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The impact of post-operative atrial fibrillation on outcomes in coronary artery bypass graft and combined procedures

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Journal of Geriatric Cardiology 2021年第5期18卷 319-326页

作者： Yau-lam Alex Chau Ji Won Yoo Ho Chuen Yuen Khalid Bin Waleed dong Chang Tong Liu Fang Zhou Liu Gary Tse Sharen Lee Ka Hou Christien Li Faculty of Pharmaceutical Sciences University of British ColumbiaBritish ColumbiaCanada Department of Medicine and Geriatrics Princess Margaret HospitalHong KongChina Department of Cardiology Fuwai Hospital Chinese Academy of Medical Sciences ShenzhenShenzhenChina Institute of Biomedicine and Biotechnology Shenzhen Institutes of Advanced TechnologyChinese Academy of SciencesShenzhenChina Xiamen Cardiovascular Hospital Xiamen UniversityXiamenChina Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of CardiologyTianjin Institute of CardiologyThe Second Hospital of Tianjin Medical UniversityTianjinChina Department of Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhouChina Faculty of Health and Medical Sciences University of SurreyGU27ALGuildfordUnited Kingdom Cardiovascular Analytics Group Laboratory of Cardiovascular PhysiologyHong KongChina Arrowe Park Acute Stroke Unit Wirral University Teaching Hospital NHS Foundation TrustWirralUK

BACKGROUND Postoperative atrial fibrillation(POAF)is a common yet understudied clinical issue after coronary artery bypass graft(CABG)leading to higher mortality rates and *** systematic review and metaanalysis evaluated the rates of adverse outcomes between patients with and without POAF in patients treated with CABG or combined *** The search period was from the beginning of PubMed and Embase to May 18th,2020 with no language *** inclusion criteria were:(1)studies comparing new onset atrial fibrillation before or after revascularization *** new onset AF before or after *** outcomes assessed included allcause mortality,cardiac death,cerebral vascular accident(CVA),myocardial infarction(MI),repeated revascularization,major adverse cardiac event(MACE),and major adverse cardiac and cerebrovascular events(MACCEs).RESULTS Of the 7,279 entries screened,11 studies comprising of 57,384 patients were *** to nonPOAF,POAF was significantly associated with higher risk of allcause mortality(Risk Ratio(RR)=1.58;95%Confidence Interval(CI):1.42−1.76,P<0.00001)with accompanying high level of heterogeneity(I^(2)=62%).Conclusions Patients with POAF after CABG or combined procedures are at an increased risk of allcause mortality or ***,POAF after such procedures should be closely monitored and treated judiciously to minimize risk of further *** there are studies on POAF versus no POAF on outcomes,the heterogeneity suggests that further studies are needed.

关键词： bypass fibrillation mortality

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World Journal of Gastroenterology 2008年第28期14卷 4535-4539页

作者： Guo-Shuang Feng Jun-Ling Ma Benjamin CY Wong Lian Zhang Wei-dong Liu Kai-Feng Pan Lin Shen Xiao-dong Zhang Jie Li Harry HX Xia Ji-You Li Shiu Kum lam Wei-Cheng You Department of Cancer Epidemiology Peking University School ofOncology Beijing Cancer Hospital & Institute Beijing 100036 China Department of Medicine University of Hong Kong Hong Kong China Department of Medical Oncology Peking University School of Oncology Beijing Cancer Hospital & Institute Beijing 100036 China Department of Pathology Peking University School of Oncology Beijing Cancer Hospital & Institute Beijing 100036 China Healthy Bureau of Linqu County Weifang 262600 Shandong Province China

