uses online approximators(OLAs) to solve the infinite horizon optimal regulation and tracking control problems for affine nonlinear DT systems in the presence of unknown internal *** the regulation and tracking controllers are designed using OLAs to obtain the optimal feedback control signal and its associated cost ***,the tracking controller design entails a feedforward portion that is derived and approximated using an additional OLA for steady state *** update laws for tuning the unknown parameters of the OLAs online are *** techniques are used to show that all signals are uniformly ultimately bounded and that the approximated control signals approach the optimal control inputs with small bounded *** the absence of OLA reconstruction errors,an optimal control is *** results verify that all OLA parameter estimates remain bounded,and the proposed OLA-based optimal control scheme tunes itself to reduce the cost HJB equation.

关键词： Online nonlinear optimal control Hamilton Jacobi-Bellman Online approximators Discrete-time systems

Domestication-related changes in seed dispersal and pigmentation:Visual selection and functional trait?

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Molecular Plant 2023年第8期16卷 1240-1242页

作者： Petr Smykal travis Parker Department of Botany Palacky University in Olomouc77900 OlomoucCzech Republic Department of Plant Sciences University of CaliforniaDavisDavisCA 95616USA

The development of agriculture is one of the most transformative changes in the history of *** the most common changes occurring during plant domestication are reductions in seed dispersal and changes in *** there are archaeological records of these processes,the advancement of genomics offers a tool to achieve greater insight into the process of converting wild plants into crops(Smýkal et al.,2018).This involved and resulted in a set of specific phenotypic changes referred to collectively as the domestication ***,less obvious domestication-related modifications have also been identified,including changes in plant *** processes are often *** example,among visible changes,selection for visual appearance such as pigmentation is governed by modulation of specific metabolic *** genomic tools,the improvement of analytical methods provides the opportunity to reveal metabolomic changes involved in plant domestication.

关键词： Visual collective crops

Flammability risk assessment for oil spill response operations

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Acta Oceanologica Sinica 2019年第9期38卷 113-119页

作者： Aurelien Hospital travis Miguez James Stronach Air Coastal and Lake Engineering Department Tetra Tech Canada

Immediately following a spill at sea, released oil ranging from diesel to light crude and diluted bitumen, will initially weather through evaporation, resulting in an elevated concentration of light hydrocarbons in the air. As part of oil spill response operations, first responders use hand-held devices to monitor airborne concent- rations when approaching a spill. The feasibility of using numerical modelling as an additional tool to assess potential flammability and plan response operations in the spill area was explored in this study. The Lower Explosive Limit (LEL) is defined as the minimum concentration of a gas in air, in this case a mixture of evaporated hydrocarbons, which can produce a flash fire in the presence of an ignition source. This ignition source could be triggered by the vessel itself or by spill response operations. A framework was put into place, utilizing a three- dimensional hydrodynamic model (H3D), an oil spill model (SPILLCALC), and an air dispersion model (CALPUFF) to assess the risk of possible ignition of the hydrocarbon vapour in the event of a spill. The study looked at a hypothetical credible worst case tanker spill (16 500 m3) of diluted bitumen (cold lake winter blend) occurring at Arachne Reef in Haro Strait, British Columbia, Canada. SPILLCALC provided one-minute averaged vapour fluxes from the water surface for each of 17 modelled pseudo-components which were used as inputs to CALPUFF. Using the predicted airborne concentrations of each pseudo-component, time-scaled to one-second averages, the flammability potential in the immediate spill area was determined at each grid point using Le Chatelier’s mixing equation. The approach describe here was developed as a proof of concept, and could be established as a real-time system, bringing valuable information in addition to hand-held devices during a spill response, or during a response exercise. This modelling study was conducted as part of Kinder Morgan’s Trans Mountain Pipeline Expan

关键词： oil spill response operations modelling Salish Sea

Advancements and challenges in treating advanced gastric cancer in the West

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World Journal of Gastrointestinal Oncology 2019年第9期11卷 652-664页

作者： Jennifer L Leiting travis E Grotz Division of Hepatobiliary and Pancreas Surgery Mayo Clinic

Gastric cancer is a leading cause of cancer incidence and death *** with advanced gastric cancer benefit from a multi-modality treatment *** oncologic resection with negative margins and complete lymphadenectomy plays a crucial role in long-term survival for patients with resectable *** utilization of minimally invasive techniques for gastric cancer has been slowly increasing and is proving to be both technically and oncologically *** chemotherapy is the current standard of care for advanced gastric cancer.A variety of chemotherapy regimens have been used with the combination of docetaxel,oxaliplatin,5-fluorouracil,and leucovorin being the current recommendation given its superior ability to induce a complete pathologic response and prolong *** use of radiation has been more controversial with its optimal place in the treatment sequence being *** are current ongoing studies assessing the impact of radiation as an adjunct or in place of *** treatments(e.g.,trastuzumab for human epidermal growth factor receptor 2 positive tumors and pembrolizumab for programmed death-ligand 1 positive tumors)are showing promise and are part of a continued emphasis on individualized *** chemotherapy may also play a role in preventing peritoneal recurrences for patients with high risk *** treatment of patients with advanced gastric cancer in the West continues to advance and improve with a better understanding of optimal treatment sequences and the utilization of personalized treatment regimens.

关键词： Gastric cancer D2 lymphadenectomy Minimally invasive surgery Neoadjuvant chemotherapy Chemoradiation Targeted treatments