AIM: To evaluate the long-term risk of gastroduodenal ulcer and cardiovascular events induced by celecoxib in a population-based, randomized, double-blind, placebo-controlled ***: From 2004 to 2006, a total of 1024 Chinese patients (aged 35 to 64 years) with severe chronic atrophic gastritis, intestinal metaplasia or dysplasia were randomly assigned to receive 200 mg of celecoxib twice daily or placebo in Linqu County (Shandong Province, China), a high-risk area of gastric cancer. All gastroduodenal ulcer and cardiovascular events occurred were recorded and the patients were followed up for 1.5 years after treatment. At the end of the trial, a systematic interview survey about other adverse events was conducted. RESULTS: Gastroduodenal ulcer was detected in 19 of 463 (3.72%) patients who received celecoxib and 17 of 473 (3.31%) patients who received placebo, respectively (odds ratio = 1.13, 95% CI = 0.58-2.19). Cardiovascular (CV) events occurred in 4 patients who received celecoxib and in 5 patients who received placebo, respectively. Compared with those who received placebo, patients who received celecoxib had no signif icant increase in occurrence of CV events (hazard ratio = 0.84, 95% CI = 0.23-3.15). Among the adverse events acquired by interview survey, only the frequency of bloating was signif icantly higher in patients treated with celecoxib than in those treated with placebo. CONCLUSION: Treatment of gastric cancer with celecoxib is not associated with increased risk of gastroduodenal ulcer and cardiovascular events.

关键词： Celecoxib Gastroduodenal ulcer Cardiovascular diseases Adverse effects Epidemiology Randomized controlled trial

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Antibiofilm activity of alpha-mangostin loaded nanoparticles against Streptococcus mutans

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Asian Pacific Journal of Tropical Biomedicine 2020年第7期10卷 325-332页

作者： Phuong T.M.Nguyen Minh T.H.Nguyen Lien T.Quach Phuong T.M.Nguyen lam L.Nguyen dong V.Quyen Institute of Biotechnology Vietnam Academy of Science and Technology18 Hoang Quoc Viet RoadHanoiVietnam Institute of Graduate University of Science and Technology Vietnam Academy of Science and Technology18 Hoang Quoc Viet RoadHanoiVietnam University of Science and Technology of Hanoi Vietnam Academy of Science and Technology18-Hoang Quoc Viet RoadCau GiayHanoiVietnam

Objective:To investigate the antibiofilm activity of alphamangostin(AMG)loaded nanoparticle(nano AMG)against dental caries pathogen Streptococcus ***:AMG was isolated from the peels of Garcinia mangostana *** silica gel columns and chemically analysed by high performance liquid chromatography and nuclear magnetic *** AMG was prepared using the solvent evaporation method combined with high-speed *** nanoparticles were characterized using dynamic light scattering,field emission scanning electron microscopy(FE-SEM)and Fourier transform infrared spectroscopy(FTIR).The toxicity of nano AMG in fibroblast NIH/3 T3 cell line was determined using MTT *** antibiofilm effect of nano AMG was determined through the evaluation of biofilm formation by Streptococcus mutans using a 96-well *** biomass was quantified using crystal *** viability was observed under confocal microscopy using LIVE/DEAD Bac Light ***,gene expression was determined by quantitative real-time PCR and membrane permeabilization activity by measuring the uptake of o-nitrophenol-β-***:Nano AMG size was in a range of 10-50 nm with a polydispersity index of<0.3 and zeta potential value of-35.2 m *** size and the incorporation of AMG in the nanoparticles were confirmed by FE-SEM and FTIR *** IC50 values of the test agents on NIH/3 T3 cells were(9.80±0.63)μg/m L for AMG and(8.70±0.81)μg/m L for nano AMG,while no toxicity was generated from excipients used to prepare *** the early stage of biofilm formation,treatment with 6.25μmol/L nano AMG caused a reduction in biofilm biomass up to 49.1%,compared to 33.4%for *** contrast,biofilms at the late stage were more resistant to the test *** 96μmol/L(=10×MIC),nano AMG reduced only 20.7%of biofilm biomass while AMG did not showany *** of gtf B and gtf C genes involved in biofilm formation were down-regulated 3.3 and 12.5 folds,res

关键词： Alpha-mangostin Nanoparticle Antibiofilm activity Streptococcus mutans

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废弃杨木水泥模板纤维特性及纤维板的研究

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浙江农林大学学报 2014年第6期31卷 940-946页

作者： PHAM Tuong lam 王新洲邓玉和董葛平 tran Minh Toi CAO Quoc An 南京林业大学材料科学与工程学院江苏南京210037 越南林业大学木材工程学院河内156204

以废弃杨木水泥模板纤维为原料制造纤维板,实现杨木的循环利用。对水泥模板以及分离好的纤维性能进行测试分析,并分别以废弃杨木水泥模板纤维、新鲜杨木纤维为原料制造不同密度的纤维板,讨论原料特性和施胶量对板材性能的影响。研究结... 详细信息

以废弃杨木水泥模板纤维为原料制造纤维板,实现杨木的循环利用。对水泥模板以及分离好的纤维性能进行测试分析,并分别以废弃杨木水泥模板纤维、新鲜杨木纤维为原料制造不同密度的纤维板,讨论原料特性和施胶量对板材性能的影响。研究结果表明:废弃杨木水泥模板表面碳元素含量高于杨木单板表面,而水泥模板表面的氧元素含量较低;废弃杨木水泥模板纤维的堆积密度与新鲜杨木纤维基本相同;当用水泥模板制得的纤维板密度达到0.75 g·cm-3时,板材的力学性能和吸水厚度膨胀率(TS)值均优于其他密度的板材,当施胶量大于等于12.0%时,板材的弹性模量(MOE),静曲强度(MOR),内结合强度(IB)性能均能满足国家标准值的要求。因此,废弃杨木水泥模板完全可以替代普通杨木制造纤维板。

关键词：木材科学与技术废弃杨木水泥模板纤维板物理力学性能施胶量

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Endogenous ceramide phosphoethanolamine modulates circadian rhythm via neural-glial coupling in Drosophila

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National Science Review 2022年第12期9卷 104-123页

作者： Xiupeng Chen Jie Li Zhongbao Gao Yang Yang Wenqing Kuang Yue dong Gek Huey Chua Xiahe Huang Binhua Jiang He Tian Yingchun Wang Xun Huang Yan Li Sin Man lam Guanghou Shui State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental Biology Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Brain and Cognitive Science Institute of Biophysics Chinese Academy of Sciences Lipid ALL Technologies Company Limited

While endogenous lipids are known to exhibit rhythmic oscillations,less is known about how specific lipids modulate circadian *** a series of loss-of-function and gain-of-function experiments on cer amide phosphoethanolamine(CPE) synthase of Drosophila,we demonstrated that pan-glial-specific deficiency in membrane CPE,the structural analog of mammalian sphingomyelin(SM),leads to arrhythmic locomotor behavior and shortens lifespan,while the reverse is true for increasing *** proteomics uncovered dysregulated synaptic glutamate utilization and transport in CPE-deficient *** extensive genetic screen was conducted to verify the role of differentially expressed proteins in circadian *** locomotion under cpes1mutant background was rescued only by restoring endogenous CPE or SM through expressing their respective *** results underscore the essential role of CPE in maintaining synaptic glutamate homeostasis and modulating circadian behavior in *** findings suggest that region-specific elevations of functional membrane lipids can benefit circadian regulation.

关键词： ceramide phosphoethanolamine sphingomyelin circadian longevity glutamate homeostasis

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LINEAR AND HYPERBRANCHED POLYMERS WITH HIGH THERMAL STABILITY AND LUMINESCENCE EFFICIENCY

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Chinese Journal of Polymer Science 2001年第6期19卷 585-590页

作者： Jacky Wing Yip lam Jing-dong Luo Han Peng Zhi-liang Xie Kai-tian Xue Yu-ping dong Lin Cheng Cheng-feng Qiu Hoi Sing Kwok Ben-zhong Tang Departments of Chemistry and Electrical & Electronic Engineering Hong Kong University of Science & Technology Clear Water Bay, Kowloon, Hong Kong China 香港科技大学香港

New acetylene monomers, 6-{[(1-naphthylethynyl-4-phenyl)carbonyl]oxy}-1-phenyl-1-hexyne (1), 2,5-diethynyl-thiophene (3), and 4,4'-diethynylbiphenyl (6) were synthesized. Homopolymerization of 1 and copolycyclotrimerizations of 3 and 6 with 1-heptyne and 1-octyne have been achieved with WCl6- and TaCl5-Ph4Sn catalysts, respectively, giving soluble linear disubstituted polyacetylene (2) and hyperbranched polyarylenes (5 and 8) with high molecular weights (up to 1.2 x 10(5)) in high yields (up to 98%). The structures and properties of the polymers are characterized and evaluated by R NMR, TGA, UV, photoluminescence (PL), and electroluminescence (EL) analyses. All the polymers possess high thermal stability and emit strong blue light upon photoexcitation. The intensity of the emitted light is greater than that of poly(1-phenyl-1-octyne), a well-known highly luminescent disubstituted polyacetylene. Little aggregation-induced red shift in the PL was observed in the thin films of the polymers. By constructing a multi-layer EL device, high EL quantum yield (0.18%) has been achieved in 2, which are the best results for substituted polyacetylenes attainable so far.

关键词： disubstituted polyacetylene hyperbranched polyarylene light emission

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Synthesis of cation exchange resin-supported iron and magnesium oxides/hydroxides composite for nitrate removal in water

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Chinese Journal of Chemical Engineering 2021年第4期34卷 378-384页

作者： Trung Thanh Nguyen Vu Anh Khoa tran Le Ba tran Phuoc Toan Phan Minh Tan Nguyen Long Giang Bach Surapol Padungthon Cong Khiem Ta Nhat Huy Nguyen Nanomaterial Laboratory An Giang University18 Ung Van Khiem St.Dong Xuyen DistLong Xuyen CityAn Giang ProvinceViet Nam Vietnam National University Ho Chi Minh City Linh Trung WardThu Duc DistrictHo Chi Minh CityViet Nam Faculty of Natural Resources and Environment Ho Chi Minh City University of Technology(HCMUT)268 Ly Thuong Kiet St.Dist.10Ho Chi Minh CityViet Nam Faculty of Engineering-Technology-Environment An Giang University18 Ung Van Khiem StDong Xuyen DistLong Xuyen CityAn Giang ProvinceViet Nam Department of Scientific Research and International Relation Bac Lieu University178 Vo Thi Sau St.Ward 8Bac Lieu CityBac Lieu ProvinceViet Nam NTT Institute of High Technology Nguyen Tat Thanh University298-300A Nguyen Tat ThanhHo Chi Minh CityViet Nam Department of Environmental Engineering Khon Kaen University123 Moo 16 Mittraphap Rd.Nai-MuangMuang DistrictKhon Kaen 40002Thailand

In this study,we reported on the concept and practical use of cation exchange resin(CER)for removing anions in water via pretreating the CER with metal *** cation exchange resinsupported iron and magnesium oxides/hydroxides composite(FeMg/CER)was synthesized and introduced as a new and potential adsorbent for selective removal of nitrate ion in the water *** of FeMg/CER were determined by techniques such as Fouriertransform infrared spectroscopy,scanning electron microscopy,and Xray *** results showed that FeMg/CER material had a high nitrate adsorption capacity of 200 mg NO_(3)^()·g^(1)with a fast equilibrium adsorption time of 30 min at pH *** addition,it had good durability of at least 10 times of regeneration,which could be applied to practical water and wastewater treatment.

关键词： Iron oxide/hydroxide Magnesium oxide/hydroxide Cation exchange resin Adsorption Environment Nanomaterials

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Real-world Effectiveness and Tolerability of Interferonfree Direct-acting Antiviral for 15,849 Patients with Chronic Hepatitis C:A Multinational Cohort Study

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Journal of Clinical and translational Hepatology 2024年第7期12卷 646-658页

作者： Fanpu Ji Sally tran Eiichi Ogawa Chung-Feng Huang Takanori Suzuki Yu Jun Wong Hidenori Toyoda Dae Won Jun Liu Li Haruki Uojima Akito Nozaki Makoto Chuma Cheng-Hao Tseng Yao-Chun Hsu Masatoshi Ishigami Takashi Honda Masanori Atsukawa Hiroaki Haga Masaru Enomoto Huy Trinh Carmen Monica Preda Phillip Vutien Charles Landis dong Hyun Lee Tsunamasa Watanabe Hirokazu Takahashi Hiroshi Abe Akira Asai Yuichiro Eguchi Jie Li Xiaozhong Wang Jia Li Junping Liu Jing Liang Carla Pui-Mei lam Rui Huang Qing Ye Hongying Pan Jiajie Zhang Dachuan Cai Qi Wang Daniel Q.Huang Grace Wong Vincent Wai-Sun Wong Junyi Li Son Do Norihiro Furusyo Makoto Nakamuta Hideyuki Nomura Eiji Kajiwara Eileen L.Yoon Sang Bong Ahn Koichi Azuma Kazufumi Dohmen Jihyun An Do Seon Song Hyun Chin Cho Akira Kawano Toshimasa Koyanagi Aritsune Ooho Takeaki Satoh Kazuhiro Takahashi Ming-Lun Yeh Pei-Chien Tsai Satoshi Yasuda Yunyu Zhao Yishan Liu Tomomi Okubo Norio Itokawa Mi Jung Jun Toru Ishikawa Koichi Takaguchi Tomonori Senoh Mingyuan Zhang Changqing Zhao Raluca Ioana Alecu Wei Xuan Tay Pooja Devan Joanne Kimiko Liu Ritsuzo Kozuka Elena Vargas-Accarino Ai-Thien Do Mayumi Maeda Wan-Long Chuang Jee-Fu Huang Chia-Yen Dai Ramsey Cheung Maria Buti Junqi Niu Wen Xie Hong Ren Seng Gee Lim Chao Wu Man-Fung Yuen Jia Shang Qiang Zhu Yoshiyuki Ueno Yasuhito Tanaka Jun Hayashi Ming-Lung Yu Mindie H.Nguyen Department of Infectious Diseases The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxiChina Division of Gastroenterology and Hepatology Department of MedicineStanford University Medical CenterPalo AltoCAUSA Department of General Internal Medicine Kyushu University HospitalFukuokaJapan Hepatobiliary Division Department of Internal MedicineKaohsiung Medical University HospitalKaohsiung Hepatitis Research Center College of Medicine and Center for Liquid Biopsy and Cohort ResearchKaohsiung Medical UniversityKaohsiung Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical SciencesNagoyaJapan Gastroenterology&Hepatology Changi General HospitalSinghealthSingapore Singhealth Duke-NUS Medicine Academic Clinical Program Singapore Department of Gastroenterology Ogaki Municipal HospitalOgakiJapan Department of Internal Medicine Hanyang UniversityCollege of MedicineSeoulKorea Hanyang Institute of Bioscience and Biotechnology Hanyang UniversitySeoulKorea Department of Hepatology The Third People's Hospital of Kunming CityKunmingYunnanChina Department of Gastroenterology Internal MedicineKitasato University School of MedicineSagamiharaJapan Gastroenterological Center Yokohama City University Medical CenterYokohamaJapan Division of Gastroenterology and Hepatology Department of Internal MedicineE-Da Cancer HospitalKaohsiung Department of Gastroenterology and Hepatology Nagoya University Graduate School of MedicineNagoyaJapan Division of Gastroenterology and Hepatology Nippon Medical SchoolTokyoJapan Department of Gastroenterology Yamagata University Faculty of MedicineYamagataJapan Department of transfusion Medicine and Department of Hepatology Osaka Metropolitan University Graduate School of MedicineOsakaJapan San Jose Gastroenterology San JoseCAUSA Gastroenterology&Hepatology Department Clinic Fundeni InstituteBucharestRomania Division of Gastroenterology and Hepatology University of WashingtonSeattleWAUSA Department of

Background and Aims:As practice patterns and hepatitis C virus(HCV)genotypes(GT)vary geographically,a global real-world study from both East and West covering all GTs can help inform practice policy toward the 2030 HCV elimination *** study aimed to assess the effectiveness and tolerability of DAA treatment in routine clinical practice in a multinational cohort for patients infected with all HCV GTs,focusing on GT3 and ***:We analyzed the sustained virological response(SVR12)of 15,849 chronic hepatitis C patients from 39 Real-World Evidence from the Asia Liver Consortium for HCV clinical sites in Asia Pacific,North America,and Europe between 07/01/2014–07/01/***:The mean age was 62±13 years,with 49.6%*** demographic breakdown was 91.1%Asian(52.9%Japanese,25.7%Chinese/Taiwan residents,5.4%Korean,3.3%Malaysian,and 2.9%Vietnamese),6.4%White,1.3%Hispanic/Latino,and 1%Black/***,34.8%had cirrhosis,8.6%had hepatocellular carcinoma(HCC),and 24.9%were treatment-experienced(20.7%with interferon,4.3%with direct-acting antivirals).The largest group was GT1(10,246[64.6%]),followed by GT2(3,686[23.2%]),GT3(1,151[7.2%]),GT6(457[2.8%]),GT4(47[0.3%]),GT5(1[0.006%]),and untyped GTs(261[1.6%]).The overall SVR12 was 96.9%,with rates over 95%for GT1/2/3/6 but 91.5%for ***12 for GT3 was 95.1%overall,98.2%for GT3a,and 94.0%for ***12 was 98.3%overall for GT6,lower for patients with cirrhosis and treatment-experienced(TE)(93.8%)but≥97.5%for tretment-naive patients regardless of cirrhosis *** multivariable analysis,advanced age,prior treatment failure,cirrhosis,active HCC,and GT3/4 were independent predictors of lower SVR12,while being Asian was a significant predictor of achieving ***:In this diverse multinational realworld cohort of patients with various GTs,the overall cure rate was 96.9%,despite large numbers of patients with cirrhosis,HCC,TE,and GT3/***12 for GT3/6 with cirrhosis and TE was lower but st

关键词： Hepatitis C virus Liver cirrhosis Hepatocellular carcinoma Genotype DAA REAL-C

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Improved knowledge-based neural network(KBNN)model for predicting spring-back angles in metal sheet bending

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International Journal of Modeling, Simulation, and Scientific Computing 2014年第2期5卷 65-91页

作者： Tinh Quoc Bui Anh Viet tran Abid Ali Shah Department of Civil Engineering University of Siegen Paul-Bontz-Str.9-1157076 SiegenGermany School of Mechanical and Automotive Engineering University of Ulsan San 29Mugeo 2-dong NamguP.O.Box 18UlsanSouth Korea

We develop an efficiently improved knowledge-based neural network(KBNN)associated with optimization algorithms and finite element analysis(FEA)to accurately predict spring-back angles in metal sheet *** well-known V and U prevalent processes of bending are *** KBNN predictive results are based on the empirical model and artificial neural network(ANN)*** empirical model is constructed from the FEA results using response surface method,while the multilayer perceptron is employed to create the *** trained KBNN can accurately model the relation-ship between the spring-back angles and process *** obtained results are validated against other existing methods showing a high accuracy.

关键词： Metal sheet bending spring-back angles knowledge-based neural network genetic algorithm optimization algorithm

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An Analytical Approach for Nonlinear Buckling Analysis of Torsionally Loaded Sandwich Carbon Nanotube Reinforced Cylindrical Shells with Auxetic Core

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Advances in Applied Mathematics and Mechanics 2023年第2期15卷 468-484页

作者： Dang Thuy dong Nguyen Thi Phuong Vu Hoai Nam Le Ngoc Ly Nguyen Van Tien Vu Minh Duc tran Quang Minh Vu Tho Hung Nguyen Thi Huong Giang Faculty of Civil Engineering University of Transport TechnologyHanoi 100000Vietnam Graduate School of Advanced Science and Engineering Hiroshima University1-4-1 KagamiyamaHigashi-HiroshimaHiroshima 739-8527Japan Faculty of Fundamental Science for Engineering University of Transport TechnologyHanoi 100000Vietnam

The main aim of this paper is to present an analytical approach on the postbuckling for torsionally loaded sandwich carbon nanotube(CNT)reinforced cylindrical shells with the auxetic *** considered shells consist of three layers,external and internal CNT reinforced layers,and the auxetic lattice core made by isotropic *** homogenization model for honeycomb auxetic lattice core is utilized,and the equilibrium equations are formulated based on the nonlinear Donnell’s thin shell theory with von Karman geometrical *** three terms of deflection are considered,the Airy’s stress function and Galerkin’s method are utilized,the explicit expression of critical buckling of torsionally loaded shells and load-deflection expression of postbuckling states are *** effects of two carbon nanotube reinforced layers,the auxetic core layer,the volume fraction of carbon nanotube on the torsional buckling behavior are examined and remarked.

关键词： Nonlinear postbuckling carbon nanotube reinforced composite cylindrical shell torsion auxetic core

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